PubRank

G McFadden

Author PubWeight™ 129.68‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB. Neuron 1990 3.70
2 The complete DNA sequence of myxoma virus. Virology 1999 2.44
3 Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences. Mol Cell Biol 1988 2.40
4 Biogenesis of vaccinia: isolation of conditional lethal mutants and electron microscopic characterization of their phenotypically expressed defects. Virology 1978 2.09
5 Encoding of a homolog of the IFN-gamma receptor by myxoma virus. Science 1992 2.07
6 Identification of a gammaherpesvirus selective chemokine binding protein that inhibits chemokine action. J Virol 2000 1.86
7 Virus-encoded serine proteinase inhibitor SERP-1 inhibits atherosclerotic plaque development after balloon angioplasty. Circulation 1996 1.86
8 Modulating chemokines: more lessons from viruses. Immunol Today 2000 1.85
9 Apoptosis: an innate immune response to virus infection. Trends Microbiol 1999 1.82
10 The complete genome sequence of shope (rabbit) fibroma virus. Virology 1999 1.73
11 The T1/35kDa family of poxvirus-secreted proteins bind chemokines and modulate leukocyte influx into virus-infected tissues. Virology 1997 1.72
12 Sequence-nonspecific replication of transfected plasmid DNA in poxvirus-infected cells. Proc Natl Acad Sci U S A 1986 1.71
13 T2 open reading frame from the Shope fibroma virus encodes a soluble form of the TNF receptor. Biochem Biophys Res Commun 1991 1.64
14 Species specificity of ectromelia virus and vaccinia virus interferon-gamma binding proteins. Virology 1995 1.64
15 Deletion analysis of two tandemly arranged virulence genes in myxoma virus, M11L and myxoma growth factor. J Virol 1992 1.59
16 Replication and resolution of cloned poxvirus telomeres in vivo generates linear minichromosomes with intact viral hairpin termini. J Virol 1986 1.53
17 The site-specific cleavage of synthetic Holliday junction analogs and related branched DNA structures by bacteriophage T7 endonuclease I. J Biol Chem 1987 1.52
18 High levels of genetic recombination among cotransfected plasmid DNAs in poxvirus-infected mammalian cells. J Virol 1988 1.50
19 SERP1, a serine proteinase inhibitor encoded by myxoma virus, is a secreted glycoprotein that interferes with inflammation. Virology 1993 1.49
20 A poxvirus-encoded uracil DNA glycosylase is essential for virus viability. J Virol 1993 1.45
21 Use of chemokine receptors by poxviruses. Science 1999 1.43
22 The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines. J Virol 1997 1.43
23 M11L: a novel mitochondria-localized protein of myxoma virus that blocks apoptosis of infected leukocytes. J Exp Med 2000 1.39
24 Myxoma virus expresses a secreted protein with homology to the tumor necrosis factor receptor gene family that contributes to viral virulence. Virology 1991 1.39
25 Myxoma virus and malignant rabbit fibroma virus encode a serpin-like protein important for virus virulence. Virology 1990 1.38
26 Disruption of M-T5, a novel myxoma virus gene member of poxvirus host range superfamily, results in dramatic attenuation of myxomatosis in infected European rabbits. J Virol 1996 1.37
27 Myxoma virus M-T5 protects infected cells from the stress of cell cycle arrest through its interaction with host cell cullin-1. J Virol 2005 1.33
28 Biogenesis of poxviruses: mirror-image deletions in vaccinia virus DNA. Cell 1979 1.30
29 Immunomodulation by viruses: the myxoma virus story. Immunol Rev 1999 1.28
30 Expression of the myxoma virus tumor necrosis factor receptor homologue and M11L genes is required to prevent virus-induced apoptosis in infected rabbit T lymphocytes. Virology 1996 1.27
31 Differential inhibition of the Fas- and granule-mediated cytolysis pathways by the orthopoxvirus cytokine response modifier A/SPI-2 and SPI-1 protein. Proc Natl Acad Sci U S A 1996 1.27
32 Identification of a poxvirus gene encoding a uracil DNA glycosylase. Proc Natl Acad Sci U S A 1993 1.25
33 Mutations in active-site residues of the uracil-DNA glycosylase encoded by vaccinia virus are incompatible with virus viability. J Virol 1996 1.25
34 Myxoma virus M-T7, a secreted homolog of the interferon-gamma receptor, is a critical virulence factor for the development of myxomatosis in European rabbits. Virology 1996 1.24
35 Myxoma virus targets primary human leukemic stem and progenitor cells while sparing normal hematopoietic stem and progenitor cells. Leukemia 2009 1.22
36 Mechanism of replication of phi x174 single-stranded DNA. IX. Requirement for the Escherichia coli dnaG protein. J Virol 1974 1.21
37 The genome of Shope fibroma virus, a tumorigenic poxvirus, contains a growth factor gene with sequence similarity to those encoding epidermal growth factor and transforming growth factor alpha. Mol Cell Biol 1987 1.19
38 Identification and DNA sequence of the large subunit of the capping enzyme from Shope fibroma virus. Virology 1991 1.19
39 Mapping and sequencing of a gene from myxoma virus that is related to those encoding epidermal growth factor and transforming growth factor alpha. J Virol 1987 1.16
40 Physical characterization and molecular cloning of the Shope fibroma virus DNA genome. Virology 1983 1.16
41 Tumorigenic poxviruses: analysis of viral DNA sequences implicated in the tumorigenicity of Shope fibroma virus and malignant rabbit virus. Virology 1986 1.16
42 Immunomodulatory proteins of myxoma virus. Semin Immunol 2001 1.14
43 The viral anti-inflammatory chemokine-binding protein M-T7 reduces intimal hyperplasia after vascular injury. J Clin Invest 2000 1.12
44 Identification and nucleotide sequence of the thymidine kinase gene of Shope fibroma virus. J Virol 1986 1.09
45 Tumorigenic poxviruses: genomic organization and DNA sequence of the telomeric region of the Shope fibroma virus genome. Virology 1987 1.09
46 Cruciform extrusion in plasmids bearing the replicative intermediate configuration of a poxvirus telomere. J Mol Biol 1987 1.07
47 The myxoma virus-soluble interferon-gamma receptor homolog, M-T7, inhibits interferon-gamma in a species-specific manner. J Biol Chem 1995 1.07
48 Functional comparisons among members of the poxvirus T1/35kDa family of soluble CC-chemokine inhibitor glycoproteins. Virology 1998 1.06
49 The myxoma virus M-T4 gene encodes a novel RDEL-containing protein that is retained within the endoplasmic reticulum and is important for the productive infection of lymphocytes. Virology 1997 1.06
50 Inhibition of plasmin, urokinase, tissue plasminogen activator, and C1S by a myxoma virus serine proteinase inhibitor. J Biol Chem 1993 1.06
51 Biogenesis of poxviruses: role for the DNA-dependent RNA polymerase II of the host during expression of late functions. Proc Natl Acad Sci U S A 1979 1.05
52 The target DNA sequence for resolution of poxvirus replicative intermediates is an active late promoter. J Virol 1991 1.04
53 Myxoma virus M11L ORF encodes a protein for which cell surface localization is critical in manifestation of viral virulence. Virology 1992 1.04
54 The myxoma virus TNF-receptor homologue (T2) inhibits tumor necrosis factor-alpha in a species-specific fashion. Virology 1994 1.03
55 Efficient resolution of replicated poxvirus telomeres to native hairpin structures requires two inverted symmetrical copies of a core target DNA sequence. J Virol 1987 1.03
56 Biogenesis of poxviruses: preliminary characterization of conditional lethal mutants of vaccinia virus defective in DNA synthesis. Virology 1980 1.02
57 Cloning and sequencing of the cytoplasmic precursor to the alpha subunit of rat liver mitochondrial succinyl-CoA synthetase. Proc Natl Acad Sci U S A 1988 1.02
58 Inhibitory specificity of the anti-inflammatory myxoma virus serpin, SERP-1. J Biol Chem 1998 1.01
59 Molecular determinants for CC-chemokine recognition by a poxvirus CC-chemokine inhibitor. Proc Natl Acad Sci U S A 2001 1.01
60 Optical detection of triggered atherosclerotic plaque disruption by fluorescence emission analysis. Photochem Photobiol 2000 1.01
61 Tumorigenic poxviruses: genomic organization of malignant rabbit virus, a recombinant between Shope fibroma virus and myxoma virus. Virology 1985 1.01
62 Role of the myxoma virus soluble CC-chemokine inhibitor glycoprotein, M-T1, during myxoma virus pathogenesis. Virology 1999 1.00
63 Viruses and apoptosis: meddling with mitochondria. Virology 2001 1.00
64 Tumorigenic poxviruses: construction of the composite physical map of the Shope fibroma virus genome. J Virol 1984 1.00
65 Virus-induced loss of class I MHC antigens from the surface of cells infected with myxoma virus and malignant rabbit fibroma virus. J Immunol 1992 0.99
66 The viral tropism of two distinct oncolytic viruses, reovirus and myxoma virus, is modulated by cellular tumor suppressor gene status. Oncogene 2010 0.98
67 In vitro resolution of poxvirus replicative intermediates into linear minichromosomes with hairpin termini by a virally induced Holliday junction endonuclease. J Virol 1992 0.98
68 Secreted poxvirus chemokine binding proteins. J Leukoc Biol 1997 0.98
69 Amelioration of antigen induced arthritis in rabbits treated with a secreted viral serine proteinase inhibitor. J Rheumatol 1996 0.97
70 The role of telomeres in poxvirus DNA replication. Curr Top Microbiol Immunol 1990 0.96
71 Poxvirus infection rapidly activates tyrosine kinase signal transduction. J Biol Chem 2001 0.96
72 Apoptosis regulators from DNA viruses. Curr Opin Immunol 1998 0.95
73 Distinct domains of M-T2, the myxoma virus tumor necrosis factor (TNF) receptor homolog, mediate extracellular TNF binding and intracellular apoptosis inhibition. J Virol 1997 0.95
74 Myxoma virus T2 protein, a tumor necrosis factor (TNF) receptor homolog, is secreted as a monomer and dimer that each bind rabbit TNFalpha, but the dimer is a more potent TNF inhibitor. J Biol Chem 1996 0.95
75 A poxvirus protein with a RING finger motif binds zinc and localizes in virus factories. J Virol 1994 0.94
76 Evasion and exploitation of chemokines by viruses. Cytokine Growth Factor Rev 2000 0.93
77 Myxoma virus induces extensive CD4 downregulation and dissociation of p56lck in infected rabbit CD4+ T lymphocytes. J Virol 1995 0.93
78 Cloning of the vaccinia virus telomere in a yeast plasmid vector. Gene 1984 0.91
79 Role of the C-terminal RDEL motif of the myxoma virus M-T4 protein in terms of apoptosis regulation and viral pathogenesis. Virology 1999 0.91
80 Deletion of the growth factor gene related to EGF and TGF alpha reduces virulence of malignant rabbit fibroma virus. Virology 1992 0.91
81 Tumorigenic poxviruses: fine analysis of the recombination junctions in malignant rabbit fibroma virus, a recombinant between Shope fibroma virus and myxoma virus. Virology 1988 0.89
82 Inhibition of transplant vasculopathy in a rat aortic allograft model after infusion of anti-inflammatory viral serpin. Circulation 2000 0.89
83 Virus encoded cytokines and cytokine receptors. Parasitology 1997 0.89
84 DNA sequence homology between the terminal inverted repeats of Shope fibroma virus and an endogenous cellular plasmid species. Mol Cell Biol 1986 0.88
85 Transforming growth factor alpha, Shope fibroma growth factor, and vaccinia growth factor can replace myxoma growth factor in the induction of myxomatosis in rabbits. Virology 1993 0.88
86 Glycosaminoglycan binding properties of the myxoma virus CC-chemokine inhibitor, M-T1. J Biol Chem 2001 0.88
87 Endosomal/lysosomal retention and degradation of major histocompatibility complex class I molecules is induced by myxoma virus. Virology 1999 0.88
88 Identification and DNA sequence of the Shope fibroma virus DNA topoisomerase gene. Virology 1990 0.88
89 Mutational analysis of the ligand-binding domain of M-T2 protein, the tumor necrosis factor receptor homologue of myxoma virus. J Immunol 1996 0.87
90 The mechanism of replication of phi X174 single-stranded DNA. VI. Requirements for ribonucleoside triphosphates and DNA polymerase 3. Can J Biochem 1973 0.87
91 The mechanism of replication of phiX174 DNA. XIII. Discontinuous synthesis of the complementary strand in an Escherichia coli host with a temperature-sensitive polynucleotide ligase. J Mol Biol 1975 0.86
92 Myxoma virus and Shope fibroma virus encode dual-specificity tyrosine/serine phosphatases which are essential for virus viability. Virology 1995 0.84
93 Preliminary characterisation of chlorarachniophyte mitochondrial DNA. J Eukaryot Microbiol 1996 0.83
94 Myxoma virus expresses a TNF receptor homolog with two distinct functions. Virus Genes 2000 0.83
95 Organization of two genes encoding cytotoxic T lymphocyte-specific serine proteases CCPI and CCPII. Biochemistry 1988 0.83
96 Post-translational modification of the myxoma-virus anti-inflammatory serpin SERP-1 by a virally encoded sialyltransferase. Biochem J 2000 0.83
97 M-T2: a poxvirus TNF receptor homologue with dual activities. Immunol Cell Biol 1996 0.82
98 Regulation of nitric oxide synthase 2 in rabbit corneal cells. Invest Ophthalmol Vis Sci 2001 0.82
99 Tumorigenic poxviruses: characterization of an early promoter from Shope fibroma virus. Virology 1989 0.81
100 Transcriptional regulation of two cytotoxic T lymphocyte-specific serine protease genes. Nucleic Acids Res 1989 0.81
101 Transplant vasculopathy: viral anti-inflammatory serpin regulation of atherogenesis. J Heart Lung Transplant 2000 0.81
102 Tumorigenic poxviruses: transcriptional mapping of the terminal inverted repeats of Shope fibroma virus. Virology 1987 0.80
103 Chloroplasts. Ever decreasing circles. Nature 1999 0.80
104 A new endonuclease restriction site which is at the locus of a temperature-sensitive mutation in vaccinia virus is associated with true and pseudoreversion. Virology 1980 0.79
105 Biogenesis of poxviruses: transitory expression of Molluscum contagiosum early functions. Virology 1979 0.79
106 Contrasting effects of 2',3'-dideoxyadenosine on two steps in the replication of phi X 174 DNA in Escherichia coli. Virology 1977 0.79
107 Nucleotide sequence analysis of a unique near-terminal region of the tumorigenic poxvirus, Shope fibroma virus. J Gen Virol 1992 0.79
108 DNA cruciform structures: implications for telomer replication in eukaryotes and instability of long palindromic DNA sequences in prokaryotes. J Theor Biol 1982 0.78
109 Harvesting viral proteins. CMAJ 1999 0.78
110 Tumorigenic poxviruses: characterization of the expression of an epidermal growth factor related gene in Shope fibroma virus. Virology 1990 0.78
111 Viral proteins and the mitochondrial apoptotic checkpoint. Cytokine Growth Factor Rev 2001 0.77
112 Application of linear free energy relationships to the serpin-proteinase inhibition mechanism. FEBS Lett 2000 0.76
113 Characterization of the myxoma virus M118L protein: a novel essential poxvirus IMV-associated protein. Virus Genes 2001 0.75
114 Health care delivery in a sleep center. Sleep Breath 1997 0.75
115 Location of a new endonuclease restriction site associated with a temperature-sensitive mutation of vaccinia virus. Virology 1980 0.75
116 SERP-1, a poxvirus-encoded serpin, is expressed as a secreted glycoprotein that inhibits the inflammatory response to myxoma virus infection. Adv Exp Med Biol 1997 0.75
117 Detection of transplant vasculopathy in a rat aortic allograft model by fluorescence spectroscopic optical analysis. Lasers Surg Med 1999 0.75
118 Conformational isomerization of the Holliday junction associated with a cruciform during branch migration in supercoiled plasmid DNA. J Mol Biol 1988 0.75
119 A novel member of the serpin superfamily is encoded on a circular plasmid-like DNA species isolated from rabbit cells. FEBS Lett 1986 0.75
120 Lead your maimed patient back to independence. RN 1977 0.75