Published in Virology on November 25, 1999
Poxvirus orthologous clusters: toward defining the minimum essential poxvirus genome. J Virol (2003) 2.70
Infection of human cancer cells with myxoma virus requires Akt activation via interaction with a viral ankyrin-repeat host range factor. Proc Natl Acad Sci U S A (2006) 1.96
Extensive gene gain associated with adaptive evolution of poxviruses. Proc Natl Acad Sci U S A (2003) 1.90
Role of the serine-threonine kinase PAK-1 in myxoma virus replication. J Virol (2003) 1.69
The genomes of sheeppox and goatpox viruses. J Virol (2002) 1.68
Functional diversity of ankyrin repeats in microbial proteins. Trends Microbiol (2009) 1.58
The PHD/LAP-domain protein M153R of myxomavirus is a ubiquitin ligase that induces the rapid internalization and lysosomal destruction of CD4. J Virol (2003) 1.52
Targeting human medulloblastoma: oncolytic virotherapy with myxoma virus is enhanced by rapamycin. Cancer Res (2007) 1.50
A Shope Fibroma virus PYRIN-only protein modulates the host immune response. Virus Genes (2007) 1.41
Vaccinia virus F12L protein is required for actin tail formation, normal plaque size, and virulence. J Virol (2000) 1.38
Myxoma virus M-T5 protects infected cells from the stress of cell cycle arrest through its interaction with host cell cullin-1. J Virol (2005) 1.33
Biological characterization and next-generation genome sequencing of the unclassified Cotia virus SPAn232 (Poxviridae). J Virol (2012) 1.33
Species-level identification of orthopoxviruses with an oligonucleotide microchip. J Clin Microbiol (2002) 1.33
The genome of swinepox virus. J Virol (2002) 1.30
Myxoma virus: propagation, purification, quantification, and storage. Curr Protoc Microbiol (2010) 1.29
Myxoma virus M11L prevents apoptosis through constitutive interaction with Bak. J Virol (2004) 1.27
A virulence factor of myxoma virus colocalizes with NF-kappaB in the nucleus and interferes with inflammation. J Virol (2004) 1.26
Bacterial cryptochrome and photolyase: characterization of two photolyase-like genes of Synechocystis sp. PCC6803. Nucleic Acids Res (2000) 1.25
Evolutionary history and attenuation of myxoma virus on two continents. PLoS Pathog (2012) 1.22
Myxoma virus M141R expresses a viral CD200 (vOX-2) that is responsible for down-regulation of macrophage and T-cell activation in vivo. J Virol (2005) 1.20
Genome of lumpy skin disease virus. J Virol (2001) 1.17
Myxoma virus oncolysis of primary and metastatic B16F10 mouse tumors in vivo. Mol Ther (2007) 1.16
Characterization of a newly identified 35-amino-acid component of the vaccinia virus entry/fusion complex conserved in all chordopoxviruses. J Virol (2009) 1.16
Poxviruses and the evolution of host range and virulence. Infect Genet Evol (2013) 1.16
Kaposi's sarcoma-associated herpesvirus OX2 glycoprotein activates myeloid-lineage cells to induce inflammatory cytokine production. J Virol (2002) 1.13
The phylogenetics and ecology of the orthopoxviruses endemic to North America. PLoS One (2009) 1.12
A glutaredoxin, encoded by the G4L gene of vaccinia virus, is essential for virion morphogenesis. J Virol (2000) 1.11
Vaccinia virus F1L protein is a tail-anchored protein that functions at the mitochondria to inhibit apoptosis. J Virol (2005) 1.08
The vaccinia virus A14.5L gene encodes a hydrophobic 53-amino-acid virion membrane protein that enhances virulence in mice and is conserved among vertebrate poxviruses. J Virol (2000) 1.08
Vaccinia virus J1R protein: a viral membrane protein that is essential for virion morphogenesis. J Virol (2002) 1.08
CrmE, a novel soluble tumor necrosis factor receptor encoded by poxviruses. J Virol (2001) 1.07
Genome of crocodilepox virus. J Virol (2006) 1.06
Complete genomic sequence and comparative analysis of the tumorigenic poxvirus Yaba monkey tumor virus. J Virol (2003) 1.05
Myxoma virus expressing interleukin-15 fails to cause lethal myxomatosis in European rabbits. J Virol (2009) 1.04
The immunoregulatory properties of oncolytic myxoma virus and their implications in therapeutics. Microbes Infect (2010) 1.03
Viral biocontrol: grand experiments in disease emergence and evolution. Trends Microbiol (2014) 1.03
Vaccinia virus-encoded ribonucleotide reductase subunits are differentially required for replication and pathogenesis. PLoS Pathog (2010) 1.03
Vaccinia viruses with mutations in the E3L gene as potential replication-competent, attenuated vaccines: intra-nasal vaccination. Vaccine (2007) 1.02
Genome comparison of a nonpathogenic myxoma virus field strain with its ancestor, the virulent Lausanne strain. J Virol (2008) 1.02
The vaccinia virus superoxide dismutase-like protein (A45R) is a virion component that is nonessential for virus replication. J Virol (2001) 1.00
Genome of deerpox virus. J Virol (2005) 1.00
M148R and M149R are two virulence factors for myxoma virus pathogenesis in the European rabbit. Vet Res (2008) 0.98
Myxoma virus and the Leporipoxviruses: an evolutionary paradigm. Viruses (2015) 0.96
Genome scale evolution of myxoma virus reveals host-pathogen adaptation and rapid geographic spread. J Virol (2013) 0.96
Fowlpox virus encodes a Bcl-2 homologue that protects cells from apoptotic death through interaction with the proapoptotic protein Bak. J Virol (2007) 0.96
The myxoma virus m-t5 ankyrin repeat host range protein is a novel adaptor that coordinately links the cellular signaling pathways mediated by Akt and Skp1 in virus-infected cells. J Virol (2009) 0.95
Oncolytic myxoma virus: the path to clinic. Vaccine (2013) 0.95
Genetic variation at chemokine receptor CCR5 in leporids: alteration at the 2nd extracellular domain by gene conversion with CCR2 in Oryctolagus, but not in Sylvilagus and Lepus species. Immunogenetics (2006) 0.95
M135R is a novel cell surface virulence factor of myxoma virus. J Virol (2006) 0.94
Myxoma and vaccinia viruses exploit different mechanisms to enter and infect human cancer cells. Virology (2010) 0.93
Identification and characterization of a spliced C-type lectin-like gene encoded by rat cytomegalovirus. J Virol (2001) 0.91
Myxoma and vaccinia viruses bind differentially to human leukocytes. J Virol (2013) 0.90
Comparative analysis of poxvirus orthologues of the vaccinia virus E3 protein: modulation of protein kinase R activity, cytokine responses, and virus pathogenicity. J Virol (2011) 0.90
The current status and future directions of myxoma virus, a master in immune evasion. Vet Res (2011) 0.90
Poxvirus tumor necrosis factor receptor (TNFR)-like T2 proteins contain a conserved preligand assembly domain that inhibits cellular TNFR1-induced cell death. J Virol (2006) 0.89
Fowlpox virus encodes a novel DNA repair enzyme, CPD-photolyase, that restores infectivity of UV light-damaged virus. J Virol (2001) 0.88
MNF, an ankyrin repeat protein of myxoma virus, is part of a native cellular SCF complex during viral infection. Virol J (2010) 0.87
Myxoma virus M064 is a novel member of the poxvirus C7L superfamily of host range factors that controls the kinetics of myxomatosis in European rabbits. J Virol (2012) 0.87
Myxoma virus M156 is a specific inhibitor of rabbit PKR but contains a loss-of-function mutation in Australian virus isolates. Proc Natl Acad Sci U S A (2016) 0.86
Deerpox virus encodes an inhibitor of apoptosis that regulates Bak and Bax. J Virol (2010) 0.86
Amsacta moorei entomopoxvirus expresses an active superoxide dismutase. J Virol (2004) 0.86
Comparative analysis of the complete genome sequence of the California MSW strain of myxoma virus reveals potential host adaptations. J Virol (2013) 0.85
Genome sequence of SG33 strain and recombination between wild-type and vaccine myxoma viruses. Emerg Infect Dis (2011) 0.85
Identification of a new rhoptry neck complex RON9/RON10 in the Apicomplexa parasite Toxoplasma gondii. PLoS One (2012) 0.83
Myxoma Virus Induces Ligand Independent Extrinsic Apoptosis in Human Myeloma Cells. Clin Lymphoma Myeloma Leuk (2015) 0.83
Poxviral ankyrin proteins. Viruses (2015) 0.82
Innate immune response of human plasmacytoid dendritic cells to poxvirus infection is subverted by vaccinia E3 via its Z-DNA/RNA binding domain. PLoS One (2012) 0.82
ONCOLYTIC HERPES SIMPLEX VIRUS 1 (HSV-1) VECTORS: INCREASING TREATMENT EFFICACY AND RANGE THROUGH STRATEGIC VIRUS DESIGN. Drugs Future (2010) 0.82
A whole-genome RNA interference screen for human cell factors affecting myxoma virus replication. J Virol (2013) 0.81
An overview of the lagomorph immune system and its genetic diversity. Immunogenetics (2015) 0.81
Viral serpin therapeutics from concept to clinic. Methods Enzymol (2011) 0.80
Tumorigenic poxviruses up-regulate intracellular superoxide to inhibit apoptosis and promote cell proliferation. J Virol (2005) 0.80
Evasion of the Innate Immune Type I Interferon System by Monkeypox Virus. J Virol (2015) 0.80
Myxoma virus expressing human interleukin-12 does not induce myxomatosis in European rabbits. J Virol (2007) 0.80
Prediction of steps in the evolution of variola virus host range. PLoS One (2014) 0.80
Genomic and phenotypic characterization of myxoma virus from Great Britain reveals multiple evolutionary pathways distinct from those in Australia. PLoS Pathog (2017) 0.78
Molecular characterisation of virulence graded field isolates of myxoma virus. Virol J (2010) 0.77
Differential susceptibility of human cancer cell lines to wild-type tanapoxvirus infection. Open Virol J (2010) 0.77
Detection of myxoma viruses encoding a defective M135R gene from clinical cases of myxomatosis; possible implications for the role of the M135R protein as a virulence factor. Virol J (2010) 0.77
Genetic Variability of Myxoma Virus Genomes. J Virol (2016) 0.76
The megavirus chilensis Cu,Zn-superoxide dismutase: the first viral structure of a typical cellular copper chaperone-independent hyperstable dimeric enzyme. J Virol (2014) 0.76
Production of Myxoma virus gateway entry and expression libraries and validation of viral protein expression. Curr Protoc Microbiol (2011) 0.75
A new insight into viral proteins as Immunomodulatory therapeutic agents: KSHV vOX2 a homolog of human CD200 as a potent anti-inflammatory protein. Iran J Basic Med Sci (2016) 0.75
Monkeypox virus induces the synthesis of less dsRNA than vaccinia virus, and is more resistant to the anti-poxvirus drug, IBT, than vaccinia virus. Virology (2016) 0.75
M011L-deficient oncolytic myxoma virus induces apoptosis in brain tumor-initiating cells and enhances survival in a novel immunocompetent mouse model of glioblastoma. Neuro Oncol (2016) 0.75
The inflammasome as a target of modulation by DNA viruses. Future Virol (2013) 0.75
Reverse engineering field isolates of myxoma virus demonstrates that some gene disruptions or loss of function do not explain virulence changes observed in the field. J Virol (2017) 0.75
The sequence of the human genome. Science (2001) 101.55
A whole-genome assembly of Drosophila. Science (2000) 38.48
B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med (1999) 16.91
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46
Treatment of dysthymia and minor depression in primary care: A randomized controlled trial in older adults. JAMA (2000) 8.15
Association between hospital and surgeon procedure volume and outcomes of total hip replacement in the United States medicare population. J Bone Joint Surg Am (2001) 7.67
The genome of the natural genetic engineer Agrobacterium tumefaciens C58. Science (2001) 6.90
Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. Proc Natl Acad Sci U S A (1994) 5.74
Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta. EMBO J (1999) 5.49
Racial differences in the incidence of cardiac arrest and subsequent survival. The CPR Chicago Project. N Engl J Med (1993) 4.97
NF-AT components define a family of transcription factors targeted in T-cell activation. Nature (1994) 4.90
The Human Connectome Project: a data acquisition perspective. Neuroimage (2012) 4.64
An amino-terminal c-myc domain required for neoplastic transformation activates transcription. Mol Cell Biol (1990) 4.24
Apoptosis: a mechanism of cell killing by influenza A and B viruses. J Virol (1994) 4.20
B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production. Nat Immunol (2001) 4.10
A transcriptional hierarchy involved in mammalian cell-type specification. Nature (1992) 4.08
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors. Nat Med (1997) 3.89
A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal. Proc Natl Acad Sci U S A (1996) 3.89
Recent expansion of Toxoplasma through enhanced oral transmission. Science (2003) 3.88
Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB. Neuron (1990) 3.70
Rad23 links DNA repair to the ubiquitin/proteasome pathway. Nature (1998) 3.54
Complete genomic sequence and analysis of the prion protein gene region from three mammalian species. Genome Res (1998) 3.44
Establishment and characterization of a cell line of human breast carcinoma origin. Eur J Cancer (1979) 3.37
Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature. Cell (2001) 3.37
Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse. Dev Cell (2001) 3.30
Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. Alzheimer's Disease Centers Consortium on Apolipoprotein E and Alzheimer's Disease. N Engl J Med (1998) 3.23
TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage. J Cell Biol (2001) 3.22
The crystal structure of HaeIII methyltransferase convalently complexed to DNA: an extrahelical cytosine and rearranged base pairing. Cell (1995) 3.17
Sensitivity and positive predictive value of Medicare Part B physician claims for rheumatologic diagnoses and procedures. Arthritis Rheum (1997) 2.93
Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation. Proc Natl Acad Sci U S A (2001) 2.93
Efficacy of meningococcal vaccine and barriers to vaccination. JAMA (1998) 2.92
Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes. Proc Natl Acad Sci U S A (1994) 2.91
Smoking and mortality among older men and women in three communities. N Engl J Med (1991) 2.86
CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex. Proc Natl Acad Sci U S A (1999) 2.81
Outcome of CPR in a large metropolitan area--where are the survivors? Ann Emerg Med (1991) 2.76
Uterine papillary serous and clear cell carcinomas predict for poorer survival compared to grade 3 endometrioid corpus cancers. Br J Cancer (2006) 2.67
ATP is essential for protein translocation into Escherichia coli membrane vesicles. Proc Natl Acad Sci U S A (1985) 2.65
Internal validation of Medicare claims data. Epidemiology (1994) 2.62
Mutation of the Bacillus subtilis alkyl hydroperoxide reductase (ahpCF) operon reveals compensatory interactions among hydrogen peroxide stress genes. J Bacteriol (1996) 2.57
Minor groove RNA triplex in the crystal structure of a ribosomal frameshifting viral pseudoknot. Nat Struct Biol (1999) 2.57
A prospective 4-year follow-up study of attention-deficit hyperactivity and related disorders. Arch Gen Psychiatry (1996) 2.55
Impact of education for physicians on patient outcomes. Pediatrics (1998) 2.54
Is maternal smoking during pregnancy a risk factor for attention deficit hyperactivity disorder in children? Am J Psychiatry (1996) 2.54
Risk and benefit. Nature (1998) 2.51
The King-Devick test as a determinant of head trauma and concussion in boxers and MMA fighters. Neurology (2011) 2.51
Repetitive transcranial magnetic stimulation of the human prefrontal cortex induces dopamine release in the caudate nucleus. J Neurosci (2001) 2.49
Uptake of screening and prevention in women at very high risk of breast cancer. Lancet (2001) 2.45
Xa21D encodes a receptor-like molecule with a leucine-rich repeat domain that determines race-specific recognition and is subject to adaptive evolution. Plant Cell (1998) 2.43
Comparison of open and laparoscopic live donor nephrectomy. Ann Surg (1997) 2.43
A homeodomain protein related to caudal regulates intestine-specific gene transcription. Mol Cell Biol (1994) 2.42
A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4. Proc Natl Acad Sci U S A (2001) 2.42
Pharmacologic doses of granulocyte colony-stimulating factor affect cytokine production by lymphocytes in vitro and in vivo. Blood (2000) 2.42
SecA protein is required for secretory protein translocation into E. coli membrane vesicles. Cell (1988) 2.41
Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences. Mol Cell Biol (1988) 2.40
A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability. Oncogene (1998) 2.39
Solution structure of a bovine immunodeficiency virus Tat-TAR peptide-RNA complex. Science (1995) 2.35
Nephrotic syndrome: an under-recognised immune-mediated complication of non-myeloablative allogeneic haematopoietic cell transplantation. Br J Haematol (2005) 2.32
Primitive deuterostomes from the Chengjiang Lagerstätte (Lower Cambrian, China). Nature (2001) 2.31
Seventh cervical nerve root transfer from the contralateral healthy side for treatment of brachial plexus root avulsion. J Hand Surg Br (1992) 2.30
LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response. J Immunol (2000) 2.27
SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function. Mol Cell Biol (2000) 2.27
Survival time comparison between Hawley and clear overlay retainers: a randomized trial. J Dent Res (2011) 2.26
Predictors of persistence and remission of ADHD into adolescence: results from a four-year prospective follow-up study. J Am Acad Child Adolesc Psychiatry (1996) 2.24
Basic epidemiology of fractures of the upper and lower limb among Americans over 65 years of age. Epidemiology (1996) 2.23
Takling the 'hideous scourge': the creation of the venereal disease treatment centres in early twentieth-century Britain. Soc Hist Med (1992) 2.20
Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway. Nat Med (2000) 2.18
Surveillance of the first case of human avian influenza A (H7N9) virus in Beijing, China. Infection (2013) 2.18
Reconstituted nuclei depleted of a vertebrate GLFG nuclear pore protein, p97, import but are defective in nuclear growth and replication. J Cell Biol (1995) 2.11
NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies. Cell Immunol (1998) 2.11
The delirium symptom interview: an interview for the detection of delirium symptoms in hospitalized patients. J Geriatr Psychiatry Neurol (1992) 2.11
Partial caries removal and cariostatic materials in carious primary molar teeth: a randomised controlled clinical trial. Br Dent J (2004) 2.10
Effect of ADP and ionic strength on the kinetic and motile properties of recombinant mouse myosin V. J Biol Chem (2000) 2.09
Biogenesis of vaccinia: isolation of conditional lethal mutants and electron microscopic characterization of their phenotypically expressed defects. Virology (1978) 2.09
ADHD is associated with early initiation of cigarette smoking in children and adolescents. J Am Acad Child Adolesc Psychiatry (1997) 2.09
General anaesthesia: who decides, and why? Br Dent J (1994) 2.08
The DNA repair protein rad23 is a negative regulator of multi-ubiquitin chain assembly. Nat Cell Biol (2000) 2.07
Encoding of a homolog of the IFN-gamma receptor by myxoma virus. Science (1992) 2.07
RNA recognition by an isolated alpha helix. Cell (1993) 2.05
PPARalpha agonist fenofibrate improves diabetic nephropathy in db/db mice. Kidney Int (2006) 2.05
Rapid angiographic progression of coronary artery disease in patients with angina pectoris. The role of complex stenosis morphology. Circulation (1995) 2.04
Safety, tolerance, and pharmacokinetics of high-dose liposomal amphotericin B (AmBisome) in patients infected with Aspergillus species and other filamentous fungi: maximum tolerated dose study. Antimicrob Agents Chemother (2001) 2.03
MDM2 suppresses p73 function without promoting p73 degradation. Mol Cell Biol (1999) 2.00
Ineffective esophageal motility (IEM): the primary finding in patients with nonspecific esophageal motility disorder. Dig Dis Sci (1997) 1.99
Acute health effects of the Sea Empress oil spill. J Epidemiol Community Health (1999) 1.99
Epitope mapping of human anti-adeno-associated virus type 2 neutralizing antibodies: implications for gene therapy and virus structure. J Virol (2000) 1.98
Chinese Hemophilia Joint Health Score 2.1 reliability study. Haemophilia (2013) 1.98
Antigenic cancer cells grow progressively in immune hosts without evidence for T cell exhaustion or systemic anergy. J Exp Med (1997) 1.96
The epidemiology of diagnosed pulmonary embolism and deep venous thrombosis in the elderly. Arch Intern Med (1994) 1.96
Epidemiological characteristics of diabetes mellitus and impaired glucose regulation in a Chinese adult population: the Shanghai Diabetes Studies, a cross-sectional 3-year follow-up study in Shanghai urban communities. Diabetologia (2006) 1.96
A novel interactive electronic protocol review system. Contemp Top Lab Anim Sci (2001) 1.94
Role of RNA structure in arginine recognition of TAR RNA. Proc Natl Acad Sci U S A (1993) 1.94
Nuclear texture measurements in image cytometry. Pathologica (1995) 1.94
The prevalence and nature of recent self-reported changes in general dental practice in a sample of English general dental practitioners. Br Dent J (2004) 1.93
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Res (2013) 1.92
Nucleotide sequence of a multiple-copy gene for the B protein of photosystem II of a cyanobacterium. Proc Natl Acad Sci U S A (1984) 1.92
Can rabies be eradicated? Dev Biol (Basel) (2008) 1.91
LIPSIA--a new software system for the evaluation of functional magnetic resonance images of the human brain. Comput Med Imaging Graph (2001) 1.90
The impact of passive smoking on emergency room visits of urban children with asthma. Am Rev Respir Dis (1987) 1.89