Published in J Biol Chem on November 08, 1996
Activation of inflammation/NF-kappaB signaling in infants born to arsenic-exposed mothers. PLoS Genet (2007) 2.19
NF-kappaB/Egr-1/Gadd45 are sequentially activated upon UVB irradiation to mediate epidermal cell death. EMBO J (2004) 1.55
Early growth response factor-1 induction by injury is triggered by release and paracrine activation by fibroblast growth factor-2. Am J Pathol (1999) 1.10
Vascular smooth muscle cell proliferation and regrowth after mechanical injury in vitro are Egr-1/NGFI-A-dependent. Am J Pathol (1999) 1.02
Divergent transforming growth factor-beta signaling in hepatic stellate cells after liver injury: functional effects on ECE-1 regulation. Am J Pathol (2008) 0.88
Similar morphological and molecular signatures shared by female and male germline stem cells. Sci Rep (2014) 0.82
Loss of transcription factor early growth response gene 1 results in impaired endochondral bone repair. Bone (2011) 0.80
An Arf-Egr-C/EBPβ pathway linked to ras-induced senescence and cancer. Mol Cell Biol (2014) 0.77
EGR-1/Bax pathway plays a role in vitamin E δ-tocotrienol-induced apoptosis in pancreatic cancer cells. J Nutr Biochem (2015) 0.77
Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents. Nature (2001) 4.28
Early growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors. Prog Nucleic Acid Res Mol Biol (1995) 3.35
Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2. Proc Natl Acad Sci U S A (1997) 3.06
Transcriptional repression mediated by the WT1 Wilms tumor gene product. Science (1991) 3.06
The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity. Mol Cell Biol (1997) 2.76
Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structure. Proc Natl Acad Sci U S A (1988) 2.73
pH regulation in single glomerular mesangial cells. I. Acid extrusion in absence and presence of HCO3-. Am J Physiol (1988) 2.71
Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature (1995) 2.61
A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1. Mol Cell Biol (1993) 2.61
Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1. Science (1992) 2.50
Endostatin induces endothelial cell apoptosis. J Biol Chem (1999) 2.49
Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals. Mol Cell Biol (1990) 2.41
Combined effects of angiostatin and ionizing radiation in antitumour therapy. Nature (1998) 2.29
Wild-type p53 and v-Src exert opposing influences on human vascular endothelial growth factor gene expression. Cancer Res (1995) 2.23
Decrease of blood pressure by ventrolateral medullary decompression in essential hypertension. Lancet (1998) 2.21
Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements. Mol Cell Biol (1990) 2.16
Specific association of the gene product of PKD2 with the TRPC1 channel. Proc Natl Acad Sci U S A (1999) 2.09
Anti-angiogenic cues from vascular basement membrane collagen. Cancer Res (2000) 2.06
EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors. Oncogene (1991) 2.01
Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth. J Biol Chem (2000) 1.97
Stimulation of rat mesangial cell proliferation by macrophage interleukin 1. J Immunol (1983) 1.94
Neutral proteinase activity produced in vitro by cells of the glomerular mesangium. Kidney Int (1983) 1.81
Transforming growth factor alpha is a target for the von Hippel-Lindau tumor suppressor. Cancer Res (1998) 1.71
Cell renewal of glomerular cell types in normal rats. An autoradiographic analysis. Kidney Int (1983) 1.71
Arginine vasopressin enhances pHi regulation in the presence of HCO3- by stimulating three acid-base transport systems. Nature (1989) 1.69
Nucleotide sequence of a cDNA encoding TIS11, a message induced in Swiss 3T3 cells by the tumor promoter tetradecanoyl phorbol acetate. Oncogene (1989) 1.60
Expression and function of the leucine zipper protein Par-4 in apoptosis. Mol Cell Biol (1997) 1.59
A thymocyte-activating factor derived from glomerular mesangial cells. J Immunol (1983) 1.59
Gene for the human T cell differentiation antigen Leu-2/T8 is closely linked to the kappa light chain locus on chromosome 2. J Exp Med (1985) 1.59
Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product. Proc Natl Acad Sci U S A (1993) 1.59
5' flanking sequence and genomic structure of Egr-1, a murine mitogen inducible zinc finger encoding gene. Nucleic Acids Res (1988) 1.57
pH regulation in single glomerular mesangial cells. II. Na+-dependent and -independent Cl(-)-HCO3- exchangers. Am J Physiol (1988) 1.51
Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1. Proc Natl Acad Sci U S A (1992) 1.51
Cell surface glypicans are low-affinity endostatin receptors. Mol Cell (2001) 1.51
Isolation of the gene encoding the human T-lymphocyte differentiation antigen Leu-2 (T8) by gene transfer and cDNA subtraction. Proc Natl Acad Sci U S A (1984) 1.47
Antiangiogenic activity of restin, NC10 domain of human collagen XV: comparison to endostatin. Biochem Biophys Res Commun (1999) 1.46
Endostatin: yeast production, mutants, and antitumor effect in renal cell carcinoma. Cancer Res (1999) 1.45
Characterization of the zinc finger protein encoded by the WT1 Wilms' tumor locus. Oncogene (1991) 1.40
Early growth response-1-dependent apoptosis is mediated by p53. J Biol Chem (1997) 1.40
Decreased expression of the pro-apoptotic protein Par-4 in renal cell carcinoma. Oncogene (1999) 1.38
Cell culture approaches to the analysis of glomerular inflammation. Kidney Int (1986) 1.37
Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN. Proc Natl Acad Sci U S A (1991) 1.36
Interleukin 6 is an autocrine growth factor for mesangial cells. Kidney Int (1990) 1.36
The T cell differentiation antigen Leu-2/T8 is homologous to immunoglobulin and T cell receptor variable regions. Cell (1985) 1.35
Expression of two "immediate early" genes, Egr-1 and c-fos, in response to renal ischemia and during compensatory renal hypertrophy in mice. J Clin Invest (1990) 1.35
Expression patterns of immediate early transcription factors in human non-small cell lung cancer. The Lung Cancer Study Group. Oncogene (1995) 1.34
Synergy between angiostatin and endostatin: inhibition of ovarian cancer growth. Cancer Res (2000) 1.34
Interleukin 1 and the glomerular mesangium. I. Purification and characterization of a mesangial cell-derived autogrowth factor. J Immunol (1986) 1.34
Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation. Proc Natl Acad Sci U S A (1993) 1.32
Cloning, expression, and in vitro activity of human endostatin. Biochem Biophys Res Commun (1999) 1.28
Extracellular ATP causes apoptosis and necrosis of cultured mesangial cells via P2Z/P2X7 receptors. Am J Physiol (1998) 1.28
Repression of the transforming growth factor-beta 1 gene by the Wilms' tumor suppressor WT1 gene product. Mol Endocrinol (1994) 1.27
The temporal relationship between glomerular cell proliferation and monocyte infiltration in experimental glomerulonephritis. Virchows Arch B Cell Pathol Incl Mol Pathol (1982) 1.21
Transforming growth factor beta1 is a target for the von Hippel-Lindau tumor suppressor and a critical growth factor for clear cell renal carcinoma. Cancer Res (1999) 1.21
DNA recognition by splicing variants of the Wilms' tumor suppressor, WT1. Mol Cell Biol (1994) 1.20
Differential expression of a zinc finger-encoding gene in response to positive versus negative signaling through receptor immunoglobulin in murine B lymphocytes. Mol Cell Biol (1989) 1.20
Expression of the early growth response 1 and 2 zinc finger genes during induction of monocytic differentiation. J Clin Invest (1991) 1.18
Fibrosis and angiogenesis. Curr Opin Nephrol Hypertens (2000) 1.18
Formation of extracellular matrix by cultured rat mesangial cells. Am J Pathol (1989) 1.18
Spontaneous expression of immediately-early response genes c-fos and egr-1 in collagenase-producing rheumatoid synovial fibroblasts. Rheumatol Int (1992) 1.17
The pathobiology of the mesangium. Kidney Int (1992) 1.17
Mesangial cell hillocks. Nodular foci of exaggerated growth of cells and matrix in prolonged culture. Am J Pathol (1986) 1.16
v-Src activates mitogen-responsive transcription factor Egr-1 via serum response elements. J Biol Chem (1991) 1.15
Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin. Cancer Res (1998) 1.13
GP-2/THP gene family encodes self-binding glycosylphosphatidylinositol-anchored proteins in apical secretory compartments of pancreas and kidney. Proc Natl Acad Sci U S A (1992) 1.13
The Wilms' tumor suppressor gene WT1 is negatively autoregulated. J Biol Chem (1994) 1.11
Egr-1 expression in surface Ig-mediated B cell activation. Kinetics and association with protein kinase C activation. J Immunol (1990) 1.10
Developmental expression of the putative transcription factor Egr-1 suggests that Egr-1 and c-fos are coregulated in some tissues. Development (1990) 1.09
Gene therapy targeted by radiation preferentially radiosensitizes tumor cells. Cancer Res (1994) 1.09
Rapid induction and translocation of Egr-1 in response to mechanical strain in vascular smooth muscle cells. Circ Res (1999) 1.09
Interaction between RGS7 and polycystin. Proc Natl Acad Sci U S A (1999) 1.09
Regulation of the Egr-1 gene by tumor necrosis factor and interferons in primary human fibroblasts. J Biol Chem (1992) 1.09
Egr-1, a serum-inducible zinc finger protein, regulates transcription of the rat cardiac alpha-myosin heavy chain gene. J Biol Chem (1991) 1.07
Alpha8 integrin in glomerular mesangial cells and in experimental glomerulonephritis. Kidney Int (1999) 1.07
Synthesis and processing of cathepsin L, an elastase, by human alveolar macrophages. Biochem J (1989) 1.07
Sp1 is a critical regulator of the Wilms' tumor-1 gene. J Biol Chem (1997) 1.07
Regulation of mesangial cell proliferation. Kidney Int (1999) 1.07
Methylation of an immediate-early inducible gene as a mechanism for B cell tolerance induction. Science (1990) 1.06
The mesangium and glomerulonephritis. Klin Wochenschr (1982) 1.04
Antitumor interaction of short-course endostatin and ionizing radiation. Cancer J (2001) 1.04
Enhancement of glomerular mesangial cell neutral proteinase secretion by macrophages: role of interleukin 1. J Immunol (1986) 1.04
Extracellular ATP stimulates proliferation of cultured mesangial cells via P2-purinergic receptors. Am J Physiol (1992) 1.02
Complete nucleotide and deduced amino acid sequences of human and murine preprocathepsin L. An abundant transcript induced by transformation of fibroblasts. J Clin Invest (1988) 1.02
Nitric oxide synthase isoforms and glomerular hyperfiltration in early diabetic nephropathy. J Am Soc Nephrol (2000) 1.01
Induction of immediate-early genes by angiotensin II and endothelin-1 in adult rat cardiomyocytes. J Hypertens (1993) 1.01
Antineutrophil cytoplasmic antibodies induce human monocytes to produce oxygen radicals in vitro. Arthritis Rheum (2001) 1.00
Localization of the protein product of the immediate early growth response gene, Egr-1, in the kidney after ischemia and reperfusion. Cell Regul (1991) 0.99
The serum and TPA responsive promoter and intron-exon structure of EGR2, a human early growth response gene encoding a zinc finger protein. Nucleic Acids Res (1990) 0.99
Angiotensin-induced hypertension in the rat. Sympathetic nerve activity and prostaglandins. Hypertension (1989) 0.98
Progressive glomerular sclerosis in experimental antiglomerular basement membrane glomerulonephritis. Am J Kidney Dis (1986) 0.98
Transforming growth factor-beta in renal disease. Kidney Blood Press Res (1998) 0.98
Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud. Proc Natl Acad Sci U S A (2001) 0.98
Activation of vitamin D receptor by the Wilms' tumor gene product mediates apoptosis of renal cells. J Am Soc Nephrol (2001) 0.97
Lipopolysaccharide induces Egr-1 mRNA and protein in murine peritoneal macrophages. J Immunol (1992) 0.96