Published in Nutr Cancer on January 01, 1996
The hairless mouse in skin research. J Dermatol Sci (2008) 1.95
Induction of cyclin D1 overexpression by activated ras. Oncogene (1994) 2.35
Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment. Proc Natl Acad Sci U S A (1998) 2.10
Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis. Mol Carcinog (1999) 1.95
Studies on the mechanism of skin tumor promotion: evidence for several stages in promotion. Proc Natl Acad Sci U S A (1980) 1.94
Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo. Genes Dev (1998) 1.88
VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development. Oncogene (1998) 1.61
Detection of loss of heterozygosity in formalin-fixed paraffin-embedded tumor specimens by the polymerase chain reaction. Am J Pathol (1991) 1.59
High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC. Nature (1995) 1.57
p53 protein accumulation and gene mutation in the progression of human prostate carcinoma. J Natl Cancer Inst (1993) 1.54
Expression of cyclin D1 in epithelial tissues of transgenic mice results in epidermal hyperproliferation and severe thymic hyperplasia. Proc Natl Acad Sci U S A (1996) 1.51
Evidence that the centrally and peripherally located cells in the murine epidermal proliferative unit are two distinct cell populations. J Invest Dermatol (1985) 1.47
Studies on mechanism of action of anti-tumor-promoting agents: their specificity in two-stage promotion. Proc Natl Acad Sci U S A (1980) 1.47
p53 mutations in prostate cancer bone metastases suggest that selected p53 mutants in the primary site define foci with metastatic potential. J Urol (1999) 1.46
15-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells. J Natl Cancer Inst (2000) 1.43
Inhibition of peroxisome-proliferator-activated receptor (PPAR)alpha by MK886. Biochem J (2001) 1.42
Evidence that a slowly cycling subpopulation of adult murine epidermal cells retains carcinogen. Cancer Res (1986) 1.41
Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53. Proc Natl Acad Sci U S A (1998) 1.38
Frequent loss of heterozygosity in human primary squamous cell and colon carcinomas at 7q31.1: evidence for a broad range tumor suppressor gene. Cancer Res (1995) 1.36
15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. Cancer Res (2000) 1.31
E2F1 has both oncogenic and tumor-suppressive properties in a transgenic model. Mol Cell Biol (1999) 1.29
Mutational and functional analyses reveal that ST7 is a highly conserved tumor-suppressor gene on human chromosome 7q31. Nat Genet (2001) 1.28
Oxidative metabolism of linoleic acid modulates PPAR-beta/delta suppression of PPAR-gamma activity. Oncogene (2006) 1.26
Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development. Oncogene (1998) 1.25
Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells. Regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues. J Biol Chem (1998) 1.24
(C-A)n microsatellite repeat D7S522 is the most commonly deleted region in human primary breast cancer. Proc Natl Acad Sci U S A (1994) 1.24
Loss of heterozygosity in human primary prostate carcinomas: a possible tumor suppressor gene at 7q31.1. Cancer Res (1994) 1.23
Mechanism-based cancer prevention approaches: targets, examples, and the use of transgenic mice. J Natl Cancer Inst (1999) 1.23
Nonsteroidal anti-inflammatory drugs induce apoptosis in esophageal cancer cells by restoring 15-lipoxygenase-1 expression. Cancer Res (2001) 1.22
Overexpression of cyclin D1 in mouse skin carcinogenesis. Oncogene (1993) 1.22
Nonrandom duplication of the chromosome bearing a mutated Ha-ras-1 allele in mouse skin tumors. Proc Natl Acad Sci U S A (1990) 1.20
Progressive dysplasia and aneuploidy are hallmarks of mouse skin papillomas: relevance to malignancy. Proc Natl Acad Sci U S A (1987) 1.19
Expression of G1 cyclins, cyclin-dependent kinases, and cyclin-dependent kinase inhibitors in androgen-induced prostate proliferation in castrated rats. Cell Growth Differ (1996) 1.15
Early overexpression of cyclin D1 protein in mouse skin carcinogenesis. Carcinogenesis (1995) 1.14
Overexpression of the prostaglandin E2 receptor EP2 results in enhanced skin tumor development. Oncogene (2006) 1.13
Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels. Cancer Res (1996) 1.13
ras activity and cyclin D1 expression: an essential mechanism of mouse skin tumor development. Mol Carcinog (1999) 1.12
A variant of pulmonary alveolar microlithiasis in nackt mice. Vet Pathol (2002) 1.11
Recognition of mycobacterial antigens by sera from patients with leprosy. J Clin Microbiol (1988) 1.08
Studies on the mechanisms involved in multistage carcinogenesis in mouse skin. J Cell Biochem (1982) 1.07
Sequential trisomization of chromosomes 6 and 7 in mouse skin premalignant lesions. Mol Carcinog (1989) 1.06
Aneuploidy, an early event in mouse skin tumor development. Carcinogenesis (1986) 1.06
Increased cell growth and tumorigenicity in human prostate LNCaP cells by overexpression to cyclin D1. Oncogene (1998) 1.06
Transgenic expression of cyclin-dependent kinase 4 results in epidermal hyperplasia, hypertrophy, and severe dermal fibrosis. Am J Pathol (2001) 1.05
Allelic loss at 7q31.1 in human primary ovarian carcinomas suggests the existence of a tumor suppressor gene. Oncogene (1995) 1.05
Increased expression of mutated Ha-ras during premalignant progression in SENCAR mouse skin. Mol Carcinog (1999) 1.05
Deregulated expression of cell-cycle proteins during premalignant progression in SENCAR mouse skin. Oncogene (1998) 1.05
Angiogenesis is an early event in the development of chemically induced skin tumors. Carcinogenesis (1998) 1.04
Cyclin D2 overexpression in transgenic mice induces thymic and epidermal hyperplasia whereas cyclin D3 expression results only in epidermal hyperplasia. Am J Pathol (2000) 1.04
Separation of epidermal cells by density centrifugation: a new technique for studies on normal and pathological differentiation. J Cutan Pathol (1982) 1.03
Prostaglandin E(2) regulation of cyclooxygenase expression in keratinocytes is mediated via cyclic nucleotide-linked prostaglandin receptors. J Lipid Res (2000) 1.03
A direct cytogenetic technique for mouse skin carcinomas and papillomas. Cancer Genet Cytogenet (1986) 1.03
Multistage chemical carcinogenesis protocols produce spindle cell carcinomas of the mouse skin. Carcinogenesis (1989) 1.02
Alterations of the p53 tumor suppressor gene during mouse skin tumor progression. Cancer Res (1991) 1.02
Terminal differentiation-resistant epidermal cells in mice undergoing two-stage carcinogenesis. Cancer Res (1987) 1.01
Elevated expression and point mutation of the Ha-ras proto-oncogene in mouse skin tumors promoted by benzoyl peroxide and other promoting agents. Carcinogenesis (1987) 1.01
Subpopulations of primary adult murine epidermal basal cells sedimented on density gradients. Cell Tissue Kinet (1990) 1.00
The role of the EP receptors for prostaglandin E2 in skin and skin cancer. Cancer Metastasis Rev (2011) 0.99
Cyclin D1 overexpression in mouse epidermis increases cyclin-dependent kinase activity and cell proliferation in vivo but does not affect skin tumor development. Cell Growth Differ (1999) 0.99
Myc lacks E2F1's ability to suppress skin carcinogenesis. Oncogene (2001) 0.98
Alterations of p53, cyclin D1, Rb, and H-ras in human oral carcinomas related to tobacco use. Cancer (1998) 0.98
Coordinated changes in cell cycle machinery occur during keratinocyte terminal differentiation. Oncogene (1999) 0.97
Distribution of conjugated linoleic acid and metabolites in different lipid fractions in the rat liver. J Lipid Res (2001) 0.97
p53, Rb, and cyclin D1 expression in human oral verrucous carcinomas. Cancer (1996) 0.97
Synchronized proliferation induced by 12-O-tetradecanoylphorbol-13-acetate treatment of mouse skin: an in vivo model for cell cycle regulation. Cell Growth Differ (1998) 0.97
IKKα represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the skin. Cell Death Differ (2011) 0.96
Inhibition of tumorigenicity of a murine squamous cell carcinoma (SCC) cell line by a putative tumor suppressor gene on human chromosome 7. Oncogene (1994) 0.96
The effect of vitamin E acetate on ultraviolet-induced mouse skin carcinogenesis. Mol Carcinog (1998) 0.96
Transgenic expression of cyclin D1 in thymic epithelial precursors promotes epithelial and T cell development. J Immunol (2000) 0.96
Rapid detection of xenotransplanted human tissues using in situ hybridization. Am J Pathol (1986) 0.96
Aberrant expression of the simple epithelial type II keratin 8 by mouse skin carcinomas but not papillomas. Mol Carcinog (1992) 0.96
Strain differences and solvent effects in mouse skin carcinogenesis experiments using carcinogens, tumor initiators and promoters. Prog Exp Tumor Res (1983) 0.95
Definitive functional evidence for a tumor suppressor gene on human chromosome 7q31.1 neighboring the Fra7G site. Oncogene (2000) 0.95
Epidermal proliferation but not quantity of DNA photodamage is correlated with UV-induced mouse skin carcinogenesis. J Invest Dermatol (1997) 0.93
Activators of peroxisome proliferator-activated receptor-alpha partially inhibit mouse skin tumor promotion. Mol Carcinog (2000) 0.93
8S-lipoxygenase products activate peroxisome proliferator-activated receptor alpha and induce differentiation in murine keratinocytes. Cell Growth Differ (2000) 0.92
Regulation of the differentiation-related gene Drg-1 during mouse skin carcinogenesis. Mol Carcinog (2001) 0.92
During development, 17alpha-estradiol is a potent estrogen and carcinogen. Environ Health Perspect (1997) 0.92
Effects of anti-promoters and strain of mouse on tumor promoter-induced oxidants in murine epidermal cells. Carcinogenesis (1986) 0.91
Sequential development of aneuploidy, keratin modifications, and gamma-glutamyltransferase expression in mouse skin papillomas. Cancer Res (1988) 0.91
Differential effects of estradiol-17 beta and progesterone on the proliferation of glandular and luminal cells of rabbit uterine epithelium. Biol Reprod (1981) 0.90
Mitochondrial respiratory uncoupling promotes keratinocyte differentiation and blocks skin carcinogenesis. Oncogene (2012) 0.90
Cytogenetic, molecular and functional evidence for novel tumor suppressor genes on the long arm of human chromosome 7. Mol Carcinog (1996) 0.90
Quantitation of primary in vitro clonogenic keratinocytes from normal adult murine epidermis, following initiation, and during promotion of epidermal tumors. Cancer Res (1988) 0.89
Suppression of tumor promoter-induced chemiluminescence in mouse epidermal cells by several inhibitors of arachidonic acid metabolism. Cancer Res (1985) 0.89
Overlapping loss of heterozygosity by mitotic recombination on mouse chromosome 7F1-ter in skin carcinogenesis. Proc Natl Acad Sci U S A (1991) 0.89
Transgenic expression of E2F3a causes DNA damage leading to ATM-dependent apoptosis. Oncogene (2008) 0.88
Characterization of skin tumor promotion and progression by chrysarobin in SENCAR mice. Cancer Res (1987) 0.87
Estrogen and progesterone regulation of proliferation, migration, and loss in different target cells of rabbit uterine epithelium. Endocrinology (1984) 0.87
Highly sensitive C-reactive protein and male gender are independently related to the severity of coronary disease in patients with metabolic syndrome and an acute coronary event. Braz J Med Biol Res (2010) 0.87
Alterations in the expression of uvomorulin and Na+,K(+)-adenosine triphosphatase during mouse skin tumor progression. Am J Pathol (1992) 0.87
Temporal relationship between rabbit uterine epithelium proliferation and uteroglobin production. Biol Reprod (1981) 0.87
Interleukin-1 alpha mediates phorbol ester-induced inflammation and epidermal hyperplasia. FASEB J (1994) 0.87
Estrogen and progesterone regulation of proliferation and differentiation of rabbit uterine epithelium. Prog Clin Biol Res (1984) 0.87
Beta2 integrin/ICAM-1 adhesion molecule interactions in cutaneous inflammation and tumor promotion. Carcinogenesis (1998) 0.86