Published in Br J Pharmacol on December 01, 1996
Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia. Pharmacol Ther (2009) 1.67
The histamine H3 receptor: an attractive target for the treatment of cognitive disorders. Br J Pharmacol (2008) 1.49
Psychopharmacological approaches to modulating attention in the five-choice serial reaction time task: implications for schizophrenia. Psychopharmacology (Berl) (2004) 1.22
Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice. Proc Natl Acad Sci U S A (2006) 1.22
Histamine in the regulation of wakefulness. Sleep Med Rev (2010) 1.05
Tuning shifts of the auditory system by corticocortical and corticofugal projections and conditioning. Neurosci Biobehav Rev (2011) 0.96
Activation of peripheral and spinal histamine H3 receptors inhibits formalin-induced inflammation and nociception, respectively. Pharmacol Biochem Behav (2007) 0.96
Targeted disruption of H3 receptors results in changes in brain histamine tone leading to an obese phenotype. J Clin Invest (2002) 0.94
Histaminergic mechanisms for modulation of memory systems. Neural Plast (2011) 0.94
Regional differential effects of the novel histamine H3 receptor antagonist 6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methyl-3-pyridinecarboxamide hydrochloride (GSK189254) on histamine release in the central nervous system of freely moving rats. J Pharmacol Exp Ther (2009) 0.90
Differential effects of acute and repeat dosing with the H3 antagonist GSK189254 on the sleep-wake cycle and narcoleptic episodes in Ox-/- mice. Br J Pharmacol (2009) 0.88
International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors. Pharmacol Rev (2015) 0.88
Anxiolytic-like profiles of histamine H3 receptor agonists in animal models of anxiety: a comparative study with antidepressants and benzodiazepine anxiolytic. Psychopharmacology (Berl) (2009) 0.87
Characterization of histamine H3 receptors in Alzheimer's Disease brain and amyloid over-expressing TASTPM mice. Br J Pharmacol (2009) 0.86
Histamine H₃ receptors, the complex interaction with dopamine and its implications for addiction. Br J Pharmacol (2013) 0.85
Effects of the H(3) antagonist, thioperamide, on behavioral alterations induced by systemic MK-801 administration in rats. Psychopharmacology (Berl) (2009) 0.81
Effects of methimepip and JNJ-5207852 in Wistar rats exposed to an open-field with and without object and in Balb/c mice exposed to a radial-arm maze. Front Syst Neurosci (2012) 0.81
H3 receptor blockade by thioperamide enhances cognition in rats without inducing locomotor sensitization. Psychopharmacology (Berl) (2003) 0.80
Approaches to measuring the effects of wake-promoting drugs: a focus on cognitive function. Hum Psychopharmacol (2009) 0.79
H3 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing retrieval. Psychopharmacology (Berl) (2008) 0.78
The effects of thioperamide on extracellular levels of glutamate and GABA in the rat prefrontal cortex. Psychopharmacology (Berl) (2009) 0.78
Interaction of nicotinic and histamine H(3) systems in the radial-arm maze repeated acquisition task. Eur J Pharmacol (2007) 0.77
Single dose of H3 receptor antagonist--ciproxifan--abolishes negative effects of chronic stress on cognitive processes in rats. Psychopharmacology (Berl) (2013) 0.77
Histaminergic modulation of nonspecific plasticity of the auditory system and differential gating. J Neurophysiol (2012) 0.76
The Synergistic Enhancing-Memory Effect of Donepezil and S 38093 (a Histamine H3 Antagonist) Is Mediated by Increased Neural Activity in the Septo-hippocampal Circuitry in Middle-Aged Mice. Front Pharmacol (2016) 0.76
Facilitation of short-term memory by histaminergic neurons in the nucleus accumbens is independent of cholinergic and glutamatergic transmission. Br J Pharmacol (2013) 0.76
On the Role of Histamine Receptors in the Regulation of Circadian Rhythms. PLoS One (2015) 0.76
Involvement of histaminergic inputs in the jaw-closing reflex arc. J Neurophysiol (2015) 0.76
Histaminergic modulation of cholinergic release from the nucleus basalis magnocellularis into insular cortex during taste aversive memory formation. PLoS One (2014) 0.75
Ligand autoradiographical quantification of histamine H3 receptor in human dementia with Lewy bodies. Pharmacol Res (2016) 0.75
Differential effects of the histamine H(3) receptor agonist methimepip on dentate granule cell excitability, paired-pulse plasticity and long-term potentiation in prenatal alcohol-exposed rats. Alcohol Clin Exp Res (2014) 0.75
S 38093, a histamine H3 antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice. Sci Rep (2017) 0.75
Definition and antagonism of histamine H 2 -receptors. Nature (1972) 18.58
Place navigation impaired in rats with hippocampal lesions. Nature (1982) 15.79
A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data. Behav Brain Res (1988) 7.29
Receptors mediating some actions of histamine. Br J Pharmacol Chemother (1966) 6.93
Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor. Nature (1983) 4.24
Dimaprit -(S-[3-(N,N-dimethylamino)prophyl]isothiourea) - a highly specific histamine H2 -receptor agonist. Part 1. Pharmacology. Agents Actions (1977) 3.33
Highly potent and selective ligands for histamine H3-receptors. Nature (1987) 2.90
Histaminergic transmission in the mammalian brain. Physiol Rev (1991) 2.28
Distribution of the histaminergic neuron system in the central nervous system of rats; a fluorescent immunohistochemical analysis with histidine decarboxylase as a marker. Brain Res (1984) 1.80
A behavioural analysis of spatial localization following electrolytic, kainate- or colchicine-induced damage to the hippocampal formation in the rat. Behav Brain Res (1983) 1.69
Histamine-immunoreactive nerve fibers in the rat brain. Neuroscience (1989) 1.52
The inhibitory effect of adenosine and related nucleotides on the release of acetylcholine. Neuroscience (1976) 1.42
Inhibition of noradrenaline release in the rat brain cortex via presynaptic H3 receptors. Naunyn Schmiedebergs Arch Pharmacol (1989) 1.37
Noradrenaline inhibition of acetylcholine release from guinea-pig brain. Eur J Pharmacol (1978) 1.30
Is the histaminergic neuron system a regulatory center for whole-brain activity? Trends Neurosci (1991) 1.30
Autoinhibition of histamine synthesis mediated by presynaptic H3-receptors. Neuroscience (1987) 1.30
Three histamine receptors (H1, H2 and H3) visualized in the brain of human and non-human primates. Brain Res (1990) 1.29
A detailed autoradiographic mapping of histamine H3 receptors in rat brain areas. Neuroscience (1993) 1.29
The role of interactions between the cholinergic system and other neuromodulatory systems in learning and memory. Synapse (1991) 1.23
Histamine H3 receptor-mediated inhibition of serotonin release in the rat brain cortex. Naunyn Schmiedebergs Arch Pharmacol (1988) 1.22
S-[2-(4-imidazolyl)ethyl]isothiourea, a highly specific and potent histamine H3 receptor agonist. J Pharmacol Exp Ther (1992) 1.22
Histamine H3 receptors modulate the release of [3H]-acetylcholine from slices of rat entorhinal cortex: evidence for the possible existence of H3 receptor subtypes. Br J Pharmacol (1992) 1.18
Histamine inhibits dopamine release in the mouse striatum via presynaptic H3 receptors. J Neural Transm Gen Sect (1993) 1.16
Cyanoguanidine-thiourea equivalence in the development of the histamine H2-receptor antagonist, cimetidine. J Med Chem (1977) 1.10
Frontal lobes and behaviour. Curr Opin Neurobiol (1994) 1.10
Facilitation of acetylcholine release and cognitive performance by an M(2)-muscarinic receptor antagonist in aged memory-impaired. J Neurosci (1995) 1.09
Scope and limitations of in vivo brain dialysis: a comparison of its application to various neurotransmitter systems. Life Sci (1987) 1.06
Thioperamide, the selective histamine H3 receptor antagonist, attenuates stimulant-induced locomotor activity in the mouse. Eur J Pharmacol (1994) 1.04
Histamine as a neuroregulator. Annu Rev Neurosci (1986) 1.00
Decreased brain choline uptake in older adults. An in vivo proton magnetic resonance spectroscopy study. JAMA (1995) 0.97
Effects of physostigmine and scopolamine on rats' performances in object-recognition and radial-maze tests. Psychopharmacology (Berl) (1992) 0.96
Cholinergic nucleus basalis neurons are excited by histamine in vitro. Neuroscience (1995) 0.93
High affinity histamine binding site is the H3 receptor: characterization and autoradiographic localization in rat brain. Synapse (1991) 0.93
HISTAMINE AND THE NERVOUS SYSTEM. Fed Proc (1965) 0.93
Stimulation of histamine H2 receptor in rat hypothalamus releases endogenous norepinephrine. J Pharmacol Exp Ther (1989) 0.91
Histamine potentiates N-methyl-D-aspartate responses in acutely isolated hippocampal neurons. Neuron (1993) 0.91
Nordimaprit, homodimaprit, clobenpropit and imetit: affinities for H3 binding sites and potencies in a functional H3 receptor model. Naunyn Schmiedebergs Arch Pharmacol (1993) 0.90
Characterization of histamine H3 receptors regulating acetylcholine release in rat entorhinal cortex. Br J Pharmacol (1995) 0.89
Cellular localization and possible functions for brain histamine: recent progress. Prog Neurobiol (1988) 0.89
A new potent and selective histamine H3 receptor agonist, 4-(1H-imidazol-4-ylmethyl)piperidine. J Med Chem (1994) 0.88
NMDA receptor antagonists decrease GABA outflow from the septum and increase acetylcholine outflow from the hippocampus: a microdialysis study. J Neurosci (1994) 0.86
Histaminergic modulation of hippocampal acetylcholine release in vivo. J Neurochem (1994) 0.85
Effects of thioperamide, a histamine H3 antagonist, on the step-through passive avoidance response and histidine decarboxylase activity in senescence-accelerated mice. Pharmacol Biochem Behav (1995) 0.85
Interactions between oxiracetam, aniracetam and scopolamine on behavior and brain acetylcholine. Pharmacol Biochem Behav (1987) 0.83
Effects of (R)-alpha-methylhistamine and scopolamine on spatial learning in the rat assessed using a water maze. Psychopharmacology (Berl) (1994) 0.82
Influence of histamine depletion on learning and memory recollection in rats. Psychopharmacology (Berl) (1993) 0.82
Cholinergic modulation of memory in rats. Psychopharmacology (Berl) (1985) 0.81
Influence of age and gender on the levels of histamine metabolites and pros-methylimidazoleacetic acid in human cerebrospinal fluid. Arch Gerontol Geriatr (2004) 0.81
Elevated levels of histamine metabolites in cerebrospinal fluid of aging, healthy humans. Compr Gerontol A (1988) 0.81
Histamine H3 receptor inhibition of K(+)-evoked release of acetylcholine from rat cortex in vivo. Inflamm Res (1996) 0.79
Dopamine inhibition of the release of endogenous acetylcholine from corpus striatum and cerebral cortex in tissue slices and synaptosomes: a presynaptic response? J Neurochem (1982) 0.79
Histidine decarboxylase inhibition induced by alpha-fluoromethylhistidine provokes learning-related hypokinetic activity. Agents Actions (1991) 0.79
Participation of histamine in the step-through active avoidance response and its inhibition by H1-blockers. Jpn J Pharmacol (1991) 0.78
Intracerebroventricular histamine, but not 48/80, causes posttraining memory facilitation in the rat. Arch Int Pharmacodyn Ther (1988) 0.78
Strain differences in regional brain histamine levels between genetically epilepsy-prone and resistant rats. Methods Find Exp Clin Pharmacol (1992) 0.77
Is monoamine turnover in the brain regulated by histamine H3 receptors? Eur J Pharmacol (1990) 0.77
Effects of thioperamide on the cholinergic system and the step-through passive avoidance test in mice. Methods Find Exp Clin Pharmacol (1995) 0.77
Effects of (S)-alpha-fluoromethylhistidine and (R)-alpha-methylhistamine on locomotion of W/Wv mice. Pharmacol Biochem Behav (1993) 0.76
Facilitation of learning in adult and aged rats following bilateral lesions of the tuberomammillary nucleus region. Behav Brain Res (1994) 0.76
Structural influences upon antihistamine activity; 3-amino-1-aryl-1-(2-pyridyl)propenes and related compounds. J Pharm Pharmacol (1971) 0.76
International Union of Pharmacology. XIII. Classification of histamine receptors. Pharmacol Rev (1997) 2.71
Performance assessment of new multiplex probe assay for identification of mycobacteria. J Clin Microbiol (2001) 2.68
The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol (2013) 2.48
Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation. Proc Natl Acad Sci U S A (1993) 1.98
Comparison of Mycobacterium tuberculosis susceptibility testing performed with BACTEC 460TB (Becton Dickinson) and MB/BacT (Organon Teknika) systems. Diagn Microbiol Infect Dis (2000) 1.65
Constitutive signaling of the human cytomegalovirus-encoded chemokine receptor US28. J Biol Chem (2001) 1.62
Alterations in behaviour and glutamate transmission following presentation of stimuli previously associated with cocaine exposure. Eur J Neurosci (2001) 1.57
Effects of novelty and habituation on acetylcholine, GABA, and glutamate release from the frontal cortex and hippocampus of freely moving rats. Neuroscience (2001) 1.50
Is histamine the final neurotransmitter in the entrainment of circadian rhythms in mammals? Trends Pharmacol Sci (2000) 1.47
Molecular pharmacological aspects of histamine receptors. Pharmacol Ther (1995) 1.47
Effects of chronic antidepressant treatments on serotonin transporter function, density, and mRNA level. J Neurosci (1999) 1.42
The effect of mutations in the DRY motif on the constitutive activity and structural instability of the histamine H(2) receptor. Mol Pharmacol (2000) 1.41
[Improper equalization of sumatriptan with ergotamine and dihydroergotamine in the Drug Equivalency System]. Ned Tijdschr Geneeskd (1993) 1.40
Biosynthesis and degradation of peptides derived from Xenopus laevis prohormones. Biochem J (1987) 1.38
Use of an internal standard to measure pyridinoline and deoxypyridinoline in urine. Clin Chem (1994) 1.38
Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3). J Invest Dermatol (1999) 1.37
The effects of selected probiotic strains on the development of eczema (the PandA study). Allergy (2009) 1.34
Identification of rat H3 receptor isoforms with different brain expression and signaling properties. Mol Pharmacol (2001) 1.29
A novel rat serotonin (5-HT6) receptor: molecular cloning, localization and stimulation of cAMP accumulation. Biochem Biophys Res Commun (1993) 1.27
Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors. Proc Natl Acad Sci U S A (1996) 1.25
The histamine H4 receptor is functionally expressed on neurons in the mammalian CNS. Br J Pharmacol (2009) 1.22
Thiazole and thiadiazole analogues as a novel class of adenosine receptor antagonists. J Med Chem (2001) 1.21
Histamine inhibits the production of interleukin-12 through interaction with H2 receptors. J Clin Invest (1998) 1.20
Adenosine decreases aspartate and glutamate release from rat hippocampal slices. Eur J Pharmacol (1984) 1.19
A home-based exercise program for nondisabled older adults. J Am Geriatr Soc (1996) 1.19
Constitutive activity of the histamine H(1) receptor reveals inverse agonism of histamine H(1) receptor antagonists. Eur J Pharmacol (2000) 1.17
Improgan, a cimetidine analog, induces morphine-like antinociception in opioid receptor-knockout mice. Brain Res (2000) 1.16
Investigations into the acetylcholine output from the cerebral cortex of the cat in the presence of hyoscine. Br J Pharmacol Chemother (1967) 1.15
Effect of psychoactive drugs on the output of acetylcholine from the cerebral cortex of the cat. Eur J Pharmacol (1968) 1.15
Short-term desensitization of the histamine H1 receptor in human HeLa cells: involvement of protein kinase C dependent and independent pathways. Br J Pharmacol (1992) 1.14
Proteomic identification of proteins specifically oxidized by intracerebral injection of amyloid beta-peptide (1-42) into rat brain: implications for Alzheimer's disease. Neuroscience (2005) 1.14
Histamine H(1)-receptor activation of nuclear factor-kappa B: roles for G beta gamma- and G alpha(q/11)-subunits in constitutive and agonist-mediated signaling. Mol Pharmacol (2001) 1.13
Aniracetam restores object recognition impaired by age, scopolamine, and nucleus basalis lesions. Pharmacol Biochem Behav (1996) 1.11
Calcium antagonism and structure-affinity relationships of terfenadine, a histamine H1 antagonist, and some related compounds. J Pharm Pharmacol (1993) 1.09
Quantitative expression profiling of G-protein-coupled receptors (GPCRs) in metastatic melanoma: the constitutively active orphan GPCR GPR18 as novel drug target. Pigment Cell Melanoma Res (2010) 1.08
Therapeutic potential of histamine H3 receptor agonists and antagonists. Trends Pharmacol Sci (1998) 1.07
Estrogen receptor beta in the paraventricular nucleus of hypothalamus regulates the neuroendocrine response to stress and is regulated by corticosterone. Neuroscience (2003) 1.07
Agonist-independent regulation of constitutively active G-protein-coupled receptors. Trends Biochem Sci (1998) 1.05
The origin, effects and control of air pollution in laboratories used for human embryo culture. Hum Reprod (1998) 1.05
Investigation on acetylcholine, aspartate, glutamate and GABA extracellular levels from ventral hippocampus during repeated exploratory activity in the rat. Neurochem Res (2003) 1.03
Effects of morphine on brain and spinal acetylcholine levels and nociceptive threshold in the frog. Brain Res (1974) 1.02
Synthesis of benzylideneacetophenones and their inhibition of lipid peroxidation. Eur J Med Chem (2000) 1.02
HA autoreceptor assay with superfused slices of rat brain cortex and electrical stimulation. Eur J Pharmacol (1987) 1.01
Inter-individual differences in novelty-seeking behavior in rats predict differential responses to desipramine in the forced swim test. Psychopharmacology (Berl) (2008) 1.01
Interleukin-1beta activates forebrain glial cells and increases nitric oxide production and cortical glutamate and GABA release in vivo: implications for Alzheimer's disease. Neuroscience (1999) 1.01
Novel selective PDE4 inhibitors. 2. Synthesis and structure-activity relationships of 4-aryl-substituted cis-tetra- and cis-hexahydrophthalazinones. J Med Chem (2001) 1.01
Cloning and tissue expression of a rat histamine H2-receptor gene. Biochem Biophys Res Commun (1991) 1.01
Pulmonary function in non-insulin-dependent diabetes mellitus. Respiration (2001) 1.01
Taurine distribution in cat brain. J Neurochem (1972) 1.00
Investigations into the adenosine outflow from hippocampal slices evoked by ischemia-like conditions. J Neurochem (1993) 0.99
Enhanced acetylcholine release in the hippocampus and cortex during acquisition of an operant behavior. Brain Res (1996) 0.99
Experimental brain inflammation and neurodegeneration as model of Alzheimer's disease: protective effects of selective COX-2 inhibitors. Int J Immunopathol Pharmacol (2003) 0.99
Modulation of forskolin-mediated adenylyl cyclase activation by constitutively active G(S)-coupled receptors. FEBS Lett (1997) 0.98
Expression of a cloned rat histamine H2 receptor mediating inhibition of arachidonate release and activation of cAMP accumulation. Proc Natl Acad Sci U S A (1992) 0.98
Homologous histamine H1 receptor desensitization results in reduction of H1 receptor agonist efficacy. Eur J Pharmacol (1991) 0.98
The selective cyclooxygenase-2 inhibitor rofecoxib suppresses brain inflammation and protects cholinergic neurons from excitotoxic degeneration in vivo. Neuroscience (2003) 0.98
Effects of histamine H1-, H2- and H3-receptor selective drugs on the mechanical activity of guinea-pig small and large intestine. Br J Pharmacol (1991) 0.97
A novel class of adenosine A3 receptor ligands. 2. Structure affinity profile of a series of isoquinoline and quinazoline compounds. J Med Chem (1998) 0.97
Isoquinoline and quinazoline urea analogues as antagonists for the human adenosine A(3) receptor. J Med Chem (2000) 0.97
Activation of brain stem nuclei by improgan, a non-opioid analgesic. Brain Res (2004) 0.97
Differential effects of social defeat in rats with high and low locomotor response to novelty. Neuroscience (2011) 0.96
Characterization of the binding of the first selective radiolabelled histamine H3-receptor antagonist, [125I]-iodophenpropit, to rat brain. Br J Pharmacol (1994) 0.96
Mutational analysis of the antagonist-binding site of the histamine H(1) receptor. J Biol Chem (1999) 0.95
Selective muscarinic antagonists differentially affect in vivo acetylcholine release and memory performances of young and aged rats. Neuroscience (1997) 0.95
A disbalance between beta-adrenergic and muscarinic responses caused by hydrogen peroxide in rat airways in vitro. Biochem Biophys Res Commun (1987) 0.95
A2 adenosine receptors: their presence and neuromodulatory role in the central nervous system. Gen Pharmacol (1996) 0.94
Consensus Group on New-Generation Antihistamines (CONGA): present status and recommendations. Clin Exp Allergy (2003) 0.94
Oxiracetam prevents electroshock-induced decrease in brain acetylcholine and amnesia. Eur J Pharmacol (1986) 0.94
Changes in cortical acetylcholine output induced by modulation of the nucleus basalis. Brain Res Bull (1986) 0.93
Effect of adenosine, adenosine triphosphate, adenosine deaminase, dipyridamole and aminophylline on acetylcholine release from electrically-stimulated brain slices. Neuropharmacology (1983) 0.93
The cDNA sequence coding for prepro-PGS (prepro-magainins) and aspects of the processing of this prepro-polypeptide. J Biol Chem (1988) 0.93
Pivotal role for the cytoplasmic carboxyl-terminal tail of a nonmammalian gonadotropin-releasing hormone receptor in cell surface expression, ligand binding, and receptor phosphorylation and internalization. Mol Pharmacol (1999) 0.93
A1 and A2 adenosine receptors modulate acetylcholine release from brain slices. Eur J Pharmacol (1984) 0.92
Electrical stimulation of the stratum radiatum increases the release and neosynthesis of aspartate, glutamate, and gamma-aminobutyric acid in rat hippocampal slices. J Neurochem (1983) 0.92
Regional differences in the electrically stimulated release of endogenous and radioactive adenosine and purine derivatives from rat brain slices. Naunyn Schmiedebergs Arch Pharmacol (1990) 0.92
Temporal correlation between adenosine outflow and synaptic potential inhibition in rat hippocampal slices during ischemia-like conditions. Brain Res (1998) 0.92
Inhibition of improgan antinociception by the cannabinoid (CB)(1) antagonist N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A): lack of obligatory role for endocannabinoids acting at CB(1) receptors. J Pharmacol Exp Ther (2002) 0.92
Effect of bicuculline and strychnine on the acetylcholine content of the amphibian spinal cord. Br J Pharmacol (1972) 0.92
A simple and rapid in vitro test system for the screening of histamine H3 ligands. Methods Find Exp Clin Pharmacol (1992) 0.91
Differential effects of amyloid peptides beta-(1-40) and beta-(25-35) injections into the rat nucleus basalis. Neuroscience (1995) 0.91
New insights into the second generation antihistamines. Drugs (2001) 0.91
A third life for burimamide. Discovery and characterization of a novel class of non-opioid analgesics derived from histamine antagonists. Ann N Y Acad Sci (2000) 0.91
NO synthesis inhibition decreases cortical ACh release and impairs retention of a conditioned response. Brain Res (2001) 0.91