Autophagy.

Autophagy as a regulated pathway of cellular degradation. Science (2000) 17.27

Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole. EMBO J (1998) 4.38

Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways. J Cell Biol (2000) 4.30

Cvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuole. J Cell Biol (2001) 4.25

Brucella abortus transits through the autophagic pathway and replicates in the endoplasmic reticulum of nonprofessional phagocytes. Infect Immun (1998) 3.92

Autophagy in the eukaryotic cell. Eukaryot Cell (2002) 3.61

Changes in the proteolytic activities of proteasomes and lysosomes in human fibroblasts produced by serum withdrawal, amino-acid deprivation and confluent conditions. Biochem J (2003) 1.89

Recent progress in understanding protein and lipid factors affecting hepatic VLDL assembly and secretion. Nutr Metab (Lond) (2010) 1.43

Sepsis induces extensive autophagic vacuolization in hepatocytes: a clinical and laboratory-based study. Lab Invest (2009) 1.41

Autophagy and the cvt pathway both depend on AUT9. J Bacteriol (2000) 1.19

Lewy body-like α-synuclein aggregates resist degradation and impair macroautophagy. J Biol Chem (2013) 1.18

A new molecular link between the fibrillar and granulovacuolar lesions of Alzheimer's disease. Am J Pathol (1999) 1.02

Mitochondrial Dysfunction: The Road to Alpha-Synuclein Oligomerization in PD. Parkinsons Dis (2011) 0.99

Autophagy: mechanism and physiological relevance 'brewed' from yeast studies. Front Biosci (Schol Ed) (2012) 0.85

Mitochondrial imaging in dorsal root ganglion neurons following the application of inducible adenoviral vector expressing two fluorescent proteins. J Neurosci Methods (2008) 0.81

Lipofuscin accumulation and autophagy in glaucomatous human lamina cribrosa cells. BMC Ophthalmol (2014) 0.79

Recruitment of the oncoprotein v-ErbA to aggresomes. Mol Cell Endocrinol (2010) 0.78

Neuroprotective effect of cellular prion protein (PrPC) is related with activation of alpha7 nicotinic acetylcholine receptor (α7nAchR)-mediated autophagy flux. Oncotarget (2015) 0.76

Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence. Biophys J (1999) 2.96

Autolysosomal membrane-associated betaine homocysteine methyltransferase. Limited degradation fragment of a sequestered cytosolic enzyme monitoring autophagy. J Biol Chem (1999) 2.23

Photosensitization with zinc (II) phthalocyanine as a switch in the decision between apoptosis and necrosis. Cancer Res (2001) 1.15

Quantitation and facilitated de novo sequencing of proteins by isotopic N-terminal labeling of peptides with a fragmentation-directing moiety. Anal Chem (2000) 1.13

Imaging the mitochondrial permeability transition pore in intact cells. Biofactors (1998) 1.10

Effect of bile duct ligation on bile acid metabolism in rats. J Lipid Res (1981) 1.03

Multiphasic control of hepatic protein degradation by regulatory amino acids. General features and hormonal modulation. J Biol Chem (1987) 0.98

Factor analysis of the EMBU scale in a large sample of Japanese volunteers. Acta Psychiatr Scand (1999) 0.97

Leucine-specific binding of photoreactive Leu7-MAP to a high molecular weight protein on the plasma membrane of the isolated rat hepatocyte. Biochem Biophys Res Commun (1994) 0.95

Multiphasic control of proteolysis by leucine and alanine in the isolated rat hepatocyte. Am J Physiol (1994) 0.95

Characteristics of perceived parenting styles in Japan using the EMBU scale. Acta Psychiatr Scand (1999) 0.94

Helodermin has a VIP-like effect upon canine blood flow. Peptides (1986) 0.93

Postoperative adhesion prevention with an oxidized regenerated cellulose adhesion barrier in infertile women. J Reprod Med (2000) 0.92

Ovarian secretion of progesterone and 20alpha-hydroxypregn-4-en-3-one during rat estrous cycle in chronological relation to pituitary release of luteinizing hormone. Endocrinol Jpn (1969) 0.91

Mechanism of autophagy in permeabilized hepatocytes: evidence for regulation by GTP binding proteins. Adv Exp Med Biol (1996) 0.90

Leupeptin-induced appearance of partial fragment of betaine homocysteine methyltransferase during autophagic maturation in rat hepatocytes. J Biochem (2001) 0.90

Combined blockade of 5-HT3- and 5-HT4-serotonin receptors inhibits colonic functions in conscious rats and mice. J Pharmacol Exp Ther (1997) 0.89

Determination of L-carnitine, acetyl-L-carnitine and propionyl-L-carnitine in human plasma by high-performance liquid chromatography after pre-column derivatization with 1-aminoanthracene. J Chromatogr B Biomed Appl (1996) 0.89

Natto mucilage containing poly-gamma-glutamic acid increases soluble calcium in the rat small intestine. Biosci Biotechnol Biochem (2001) 0.89

Relationship between ovarian progestin secretion and corpora lutea function in pregnant rats. Endocrinol Jpn (1970) 0.88

Altered bile acid metabolism in alloxan diabetic rats. Jpn J Pharmacol (1979) 0.88

On the mechanism of spermine transport in liver mitochondria. J Biol Chem (1988) 0.88

Enhanced colonic peristalsis by impairment of nitrergic enteric neurons in spontaneously diabetic rats. Auton Neurosci (2001) 0.88

Identification of autolysosomes directly associated with proteolysis on the density gradients in isolated rat hepatocytes. J Biochem (1998) 0.87

The effect of microbial contamination on musculocutaneous and random flaps. J Surg Res (1986) 0.87

Amino acid control of proteolysis in perfused livers of synchronously fed rats. Mechanism and specificity of alanine co-regulation. J Biol Chem (1991) 0.86

Effects of gender difference and birth order on perceived parenting styles, measured by the EMBU scale, in Japanese two-sibling subjects. Psychiatry Clin Neurosci (2000) 0.86

A novel boronated-porphyrin as a radio-sensitizing agent for boron neutron capture therapy of tumours: in vitro and in vivo studies. Appl Radiat Isot (2009) 0.85

Age-related changes in cholesterol and bile acid metabolism in rats. J Lipid Res (1978) 0.84

Inhibition of macroautophagy and proteolysis in the isolated rat hepatocyte by a nontransportable derivative of the multiple antigen peptide Leu8-Lys4-Lys2-Lys-beta Ala. J Biol Chem (1994) 0.83

5-HT activates nitric oxide-generating neurons to stimulate chloride secretion in guinea pig distal colon. Am J Physiol (1998) 0.83

Ganglioside GM1 protection from apoptosis of rat heart fibroblasts. Arch Biochem Biophys (1999) 0.82

Control of hepatic proteolysis by leucine and isovaleryl-L-carnitine through a common locus. Evidence for a possible mechanism of recognition at the plasma membrane. J Biol Chem (1992) 0.82

Effect of dietary cholesterol on cholesterol and bile acid metabolism in rats. Jpn J Pharmacol (1977) 0.82

In situ identification of messenger RNA of endothelial type nitric oxide synthase in rat cardiac myocytes. Biochem Biophys Res Commun (1996) 0.82

De novo autophagic vacuole formation in hepatocytes permeabilized by Staphylococcus aureus alpha-toxin. Inhibition by nonhydrolyzable GTP analogs. J Biol Chem (1994) 0.80

Gene expression of myostatin during development and regeneration of skeletal muscle in Japanese Black Cattle. J Anim Sci (2006) 0.79

Involvement of 5-HT3 and 5-HT4 receptors in the motor activity of isolated vascularly perfused rat duodenum. Neurogastroenterol Motil (1999) 0.79

Transport and function of L-carnitine and L-propionylcarnitine: relevance to some cardiomyopathies and cardiac ischemia. Z Kardiol (1987) 0.78

Disturbance of cholesterol and bile acid metabolism in spontaneously hypertensive rats (SHR). J Biochem (1978) 0.78

Dextran derivatives in single and combination chemotherapy against transplantable mouse ascites and solid tumors. Cancer Res (1977) 0.78

Mitochondrial alterations induced by aspirin in rat hepatocytes expressing mitochondrially targeted green fluorescent protein (mtGFP). FEBS Lett (1996) 0.77

Rat pancreas contains the proglucagon(64-69) fragment and arginine stimulates its release. FEBS Lett (1985) 0.77

Further studies on the luteotropic action of estrogen in rats. Endocrinol Jpn (1973) 0.77

Pharmacological profile of FK480, a novel cholecystokinin type-A receptor antagonist: comparison to loxiglumide. J Pharmacol Exp Ther (1994) 0.77

Ca2+-mediated action of long-chain acyl-CoA on liver mitochondria energy-linked processes. Biochim Biophys Acta (1989) 0.76

Rhythmic spontaneous contractions in the rat proximal colon. Jpn J Physiol (2001) 0.76

Morphological demonstration of a vagal inhibitory pathway to the lower esophageal sphincter via nitrergic neurons in the rat esophagus. Neurogastroenterol Motil (2013) 0.76

A remnant tubal pregnancy after cloacal malformation repair. Fertil Steril (2001) 0.76

Effects of insulin, amino acids and fasting on myofibrillar protein degradation in perfused hindquarters of rats. J Nutr Sci Vitaminol (Tokyo) (1985) 0.76

Choleretic effect of Artemisia capillaris extract in rats. Jpn J Pharmacol (1981) 0.76

Pharmacological characterization of FK1052, a dihydropyridoindole derivative, as a new serotonin 3 and 4 dual receptor antagonist. J Pharmacol Exp Ther (1993) 0.75

[Useful hints for practical nursing students preparing for the Board Examination]. Kango Kyoshitsu (1968) 0.75

[Iatrogenic incidents and compensation]. Kango Gijutsu (1981) 0.75

Effects of exogenous progesterone on the ovarian progestin secretion and plasma LH and prolactin levels in cyclic rats. Endocrinol Jpn (1972) 0.75

[Hypocholesterolemic action of 17-dimethylaminoethoxyiminosteroids in rats]. Nihon Naibunpi Gakkai Zasshi (1966) 0.75

Regulation of taste-active components of meat by dietary branched-chain amino acids; effects of branched-chain amino acid antagonism. Br Poult Sci (2008) 0.75

Effect of exogenous progesterone on the preovulatory progesterone secretion in the rat. Endocrinol Jpn (1969) 0.75

[Legal relationship between dentists and patients--problems in clinical dentistry]. Shikai Tenbo (1978) 0.75

Proceedings: 2 alpha, 3 alpha-epithio-5alpha-androstan-17beta-YL 1-methoxy-cyclophenyl ether (10364-S), a new orally active anabolic-androgenic steroid. Jpn J Pharmacol (1974) 0.75

[Ownership of dentures--in relation to the billing of dental fees]. Shikai Tenbo (1978) 0.75

[Biphasic effects of estrogens on the plasma cholesterol level in rats]. Nihon Naibunpi Gakkai Zasshi (1967) 0.75

2alpha, 3alpha-epithio-5alpha-androstan-17beta-yl 1-methoxycyclopentyl ether (10361-S), a new orally active anabolic-androgenic steroid. Jpn J Pharmacol (1974) 0.75

Distribution of bile acids in rats. Lipids (1978) 0.75

[Effect of clothing on physiological responses when female subjects enter a cooling room]. Nihon Eiseigaku Zasshi (1971) 0.75

Effects of synthetic progestational steroids on liver and serum lipids in rats. Endocrinol Jpn (1976) 0.75

L-carnitine decreases the recovery time following halothane anesthesia in rats. Agressologie (1987) 0.75

The "carnitine system": recent aspects. Adv Exp Med Biol (1994) 0.75

Nociceptin inhibits capsaicin-sensitive contraction to mesenteric nerve stimulation in the guinea-pig isolated ileum. Auton Neurosci (2000) 0.75

Inhibitory action of isovaleryl-L-carnitine on proteolysis in perfused rat liver. Biochem Biophys Res Commun (1989) 0.75

A pulsatile pump for cardiopulmonary bypass and its clinical use. Jpn J Surg (1988) 0.75

[Phototherapy of infants with hyperbilirubinemia associated with low birth weight]. Josanpu Zasshi (1978) 0.75

Biphasic effect of estrogen on rat plasma cholesterol level and its interaction by androgen. Endocrinol Jpn (1969) 0.75

[Nursing questions and answers. Clinical tests and nursing, a diagnostic process]. Kango Kyoshitsu (1973) 0.75

Effects of estradiol, dietary cholesterl and 1-thyroxine on biliary bile acid composition and secretory rate, and on plasma, liver and bile cholesterol levels in rats. Endocrinol Jpn (1970) 0.75

[On the degree-awarding nursing course for practical nurses. Advice for candidates for evening courses]. Kango Kyoshitsu (1975) 0.75

[Method for serial determination of skin temperature during cold exposure]. Igaku To Seibutsugaku (1970) 0.75

Further studies on the effect of exogenous progesterone and related compounds on the preovulatory progesterone secretion in the rat. Endocrinol Jpn (1970) 0.75

Stimulative and inhibitive effects of estrogen on cholesterol synthesis in rats. Endocrinol Jpn (1973) 0.75

[Late occlusion at the anastomosis site of an extended polytetrafluoroethylene (E-PTFE) graft with small caliber]. Nihon Geka Gakkai Zasshi (1988) 0.75

[Effects of phototherapy on low birth weight infants with hyperbilirubinemia, with special reference to frequency of defecation and condition of the feces]. Josanpu Zasshi (1979) 0.75

[Dentist and death of a patient due to shock--legal questions concerning medical history taking]. Shikai Tenbo (1978) 0.75

Luteotrophic action of estrogen and prolactin in rats. Endocrinol Jpn (1970) 0.75

[A study on adhesives for polyaddition-type silicone impression materials. Part 1]. Nihon Hotetsu Shika Gakkai Zasshi (1988) 0.75

[Method of comparison of chronological changes of skin temperature under various conditions]. Igaku To Seibutsugaku (1970) 0.75

Acute effects of various gonadotropins and other pituitary hormones on preovulatory ovarian progestin secretion in hypophysectomized rats. Endocrinol Jpn (1969) 0.75

A decreased number of primordial germ cells and the small numbers and reduced sizes of germinal granules in the periodic albino mutant of Xenopus laevis. Dev Biol (1993) 0.75

[Purposeful evasion of payment by patients--dental contracts and the dentist's rights]. Shikai Tenbo (1978) 0.75

New method for evaluating intestinal contractions in guinea pig by curve fitting. Dig Dis Sci (2000) 0.75

4-Amino-6-methylhept-2-enoic acid: a leucine analogue and potential probe for localizing sites of proteolytic control in the hepatocyte. Biochem Biophys Res Commun (1992) 0.75

[Review for the 2d year student. Nursing of urological patients]. Kango Kyoshitsu (1968) 0.75

Regulation of taste-active components of meat by dietary leucine. Br Poult Sci (2007) 0.75

Effect of chondroitin sulfate A in combination therapy with mitomycin C on sarcoma 180 ascites tumor. Chem Pharm Bull (Tokyo) (1980) 0.75