Published in J Biol Chem on January 31, 1997
ADP-ribosylation factor 6 regulates a novel plasma membrane recycling pathway. J Cell Biol (1997) 4.76
Phosphatidylinositol 4,5-bisphosphate and Arf6-regulated membrane traffic. J Cell Biol (2001) 3.70
EFA6, a sec7 domain-containing exchange factor for ARF6, coordinates membrane recycling and actin cytoskeleton organization. EMBO J (1999) 2.63
Sorting and storage during secretory granule biogenesis: looking backward and looking forward. Biochem J (1998) 2.61
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ADP-ribosylation factor 6 regulates actin cytoskeleton remodeling in coordination with Rac1 and RhoA. Mol Cell Biol (2000) 1.91
ARF6 regulates a plasma membrane pool of phosphatidylinositol(4,5)bisphosphate required for regulated exocytosis. J Cell Biol (2003) 1.82
Phospholipase D1: a key factor for the exocytotic machinery in neuroendocrine cells. EMBO J (2001) 1.67
Remodeling of the actin cytoskeleton is coordinately regulated by protein kinase C and the ADP-ribosylation factor nucleotide exchange factor ARNO. Mol Biol Cell (1998) 1.56
Peroxisome biogenesis: involvement of ARF and coatomer. J Cell Biol (1998) 1.51
Calcium-regulated exocytosis of dense-core vesicles requires the activation of ADP-ribosylation factor (ARF)6 by ARF nucleotide binding site opener at the plasma membrane. J Cell Biol (2002) 1.33
Separation of membrane trafficking and actin remodeling functions of ARF6 with an effector domain mutant. Mol Cell Biol (2000) 1.33
ADP-ribosylation factor 6 regulates insulin secretion through plasma membrane phosphatidylinositol 4,5-bisphosphate. Proc Natl Acad Sci U S A (2003) 1.31
ADP-ribosylation factor 1 controls the activation of the phosphatidylinositol 3-kinase pathway to regulate epidermal growth factor-dependent growth and migration of breast cancer cells. J Biol Chem (2008) 1.27
GEP100/BRAG2: activator of ADP-ribosylation factor 6 for regulation of cell adhesion and actin cytoskeleton via E-cadherin and alpha-catenin. Proc Natl Acad Sci U S A (2006) 1.20
Arf6 plays an early role in platelet activation by collagen and convulxin. Blood (2005) 1.12
Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 β-cells and rat islets. Biochem Pharmacol (2011) 1.03
The ADP ribosylation factor nucleotide exchange factor ARNO promotes beta-arrestin release necessary for luteinizing hormone/choriogonadotropin receptor desensitization. Proc Natl Acad Sci U S A (2000) 1.00
ADP-ribosylation factor 6 delineates separate pathways used by endothelin 1 and insulin for stimulating glucose uptake in 3T3-L1 adipocytes. Mol Cell Biol (2001) 0.97
ARF6 activated by the LHCG receptor through the cytohesin family of guanine nucleotide exchange factors mediates the receptor internalization and signaling. J Biol Chem (2012) 0.95
The hop cassette of the PAC1 receptor confers coupling to Ca2+ elevation required for pituitary adenylate cyclase-activating polypeptide-evoked neurosecretion. J Biol Chem (2007) 0.95
ARF6-dependent regulation of P2Y receptor traffic and function in human platelets. PLoS One (2012) 0.92
A presynaptic role for the ADP ribosylation factor (ARF)-specific GDP/GTP exchange factor msec7-1. Proc Natl Acad Sci U S A (1999) 0.92
The cortical acto-Myosin network: from diffusion barrier to functional gateway in the transport of neurosecretory vesicles to the plasma membrane. Front Endocrinol (Lausanne) (2013) 0.90
Localization of ADP-ribosylation factor domain protein 1 (ARD1) in lysosomes and Golgi apparatus. Proc Natl Acad Sci U S A (1998) 0.85
Phospholipase D in rat myometrium: occurrence of a membrane-bound ARF6 (ADP-ribosylation factor 6)-regulated activity controlled by betagamma subunits of heterotrimeric G-proteins. Biochem J (2000) 0.85
ADP-ribosylation factor 1 expression regulates epithelial-mesenchymal transition and predicts poor clinical outcome in triple-negative breast cancer. Oncotarget (2016) 0.82
Identification of lysosomal and Golgi localization signals in GAP and ARF domains of ARF domain protein 1. Mol Cell Biol (2000) 0.81
The small GTPase Arf6 is essential for the Tram/Trif pathway in TLR4 signaling. J Biol Chem (2013) 0.80
Cytohesin-2 phosphorylation by protein kinase C relieves the constitutive suppression of platelet dense granule secretion by ADP-ribosylation factor 6. J Thromb Haemost (2014) 0.79
Exchange factor EFA6R requires C-terminal targeting to the plasma membrane to promote cytoskeletal rearrangement through the activation of ADP-ribosylation factor 6 (ARF6). J Biol Chem (2014) 0.79
Elucidation of the CHO Super-Ome (CHO-SO) by Proteoinformatics. J Proteome Res (2015) 0.78
ADP ribosylation factor 6 (ARF6) promotes acrosomal exocytosis by modulating lipid turnover and Rab3A activation. J Biol Chem (2015) 0.78
Prenatal stress-induced programming of genome-wide promoter DNA methylation in 5-HTT-deficient mice. Transl Psychiatry (2014) 0.77
Binding of coatomer to Golgi membranes requires ADP-ribosylation factor. J Biol Chem (1993) 3.01
Valve repair in rheumatic mitral valve disease: is it always worth trying? J Heart Valve Dis (1997) 2.69
Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi-derived COP-coated vesicles. J Cell Biol (1993) 2.51
A major transmembrane protein of Golgi-derived COPI-coated vesicles involved in coatomer binding. J Cell Biol (1996) 2.20
Evidence for segregation of sphingomyelin and cholesterol during formation of COPI-coated vesicles. J Cell Biol (2000) 2.13
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beta-Arrestin-mediated ADP-ribosylation factor 6 activation and beta 2-adrenergic receptor endocytosis. J Biol Chem (2001) 1.63
Mid-term follow-up after heart valve replacement with CarboMedics bileaflet prostheses. J Thorac Cardiovasc Surg (1993) 1.62
Sphingomyelin-enriched microdomains at the Golgi complex. Mol Biol Cell (2001) 1.55
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Time-course of impairment of respiratory mechanics after cardiac surgery and cardiopulmonary bypass. Crit Care Med (1999) 1.46
The GIT family of ADP-ribosylation factor GTPase-activating proteins. Functional diversity of GIT2 through alternative splicing. J Biol Chem (2000) 1.44
Regulated exocytosis in chromaffin cells. Translocation of ARF6 stimulates a plasma membrane-associated phospholipase D. J Biol Chem (1998) 1.41
Direct and GTP-dependent interaction of ADP ribosylation factor 1 with coatomer subunit beta. Proc Natl Acad Sci U S A (1997) 1.41
Effect of low molecular weight heparin (fragmin) on bleeding after cardiac surgery. Ann Thorac Surg (2000) 1.40
Characterization of hormone and protein release from alpha-toxin-permeabilized chromaffin cells in primary culture. J Biol Chem (1986) 1.38
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Chromaffin cell calcium channel kinetics measured isotopically through fast calcium, strontium, and barium fluxes. J Biol Chem (1987) 1.27
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Recruitment to Golgi membranes of ADP-ribosylation factor 1 is mediated by the cytoplasmic domain of p23. EMBO J (2001) 1.25
Presence of three pertussis toxin substrates and Go alpha immunoreactivity in both plasma and granule membranes of chromaffin cells. FEBS Lett (1987) 1.24
Loss of proteins from digitonin-permeabilized adrenal chromaffin cells essential for exocytosis. J Biol Chem (1987) 1.23
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p24 and p23, the major transmembrane proteins of COPI-coated transport vesicles, form hetero-oligomeric complexes and cycle between the organelles of the early secretory pathway. FEBS Lett (1999) 1.18
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COUP-TF and Sp1 interact and cooperate in the transcriptional activation of the human immunodeficiency virus type 1 long terminal repeat in human microglial cells. J Biol Chem (1997) 1.18
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A reassessment of guanine nucleotide effects on catecholamine secretion from permeabilized adrenal chromaffin cells. J Biol Chem (1989) 1.13
Impairment of lung and chest wall mechanics in patients with acute respiratory distress syndrome: role of abdominal distension. Am J Respir Crit Care Med (1997) 1.12
Receptor-induced polymerization of coatomer. Proc Natl Acad Sci U S A (1999) 1.12
Immunocytochemical study of microtubules in chromaffin cells in culture and evidence that tubulin is not an integral protein of the chromaffin granule membrane. J Neurochem (1981) 1.11
Identification of a plasma membrane-associated guanine nucleotide exchange factor for ARF6 in chromaffin cells. Possible role in the regulated exocytotic pathway. J Biol Chem (2000) 1.09
Human apolipoprotein C-I accounts for the ability of plasma high density lipoproteins to inhibit the cholesteryl ester transfer protein activity. J Biol Chem (2000) 1.09
Structural analysis of junctions formed between lipid membranes and several annexins by cryo-electron microscopy. J Mol Biol (1997) 1.08
Intracellular and extracellular processing of chromogranin A. Determination of cleavage sites. Eur J Biochem (1993) 1.08
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Evidence for tubulin-binding sites on cellular membranes: plasma membranes, mitochondrial membranes, and secretory granule membranes. J Cell Biol (1983) 1.07
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Guanine nucleotide exchange on ADP-ribosylation factors catalyzed by cytohesin-1 and its Sec7 domain. J Biol Chem (1998) 1.05
New antimicrobial activity for the catecholamine release-inhibitory peptide from chromogranin A. Cell Mol Life Sci (2005) 1.03
GTP-dependent binding of ADP-ribosylation factor to coatomer in close proximity to the binding site for dilysine retrieval motifs and p23. J Biol Chem (1999) 1.02
Synthesis of beta-hematin by dehydrohalogenation of hemin. Biochem Biophys Res Commun (1993) 1.02
Identification of a potential effector pathway for the trimeric Go protein associated with secretory granules. Go stimulates a granule-bound phosphatidylinositol 4-kinase by activating RhoA in chromaffin cells. J Biol Chem (1998) 1.00
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The ADP ribosylation factor nucleotide exchange factor ARNO promotes beta-arrestin release necessary for luteinizing hormone/choriogonadotropin receptor desensitization. Proc Natl Acad Sci U S A (2000) 1.00
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Freeze-fracture study of the chromaffin cell during exocytosis: evidence for connections between the plasma membrane and secretory granules and for movements of plasma membrane-associated particles. Cell Tissue Res (1979) 0.98
ARF1 controls proliferation of breast cancer cells by regulating the retinoblastoma protein. Oncogene (2011) 0.98
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Functional interaction between matrix metalloproteinase-3 and semaphorin-3C during cortical axonal growth and guidance. Cereb Cortex (2006) 0.96
Interactions of the transcription factor AP-1 with the long terminal repeat of different human immunodeficiency virus type 1 strains in Jurkat, glial, and neuronal cells. J Virol (1995) 0.95
Characterization of a GTPase-activating protein that stimulates GTP hydrolysis by both ADP-ribosylation factor (ARF) and ARF-like proteins. Comparison to the ARD1 gap domain. J Biol Chem (1996) 0.94
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Involvement of ADP-ribosylation factor 1 in cholera toxin-induced morphological changes of Chinese hamster ovary cells. J Biol Chem (2001) 0.93
Implication of neuropilin 2/semaphorin 3F in retinocollicular map formation. Dev Dyn (2008) 0.93