Published in J Biol Chem on February 07, 1997
Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts. J Cell Biol (2000) 4.34
Myosin phosphatase target subunit: Many roles in cell function. Biochem Biophys Res Commun (2007) 2.08
Identification of the endogenous smooth muscle myosin phosphatase-associated kinase. Proc Natl Acad Sci U S A (2001) 1.89
Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2. J Cell Biol (2010) 1.73
Phosphorylation of the myosin phosphatase target subunit by integrin-linked kinase. Biochem J (2002) 1.59
Activation of myosin phosphatase targeting subunit by mitosis-specific phosphorylation. J Cell Biol (1999) 1.26
Myosin light chain kinase and the role of myosin light chain phosphorylation in skeletal muscle. Arch Biochem Biophys (2011) 1.16
Integrin-linked kinase phosphorylates the myosin phosphatase target subunit at the inhibitory site in platelet cytoskeleton. Biochem J (2002) 1.15
Protein phosphatase 1 regulation by inhibitors and targeting subunits. Proc Natl Acad Sci U S A (2001) 1.05
Reconstituted human myosin light chain phosphatase reveals distinct roles of two inhibitory phosphorylation sites of the regulatory subunit, MYPT1. Biochemistry (2014) 0.95
A novel regulatory mechanism of myosin light chain phosphorylation via binding of 14-3-3 to myosin phosphatase. Mol Biol Cell (2007) 0.95
NH2-terminal fragments of the 130 kDa subunit of myosin phosphatase increase the Ca2+ sensitivity of porcine renal artery. J Physiol (1999) 0.92
Identification and localization of myosin phosphatase in human platelets. Biochem J (1998) 0.91
Cloning and identification of MYPT3: a prenylatable myosin targetting subunit of protein phosphatase 1. Biochem J (2001) 0.87
Compressive stress induces dephosphorylation of the myosin regulatory light chain via RhoA phosphorylation by the adenylyl cyclase/protein kinase A signaling pathway. PLoS One (2015) 0.80
Platelet adhesion to collagen activates a phosphoprotein complex of heat-shock proteins and protein phosphatase 1. J Neural Transm (Vienna) (1997) 0.78
Diversity and plasticity in signaling pathways that regulate smooth muscle responsiveness: Paradigms and paradoxes for the myosin phosphatase, the master regulator of smooth muscle contraction. J Smooth Muscle Res (2017) 0.77
Effects of a fluorescent Myosin light chain phosphatase inhibitor on prostate cancer cells. Front Oncol (2011) 0.77
Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts. J Cell Biol (2000) 4.34
Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase. J Biol Chem (1999) 3.55
Phosphorylation of smooth muscle myosin at two distinct sites by myosin light chain kinase. J Biol Chem (1985) 2.45
Modulator protein as a component of the myosin light chain kinase from chicken gizzard. Biochemistry (1978) 2.32
Rho-associated kinase of chicken gizzard smooth muscle. J Biol Chem (1999) 2.10
Fractionation of troponin into two distinct proteins. Biochem Biophys Res Commun (1968) 1.96
Identification of the endogenous smooth muscle myosin phosphatase-associated kinase. Proc Natl Acad Sci U S A (2001) 1.89
Smooth muscle myosin light chain kinase. Methods Enzymol (1983) 1.72
Inhibition of Rho-associated kinase blocks agonist-induced Ca2+ sensitization of myosin phosphorylation and force in guinea-pig ileum. J Physiol (2000) 1.71
Phosphorylation of the large subunit of myosin phosphatase and inhibition of phosphatase activity. J Biol Chem (1996) 1.71
X-ray structure determination of telokin, the C-terminal domain of myosin light chain kinase, at 2.8 A resolution. J Mol Biol (1992) 1.69
Characterization of the myosin-binding subunit of smooth muscle myosin phosphatase. J Biol Chem (1994) 1.67
The contractile proteins of smooth muscle. Properties and components of a Ca2+-sensitive actomyosin from chicken gizzard. Arch Biochem Biophys (1975) 1.64
The preparation of tropomyosin and troponin from natural actomyosin. Biochim Biophys Acta (1969) 1.62
Identification, phosphorylation, and dephosphorylation of a second site for myosin light chain kinase on the 20,000-dalton light chain of smooth muscle myosin. J Biol Chem (1986) 1.62
Phosphorylation of the 20,000-dalton light chain of smooth muscle myosin by the calcium-activated, phospholipid-dependent protein kinase. Phosphorylation sites and effects of phosphorylation. J Biol Chem (1987) 1.60
Roles of calcium and phosphorylation in the regulation of the activity of gizzard myosin. Biochemistry (1978) 1.58
Composition of the myosin light chain kinase from chicken gizzard. Biochem Biophys Res Commun (1977) 1.58
Calcium-sensitive regulation of actin-myosin interactions in baby hamster kidney (BHK-21) cells. Proc Natl Acad Sci U S A (1979) 1.46
Phosphorylation of CPI-17, an inhibitory phosphoprotein of smooth muscle myosin phosphatase, by Rho-kinase. FEBS Lett (2000) 1.44
A Ca2+-and modulator-dependent myosin light chain kinase from non-muscle cells. Biochem Biophys Res Commun (1978) 1.43
The subunit structure of myosin. I. Polydispersity in 5 M guanidine. J Biol Chem (1966) 1.42
Phosphorylation of smooth muscle myosin: evidence for cooperativity between the myosin heads. Science (1981) 1.40
The adeonosine-triphosphatase activity of desensitized actomyosin. Biochem J (1967) 1.39
Proteolysis of smooth muscle myosin light chain kinase. Formation of inactive and calmodulin-independent fragments. J Biol Chem (1987) 1.39
Effects of phosphorylation of light chain residues threonine 18 and serine 19 on the properties and conformation of smooth muscle myosin. J Biol Chem (1988) 1.37
The effect of phosphorylation of gizzard myosin on actin activation. Biochem Biophys Res Commun (1976) 1.37
Dynamic properties of actin. Structural changes induced by beryllium fluoride. J Biol Chem (1994) 1.37
Proteolysis of smooth muscle myosin by Staphylococcus aureus protease: preparation of heavy meromyosin and subfragment 1 with intact 20 000-dalton light chains. Biochemistry (1985) 1.36
Calyculin-A increases the level of protein phosphorylation and changes the shape of 3T3 fibroblasts. Cell Motil Cytoskeleton (1991) 1.35
Effects of Ca2+ on the conformation and enzymatic activity of smooth muscle myosin. J Biol Chem (1985) 1.35
Thiophosphorylation of the 130-kDa subunit is associated with a decreased activity of myosin light chain phosphatase in alpha-toxin-permeabilized smooth muscle. J Biol Chem (1995) 1.33
Regulation of smooth muscle actomyosin. Annu Rev Physiol (1981) 1.31
Effects of modulators of myosin light-chain kinase activity in single smooth muscle cells. Nature (1989) 1.30
Differential localization of myosin and myosin phosphatase subunits in smooth muscle cells and migrating fibroblasts. Mol Biol Cell (1997) 1.30
Correlation of enzymatic properties and conformation of smooth muscle myosin. Biochemistry (1983) 1.29
BHK21 myosin: isolation, biochemical characterization and intracellular localization. J Cell Sci (1978) 1.29
The effect of various protein fractions on Z- and M-line reconstitution. J Cell Biol (1969) 1.26
Activation of myosin phosphatase targeting subunit by mitosis-specific phosphorylation. J Cell Biol (1999) 1.26
Autoregulation of enzymes by pseudosubstrate prototopes: myosin light chain kinase. Science (1988) 1.23
Calcium-independent myosin light chain kinase of smooth muscle. Preparation by limited chymotryptic digestion of the calcium ion dependent enzyme, purification, and characterization. Biochemistry (1982) 1.20
A protein factor inhibiting the magnesium-activated adenosine triphosphatase of desensitized actomyosin. Biochem J (1967) 1.18
Calcium binding by the troponin complex, and the purification and properties of troponin A. Biochim Biophys Acta (1971) 1.16
The effect of tropomyosin on the adenosine triphosphatase activity of desensitized actomyosin. Biochem J (1967) 1.16
Phosphorylation of a twitchin-related protein controls catch and calcium sensitivity of force production in invertebrate smooth muscle. Proc Natl Acad Sci U S A (1998) 1.16
Interactions and properties of smooth muscle myosin phosphatase. Biochemistry (1996) 1.14
Interaction of smooth muscle myosin phosphatase with phospholipids. Biochemistry (1997) 1.13
A relationship between Ca2+ sensitivity and phosphorylation of gizzard actomyosin. Biochem Biophys Res Commun (1976) 1.12
Ordered phosphorylation of the two 20 000 molecular weight light chains of smooth muscle myosin. Biochemistry (1983) 1.11
Phosphorylation of a high molecular weight (approximately 600 kDa) protein regulates catch in invertebrate smooth muscle. J Muscle Res Cell Motil (1997) 1.10
Identification in turkey gizzard of an acidic protein related to the C-terminal portion of smooth muscle myosin light chain kinase. J Biol Chem (1989) 1.08
Studies on troponin. Biochim Biophys Acta (1969) 1.07
The binding of smooth muscle myosin light chain kinase to actin. Biochem Biophys Res Commun (1982) 1.05
Removal and reconstitution of Z-line material in a striated muscle. J Cell Biol (1967) 1.05
Phosphorylation of smooth muscle myosin and myosin light chains. Fed Proc (1980) 1.04
The inhibition of the adenosine triphosphatase activity of the subfragment 1-actin complex by troponin plus tropomoosin, troponin B plus tropomyosin and troponin B. Biochim Biophys Acta (1970) 1.04
A factor inhibiting the adenosine triphosphatase activity and the superprecipitation of actomyosin. Nature (1966) 1.04
Regulation of smooth muscle actomyosin. Blood Vessels (1982) 1.04
Myotonic dystrophy protein kinase phosphorylates the myosin phosphatase targeting subunit and inhibits myosin phosphatase activity. FEBS Lett (2001) 1.03
Interaction of protein phosphatase type 1 with a splicing factor. FEBS Lett (1996) 1.03
Definition of the inhibitory domain of smooth muscle myosin light chain kinase by site-directed mutagenesis. Biochemistry (1991) 1.03
Separation and recombination of the ethylene glycol bis (beta-aminoethyl ether)-N,N'-tetraacetic acid-sensitizing factor obtained from a low ionic strength extract of natural actomyosin. J Biol Chem (1967) 1.02
Phosphorylation-dependent activated tension in skinned gizzard muscle fibers in the absence of Ca2+. J Biol Chem (1982) 1.02
Bovine stomach myosin light chain kinase: purification, characterization, and comparison with the turkey gizzard enzyme. Biochemistry (1982) 1.00
Study of the subunit interactions in myosin phosphatase by surface plasmon resonance. Eur J Biochem (2000) 1.00
A new isoform of human myosin phosphatase targeting/regulatory subunit (MYPT2): cDNA cloning, tissue expression, and chromosomal mapping. Genomics (1998) 1.00
Phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by protein kinase N. Biochem Biophys Res Commun (2000) 0.98
Biochemical basis for contraction of vascular smooth muscle. Chest (1980) 0.98
Gizzard Ca2+-independent myosin light chain kinase: evidence in favor of the phosphorylation theory. Fed Proc (1983) 0.97
A regulatory subunit of smooth muscle myosin bound phosphatase. Biochem Biophys Res Commun (1994) 0.95
Effect of tropomyosin on the calcium-activated adenosine triphosphatase of actomyosin. Nature (1967) 0.95
Intracellular calcium and smooth muscle contraction. Cell Calcium (1986) 0.92
Interaction of the ribosomal protein, L5, with protein phosphatase type 1. J Biol Chem (1995) 0.92
Phosphorylation of molluscan twitchin by the cAMP-dependent protein kinase. Biochemistry (2001) 0.92
Effects of magnesium chloride on smooth muscle actomyosin adenosine-5'-triphosphatase activity, myosin conformation, and tension development in glycerinated smooth muscle fibers. Biochemistry (1984) 0.91
Identification and localization of myosin phosphatase in human platelets. Biochem J (1998) 0.91
Identification of human CPI-17, an inhibitory phosphoprotein for myosin phosphatase. Biochem Biophys Res Commun (2001) 0.91
Changes in the cytoskeleton of 3T3 fibroblasts induced by the phosphatase inhibitor, calyculin-A. J Muscle Res Cell Motil (1992) 0.91
Identification of two forms of myosin light chain kinase in turkey gizzard. FEBS Lett (1983) 0.90
A novel protein phosphatase inhibitor, tautomycin. Effect on smooth muscle. FEBS Lett (1991) 0.90
Conformation-dependent proteolysis of smooth-muscle myosin. J Biol Chem (1984) 0.89
Discovery of a novel series of potent and selective substrate-based inhibitors of p60c-src protein tyrosine kinase: conformational and topographical constraints in peptide design. J Med Chem (1998) 0.89
Arachidonic acid-induced Ca2+ sensitization of smooth muscle contraction through activation of Rho-kinase. Pflugers Arch (2001) 0.89
Interaction of myosin phosphatase target subunit 1 with the catalytic subunit of type 1 protein phosphatase. Biochemistry (1998) 0.89
Phosphorylation of paramyosin. Comp Biochem Physiol B (1989) 0.88
Actin-binding peptide from smooth muscle myosin light chain kinase. Biochemistry (1993) 0.88
Cleavage of a smooth muscle myosin heavy chain near its C terminus by alpha-chymotrypsin. Effect on the properties of myosin. J Biol Chem (1991) 0.87
Effect of phosphorylation on the actin-activated ATPase activity of myosin. Biochem Biophys Res Commun (1981) 0.87
Phosphorylation of caldesmon. FEBS Lett (1989) 0.87
Paramyosin and the catch mechanism. Comp Biochem Physiol B (1990) 0.87
The myosin cross-bridge cycle and its control by twitchin phosphorylation in catch muscle. Biophys J (2001) 0.87
Endothall thioanhydride inhibits protein phosphatases-1 and -2A in vivo. Am J Physiol (1995) 0.87
ATPase activity and superprecipitation of skeletal muscle actomyosin of frog and rabbit: effect of temperature on calcium sensitivity. Comp Biochem Physiol B (1975) 0.86
Phosphorylation of myosin as a regulatory mechanism in smooth muscle. Prog Clin Biol Res (1990) 0.86
Interactions of desensitized actomyosin with tropomyosin, troponin A, troponin B, and polyanions. J Gen Physiol (1970) 0.86
Proteolysis and actin-binding properties of 10S and 6S smooth muscle myosin: identification of a site protected from proteolysis in the 10S conformation and by the binding of actin. Biochemistry (1986) 0.85
Ca2+ and Mg2+ dependent conformations of troponin C as determined by 1H and 19F nuclear magnetic resonance. Biochemistry (1977) 0.85
Phosphorylation of smooth muscle actin by the catalytic subunit of the cAMP-dependent protein kinase. Biochem Biophys Res Commun (1981) 0.85
Changes in the cytoskeletal structure of cultured smooth muscle cells induced by calyculin-A. J Cell Sci (1993) 0.85
Reverse reaction of smooth muscle myosin light chain kinase. Formation of ATP from phosphorylated light chain plus ADP. J Biol Chem (1986) 0.84