Published in Adv Exp Med Biol on January 01, 1996
A centennial history of research on asthma pathogenesis. Am J Respir Cell Mol Biol (2005) 1.72
Botulinum toxin B in the sensory afferent: transmitter release, spinal activation, and pain behavior. Pain (2013) 1.44
Adipose-derived stem cells stimulate regeneration of peripheral nerves: BDNF secreted by these cells promotes nerve healing and axon growth de novo. PLoS One (2011) 1.29
Models of inflammation of the lower urinary tract. Neurourol Urodyn (2011) 1.25
Neutral endopeptidase (EC 3.4.24.11) terminates colitis by degrading substance P. Proc Natl Acad Sci U S A (1999) 1.22
Endothelin-converting enzyme 1 promotes re-sensitization of neurokinin 1 receptor-dependent neurogenic inflammation. Br J Pharmacol (2009) 1.02
Targeting TRPV1 as an alternative approach to narcotic analgesics to treat chronic pain conditions. AAPS J (2010) 1.00
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Activation of peripheral kappa opioid receptors inhibits capsaicin-induced thermal nociception in rhesus monkeys. J Pharmacol Exp Ther (1999) 0.94
Bone marrow transplantation reveals an essential synergy between neuronal and hemopoietic cell neurokinin production in pulmonary inflammation. J Clin Invest (2003) 0.93
Local administration of mu or kappa opioid agonists attenuates capsaicin-induced thermal hyperalgesia via peripheral opioid receptors in rats. Psychopharmacology (Berl) (2000) 0.87
Neutral endopeptidase (EC 3.4.24.11) downregulates the onset of intestinal inflammation in the nematode infected mouse. Gut (2003) 0.86
Translocation of Bax and Bid to mitochondria, endoplasmic reticulum and nuclear envelope: possible control points in apoptosis. J Mol Histol (2004) 0.86
Bronchoconstriction induced by increasing airway temperature in ovalbumin-sensitized rats: role of tachykinins. J Appl Physiol (1985) (2013) 0.86
Significance of Conversation between Mast Cells and Nerves. Allergy Asthma Clin Immunol (2005) 0.81
Nociceptors in cardiovascular functions: complex interplay as a result of cyclooxygenase inhibition. Mol Pain (2006) 0.79
Neprilysin levels in plasma and synovial fluid of juvenile idiopathic arthritis patients. Rheumatol Int (2004) 0.79
Altered Innervation Pattern in Ligaments of Patients with Basal Thumb Arthritis. J Wrist Surg (2015) 0.77
Inflammation-induced abnormalities in the subcellular localization and trafficking of the neurokinin 1 receptor in the enteric nervous system. Am J Physiol Gastrointest Liver Physiol (2015) 0.76
Substance P antagonist CP-96345 blocks lung vascular leakage and inflammation more effectively than its stereoisomer CP-96344 in a mouse model of smoke inhalation and burn injury. Toxicol Mech Methods (2010) 0.75
Openings between defective endothelial cells explain tumor vessel leakiness. Am J Pathol (2000) 5.94
beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2. J Cell Biol (2000) 4.29
Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism. Nat Med (2000) 3.71
Proteinase-activated receptors: novel mechanisms of signaling by serine proteases. Am J Physiol (1998) 3.54
Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway. Nat Med (2001) 3.17
The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta -arrestin-dependent scaffolding complex. Proc Natl Acad Sci U S A (2000) 2.69
Endocytosis of activated TrkA: evidence that nerve growth factor induces formation of signaling endosomes. J Neurosci (1996) 2.65
Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2. Biochem J (1996) 2.55
Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells. Dev Biol (2001) 2.46
Infliximab for the treatment of pyoderma gangrenosum: a randomised, double blind, placebo controlled trial. Gut (2005) 2.36
Tissue-selective mast cell reconstitution and differential lung gene expression in mast cell-deficient Kit(W-sh)/Kit(W-sh) sash mice. Clin Exp Allergy (2005) 2.32
Effects of a cosmetic 'anti-ageing' product improves photoaged skin [corrected]. Br J Dermatol (2009) 2.25
Protease-activated receptors in inflammation, neuronal signaling and pain. Trends Pharmacol Sci (2001) 2.06
Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2. J Clin Invest (1997) 2.04
Agonist-selective endocytosis of mu opioid receptor by neurons in vivo. Proc Natl Acad Sci U S A (1996) 2.03
Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2. Proc Natl Acad Sci U S A (1997) 1.99
Mechanisms of desensitization and resensitization of proteinase-activated receptor-2. J Biol Chem (1996) 1.99
Permeability-related changes revealed at endothelial cell borders in inflamed venules by lectin binding. Am J Physiol (1996) 1.97
T cell gelatinases mediate basement membrane transmigration in vitro. J Immunol (1995) 1.78
Regulatory mechanisms that modulate signalling by G-protein-coupled receptors. Biochem J (1997) 1.77
Cationic liposomes target angiogenic endothelial cells in tumors and chronic inflammation in mice. J Clin Invest (1998) 1.72
Direct observation of substance P-induced internalization of neurokinin 1 (NK1) receptors at sites of inflammation. Proc Natl Acad Sci U S A (1994) 1.72
Angiogenesis in mice with chronic airway inflammation: strain-dependent differences. Am J Pathol (1998) 1.69
Time course of endothelial cell proliferation and microvascular remodeling in chronic inflammation. Am J Pathol (2001) 1.67
Endothelial gaps as sites for plasma leakage in inflammation. Microcirculation (1999) 1.61
Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system. Neurogastroenterol Motil (2010) 1.60
Trypsin activates pancreatic duct epithelial cell ion channels through proteinase-activated receptor-2. J Clin Invest (1999) 1.59
Characterization of antisera specific to NK1, NK2, and NK3 neurokinin receptors and their utilization to localize receptors in the rat gastrointestinal tract. J Neurosci (1996) 1.58
Delineation of the endocytic pathway of substance P and its seven-transmembrane domain NK1 receptor. Mol Biol Cell (1995) 1.52
Proteinase-activated receptor-2 in human skin: tissue distribution and activation of keratinocytes by mast cell tryptase. Exp Dermatol (1999) 1.45
Characterization of antibodies to the rat substance P (NK-1) receptor and to a chimeric substance P receptor expressed in mammalian cells. J Neurosci (1994) 1.40
Symptomatic metastatic pulmonary calcification in a renal transplant recipient. Intern Med J (2013) 1.39
Trafficking of proteinase-activated receptor-2 and beta-arrestin-1 tagged with green fluorescent protein. beta-Arrestin-dependent endocytosis of a proteinase receptor. J Biol Chem (1999) 1.38
Thrombin and mast cell tryptase regulate guinea-pig myenteric neurons through proteinase-activated receptors-1 and -2. J Physiol (1999) 1.31
Role of peripheral N-methyl-D-aspartate (NMDA) receptors in visceral nociception in rats. Gastroenterology (2001) 1.28
Mechanisms of desensitization and resensitization of G protein-coupled neurokinin1 and neurokinin2 receptors. Mol Pharmacol (1996) 1.26
Neutrophils induce damage to respiratory epithelial cells infected with respiratory syncytial virus. Eur Respir J (1998) 1.25
Organ-specific endothelial cell uptake of cationic liposome-DNA complexes in mice. Am J Physiol (1997) 1.25
Presence and bronchomotor activity of protease-activated receptor-2 in guinea pig airways. Am J Respir Crit Care Med (2000) 1.24
Desensitization of the neurokinin-1 receptor (NK1-R) in neurons: effects of substance P on the distribution of NK1-R, Galphaq/11, G-protein receptor kinase-2/3, and beta-arrestin-1/2. Mol Biol Cell (1998) 1.24
Neutral endopeptidase (EC 3.4.24.11) terminates colitis by degrading substance P. Proc Natl Acad Sci U S A (1999) 1.22
Agonist-induced internalization of the substance P (NK1) receptor expressed in epithelial cells. Biochem J (1994) 1.22
Neurokinin 1 receptor internalization in spinal cord slices induced by dorsal root stimulation is mediated by NMDA receptors. J Neurosci (1997) 1.21
Determinants of endothelial cell phenotype in venules. Microcirculation (2000) 1.21
Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism. Br J Pharmacol (2001) 1.18
Endocytosis and recycling of neurokinin 1 receptors in enteric neurons. Neuroscience (1996) 1.15
Cellular sites of expression of the neurokinin-1 receptor in the rat gastrointestinal tract. J Comp Neurol (1995) 1.13
Basolateral proteinase-activated receptor (PAR-2) induces chloride secretion in M-1 mouse renal cortical collecting duct cells. J Physiol (1999) 1.12
Substance P-induced trafficking of beta-arrestins. The role of beta-arrestins in endocytosis of the neurokinin-1 receptor. J Biol Chem (1999) 1.11
Interactions between neutral endopeptidase (EC 3.4.24.11) and the substance P (NK1) receptor expressed in mammalian cells. Biochem J (1994) 1.10
Identification of potential tyrosine-containing endocytic motifs in the carboxyl-tail and seventh transmembrane domain of the neurokinin 1 receptor. J Biol Chem (1997) 1.10
Psychiatric morbidity in patients with chronic airflow obstruction. Med J Aust (1987) 1.10
Protease-activated receptors: how proteases signal to cells. Curr Opin Pharmacol (2001) 1.10
Protease-activated receptors: novel PARtners in innate immunity. Trends Immunol (2007) 1.09
Neuropeptides in the skin: interactions between the neuroendocrine and the skin immune systems. Exp Dermatol (1998) 1.08
Neuropeptide regulation of human dermal microvascular endothelial cell ICAM-1 expression and function. Am J Physiol (1998) 1.05
Acute ACE inhibition causes plasma extravasation in mice that is mediated by bradykinin and substance P. Hypertension (1998) 1.05
Intestinal type 2 proteinase-activated receptors: expression in opioid-sensitive secretomotor neural circuits that mediate epithelial ion transport. J Pharmacol Exp Ther (2000) 1.04
Substance P activates coincident NF-AT- and NF-kappa B-dependent adhesion molecule gene expression in microvascular endothelial cells through intracellular calcium mobilization. J Immunol (1999) 1.03
Neurogenic plasma leakage in mouse airways. Br J Pharmacol (1999) 1.03
Upregulation of substance P receptors in angiogenesis associated with chronic airway inflammation in rats. Am J Physiol (1997) 1.02
The apoptosis of neutrophils is accelerated in respiratory syncytial virus (RSV)-induced bronchiolitis. Clin Exp Immunol (1998) 1.02
Endothelin-converting enzyme 1 promotes re-sensitization of neurokinin 1 receptor-dependent neurogenic inflammation. Br J Pharmacol (2009) 1.02
Calcitonin receptor-like receptor and receptor activity modifying protein 1 in the rat dorsal horn: localization in glutamatergic presynaptic terminals containing opioids and adrenergic alpha2C receptors. Neuroscience (2007) 1.02
Dynamin and Rab5a-dependent trafficking and signaling of the neurokinin 1 receptor. J Biol Chem (2001) 1.01
Turning off the signal: mechanisms that attenuate signaling by G protein-coupled receptors. Am J Physiol (1997) 1.00
Distribution of neurokinin-2 receptors in the guinea-pig gastrointestinal tract. Cell Tissue Res (1996) 0.99
A role for transient receptor potential vanilloid 4 in tonicity-induced neurogenic inflammation. Br J Pharmacol (2010) 0.99
Glucocorticoid-induced apoptosis of dendritic cells in the rat tracheal mucosa. Am J Respir Cell Mol Biol (1998) 0.99
Substance P mediates inflammatory oedema in acute pancreatitis via activation of the neurokinin-1 receptor in rats and mice. Br J Pharmacol (2000) 0.98
A signaling endosome hypothesis to explain NGF actions: potential implications for neurodegeneration. Cold Spring Harb Symp Quant Biol (1996) 0.98
VCAM-1 expression on human dermal microvascular endothelial cells is directly and specifically up-regulated by substance P. J Immunol (1999) 0.98
Substance P release in the dorsal horn assessed by receptor internalization: NMDA receptors counteract a tonic inhibition by GABA(B) receptors. Eur J Neurosci (1999) 0.98
Neutral endopeptidase terminates substance P-induced inflammation in allergic contact dermatitis. J Immunol (2001) 0.96
Stimulation of the neurokinin 3 receptor activates protein kinase C epsilon and protein kinase D in enteric neurons. Am J Physiol Gastrointest Liver Physiol (2008) 0.95
Direct observation of endocytosis of gastrin releasing peptide and its receptor. J Biol Chem (1995) 0.94
Catabolism of calcitonin gene-related peptide and substance P by neutral endopeptidase. Peptides (1991) 0.92
Deletion of neutral endopeptidase exacerbates intestinal inflammation induced by Clostridium difficile toxin A. Am J Physiol Gastrointest Liver Physiol (2001) 0.92
Location of focal silver staining at endothelial gaps in inflamed venules examined by scanning electron microscopy. Am J Physiol (1995) 0.92
Agonist-mediated endocytosis of rat somatostatin receptor subtype 3 involves beta-arrestin and clathrin coated vesicles. J Neuroendocrinol (2001) 0.91
Substance P induction of murine keratinocyte PAM 212 interleukin 1 production is mediated by the neurokinin 2 receptor (NK-2R). Exp Dermatol (2000) 0.91
GPBA: a GPCR for bile acids and an emerging therapeutic target for disorders of digestion and sensation. Br J Pharmacol (2014) 0.91
Airway vasculature after mycoplasma infection: chronic leakiness and selective hypersensitivity to substance P. Am J Physiol Lung Cell Mol Physiol (2001) 0.90
Activation and internalization of the mu-opioid receptor by the newly discovered endogenous agonists, endomorphin-1 and endomorphin-2. Neuroscience (1999) 0.90
Agonists of proteinase-activated receptor 2 excite guinea pig ileal myenteric neurons. Eur J Pharmacol (2001) 0.90
Downregulation of neutral endopeptidase (EC 3.4.24.11) in the inflamed rat intestine. Am J Physiol (1993) 0.89
Expression and function of proteinase-activated receptor 2 in human bronchial smooth muscle. Am J Respir Crit Care Med (2001) 0.89
Expression of protease activated receptor-2 (PAR-2) in central airways of smokers and non-smokers. Thorax (2002) 0.89
Substance P (NK1) receptor immunoreactivity on endothelial cells of the rat tracheal mucosa. Am J Physiol (1996) 0.89
Neurokinin 1 receptor distribution in cholinergic neurons and targets of substance P terminals in the rat nucleus accumbens. J Comp Neurol (2000) 0.88
The conserved NPXnY motif present in the gastrin-releasing peptide receptor is not a general sequestration sequence. J Biol Chem (1994) 0.88
Adhesion molecule expression on epithelial cells infected with respiratory syncytial virus. Eur Respir J (2000) 0.88
Neutral endopeptidase expression and distribution in human skin and wounds. J Invest Dermatol (1999) 0.88
Interactions of the skin and nervous system. J Investig Dermatol Symp Proc (1997) 0.88
Repair of photoaged dermal matrix by topical application of a cosmetic 'antiageing' product. Br J Dermatol (2007) 0.87
Neutral endopeptidase (EC 3.4.24.11) downregulates the onset of intestinal inflammation in the nematode infected mouse. Gut (2003) 0.86