The crystal structure of a triacylglycerol lipase from Pseudomonas cepacia reveals a highly open conformation in the absence of a bound inhibitor.

PubWeight™: 1.22‹?› | Rank: Top 10%

🔗 View Article (PMID 9032073)

Published in Structure on February 15, 1997

Authors

K K Kim1, H K Song, D H Shin, K Y Hwang, S W Suh

Author Affiliations

1: Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-742, Korea.

Articles citing this

Bacterial lipolytic enzymes: classification and properties. Biochem J (1999) 4.92

Crystal structure of the ribosome recycling factor from Escherichia coli. EMBO J (2000) 1.35

Exogenously triggered, enzymatic degradation of photopolymerized hydrogels with polycaprolactone subunits: experimental observation and modeling of mass loss behavior. Biomacromolecules (2006) 1.21

Dieselzymes: development of a stable and methanol tolerant lipase for biodiesel production by directed evolution. Biotechnol Biofuels (2013) 0.98

Modeling of solvent-dependent conformational transitions in Burkholderia cepacia lipase. BMC Struct Biol (2009) 0.90

Isolation and characterization of a new alkali-thermostable lipase cloned from a metagenomic library. J Ind Microbiol Biotechnol (2009) 0.87

In vitro analysis of roles of a disulfide bridge and a calcium binding site in activation of Pseudomonas sp. strain KWI-56 lipase. J Bacteriol (2000) 0.86

Enzyme-nanoporous gold biocomposite: excellent biocatalyst with improved biocatalytic performance and stability. PLoS One (2011) 0.84

Acinetobacter lipases: molecular biology, biochemical properties and biotechnological potential. J Ind Microbiol Biotechnol (2004) 0.84

Purification, characterization, and molecular cloning of organic-solvent-tolerant cholesterol esterase from cyclohexane-tolerant Burkholderia cepacia strain ST-200. Extremophiles (2006) 0.83

Helicobacter pylori EstV: identification, cloning, and characterization of the first lipase isolated from an epsilon-proteobacterium. Appl Environ Microbiol (2007) 0.81

Large scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis. J Biol Chem (2013) 0.80

Lipase and its modulator from Pseudomonas sp. strain KFCC 10818: proline-to-glutamine substitution at position 112 induces formation of enzymatically active lipase in the absence of the modulator. J Bacteriol (2001) 0.78

A membrane-bound esterase PA2949 from Pseudomonas aeruginosa is expressed and purified from Escherichia coli. FEBS Open Bio (2016) 0.76

Crystal structure of Proteus mirabilis lipase, a novel lipase from the Proteus/psychrophilic subfamily of lipase family I.1. PLoS One (2012) 0.76

Mining bacterial genomes for novel arylesterase activity. Microb Biotechnol (2010) 0.76

Crystallization and preliminary crystallographic analysis of LipC12, a true lipase isolated through a metagenomics approach. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.75

Characterization of Pythium Transcriptome and Gene Expression Analysis at Different Stages of Fermentation. PLoS One (2013) 0.75

The Lid Domain in Lipases: Structural and Functional Determinant of Enzymatic Properties. Front Bioeng Biotechnol (2017) 0.75

Cell-bound lipases from Burkholderia sp. ZYB002: gene sequence analysis, expression, enzymatic characterization, and 3D structural model. BMC Biotechnol (2016) 0.75

Efficient biocatalyst by encapsulating lipase into nanoporous gold. Nanoscale Res Lett (2013) 0.75

Effects of i-propanol on the structural dynamics of Thermomyces lanuginosa lipase revealed by tryptophan fluorescence. Protein Sci (2001) 0.75

Articles by these authors

The structures of HsIU and the ATP-dependent protease HsIU-HsIV. Nature (2000) 4.46

The role of zinc in selective neuronal death after transient global cerebral ischemia. Science (1996) 2.99

Q-switched 532-nm Nd:YAG laser trabeculoplasty (selective laser trabeculoplasty): a multicenter, pilot, clinical study. Ophthalmology (1998) 2.85

Endobronchial tuberculosis. Clinical and bronchoscopic features in 121 cases. Chest (1992) 2.83

Crystal structure of Thermus aquaticus DNA polymerase. Nature (1995) 2.62

Importance of zinc in the central nervous system: the zinc-containing neuron. J Nutr (2000) 2.16

Risk factors for retinal vein occlusions. A case-control study. Ophthalmology (1992) 2.06

Tertiary structure of plant RuBisCO: domains and their contacts. Science (1988) 2.06

Patterns of status epilepticus-induced neuronal injury during development and long-term consequences. J Neurosci (1998) 1.83

Blockade of cannabinoid receptor 1 improves insulin resistance, lipid metabolism, and diabetic nephropathy in db/db mice. Endocrinology (2012) 1.81

Digital topological analysis of in vivo magnetic resonance microimages of trabecular bone reveals structural implications of osteoporosis. J Bone Miner Res (2001) 1.80

Crystal structure of NAD(+)-dependent DNA ligase: modular architecture and functional implications. EMBO J (2000) 1.78

MRI measurement of brain iron in patients with restless legs syndrome. Neurology (2001) 1.75

Comparison of the Tono-Pen to the Goldmann applanation tonometer. Arch Ophthalmol (1988) 1.68

Roles of the catalytic domain and two cellulose binding domains of Thermomonospora fusca E4 in cellulose hydrolysis. J Bacteriol (1998) 1.65

I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice. J Immunol (1999) 1.56

The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology. Tuberculosis (Edinb) (2003) 1.55

Age-related decline of disc rim area in visually normal subjects. Ophthalmology (1992) 1.55

Oestrogen receptor B-region polymorphism and spontaneous abortion in women with breast cancer. Lancet (1990) 1.49

Rapid translocation of Zn(2+) from presynaptic terminals into postsynaptic hippocampal neurons after physiological stimulation. J Neurophysiol (2001) 1.49

Associations of blood lead, dimercaptosuccinic acid-chelatable lead, and tibia lead with neurobehavioral test scores in South Korean lead workers. Am J Epidemiol (2001) 1.46

Purification and characterization of the heat shock proteins HslV and HslU that form a new ATP-dependent protease in Escherichia coli. J Biol Chem (1996) 1.46

Structural and mechanistic conservation in DNA ligases. Nucleic Acids Res (2000) 1.44

Is it worthwhile to add dipivefrin HCl 0.1% to topical beta 1-, beta 2-blocker therapy? Ophthalmology (1989) 1.44

Effect of ribosomes on the biosynthesis of ribonucleic acid in vitro. J Mol Biol (1966) 1.44

Past pregnancy is associated with axillary node involvement in women with breast cancer. Cancer (1992) 1.42

Cancellous bone volume and structure in the forearm: noninvasive assessment with MR microimaging and image processing. Radiology (1998) 1.42

Adjunctive viscoelastic therapy for postoperative ciliary block. Ophthalmic Surg (1992) 1.40

Comparative study of silicone versus acrylic foldable lens implantation in primary glaucoma triple procedure. Ophthalmology (1997) 1.38

High-resolution crystal structure of the non-specific lipid-transfer protein from maize seedlings. Structure (1995) 1.37

Kunitz-type soybean trypsin inhibitor revisited: refined structure of its complex with porcine trypsin reveals an insight into the interaction between a homologous inhibitor from Erythrina caffra and tissue-type plasminogen activator. J Mol Biol (1998) 1.36

Crystal structure of the ribosome recycling factor from Escherichia coli. EMBO J (2000) 1.35

Crystal structure of Escherichia coli CyaY protein reveals a previously unidentified fold for the evolutionarily conserved frataxin family. Proc Natl Acad Sci U S A (2000) 1.34

Reproducibility and error sources of micro-MRI-based trabecular bone structural parameters of the distal radius and tibia. Bone (2004) 1.32

Malignant colorectal obstruction: treatment with a flexible covered stent. Radiology (1998) 1.32

Pattern of publication of ophthalmic abstracts in peer-reviewed journals. Ophthalmology (1991) 1.29

Crystal structure of carboxylesterase from Pseudomonas fluorescens, an alpha/beta hydrolase with broad substrate specificity. Structure (1997) 1.29

Fast 3D large-angle spin-echo imaging (3D FLASE). Magn Reson Med (1996) 1.29

Spectrum of opportunistic infections and malignancies in patients with human immunodeficiency virus infection in South Korea. Clin Infect Dis (1999) 1.26

Malignant obstruction of gastric outlet and duodenum: palliation with flexible covered metallic stents. Radiology (2001) 1.25

Structural basis of non-specific lipid binding in maize lipid-transfer protein complexes revealed by high-resolution X-ray crystallography. J Mol Biol (2001) 1.24

Family history in primary open-angle glaucoma. Arch Ophthalmol (1977) 1.24

Cross-sectional study of osteopenia with quantitative MR imaging and bone densitometry. Radiology (2000) 1.23

Measurement of phosphorus content in normal and osteomalacic rabbit bone by solid-state 3D radial imaging. Magn Reson Med (2006) 1.22

Isolation, characterization, and functional analysis of a novel cDNA clone encoding a small rubber particle protein from Hevea brasiliensis. J Biol Chem (1999) 1.22

A noncontact, nondestructive method for quantifying intratissue deformations and strains. J Biomech Eng (2002) 1.21

RAGE regulates BACE1 and Abeta generation via NFAT1 activation in Alzheimer's disease animal model. FASEB J (2009) 1.21

Topological analysis of trabecular bone MR images. IEEE Trans Med Imaging (2000) 1.20

Absence of 185delAG mutation of the BRCA1 gene and 6174delT mutation of the BRCA2 gene in Ashkenazi Jewish men with prostate cancer. Br J Cancer (1998) 1.16

In vivo MR micro imaging with conventional radiofrequency coils cooled to 77 degrees K. Magn Reson Med (2000) 1.14

Adjunctive mitomycin C in primary trabeculectomy in phakic eyes. Am J Ophthalmol (1995) 1.14

Extraovarian granulosa cell tumor. Yonsei Med J (2001) 1.14

Trigger digits in children. J Hand Surg Br (2001) 1.13

Electrophoretic karyotype analysis of sequential Candida parapsilosis isolates from patients with persistent or pecurrent fungemia. J Clin Microbiol (2001) 1.12

Vibrio vulnificus has the transmembrane transcription activator ToxRS stimulating the expression of the hemolysin gene vvhA. J Bacteriol (2000) 1.12

Use of a real time continuous glucose monitoring system as a motivational device for poorly controlled type 2 diabetes. Diabetes Res Clin Pract (2008) 1.12

Microbiologic aspects of predominant bacteria isolated from the burn patients in Korea. Burns (2001) 1.12

Whatever happened to abstracts from different sections of the association for research in vision and ophthalmology? Invest Ophthalmol Vis Sci (1993) 1.11

Sliding-layer conformational change limited by the quaternary structure of plant RuBisCO. Nature (1987) 1.11

Mitomycin and the human corneal endothelium. Arch Ophthalmol (1994) 1.09

Measurement of R'2 in the presence of multiple spectral components using reference spectrum deconvolution. J Magn Reson (1998) 1.09

Structural basis for cold adaptation. Sequence, biochemical properties, and crystal structure of malate dehydrogenase from a psychrophile Aquaspirillium arcticum. J Biol Chem (1999) 1.08

Comparison of ADA and WHO criteria for the diagnosis of diabetes in elderly Koreans. Diabet Med (2002) 1.07

Nosocomial cluster of Candida lipolytica fungemia in pediatric patients. Eur J Clin Microbiol Infect Dis (2000) 1.07

High-speed spectroscopic imaging for cancellous bone marrow R(2)* mapping and lipid quantification. Magn Reson Imaging (2000) 1.06

Contralateral effect of topical beta-adrenergic antagonists in initial one-eyed trials in the ocular hypertension treatment study. Am J Ophthalmol (2000) 1.06

Rice non-specific lipid transfer protein: the 1.6 A crystal structure in the unliganded state reveals a small hydrophobic cavity. J Mol Biol (1998) 1.06

Multi-modality study of the compositional and mechanical implications of hypomineralization in a rabbit model of osteomalacia. Bone (2007) 1.05

Associations between laboratory parameters and outcome of paraquat poisoning. Toxicol Lett (2000) 1.04

Endoscopic factors predisposing to rebleeding following endoscopic hemostasis in bleeding peptic ulcers. Endoscopy (2001) 1.03

Impaired CD4 T cell activation due to reliance upon B cell-mediated costimulation in nonobese diabetic (NOD) mice. J Immunol (2000) 1.03

Retained cellulose sponge after trabeculectomy with adjunctive subconjunctival mitomycin C. Am J Ophthalmol (1994) 1.03

The stimulation of RNA synthesis by ribosomes in vitro. Biochem Biophys Res Commun (1966) 1.02

Cyclin D1 overexpression is an indicator of poor prognosis in resectable non-small cell lung cancer. Br J Cancer (1999) 1.02

Visual field global indices in patients with reversal of glaucomatous cupping after intraocular pressure reduction. Ophthalmology (1991) 1.02

Molecular cloning of carp (Cyprinus carpio) CC chemokine, CXC chemokine receptors, allograft inflammatory factor-1, and natural killer cell enhancing factor by use of suppression subtractive hybridization. Immunogenetics (1999) 1.02

Crystal structure and functional analysis of the SurE protein identify a novel phosphatase family. Nat Struct Biol (2001) 1.01

Posterior capsular opacification in phacotrabeculectomy : a long-term comparative study of silicone versus acrylic intraocular lens. Ophthalmology (2000) 1.00

Impaired activation of islet-reactive CD4 T cells in pancreatic lymph nodes of B cell-deficient nonobese diabetic mice. J Immunol (2001) 1.00

MR appearance of distal femoral cortical irregularity (cortical desmoid). J Comput Assist Tomogr (1996) 0.99

Risk factors for early filtration failure requiring suture release after primary glaucoma triple procedure with adjunctive mitomycin. Arch Ophthalmol (1999) 0.99

Corneal endothelial cell counts after Molteno implantation. Am J Ophthalmol (1993) 0.99

Misuse of eye drops due to interchanged caps. Arch Ophthalmol (1988) 0.99

Insights into eukaryotic multistep phosphorelay signal transduction revealed by the crystal structure of Ypd1p from Saccharomyces cerevisiae. J Mol Biol (1999) 0.99

Parkinsonism as an initial manifestation of dural arteriovenous fistula. Eur J Neurol (2005) 0.98

Idiopathic bronchiolitis obliterans with organizing pneumonia presenting with spontaneous hydropneumothorax and solitary pulmonary nodule. Respirology (1999) 0.97

Development of genu varum in achondroplasia: relation to fibular overgrowth. J Bone Joint Surg Br (2007) 0.97

The heat-shock protein HslVU from Escherichia coli is a protein-activated ATPase as well as an ATP-dependent proteinase. Eur J Biochem (1997) 0.97

Crystal structures of thermostable xylose isomerases from Thermus caldophilus and Thermus thermophilus: possible structural determinants of thermostability. J Mol Biol (1999) 0.96

Structure of ribulose-1,5-bisphosphate carboxylase-oxygenase: Form III crystals. Proc Natl Acad Sci U S A (1977) 0.96