Published in J Clin Invest on March 15, 1997
PTH-independent regulation of blood calcium concentration by the calcium-sensing receptor. J Clin Invest (2012) 2.61
Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia. J Clin Invest (2005) 2.14
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5. J Clin Invest (2003) 2.09
Physiology and pathophysiology of the calcium-sensing receptor in the kidney. Am J Physiol Renal Physiol (2009) 2.02
The calcium-sensing receptor promotes urinary acidification to prevent nephrolithiasis. J Am Soc Nephrol (2009) 1.85
The epithelial sodium/proton exchanger, NHE3, is necessary for renal and intestinal calcium (re)absorption. Am J Physiol Renal Physiol (2011) 1.66
Calcimimetic inhibits late-stage cyst growth in ADPKD. J Am Soc Nephrol (2009) 1.58
Calcium-sensing receptor abrogates secretagogue- induced increases in intestinal net fluid secretion by enhancing cyclic nucleotide destruction. Proc Natl Acad Sci U S A (2006) 1.48
Hypercalcaemic and hypocalcaemic conditions due to calcium-sensing receptor mutations. Best Pract Res Clin Rheumatol (2008) 1.44
Regulated acid-base transport in the collecting duct. Pflugers Arch (2009) 1.42
Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption. Pflugers Arch (2008) 1.37
Demographic, dietary, and urinary factors and 24-h urinary calcium excretion. Clin J Am Soc Nephrol (2009) 1.25
Calcium-sensing receptor attenuates AVP-induced aquaporin-2 expression via a calmodulin-dependent mechanism. J Am Soc Nephrol (2007) 1.17
Thick ascending limb: the Na(+):K (+):2Cl (-) co-transporter, NKCC2, and the calcium-sensing receptor, CaSR. Pflugers Arch (2008) 1.12
Polyvalent cation receptor proteins (CaRs) are salinity sensors in fish. Proc Natl Acad Sci U S A (2002) 1.10
The calcium-sensing receptor and calcimimetics in blood pressure modulation. Br J Pharmacol (2011) 1.01
Expression and insights on function of potassium channel TWIK-1 in mouse kidney. Pflugers Arch (2005) 1.00
Mechanisms of multimodal sensing by extracellular Ca(2+)-sensing receptors: a domain-based survey of requirements for binding and signalling. Br J Pharmacol (2010) 1.00
Aquaporin-2 regulation in health and disease. Vet Clin Pathol (2012) 0.98
A test of the hypothesis that the collecting duct calcium-sensing receptor limits rise of urine calcium molarity in hypercalciuric calcium kidney stone formers. Am J Physiol Renal Physiol (2009) 0.98
Cell biology of vasopressin-regulated aquaporin-2 trafficking. Pflugers Arch (2012) 0.97
Salt and acid-base metabolism in claudin-16 knockdown mice: impact for the pathophysiology of FHHNC patients. Am J Physiol Renal Physiol (2008) 0.95
Effect of calcium-sensing receptor activation in models of autosomal recessive or dominant polycystic kidney disease. Nephrol Dial Transplant (2008) 0.92
Calcium-sensing receptor inhibits secretagogue-induced electrolyte secretion by intestine via the enteric nervous system. Am J Physiol Gastrointest Liver Physiol (2012) 0.92
Calcium-sensing receptor and aquaporin 2 interplay in hypercalciuria-associated renal concentrating defect in humans. An in vivo and in vitro study. PLoS One (2012) 0.90
Calcium-sensing receptor 20 years later. Am J Physiol Cell Physiol (2014) 0.87
Asymmetrical, agonist-induced fluctuations in local extracellular [Ca(2+)] in intact polarized epithelia. EMBO J (2001) 0.87
Epithelial CaSR deficiency alters intestinal integrity and promotes proinflammatory immune responses. FEBS Lett (2014) 0.86
Increased biological response to 1,25(OH)(2)D(3) in genetic hypercalciuric stone-forming rats. Am J Physiol Renal Physiol (2013) 0.86
Ca2+-sensing receptor-mediated regulation of volume-sensitive Cl- channels in human epithelial cells. J Physiol (2000) 0.85
Localization and function of the renal calcium-sensing receptor. Nat Rev Nephrol (2016) 0.83
Calcium-sensing receptor signaling pathways in medullary thick ascending limb cells mediate COX-2-derived PGE2 production: functional significance. Am J Physiol Renal Physiol (2008) 0.82
A novel therapeutic effect of statins on nephrogenic diabetes insipidus. J Cell Mol Med (2015) 0.81
Calcium-sensing receptor stimulates Cl(-)- and SCFA-dependent but inhibits cAMP-dependent HCO3(-) secretion in colon. Am J Physiol Gastrointest Liver Physiol (2015) 0.80
Comparative expression of the extracellular calcium-sensing receptor in the mouse, rat, and human kidney. Am J Physiol Renal Physiol (2015) 0.80
Calcium-sensing receptor: A new target for therapy of diarrhea. World J Gastroenterol (2016) 0.80
Detection of renal tissue and urinary tract proteins in the human urine after space flight. PLoS One (2013) 0.78
Coupling of epithelial Na+ and Cl- channels by direct and indirect activation by serine proteases. Am J Physiol Cell Physiol (2012) 0.78
Tumor necrosis factor-alpha induces renal cyclooxygenase-2 expression in response to hypercalcemia. Prostaglandins Other Lipid Mediat (2012) 0.77
pH-sensitive expression of calcium-sensing receptor (CaSR) in type-B intercalated cells of the cortical collecting ducts (CCD) in mouse kidney. Clin Exp Nephrol (2014) 0.77
Vitamin D increases plasma renin activity independently of plasma Ca2+ via hypovolemia and β-adrenergic activity. Am J Physiol Renal Physiol (2013) 0.76
Cytoskeletal changes induced by allosteric modulators of calcium-sensing receptor in esophageal epithelial cells. Physiol Rep (2015) 0.76
Urinary concentration: different ways to open and close the tap. Pediatr Nephrol (2013) 0.75
Extracellular zinc stimulates a calcium-activated chloride conductance through mobilisation of intracellular calcium in renal inner medullary collecting duct cells. Pflugers Arch (2006) 0.75
Role of the Vasopressin/Apelin Balance and Potential Use of Metabolically Stable Apelin Analogs in Water Metabolism Disorders. Front Endocrinol (Lausanne) (2017) 0.75
Vitamin D Toxicity in Young Breastfed Infants: Report of 2 Cases. Glob Pediatr Health (2017) 0.75
Modulation of aquaporin 2 expression in the kidney of young goats by changes in nitrogen intake. J Comp Physiol B (2014) 0.75
Calcium and calcimimetics regulate paracellular Na+ transport in the thin ascending limb of Henle's loop in mouse kidney. Pflugers Arch (2010) 0.75
Cloning and expression of apical membrane water channel of rat kidney collecting tubule. Nature (1993) 4.99
Phosphoinositides as regulators in membrane traffic. Science (1996) 4.13
Mutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Cell (1993) 4.13
Protein kinase C isoenzymes: divergence in signal transduction? Biochem J (1993) 3.86
Cellular and subcellular immunolocalization of vasopressin-regulated water channel in rat kidney. Proc Natl Acad Sci U S A (1993) 3.82
The urinary excretion of calcium and inorganic phosphate in 344 patients with calcium stone of renal origin. Br J Surg (1958) 3.11
Renal stone epidemiology: a 25-year study in Rochester, Minnesota. Kidney Int (1979) 2.79
Molecular cloning and expression of a member of the aquaporin family with permeability to glycerol and urea in addition to water expressed at the basolateral membrane of kidney collecting duct cells. Proc Natl Acad Sci U S A (1994) 2.54
Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes. Proc Natl Acad Sci U S A (1995) 2.37
Autosomal dominant hypocalcaemia caused by a Ca(2+)-sensing receptor gene mutation. Nat Genet (1994) 2.23
Vasopressin effects on urea and H2O transport in inner medullary collecting duct subsegments. Am J Physiol (1987) 2.17
Molecular cloning and functional expression of human parathyroid calcium receptor cDNAs. J Biol Chem (1995) 1.86
Calcium and cyclic adenosine monophosphate as second messengers for vasopressin in the rat inner medullary collecting duct. J Clin Invest (1988) 1.78
Water permeability of apical and basolateral cell membranes of rat inner medullary collecting duct. Am J Physiol (1990) 1.65
Cloning and functional expression of a rat kidney extracellular calcium/polyvalent cation-sensing receptor. Proc Natl Acad Sci U S A (1995) 1.61
Identification and localization of an actin-binding motif that is unique to the epsilon isoform of protein kinase C and participates in the regulation of synaptic function. J Cell Biol (1996) 1.48
Vasopressin- and cAMP-induced changes in ultrastructure of isolated perfused inner medullary collecting ducts. Am J Physiol (1993) 1.47
Calcium-ion-sensing cell-surface receptors. N Engl J Med (1995) 1.35
Expression of VAMP-2-like protein in kidney collecting duct intracellular vesicles. Colocalization with Aquaporin-2 water channels. J Clin Invest (1995) 1.15
Factors that predict relapse of calcium nephrolithiasis during treatment: a prospective study. Am J Med (1982) 1.15
Ontogeny of the extracellular calcium-sensing receptor in rat kidney. Am J Physiol (1996) 1.11
Control of magnesium transport in the thick ascending limb. Am J Physiol (1989) 1.07
Characterization of purified endosomes containing the antidiuretic hormone-sensitive water channel from rat renal papilla. J Biol Chem (1994) 1.06
Hormonal signaling and regulation of salt and water transport in the collecting duct. Annu Rev Physiol (1994) 1.05
Maximal urine-concentrating ability: familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. J Clin Endocrinol Metab (1981) 1.03
Morphologic heterogeneity along the rat inner medullary collecting duct. Lab Invest (1989) 1.02
Purified epithelial Na+ channel complex contains the pertussis toxin-sensitive G alpha i-3 protein. J Biol Chem (1992) 0.98
Guanine nucleotide binding regulatory proteins and adenylate cyclase in livers of streptozotocin- and BB/Wor-diabetic rats. Immunodetection of Gs and Gi with antisera prepared against synthetic peptides. J Clin Invest (1989) 0.98
Inhibitory guanosine triphosphate-binding protein-mediated regulation of vasopressin action in isolated single medullary tubules of mouse kidney. J Clin Invest (1988) 0.96
Mechanism of concentrating defect in hypercalcemia. Role of polydipsia and prostaglandins. Kidney Int (1983) 0.96
Rat kidney papilla contains abundant synaptobrevin protein that participates in the fusion of antidiuretic hormone-regulated water channel-containing endosomes in vitro. Proc Natl Acad Sci U S A (1995) 0.93
Expression of G protein alpha-subunits in bovine parathyroid. Endocrinology (1995) 0.90
Acidification of serotonin-containing secretory vesicles induced by a plasma membrane calcium receptor. J Biol Chem (1996) 0.84
Distribution and role of heterotrimeric G proteins in the secretory pathway of polarized epithelial cells. J Cell Sci Suppl (1993) 0.84
Hormone signaling systems in inner medullary collecting ducts. Am J Physiol (1992) 0.81
Luminal calcium regulates potassium transport by the renal distal tubule. Am J Physiol (1990) 0.80
Polycations reduce vasopressin-induced water flow by endocytic removal of water channels. Am J Physiol (1986) 0.78
Urinary ionic calcium and binding sites in normocalciuric idiopathic calcium urolithiasis. Invest Urol (1979) 0.78
Water channel vesicles from toad urinary bladder contain a family of proteins present in other tissues. Am J Physiol (1994) 0.78
Epidemiological investigation of urolithiasis in Israel. J Urol (1959) 0.77
Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer. Lancet (2005) 11.05
Psychological outcomes of different treatment policies in women with early breast cancer outside a clinical trial. BMJ (1990) 10.93
Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid. Nature (1993) 7.89
First results from the International Breast Cancer Intervention Study (IBIS-I): a randomised prevention trial. Lancet (2002) 6.02
Cloning and expression of an inwardly rectifying ATP-regulated potassium channel. Nature (1993) 5.69
Effects of breast conservation on psychological morbidity associated with diagnosis and treatment of early breast cancer. Br Med J (Clin Res Ed) (1986) 5.37
High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells. Diabetes (2000) 4.55
Evaluation of quality of life in patients receiving treatment for advanced breast cancer. Lancet (1976) 4.53
Cause-specific mortality in long-term survivors of breast cancer who participated in trials of radiotherapy. J Clin Oncol (1994) 4.50
Mutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Cell (1993) 4.13
Cellular and subcellular immunolocalization of vasopressin-regulated water channel in rat kidney. Proc Natl Acad Sci U S A (1993) 3.82
Psychological effects of being offered choice of surgery for breast cancer. BMJ (1994) 3.48
A familial syndrome of hypocalcemia with hypercalciuria due to mutations in the calcium-sensing receptor. N Engl J Med (1996) 3.20
A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Nat Genet (1995) 3.18
Do we need informed consent? Lancet (1986) 3.02
Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney. J Biol Chem (1994) 2.89
Can magnetic-resonance imaging help elucidate natural history of breast cancer multicentricity? Lancet (1998) 2.70
Breast cancer, desmoid tumours, and familial adenomatous polyposis--a unifying hypothesis. Lancet (1993) 2.69
Diagnosis of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop. J Clin Endocrinol Metab (2009) 2.69
Primary management of carcinoma of the breast. Lancet (1993) 2.59
Screening for breast cancer, time to think--and stop? Lancet (1995) 2.58
Results of a program to reduce admissions for adult asthma. Ann Intern Med (1990) 2.51
Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells. Proc Natl Acad Sci U S A (1989) 2.48
Structural organization and functional analysis of centromeric DNA in the fission yeast Schizosaccharomyces pombe. Mol Cell Biol (1988) 2.37
Overview of randomized trials of postoperative adjuvant radiotherapy in breast cancer. Cancer Treat Rep (1987) 2.37
Clinical syndromes of mastalgia. Lancet (1976) 2.35
Mass screening for cancer of the breast. Lancet (1968) 2.33
Reduced immunostaining for the extracellular Ca2+-sensing receptor in primary and uremic secondary hyperparathyroidism. J Clin Endocrinol Metab (1996) 2.33
Distribution of transcellular calcium and sodium transport pathways along mouse distal nephron. Am J Physiol Renal Physiol (2001) 2.28
Expression of the Na-K-2Cl cotransporter is developmentally regulated in postnatal rat brains: a possible mechanism underlying GABA's excitatory role in immature brain. J Neurobiol (1997) 2.24
Autosomal dominant hypocalcaemia caused by a Ca(2+)-sensing receptor gene mutation. Nat Genet (1994) 2.23
Maxi-K channels contribute to urinary potassium excretion in the ROMK-deficient mouse model of Type II Bartter's syndrome and in adaptation to a high-K diet. Kidney Int (2006) 2.22
Is clinical breast examination an acceptable alternative to mammographic screening? BMJ (2000) 2.18
Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis. Pharmacogenomics J (2007) 2.17
Polycystin-L is a calcium-regulated cation channel permeable to calcium ions. Nature (1999) 2.17
Molecular cloning and characterization of a channel-like transporter mediating intestinal calcium absorption. J Biol Chem (1999) 2.16
Primary structure and functional expression of a cDNA encoding the thiazide-sensitive, electroneutral sodium-chloride cotransporter. Proc Natl Acad Sci U S A (1993) 2.15
Oestrogen as a reticuloendothelial stimulant in patients with cancer. Br Med J (1971) 2.14
Can results from clinical trials be generalized? Nat Med (1995) 2.13
Expression of an extracellular calcium-sensing receptor in human and mouse bone marrow cells. J Bone Miner Res (1997) 2.11
Time to abandon TNM staging of breast cancer? Lancet (1992) 2.05
L-amino acid sensing by the extracellular Ca2+-sensing receptor. Proc Natl Acad Sci U S A (2000) 2.02
Dimerization of the extracellular calcium-sensing receptor (CaR) on the cell surface of CaR-transfected HEK293 cells. J Biol Chem (1998) 1.98
Molecular cloning and functional expression of human parathyroid calcium receptor cDNAs. J Biol Chem (1995) 1.86
Human herpesvirus type 8 DNA sequences in cell-free plasma and mononuclear cells of Kaposi's sarcoma patients. J Infect Dis (1996) 1.85
Benefit from adjuvant tamoxifen therapy in primary breast cancer patients according oestrogen receptor, progesterone receptor, EGF receptor and HER2 status. Ann Oncol (2006) 1.85
What are the psychological factors influencing attendance, non-attendance and re-attendance at a breast screening centre? J R Soc Med (1990) 1.83
A new biological framework for cancer research. Lancet (1996) 1.73
Control of NaCl transport in the thick ascending limb. Am J Physiol (1984) 1.72
Changes over time in socioeconomic inequalities in breast and rectal cancer survival in England and Wales during a 32-year period (1973-2004): the potential role of health care. Ann Oncol (2011) 1.72
The ORION statement: guidelines for transparent reporting of outbreak reports and intervention studies of nosocomial infection. J Antimicrob Chemother (2007) 1.72
ROMK inwardly rectifying ATP-sensitive K+ channel. II. Cloning and distribution of alternative forms. Am J Physiol (1995) 1.72
Induction of transforming growth factor beta 1 in human breast cancer in vivo following tamoxifen treatment. Cancer Res (1992) 1.71
Familial hypercalcemia and hypercalciuria caused by a novel mutation in the cytoplasmic tail of the calcium receptor. J Clin Endocrinol Metab (2000) 1.71
Organization of clinical trial on national scale: management of early cancer of the breast. Br Med J (1972) 1.70
Reticulo-endothelial activity in humans with cancer. Br J Surg (1970) 1.69
Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator. Proc Natl Acad Sci U S A (1996) 1.69
Intercellular communication mediated by the extracellular calcium-sensing receptor. Nat Cell Biol (2000) 1.68
Angiotensin II type 2 receptor mediates vascular smooth muscle cell apoptosis in cystic medial degeneration associated with Marfan's syndrome. Circulation (2001) 1.63
Localization of the extracellular Ca2+/polyvalent cation-sensing protein in rat kidney. Am J Physiol (1998) 1.62
Cloning and functional expression of a rat kidney extracellular calcium/polyvalent cation-sensing receptor. Proc Natl Acad Sci U S A (1995) 1.61
Improved survival among patients treated with adjuvant tamoxifen after mastectomy for early breast cancer. Lancet (1983) 1.61
Do psychological studies upset patients? J R Soc Med (1987) 1.60
Clostridium difficile in acute and long-stay elderly patients. Age Ageing (1988) 1.60
Should lymphadenectomy be discarded? I. Immunological considerations. J R Coll Surg Edinb (1973) 1.60
Expression and characterization of inactivating and activating mutations in the human Ca2+o-sensing receptor. J Biol Chem (1996) 1.59
Renal K+ channels: structure and function. Annu Rev Physiol (1997) 1.59
The effects of surgery on tumor growth: a century of investigations. Ann Oncol (2008) 1.59
Postoperative radiotherapy and late mortality: evidence from the Cancer Research Campaign trial for early breast cancer. BMJ (1989) 1.59
Effect of mithramycin on calcium and hydroxyproline metabolism in patients with malignant disease. Br Med J (1967) 1.58
Effect of prenatal dexamethasone on rat renal development. Kidney Int (2001) 1.58
Contralateral renal abnormalities in multicystic-dysplastic kidney disease. J Pediatr (1992) 1.57
Putting the risk of breast cancer in perspective. BMJ (1998) 1.56
Nomenclature of the proteins of cows' milk--sixth revision. J Dairy Sci (2004) 1.55
Comparative trial of endocrine versus cytotoxic treatment in advanced breast cancer. Br Med J (1977) 1.55
Calcium-regulated renal calcium handling in healthy men: relationship to sodium handling. J Clin Endocrinol Metab (1998) 1.55
Molecular cloning and chromosome localization of a putative basolateral Na(+)-K(+)-2Cl- cotransporter from mouse inner medullary collecting duct (mIMCD-3) cells. J Biol Chem (1994) 1.54
Localization of the thiazide sensitive Na-Cl cotransporter, rTSC1 in the rat kidney. Kidney Int (1996) 1.54
Cell membranes impermeable to NH3. Nature (1989) 1.54
Tamoxifen and contralateral breast cancer. Lancet (1985) 1.53
False positive findings of mammography will have psychological consequences. BMJ (1996) 1.51
Localization of the ROMK protein on apical membranes of rat kidney nephron segments. Am J Physiol (1997) 1.50
Does surgery disseminate or accelerate cancer? Lancet (1996) 1.50
Importance of mastalgia in operable breast cancer. Br Med J (Clin Res Ed) (1982) 1.49
The trials of Dr. Bernard Fisher: a European perspective on an American episode. Control Clin Trials (1997) 1.49
Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons. Proc Natl Acad Sci U S A (1996) 1.49
Anti-oestrogens induce the secretion of active transforming growth factor beta from human fetal fibroblasts. Br J Cancer (1990) 1.48
Polycystin-2 is a novel cation channel implicated in defective intracellular Ca(2+) homeostasis in polycystic kidney disease. Biochem Biophys Res Commun (2001) 1.48
The hypronosticon test in breast cancer. Clin Oncol (1975) 1.47
Addressing the psychological needs of the conservatively treated breast cancer patient: discussion paper. J R Soc Med (1987) 1.46
Regulation of ROMK1 K+ channel activity involves phosphorylation processes. Proc Natl Acad Sci U S A (1994) 1.46
Rationalism versus irrationalism in the care of the sick: science versus the absurd. Med J Aust (1990) 1.46