Published in Proc Natl Acad Sci U S A on July 01, 2002
Calcium-sensing receptor abrogates secretagogue- induced increases in intestinal net fluid secretion by enhancing cyclic nucleotide destruction. Proc Natl Acad Sci U S A (2006) 1.48
Identification of acidic residues in the extracellular loops of the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+ and a positive allosteric modulator. J Biol Chem (2002) 1.00
Calcium as an extracellular signalling molecule: perspectives on the Calcium Sensing Receptor in the brain. C R Biol (2005) 1.00
Evolution and origin of vomeronasal-type odorant receptor gene repertoire in fishes. BMC Evol Biol (2006) 0.94
Calcium-sensing receptor inhibits secretagogue-induced electrolyte secretion by intestine via the enteric nervous system. Am J Physiol Gastrointest Liver Physiol (2012) 0.92
Presynaptic external calcium signaling involves the calcium-sensing receptor in neocortical nerve terminals. PLoS One (2010) 0.90
Calcium-sensing receptor 20 years later. Am J Physiol Cell Physiol (2014) 0.87
Role of calcium and other trace elements in the gastrointestinal physiology. World J Gastroenterol (2006) 0.87
Epithelial CaSR deficiency alters intestinal integrity and promotes proinflammatory immune responses. FEBS Lett (2014) 0.86
Calcium-sensing receptor and calcium kidney stones. J Transl Med (2011) 0.86
Localization and function of the renal calcium-sensing receptor. Nat Rev Nephrol (2016) 0.83
Freshwater elasmobranchs: a review of their physiology and biochemistry. J Comp Physiol B (2010) 0.83
Novel regulatory aspects of the extracellular Ca2+-sensing receptor, CaR. Pflugers Arch (2009) 0.81
The corpuscles of Stannius, calcium-sensing receptor, and stanniocalcin: responses to calcimimetics and physiological challenges. Endocrinology (2009) 0.81
Calcium-sensing receptor stimulates Cl(-)- and SCFA-dependent but inhibits cAMP-dependent HCO3(-) secretion in colon. Am J Physiol Gastrointest Liver Physiol (2015) 0.80
Calcium-sensing receptor: A new target for therapy of diarrhea. World J Gastroenterol (2016) 0.80
Footprints of directional selection in wild Atlantic salmon populations: evidence for parasite-driven evolution? PLoS One (2014) 0.78
Genomic arrangement of salinity tolerance QTLs in salmonids: a comparative analysis of Atlantic salmon (Salmo salar) with Arctic charr (Salvelinus alpinus) and rainbow trout (Oncorhynchus mykiss). BMC Genomics (2012) 0.78
Involvement of the calcium-sensing receptor in calcium homeostasis in larval zebrafish exposed to low environmental calcium. Am J Physiol Regul Integr Comp Physiol (2013) 0.77
The Extracellular Calcium-Sensing Receptor in the Intestine: Evidence for Regulation of Colonic Absorption, Secretion, Motility, and Immunity. Front Physiol (2016) 0.76
Molecular Basis of the Extracellular Ligands Mediated Signaling by the Calcium Sensing Receptor. Front Physiol (2016) 0.76
NFAT5 genes are part of the osmotic regulatory system in Atlantic salmon (Salmo salar). Mar Genomics (2016) 0.76
Calcimimetics--fooling the calcium receptor. Pediatr Nephrol (2004) 0.75
Profile of Steven C. Hebert. Proc Natl Acad Sci U S A (2006) 0.75
Ocean acidification alters temperature and salinity preferences in larval fish. Oecologia (2016) 0.75
Primary structure and functional expression of a cDNA encoding the thiazide-sensitive, electroneutral sodium-chloride cotransporter. Proc Natl Acad Sci U S A (1993) 2.15
Localization of the extracellular Ca2+/polyvalent cation-sensing protein in rat kidney. Am J Physiol (1998) 1.62
Cloning and functional expression of a rat kidney extracellular calcium/polyvalent cation-sensing receptor. Proc Natl Acad Sci U S A (1995) 1.61
Expression and characterization of inactivating and activating mutations in the human Ca2+o-sensing receptor. J Biol Chem (1996) 1.59
Apical extracellular calcium/polyvalent cation-sensing receptor regulates vasopressin-elicited water permeability in rat kidney inner medullary collecting duct. J Clin Invest (1997) 1.59
Calcium-ion-sensing cell-surface receptors. N Engl J Med (1995) 1.35
Identification and localization of extracellular Ca(2+)-sensing receptor in rat intestine. Am J Physiol (1998) 1.33
The chloride cell: structure and function in the gills of freshwater fishes. Annu Rev Physiol (1997) 1.25
Sodium and ionic strength sensing by the calcium receptor. J Biol Chem (1998) 1.17
The stomach divalent ion-sensing receptor scar is a modulator of gastric acid secretion. J Biol Chem (2001) 1.07
Putative pheromone receptors related to the Ca2+-sensing receptor in Fugu. Proc Natl Acad Sci U S A (1998) 1.04
Disulfide bonds in the extracellular calcium-polyvalent cation-sensing receptor correlate with dimer formation and its response to divalent cations in vitro. J Biol Chem (1998) 1.03
Water and ion transport by the urinary bladder of the teleost Pseudopleuronectes americanus. Am J Physiol (1975) 0.96
Effects of environmental salinity on Na(+)/K(+)-ATPase in the gills and rectal gland of a euryhaline elasmobranch (Dasyatis sabina). J Exp Biol (2000) 0.90
Time-course changes in the expression of Na+, K+-ATPase in gills and pyloric caeca of brown trout (Salmo trutta) during acclimation to seawater. Physiol Biochem Zool (2000) 0.89
Evidence for calcium-sensing receptor mediated stanniocalcin secretion in fish. Mol Cell Endocrinol (2002) 0.88
Localization of calcium receptor mRNA in the adult rat central nervous system by in situ hybridization. Brain Res (1997) 0.88
Identification and functional assay of an extracellular calcium-sensing receptor in Necturus gastric mucosa. Am J Physiol (1997) 0.88
Olfactory sensitivity to changes in environmental [Ca(2+)] in the marine teleost Sparus aurata. J Exp Biol (2000) 0.84
Ion and water transport by the flounder urinary bladder: salinity dependence. Am J Physiol (1984) 0.81
Recent insights into the coordinate regulation of body water and divalent mineral ion metabolism. Am J Med Sci (1998) 0.79
Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer. Lancet (2005) 11.05
Psychological outcomes of different treatment policies in women with early breast cancer outside a clinical trial. BMJ (1990) 10.93
Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice. Science (2001) 8.53
Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid. Nature (1993) 7.89
First results from the International Breast Cancer Intervention Study (IBIS-I): a randomised prevention trial. Lancet (2002) 6.02
Cloning and expression of an inwardly rectifying ATP-regulated potassium channel. Nature (1993) 5.69
Effects of breast conservation on psychological morbidity associated with diagnosis and treatment of early breast cancer. Br Med J (Clin Res Ed) (1986) 5.37
Evaluation of quality of life in patients receiving treatment for advanced breast cancer. Lancet (1976) 4.53
Cause-specific mortality in long-term survivors of breast cancer who participated in trials of radiotherapy. J Clin Oncol (1994) 4.50
Mutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Cell (1993) 4.13
Cellular and subcellular immunolocalization of vasopressin-regulated water channel in rat kidney. Proc Natl Acad Sci U S A (1993) 3.82
Psychological effects of being offered choice of surgery for breast cancer. BMJ (1994) 3.48
A familial syndrome of hypocalcemia with hypercalciuria due to mutations in the calcium-sensing receptor. N Engl J Med (1996) 3.20
A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Nat Genet (1995) 3.18
Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function. Development (1998) 3.07
Do we need informed consent? Lancet (1986) 3.02
Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney. J Biol Chem (1994) 2.89
Can magnetic-resonance imaging help elucidate natural history of breast cancer multicentricity? Lancet (1998) 2.70
Breast cancer, desmoid tumours, and familial adenomatous polyposis--a unifying hypothesis. Lancet (1993) 2.69
Diagnosis of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop. J Clin Endocrinol Metab (2009) 2.69
Primary management of carcinoma of the breast. Lancet (1993) 2.59
Screening for breast cancer, time to think--and stop? Lancet (1995) 2.58
Results of a program to reduce admissions for adult asthma. Ann Intern Med (1990) 2.51
Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells. Proc Natl Acad Sci U S A (1989) 2.48
Structural organization and functional analysis of centromeric DNA in the fission yeast Schizosaccharomyces pombe. Mol Cell Biol (1988) 2.37
Overview of randomized trials of postoperative adjuvant radiotherapy in breast cancer. Cancer Treat Rep (1987) 2.37
Clinical syndromes of mastalgia. Lancet (1976) 2.35
Mass screening for cancer of the breast. Lancet (1968) 2.33
Reduced immunostaining for the extracellular Ca2+-sensing receptor in primary and uremic secondary hyperparathyroidism. J Clin Endocrinol Metab (1996) 2.33
Distribution of transcellular calcium and sodium transport pathways along mouse distal nephron. Am J Physiol Renal Physiol (2001) 2.28
Expression of the Na-K-2Cl cotransporter is developmentally regulated in postnatal rat brains: a possible mechanism underlying GABA's excitatory role in immature brain. J Neurobiol (1997) 2.24
Autosomal dominant hypocalcaemia caused by a Ca(2+)-sensing receptor gene mutation. Nat Genet (1994) 2.23
Maxi-K channels contribute to urinary potassium excretion in the ROMK-deficient mouse model of Type II Bartter's syndrome and in adaptation to a high-K diet. Kidney Int (2006) 2.22
Is clinical breast examination an acceptable alternative to mammographic screening? BMJ (2000) 2.18
Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis. Pharmacogenomics J (2007) 2.17
Polycystin-L is a calcium-regulated cation channel permeable to calcium ions. Nature (1999) 2.17
Molecular cloning and characterization of a channel-like transporter mediating intestinal calcium absorption. J Biol Chem (1999) 2.16
Primary structure and functional expression of a cDNA encoding the thiazide-sensitive, electroneutral sodium-chloride cotransporter. Proc Natl Acad Sci U S A (1993) 2.15
Oestrogen as a reticuloendothelial stimulant in patients with cancer. Br Med J (1971) 2.14
Can results from clinical trials be generalized? Nat Med (1995) 2.13
Expression of an extracellular calcium-sensing receptor in human and mouse bone marrow cells. J Bone Miner Res (1997) 2.11
Time to abandon TNM staging of breast cancer? Lancet (1992) 2.05
L-amino acid sensing by the extracellular Ca2+-sensing receptor. Proc Natl Acad Sci U S A (2000) 2.02
Dimerization of the extracellular calcium-sensing receptor (CaR) on the cell surface of CaR-transfected HEK293 cells. J Biol Chem (1998) 1.98
Air quality improvement estimation and assessment using contingent valuation method, a case study in Beijing. Environ Monit Assess (2006) 1.96
Molecular cloning and functional expression of human parathyroid calcium receptor cDNAs. J Biol Chem (1995) 1.86
Human herpesvirus type 8 DNA sequences in cell-free plasma and mononuclear cells of Kaposi's sarcoma patients. J Infect Dis (1996) 1.85
Benefit from adjuvant tamoxifen therapy in primary breast cancer patients according oestrogen receptor, progesterone receptor, EGF receptor and HER2 status. Ann Oncol (2006) 1.85
What are the psychological factors influencing attendance, non-attendance and re-attendance at a breast screening centre? J R Soc Med (1990) 1.83
Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetes. J Am Soc Nephrol (2001) 1.75
A new biological framework for cancer research. Lancet (1996) 1.73
Control of NaCl transport in the thick ascending limb. Am J Physiol (1984) 1.72
Changes over time in socioeconomic inequalities in breast and rectal cancer survival in England and Wales during a 32-year period (1973-2004): the potential role of health care. Ann Oncol (2011) 1.72
The ORION statement: guidelines for transparent reporting of outbreak reports and intervention studies of nosocomial infection. J Antimicrob Chemother (2007) 1.72
ROMK inwardly rectifying ATP-sensitive K+ channel. II. Cloning and distribution of alternative forms. Am J Physiol (1995) 1.72
Induction of transforming growth factor beta 1 in human breast cancer in vivo following tamoxifen treatment. Cancer Res (1992) 1.71
Familial hypercalcemia and hypercalciuria caused by a novel mutation in the cytoplasmic tail of the calcium receptor. J Clin Endocrinol Metab (2000) 1.71
Ignition of calcium sparks in arterial and cardiac muscle through caveolae. Circ Res (2000) 1.71
Organization of clinical trial on national scale: management of early cancer of the breast. Br Med J (1972) 1.70
Reticulo-endothelial activity in humans with cancer. Br J Surg (1970) 1.69
Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator. Proc Natl Acad Sci U S A (1996) 1.69
Intercellular communication mediated by the extracellular calcium-sensing receptor. Nat Cell Biol (2000) 1.68
Localization of the extracellular Ca2+/polyvalent cation-sensing protein in rat kidney. Am J Physiol (1998) 1.62
Cloning and functional expression of a rat kidney extracellular calcium/polyvalent cation-sensing receptor. Proc Natl Acad Sci U S A (1995) 1.61
Improved survival among patients treated with adjuvant tamoxifen after mastectomy for early breast cancer. Lancet (1983) 1.61
Do psychological studies upset patients? J R Soc Med (1987) 1.60
Clostridium difficile in acute and long-stay elderly patients. Age Ageing (1988) 1.60
Should lymphadenectomy be discarded? I. Immunological considerations. J R Coll Surg Edinb (1973) 1.60
Expression and characterization of inactivating and activating mutations in the human Ca2+o-sensing receptor. J Biol Chem (1996) 1.59
The effects of surgery on tumor growth: a century of investigations. Ann Oncol (2008) 1.59
Postoperative radiotherapy and late mortality: evidence from the Cancer Research Campaign trial for early breast cancer. BMJ (1989) 1.59
Renal K+ channels: structure and function. Annu Rev Physiol (1997) 1.59
Apical extracellular calcium/polyvalent cation-sensing receptor regulates vasopressin-elicited water permeability in rat kidney inner medullary collecting duct. J Clin Invest (1997) 1.59
Effect of mithramycin on calcium and hydroxyproline metabolism in patients with malignant disease. Br Med J (1967) 1.58
Rapid rise in incidence of Irish paediatric inflammatory bowel disease. Arch Dis Child (2012) 1.58
Effect of prenatal dexamethasone on rat renal development. Kidney Int (2001) 1.58
Contralateral renal abnormalities in multicystic-dysplastic kidney disease. J Pediatr (1992) 1.57
Circulating levels of IL-6 and TNF-α are associated with knee radiographic osteoarthritis and knee cartilage loss in older adults. Osteoarthritis Cartilage (2010) 1.57
Putting the risk of breast cancer in perspective. BMJ (1998) 1.56
Nomenclature of the proteins of cows' milk--sixth revision. J Dairy Sci (2004) 1.55
Calcium-regulated renal calcium handling in healthy men: relationship to sodium handling. J Clin Endocrinol Metab (1998) 1.55
Comparative trial of endocrine versus cytotoxic treatment in advanced breast cancer. Br Med J (1977) 1.55
Molecular cloning and chromosome localization of a putative basolateral Na(+)-K(+)-2Cl- cotransporter from mouse inner medullary collecting duct (mIMCD-3) cells. J Biol Chem (1994) 1.54
Localization of the thiazide sensitive Na-Cl cotransporter, rTSC1 in the rat kidney. Kidney Int (1996) 1.54
Cell membranes impermeable to NH3. Nature (1989) 1.54