| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Antiphospholipid antibodies: anticardiolipin and the lupus anticoagulant in systemic lupus erythematosus (SLE) and in non-SLE disorders. Prevalence and clinical significance.
|
Ann Intern Med
|
1990
|
3.35
|
|
2
|
The membrane glycoprotein Ia-IIa (VLA-2) complex mediates the Mg++-dependent adhesion of platelets to collagen.
|
J Cell Biol
|
1989
|
2.44
|
|
3
|
Alteration of collagen-dependent adhesion, motility, and morphogenesis by the expression of antisense alpha 2 integrin mRNA in mammary cells.
|
J Cell Sci
|
1995
|
2.39
|
|
4
|
Identification of a 160,000 dalton platelet membrane protein that mediates the initial divalent cation-dependent adhesion of platelets to collagen.
|
Cell
|
1986
|
2.38
|
|
5
|
Altered integrin expression and the malignant phenotype: the contribution of multiple integrated integrin receptors.
|
J Mammary Gland Biol Neoplasia
|
1998
|
2.30
|
|
6
|
A monoclonal antibody against human thrombospondin inhibits platelet aggregation.
|
Proc Natl Acad Sci U S A
|
1985
|
2.04
|
|
7
|
Isolation and characterization of a heparin-binding domain from the amino terminus of platelet thrombospondin.
|
J Biol Chem
|
1984
|
1.94
|
|
8
|
The platelet glycoprotein thrombospondin binds specifically to sulfated glycolipids.
|
J Biol Chem
|
1985
|
1.90
|
|
9
|
Inhibition of platelet adhesion to fibronectin, fibrinogen, and von Willebrand factor substrates by a synthetic tetrapeptide derived from the cell-binding domain of fibronectin.
|
Blood
|
1985
|
1.87
|
|
10
|
Decreased expression of integrin adhesive protein receptors in adenocarcinoma of the breast.
|
Am J Pathol
|
1990
|
1.82
|
|
11
|
The impact of heparin concentration and activated clotting time monitoring on blood conservation. A prospective, randomized evaluation in patients undergoing cardiac operation.
|
J Thorac Cardiovasc Surg
|
1995
|
1.80
|
|
12
|
Re-expression of the alpha 2 beta 1 integrin abrogates the malignant phenotype of breast carcinoma cells.
|
Proc Natl Acad Sci U S A
|
1995
|
1.80
|
|
13
|
Identification of a tetrapeptide recognition sequence for the alpha 2 beta 1 integrin in collagen.
|
J Biol Chem
|
1991
|
1.79
|
|
14
|
Mapping of epitopes for monoclonal antibodies against human platelet thrombospondin with electron microscopy and high sensitivity amino acid sequencing.
|
J Cell Biol
|
1985
|
1.62
|
|
15
|
Widespread histologic distribution of the alpha 2 beta 1 integrin cell-surface collagen receptor.
|
Am J Pathol
|
1990
|
1.48
|
|
16
|
Pro-collagenase-1 (matrix metalloproteinase-1) binds the alpha(2)beta(1) integrin upon release from keratinocytes migrating on type I collagen.
|
J Biol Chem
|
2001
|
1.46
|
|
17
|
Decorin binds near the C terminus of type I collagen.
|
J Biol Chem
|
2000
|
1.40
|
|
18
|
The spatial and temporal expression of the alpha 2 beta 1 integrin and its ligands, collagen I, collagen IV, and laminin, suggest important roles in mouse mammary morphogenesis.
|
Differentiation
|
1995
|
1.38
|
|
19
|
Localization of the hemagglutinating activity of platelet thrombospondin to a 140 000-dalton thermolytic fragment.
|
Biochemistry
|
1984
|
1.33
|
|
20
|
Competition for related but nonidentical binding sites on the glycoprotein IIb-IIIa complex by peptides derived from platelet adhesive proteins.
|
Cell
|
1987
|
1.30
|
|
21
|
Activated platelets express IL-1 activity.
|
J Immunol
|
1989
|
1.24
|
|
22
|
alpha 2 integrin subunit cytoplasmic domain-dependent cellular migration requires p38 MAPK.
|
J Biol Chem
|
2000
|
1.22
|
|
23
|
Effects of anti-thrombospondin monoclonal antibodies on the agglutination of erythrocytes and fixed, activated platelets by purified thrombospondin.
|
Biochemistry
|
1985
|
1.21
|
|
24
|
Isolation of the fibrinogen-binding region of platelet thrombospondin.
|
Biochem Biophys Res Commun
|
1984
|
1.17
|
|
25
|
Collagen receptor control of epithelial morphogenesis and cell cycle progression.
|
Am J Pathol
|
1999
|
1.16
|
|
26
|
The alpha 2 beta 1 integrin cell surface collagen receptor binds to the alpha 1 (I)-CB3 peptide of collagen.
|
J Biol Chem
|
1990
|
1.16
|
|
27
|
Prospective evaluation and clinical utility of on-site monitoring of coagulation in patients undergoing cardiac operation.
|
J Thorac Cardiovasc Surg
|
1994
|
1.16
|
|
28
|
Altered integrin expression in adenocarcinoma of the breast. Analysis by in situ hybridization.
|
Am J Pathol
|
1993
|
1.15
|
|
29
|
Ligand recognition by the I domain-containing integrins.
|
Cell Mol Life Sci
|
1998
|
1.14
|
|
30
|
Induced cell surface expression of functional alpha 2 beta 1 integrin during megakaryocytic differentiation of K562 leukemic cells.
|
Exp Cell Res
|
1992
|
1.14
|
|
31
|
Loss of MDCK cell alpha 2 beta 1 integrin expression results in reduced cyst formation, failure of hepatocyte growth factor/scatter factor-induced branching morphogenesis, and increased apoptosis.
|
J Cell Sci
|
1995
|
1.10
|
|
32
|
A three-dimensional collagen lattice activates NF-kappaB in human fibroblasts: role in integrin alpha2 gene expression and tissue remodeling.
|
J Cell Biol
|
1998
|
1.09
|
|
33
|
ERK and p38 MAP kinase pathways are mediators of intestinal epithelial wound-induced signal transduction.
|
Biochem Biophys Res Commun
|
1997
|
1.09
|
|
34
|
Inhibition of platelet aggregation by a monoclonal antibody against human fibronectin.
|
Proc Natl Acad Sci U S A
|
1985
|
1.06
|
|
35
|
Comparison of activated coagulation time and whole blood heparin measurements with laboratory plasma anti-Xa heparin concentration in patients having cardiac operations.
|
J Thorac Cardiovasc Surg
|
1994
|
1.06
|
|
36
|
Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development.
|
Dev Dyn
|
1994
|
1.02
|
|
37
|
The human alpha 2 integrin gene promoter. Identification of positive and negative regulatory elements important for cell-type and developmentally restricted gene expression.
|
J Biol Chem
|
1994
|
1.02
|
|
38
|
Adsorption of von Willebrand factor by fibrillar collagen--implications concerning the adhesion of platelets to collagen.
|
Coll Relat Res
|
1982
|
1.01
|
|
39
|
Specific residues within the alpha 2 integrin subunit cytoplasmic domain regulate migration and cell cycle progression via distinct MAPK pathways.
|
J Biol Chem
|
2001
|
0.99
|
|
40
|
Fibronectin and the multiple interaction model for platelet-collagen adhesion.
|
Proc Natl Acad Sci U S A
|
1979
|
0.98
|
|
41
|
Bone matrix constituents stimulate interleukin-1 release from human blood mononuclear cells.
|
J Clin Invest
|
1991
|
0.97
|
|
42
|
More effective suppression of hemostatic system activation in patients undergoing cardiac surgery by heparin dosing based on heparin blood concentrations rather than ACT.
|
Thromb Haemost
|
1996
|
0.97
|
|
43
|
Isolation and characterization of thrombospondin.
|
Methods Enzymol
|
1987
|
0.96
|
|
44
|
Determinants of ligand binding specificity of the alpha(1)beta(1) and alpha(2)beta(1) integrins.
|
J Biol Chem
|
1999
|
0.95
|
|
45
|
Collagen-mediated platelet aggregation. Evidence for multivalent interactions of intermediate specificity between collagen and platelets.
|
J Clin Invest
|
1977
|
0.94
|
|
46
|
Downstream events in mammary gland morphogenesis mediated by reexpression of the alpha2beta1 integrin: the role of the alpha6 and beta4 integrin subunits.
|
Cancer Res
|
1998
|
0.94
|
|
47
|
Inhibition of platelet aggregation by fibronectin.
|
Biochem Biophys Res Commun
|
1983
|
0.93
|
|
48
|
Adsorption of von Willebrand factor/factor VIII by the genetically distinct interstitial collagens.
|
Thromb Res
|
1981
|
0.93
|
|
49
|
Collagen-induced release of interleukin 1 from human blood mononuclear cells. Potentiation by fibronectin binding to the alpha 5 beta 1 integrin.
|
J Clin Invest
|
1992
|
0.92
|
|
50
|
PDGF induction of alpha 2 integrin gene expression is mediated by protein kinase C-zeta.
|
J Cell Biol
|
1996
|
0.91
|
|
51
|
Mammary epithelial cell-cycle progression via the alpha(2)beta(1) integrin: unique and synergistic roles of the alpha(2) cytoplasmic domain.
|
Am J Pathol
|
2001
|
0.91
|
|
52
|
Characterization of the platelet agglutinating activity of thrombospondin.
|
Biochemistry
|
1985
|
0.90
|
|
53
|
Structural analysis of the alpha(2) integrin I domain/procollagenase-1 (matrix metalloproteinase-1) interaction.
|
J Biol Chem
|
2001
|
0.90
|
|
54
|
Antiphospholipid antibodies and thrombotic predisposition: underlying pathogenetic mechanisms.
|
Blood
|
1994
|
0.90
|
|
55
|
Differential expression of integrin alpha subunits supports distinct roles during lung branching morphogenesis.
|
Dev Dyn
|
1996
|
0.89
|
|
56
|
Contributions of the I and EF hand domains to the divalent cation-dependent collagen binding activity of the alpha2beta1 integrin.
|
J Biol Chem
|
1997
|
0.89
|
|
57
|
Transcriptional regulation of alpha IIb integrin gene expression during megakaryocytic differentiation of K562 cells. Role of a silencer element.
|
J Biol Chem
|
1994
|
0.87
|
|
58
|
Differential regulation of the alpha 2 beta 1 and alpha IIb beta 3 integrin genes during megakaryocytic differentiation of pluripotential K562 cells.
|
J Biol Chem
|
1992
|
0.86
|
|
59
|
Collagen-mediated platelet aggregation: the role of multiple interactions between the platelet surface and collagen.
|
Thromb Haemost
|
1980
|
0.86
|
|
60
|
The ups and downs of alpha 2 beta 1-integrin expression: contributions to epithelial cell differentiation and the malignant phenotype.
|
Curr Top Microbiol Immunol
|
1998
|
0.83
|
|
61
|
Evaluation of complete blood count results from a new, on-site hemocytometer compared with a laboratory-based hemocytometer.
|
Crit Care Med
|
1996
|
0.82
|
|
62
|
Integrins and the kidney: biology and pathobiology.
|
Curr Opin Nephrol Hypertens
|
1999
|
0.82
|
|
63
|
Immunolocalization of alpha-integrin subunits and extracellular matrix components during human colonic organogenesis.
|
Gastroenterology
|
1996
|
0.80
|
|
64
|
Interactions of exercise, coagulation, platelets, and fibrinolysis--a brief review.
|
Med Sci Sports Exerc
|
1988
|
0.80
|
|
65
|
Preferential binding of high molecular weight forms of von Willebrand factor to fibrillar collagen.
|
Biochim Biophys Acta
|
1983
|
0.80
|
|
66
|
Monitoring activity of fibrinolytic agents. A therapeutic challenge.
|
Am J Med
|
1984
|
0.79
|
|
67
|
Whole blood heparin concentration measurements by automated protamine titration agree with plasma anti-Xa measurements.
|
J Thorac Cardiovasc Surg
|
1997
|
0.79
|
|
68
|
Binding of the alpha 2 integrin I domain to extracellular matrix ligands: structural and mechanistic differences between collagen and laminin binding.
|
Cell Adhes Commun
|
1998
|
0.78
|
|
69
|
Relative importance of thrombin compared with plasmin-mediated platelet activation in response to plasminogen activation with streptokinase.
|
Circulation
|
1991
|
0.78
|
|
70
|
Platelet-collagen adhesion-membrane fluidity and the development of high affinity adhesion through multiple interacting sites.
|
Coll Relat Res
|
1981
|
0.77
|
|
71
|
Platelet-collagen adhesion.
|
Methods Enzymol
|
1982
|
0.77
|
|
72
|
In vitro reversal of heparin effect with heparinase: evaluation with whole blood prothrombin time and activated partial thromboplastin time in cardiac surgical patients.
|
Anesth Analg
|
1994
|
0.77
|
|
73
|
Echoviruses 1 and 8 are closely related genetically, and bind to similar determinants within the VLA-2 I domain.
|
Virus Res
|
2001
|
0.77
|
|
74
|
Thrombin enhanced adhesion of platelets to von Willebrand factor substrates.
|
Thromb Res
|
1986
|
0.77
|
|
75
|
Evaluation of a new point-of-care test that measures PAF-mediated acceleration of coagulation in cardiac surgical patients.
|
Anesthesiology
|
1996
|
0.77
|
|
76
|
Role of the alpha1 and alpha2 integrin cytoplasmic domains in cell morphology, motility and responsiveness to stimulation by the protein kinase C pathway.
|
Cell Adhes Commun
|
2000
|
0.77
|
|
77
|
Differential effects of concanavalin A and succinyl concanavalin A on the macromolecular events of platelet activation.
|
Biochim Biophys Acta
|
1983
|
0.77
|
|
78
|
New RGD analogue inhibits human platelet adhesion and aggregation and eliminates platelet deposition on canine vascular grafts.
|
J Vasc Surg
|
1992
|
0.76
|
|
79
|
Dependence of plasmin-mediated degradation of platelet adhesive receptors on temperature and Ca2+.
|
Blood
|
1990
|
0.76
|
|
80
|
Mechanisms of vascular graft thrombosis: role of altered canine platelet sensitivity to thromboxane.
|
Thromb Res
|
1989
|
0.76
|
|
81
|
Extracellular FGF-1 inhibits cytoskeletal organization and promotes fibroblast motility.
|
Growth Factors
|
2000
|
0.76
|
|
82
|
On-site prothrombin time, activated partial thromboplastin time, and platelet count. A comparison between whole blood and laboratory assays with coagulation factor analysis in patients presenting for cardiac surgery.
|
Anesthesiology
|
1994
|
0.75
|
|
83
|
Effects of platelets and white blood cells and antiplatelet agent C7E3 (Reopro) on a new test of PAF procoagulant activity of whole blood.
|
Thromb Res
|
1997
|
0.75
|
|
84
|
Mechanism of inhibition by trinitrophenylation of the ristocetin cofactor activity of von Willebrand factor.
|
Biochim Biophys Acta
|
1984
|
0.75
|
|
85
|
Effects of antiplatelet drugs on dialysis-associated platelet deposition in polytetrafluoroethylene grafts.
|
Am J Kidney Dis
|
1997
|
0.75
|
|
86
|
Amino group modification inhibits ristocetin cofactor activity of human von Willebrand factor.
|
Biochem Biophys Res Commun
|
1982
|
0.75
|
|
87
|
The alpha 2 beta 1 integrin binds to the CB4 peptide of the alpha 2(I) collagen chain.
|
Biochem Mol Biol Int
|
1997
|
0.75
|
|
88
|
Preparation of soluble peptide libraries: application to studies of platelet adhesion sequences.
|
Biochem Int
|
1992
|
0.75
|
|
89
|
Ligand binding results in divalent cation displacement from the alpha 2 beta 1 integrin I domain: evidence from terbium luminescence spectroscopy.
|
Biochemistry
|
1998
|
0.75
|
|
90
|
Divalent cation-dependent structure in the platelet membrane glycoprotein Ia-IIa (VLA-2) complex.
|
Biochem Biophys Res Commun
|
1990
|
0.75
|
|
91
|
Alpha2beta1 integrin recognition of the carboxyl-terminal propeptide of type I procollagen: integrin recognition and feed-back regulation of matrix biosynthesis are mediated by distinct sequences.
|
Matrix Biol
|
1998
|
0.75
|
|
92
|
Duplicate coagulation assays warranted.
|
Am J Clin Pathol
|
1985
|
0.75
|
|
93
|
Multiple episodes of thrombosis with biventricular support devices with inadequate anticoagulation and evidence of accelerated intravascular coagulation.
|
J Thorac Cardiovasc Surg
|
1997
|
0.75
|
|
94
|
Assessment of interference by heparin cofactor II in the DuPont aca antithrombin-III assay.
|
Am J Clin Pathol
|
1988
|
0.75
|
|
95
|
Platelet interactions with fibronectin: divalent cation-independent platelet adhesion to the gelatin-binding domain of fibronectin.
|
Blood
|
1993
|
0.75
|
|
96
|
Effect of heparin on whole blood activated partial thromboplastin time using a portable, whole blood coagulation monitor.
|
Crit Care Med
|
1995
|
0.75
|
|
97
|
The nature of interactions between tissue-type plasminogen activator and platelets.
|
Thromb Res
|
1990
|
0.75
|
|
98
|
Platelets: platelet immunobiology.
|
Science
|
1989
|
0.75
|
|
99
|
Effect of aprotinin on activated clotting time, whole blood and plasma heparin measurements.
|
Ann Thorac Surg
|
1995
|
0.75
|
|
100
|
Platelet interactions with the vessel wall and prosthetic grafts.
|
Ann Vasc Surg
|
1993
|
0.75
|