PubRank

M Gassmann

Author PubWeight™ 106.24‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev 1998 12.48
2 Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth. Cancer Res 2000 6.14
3 Oxygen(es) and the hypoxia-inducible factor-1. Biol Chem 1997 2.81
4 HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia. FASEB J 2001 2.73
5 Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor. Mol Cell Biol 1996 2.72
6 Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta(3) J Clin Invest 2000 2.57
7 Induction of HIF-1alpha in response to hypoxia is instantaneous. FASEB J 2001 2.51
8 Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. J Biol Chem 1991 2.08
9 Embryoid bodies: an in vitro model of mouse embryogenesis. Exp Physiol 2000 2.02
10 Erythropoietin gene expression in human, monkey and murine brain. Eur J Neurosci 1996 1.91
11 Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases. Nature 1997 1.90
12 Localization of specific erythropoietin binding sites in defined areas of the mouse brain. Proc Natl Acad Sci U S A 1995 1.77
13 Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1. J Biol Chem 1997 1.67
14 Nitric oxide prevents cardiovascular disease and determines survival in polyglobulic mice overexpressing erythropoietin. Proc Natl Acad Sci U S A 2000 1.47
15 The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site. Nucleic Acids Res 1995 1.43
16 Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis. Mol Endocrinol 2000 1.41
17 Defects in pathfinding by cranial neural crest cells in mice lacking the neuregulin receptor ErbB4. Nat Cell Biol 2000 1.34
18 Regulation of the p59fyn protein tyrosine kinase by the CD45 phosphotyrosine phosphatase. Eur J Immunol 1992 1.32
19 Induction and nuclear translocation of hypoxia-inducible factor-1 (HIF-1): heterodimerization with ARNT is not necessary for nuclear accumulation of HIF-1alpha. J Cell Sci 1999 1.31
20 Hypoxia, a novel inducer of acute phase gene expression in a human hepatoma cell line. J Biol Chem 1995 1.29
21 Tyrosine phosphorylation of CD45 phosphotyrosine phosphatase by p50csk kinase creates a binding site for p56lck tyrosine kinase and activates the phosphatase. Mol Cell Biol 1994 1.26
22 Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-1 alpha. Biochem Biophys Res Commun 1996 1.23
23 Increased cerebral infarct volumes in polyglobulic mice overexpressing erythropoietin. J Cereb Blood Flow Metab 2001 1.22
24 Detection of erythropoietin in human liquor: intrinsic erythropoietin production in the brain. Kidney Int 1997 1.22
25 Calf thymus DNA polymerase delta: purification, biochemical and functional properties of the enzyme after its separation from DNA polymerase alpha, a DNA dependent ATPase and proliferating cell nuclear antigen. Nucleic Acids Res 1988 1.20
26 Hypoxic induction of gene expression in chronic granulomatous disease-derived B-cell lines: oxygen sensing is independent of the cytochrome b558-containing nicotinamide adenine dinucleotide phosphate oxidase. Blood 1996 1.19
27 Chronic inborn erythrocytosis leads to cardiac dysfunction and premature death in mice overexpressing erythropoietin. Blood 2001 1.19
28 Hypoxia-inducible factor-1 alpha is regulated at the post-mRNA level. Kidney Int 1997 1.15
29 Oxygen-regulated erythropoietin gene expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site. Eur J Biochem 1998 1.14
30 General applicability of chicken egg yolk antibodies: the performance of IgY immunoglobulins raised against the hypoxia-inducible factor 1alpha. FASEB J 1999 1.12
31 Neuroprotection by hypoxic preconditioning: HIF-1 and erythropoietin protect from retinal degeneration. Semin Cell Dev Biol 2005 1.12
32 Generation and application of chicken egg-yolk antibodies. Comp Biochem Physiol A Mol Integr Physiol 2002 1.11
33 Na-K-ATPase in rat cerebellar granule cells is redox sensitive. Am J Physiol Regul Integr Comp Physiol 2005 1.05
34 Hypoxia affects expression of circadian genes PER1 and CLOCK in mouse brain. FASEB J 2001 1.05
35 Mouse hypoxia-inducible factor-1alpha is encoded by two different mRNA isoforms: expression from a tissue-specific and a housekeeping-type promoter. Blood 1998 1.04
36 Calf thymus DNA polymerase delta independent of proliferating cell nuclear antigen (PCNA). Nucleic Acids Res 1989 1.03
37 The mouse gene for hypoxia-inducible factor-1alpha--genomic organization, expression and characterization of an alternative first exon and 5' flanking sequence. Eur J Biochem 1997 1.02
38 Efficient translation of mouse hypoxia-inducible factor-1alpha under normoxic and hypoxic conditions. Biochim Biophys Acta 2000 1.01
39 Maintaining blood-brain barrier integrity: pericytes perform better than astrocytes during prolonged oxygen deprivation. J Cell Physiol 2009 1.01
40 Attenuation of HIF-1 DNA-binding activity limits hypoxia-inducible endothelin-1 expression. Pflugers Arch 2001 1.00
41 Characterization of a hypoxia-inducible factor (HIF-1alpha ) from rainbow trout. Accumulation of protein occurs at normal venous oxygen tension. J Biol Chem 2001 0.99
42 Epolones induce erythropoietin expression via hypoxia-inducible factor-1 alpha activation. Blood 2000 0.98
43 Erythropoietin modulates intracellular calcium in a human neuroblastoma cell line. J Physiol 1999 0.98
44 Constitutive Notch2 signaling in neural stem cells promotes tumorigenic features and astroglial lineage entry. Cell Death Dis 2012 0.97
45 Hypoxia tolerance in animals: biology and application. Physiol Biochem Zool 2010 0.95
46 Tissue-specific expression of a FMR1/beta-galactosidase fusion gene in transgenic mice. Hum Mol Genet 1995 0.95
47 Oxygen tension modulates beta-globin switching in embryoid bodies. FASEB J 1999 0.95
48 Mammalian PASKIN, a PAS-serine/threonine kinase related to bacterial oxygen sensors. Biochem Biophys Res Commun 2001 0.94
49 Up-regulation of hypoxia-inducible factor-1alpha is not sufficient for hypoxic/anoxic p53 induction. Cancer Res 1998 0.93
50 Dissecting hypoxia-dependent and hypoxia-independent steps in the HIF-1alpha activation cascade: implications for HIF-1alpha gene therapy. FASEB J 2001 0.93
51 Oxygen sensing, HIF-1alpha stabilization and potential therapeutic strategies. Pflugers Arch 2001 0.92
52 Chronic excessive erythrocytosis induces endothelial activation and damage in mouse brain. Am J Physiol Regul Integr Comp Physiol 2005 0.90
53 Oxygen-regulated expression of TGF-beta 3, a growth factor involved in trophoblast differentiation. Placenta 2003 0.90
54 Expression of the Tyro4/Mek4/Cek4 gene specifically marks a subset of embryonic motor neurons and their muscle targets. Mol Cell Neurosci 1996 0.89
55 The hypoxia-inducible factor-1 DNA recognition site is cAMP-responsive. Kidney Int 1997 0.88
56 Hypoxia-regulated gene expression in fetal wound regeneration and adult wound repair. Pediatr Surg Int 2000 0.88
57 Determinants of time trial performance and maximal incremental exercise in highly trained endurance athletes. J Appl Physiol (1985) 2011 0.87
58 Expression of ErbB3, ErbB4, and neuregulin-1 mRNA during tooth development. Dev Dyn 2002 0.86
59 Chondroitin sulphate-binding molecules may pattern central projections of sensory axons within the cranial mesenchyme of the developing mouse. Dev Biol 1999 0.86
60 A polyoma-based episomal vector efficiently expresses exogenous genes in mouse embryonic stem cells. Nucleic Acids Res 1996 0.85
61 Timing the arrival at 2340 m altitude for aerobic performance. Scand J Med Sci Sports 2007 0.85
62 Genetically modified mouse models in studies on cutaneous wound healing. Exp Physiol 2000 0.84
63 Erythropoietin expression in primary rat Sertoli and peritubular myoid cells. Blood 2001 0.83
64 Hypoxic responses of Na+/K+ ATPase in trout hepatocytes. J Exp Biol 2005 0.82
65 Pivotal role of reduced glutathione in oxygen-induced regulation of the Na(+)/K(+) pump in mouse erythrocyte membranes. J Membr Biol 2003 0.81
66 Formation of Neu/ErbB2-induced mammary tumors is unaffected by loss of ErbB4. Oncogene 2006 0.81
67 CD45 phosphotyrosine phosphatase and p56lck protein tyrosine kinase: a functional complex crucial in T cell signal transduction. Int Immunol 1992 0.81
68 Optimal erythropoietin expression in human hepatoma cell lines requires activation of multiple signalling pathways. Int J Mol Med 1998 0.80
69 First aid kit for hypoxic survival: sensors and strategies. Physiol Biochem Zool 2010 0.79
70 Calcium-dependent calmodulin-binding proteins associated with mammalian DNA polymerase alpha. Biochim Biophys Acta 1988 0.79
71 Mammalian DNA polymerase alpha: a replication-competent holoenzyme form from calf thymus. Philos Trans R Soc Lond B Biol Sci 1987 0.78
72 Constitutive excessive erythrocytosis causes inflammation and increased vascular permeability in aged mouse brain. Brain Res 2013 0.78
73 Mammalian gene expression in hypoxic conditions. Zoology (Jena) 2001 0.77
74 Adjuvant therapy of pancreatic cancer using monoclonal antibodies and immune response modifiers. Int J Pancreatol 1997 0.77
75 Effects of hypobaric hypoxia on vascular endothelial growth factor and the acute phase response in subjects who are susceptible to high-altitude pulmonary oedema. Eur J Appl Physiol 2000 0.77
76 Little difference. Nature 1996 0.77
77 Pharmacokinetics of ramipril in hypertensive patients with renal insufficiency. Eur J Clin Pharmacol 1989 0.76
78 Ultrastructural cryoimmunocytochemistry is a convenient tool for the study of DNA replication in cultured cells. J Electron Microsc Tech 1991 0.75
79 Fetuses from preeclamptic mothers show reduced hepatic erythropoiesis. Pediatr Res 1998 0.75
80 Steady-state kinetics of ramipril in renal failure. J Cardiovasc Pharmacol 1989 0.75
81 [Contribution to the study of Trematodes in Amphibians from the Cameroon (author's transl)]. Ann Parasitol Hum Comp 1976 0.75
82 Therapeutic efficacy and tolerance of ramipril in hypertensive patients with renal failure. J Cardiovasc Pharmacol 1989 0.75
83 [Various problems posed by the introduction of linguistics in the analysis of articulation and speech disorders]. Phonetica 1977 0.75
84 Mitochondria contaminate databases. Trends Genet 1995 0.75
85 Endogenous α-calcitonin-gene-related peptide promotes exercise-induced, physiological heart hypertrophy in mice. Acta Physiol (Oxf) 2014 0.75
86 [Gene technology and veterinary medicine. III. Transgenic animals: facts and perspectives]. Schweiz Arch Tierheilkd 1987 0.75