Stem cells in the central nervous system.

Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci U S A (2000) 10.88

Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas. Proc Natl Acad Sci U S A (2000) 5.49

Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat. Proc Natl Acad Sci U S A (2001) 4.36

Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats--similarities to astrocyte grafts. Proc Natl Acad Sci U S A (1998) 4.13

Radial glia give rise to adult neural stem cells in the subventricular zone. Proc Natl Acad Sci U S A (2004) 3.91

A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination. Nat Struct Mol Biol (2009) 2.96

Neurotransplantation of magnetically labeled oligodendrocyte progenitors: magnetic resonance tracking of cell migration and myelination. Proc Natl Acad Sci U S A (1999) 2.42

Differential distribution of stem cells in the auditory and vestibular organs of the inner ear. J Assoc Res Otolaryngol (2006) 2.41

Transplanted bone marrow generates new neurons in human brains. Proc Natl Acad Sci U S A (2003) 2.20

"Global" cell replacement is feasible via neural stem cell transplantation: evidence from the dysmyelinated shiverer mouse brain. Proc Natl Acad Sci U S A (1999) 2.16

Evidence for neurogenesis in the adult mammalian substantia nigra. Proc Natl Acad Sci U S A (2003) 2.12

Neural stem cell heterogeneity demonstrated by molecular phenotyping of clonal neurospheres. Proc Natl Acad Sci U S A (2002) 2.04

BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis. Proc Natl Acad Sci U S A (2001) 2.01

GDNF secreting human neural progenitor cells protect dying motor neurons, but not their projection to muscle, in a rat model of familial ALS. PLoS One (2007) 1.99

Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal. Nat Cell Biol (2009) 1.94

Interaction between astrocytes and adult subventricular zone precursors stimulates neurogenesis. Proc Natl Acad Sci U S A (1999) 1.90

Heterogeneity of neural progenitor cells revealed by enhancers in the nestin gene. Dev Biol (1999) 1.81

Adult hippocampal neurogenesis: regulation, functional implications, and contribution to disease pathology. Neurosci Biobehav Rev (2008) 1.77

Neural stem cell self-renewal. Crit Rev Oncol Hematol (2007) 1.76

Glioma tropic neural stem cells consist of astrocytic precursors and their migratory capacity is mediated by CXCR4. Neoplasia (2004) 1.56

Tumor necrosis factor alpha triggers proliferation of adult neural stem cells via IKK/NF-kappaB signaling. BMC Neurosci (2006) 1.52

Adult neurogenesis and cellular brain repair with neural progenitors, precursors and stem cells. Philos Trans R Soc Lond B Biol Sci (2006) 1.44

Human neural stem cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model. PLoS One (2007) 1.41

Purinergic signaling regulates neural progenitor cell expansion and neurogenesis. Dev Biol (2006) 1.41

Protection of visual functions by human neural progenitors in a rat model of retinal disease. PLoS One (2007) 1.38

Differential modulation of BMP signaling promotes the elaboration of cerebral cortical GABAergic neurons or oligodendrocytes from a common sonic hedgehog-responsive ventral forebrain progenitor species. Proc Natl Acad Sci U S A (2002) 1.37

Expression of oligodendrocyte progenitor cell antigens by gliomas: implications for the histogenesis of brain tumors. Proc Natl Acad Sci U S A (1999) 1.36

Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor. Proc Natl Acad Sci U S A (2004) 1.36

Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation. Proc Natl Acad Sci U S A (2002) 1.36

Mild hypoxia enhances proliferation and multipotency of human neural stem cells. PLoS One (2010) 1.35

Generation of neural progenitor cells by chemical cocktails and hypoxia. Cell Res (2014) 1.30

Olig2+ neuroepithelial motoneuron progenitors are not multipotent stem cells in vivo. Proc Natl Acad Sci U S A (2006) 1.30

"...those left behind." Biology and oncology of invasive glioma cells. Neoplasia (1999) 1.24

Neural progenitor cells from postmortem adult human retina. Br J Ophthalmol (2005) 1.22

Region-specific differentiation of neural tube-derived neuronal restricted progenitor cells after heterotopic transplantation. Proc Natl Acad Sci U S A (2000) 1.21

The FGF-2/FGFRs neurotrophic system promotes neurogenesis in the adult brain. J Neural Transm (Vienna) (2009) 1.20

Intrinsic regenerative potential of murine cochlear supporting cells. Sci Rep (2011) 1.20

Spinal cord neuronal precursors generate multiple neuronal phenotypes in culture. J Neurosci (1998) 1.17

Altered differentiation of neural stem cells in fragile X syndrome. Proc Natl Acad Sci U S A (2005) 1.16

Regulation of hematopoietic stem cell aging in vivo by a distinct genetic element. Proc Natl Acad Sci U S A (2005) 1.15

Functional roles of gangliosides in neurodevelopment: an overview of recent advances. Neurochem Res (2012) 1.14

Human dental pulp stem cells demonstrate better neural and epithelial stem cell properties than bone marrow-derived mesenchymal stem cells. Histochem Cell Biol (2011) 1.14

Neuron-like differentiation of bone marrow-derived mesenchymal stem cells. Yonsei Med J (2011) 1.13

Murine neural stem/progenitor cells protect neurons against ischemia by HIF-1alpha-regulated VEGF signaling. PLoS One (2010) 1.12

Neural stem cells: involvement in adult neurogenesis and CNS repair. Philos Trans R Soc Lond B Biol Sci (2008) 1.12

Expression of the bHLH transcription factor Tcf12 (ME1) gene is linked to the expansion of precursor cell populations during neurogenesis. Brain Res Gene Expr Patterns (2002) 1.10

The new stem cell biology: something for everyone. Mol Pathol (2003) 1.10

Mitotic and neurogenic effects of dehydroepiandrosterone (DHEA) on human neural stem cell cultures derived from the fetal cortex. Proc Natl Acad Sci U S A (2004) 1.10

MRI evaluation of axonal reorganization after bone marrow stromal cell treatment of traumatic brain injury. NMR Biomed (2011) 1.08

Neural stem cells as engraftable packaging lines can mediate gene delivery to microglia: evidence from studying retroviral env-related neurodegeneration. J Virol (1999) 1.07

Thyroid hormone activates oligodendrocyte precursors and increases a myelin-forming protein and NGF content in the spinal cord during experimental allergic encephalomyelitis. Proc Natl Acad Sci U S A (2002) 1.06

Genetic and transcriptional control of bone formation. Oral Maxillofac Surg Clin North Am (2010) 1.05

REST-VP16 activates multiple neuronal differentiation genes in human NT2 cells. Nucleic Acids Res (2000) 1.05

Robust postmortem survival of murine vestibular and cochlear stem cells. J Assoc Res Otolaryngol (2007) 1.04

Chemokine-mobilized adult stem cells; defining a better hematopoietic graft. Leukemia (2007) 1.04

Expression of nestin by neural cells in the adult rat and human brain. PLoS One (2011) 1.03

Characterization of GD3 ganglioside as a novel biomarker of mouse neural stem cells. Glycobiology (2009) 1.03

Glycogen synthase kinase-3 regulates endoplasmic reticulum (ER) stress-induced CHOP expression in neuronal cells. Exp Cell Res (2011) 1.02

Stacking the DEK: from chromatin topology to cancer stem cells. Cell Cycle (2012) 1.01

Production of neurospheres from CNS tissue. Methods Mol Biol (2008) 1.01

Prion infection of mouse neurospheres. Proc Natl Acad Sci U S A (2006) 1.01

Human neural stem cells genetically modified to overexpress Akt1 provide neuroprotection and functional improvement in mouse stroke model. PLoS One (2009) 1.00

Interferon-gamma produced by microglia and the neuropeptide PACAP have opposite effects on the viability of neural progenitor cells. PLoS One (2010) 0.99

Lewis X-carrying N-glycans regulate the proliferation of mouse embryonic neural stem cells via the Notch signaling pathway. J Biol Chem (2012) 0.98

Neuroregeneration in neurodegenerative disorders. BMC Neurol (2011) 0.98

Genetic methods to identify and manipulate newly born neurons in the adult brain. Front Neurosci (2011) 0.97

Expression of GD2 and GD3 gangliosides in human embryonic neural stem cells. ASN Neuro (2011) 0.97

Stem cell-derived motor neurons: applications and challenges in amyotrophic lateral sclerosis. Curr Stem Cell Res Ther (2009) 0.95

Regrowing the adult brain: NF-κB controls functional circuit formation and tissue homeostasis in the dentate gyrus. PLoS One (2012) 0.94

Direct stimulation of adult neural stem/progenitor cells in vitro and neurogenesis in vivo by salvianolic acid B. PLoS One (2012) 0.94

Subventricular zone neural progenitors from rapid brain autopsies of elderly subjects with and without neurodegenerative disease. J Comp Neurol (2009) 0.94

Nestin-positive mesenchymal stem cells favour the astroglial lineage in neural progenitors and stem cells by releasing active BMP4. BMC Neurosci (2004) 0.94

Exercise increases neural stem cell proliferation surrounding the area of damage following rat traumatic brain injury. J Neural Transm (Vienna) (2010) 0.94

Intracerebral transplantation of neural stem cells combined with trehalose ingestion alleviates pathology in a mouse model of Huntington's disease. J Neurosci Res (2009) 0.92

The inner ear and the neurologist. J Neurol Neurosurg Psychiatry (2007) 0.92

Direct reprogramming of melanocytes to neural crest stem-like cells by one defined factor. Stem Cells (2011) 0.91

Selective expression of presenilin 1 in neural progenitor cells rescues the cerebral hemorrhages and cortical lamination defects in presenilin 1-null mutant mice. Development (2005) 0.91

O-linked beta-N-acetylglucosaminylation in mouse embryonic neural precursor cells. J Neurosci Res (2009) 0.91

Cerebrospinal fluid promotes survival and astroglial differentiation of adult human neural progenitor cells but inhibits proliferation and neuronal differentiation. BMC Neurosci (2010) 0.91

Trans-differentiation of neural stem cells: a therapeutic mechanism against the radiation induced brain damage. PLoS One (2012) 0.90

Immortalization of human neural stem cells with the c-myc mutant T58A. PLoS One (2008) 0.89

Stem cells as tools in regenerative therapy for retinal degeneration. Arch Ophthalmol (2009) 0.89

Cell therapies for traumatic brain injury. Neurosurg Focus (2008) 0.89

HNK-1 epitope-carrying tenascin-C spliced variant regulates the proliferation of mouse embryonic neural stem cells. J Biol Chem (2010) 0.89

Involvement of beta1-integrin up-regulation in basic fibroblast growth factor- and epidermal growth factor-induced proliferation of mouse neuroepithelial cells. J Biol Chem (2010) 0.89

Reactivation of latent cytomegalovirus infection in mouse brain cells detected after transfer to brain slice cultures. J Virol (2002) 0.89

Chinese herbs and their active ingredients for activating xue (blood) promote the proliferation and differentiation of neural stem cells and mesenchymal stem cells. Chin Med (2014) 0.88

Growth factors improve neurogenesis and outcome after focal cerebral ischemia. J Neural Transm (Vienna) (2009) 0.87

The p75 neurotrophin receptor is expressed by adult mouse dentate progenitor cells and regulates neuronal and non-neuronal cell genesis. BMC Neurosci (2010) 0.87

Clinical translation of human neural stem cells. Stem Cell Res Ther (2013) 0.87

Pax6 mediates ß-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells. Stem Cells (2014) 0.87

Systemic administration of mesenchymal stem cells increases neuron survival after global cerebral ischemia in vivo (2VO). Neural Plast (2010) 0.87

Etanercept attenuates traumatic brain injury in rats by reducing brain TNF- α contents and by stimulating newly formed neurogenesis. Mediators Inflamm (2013) 0.87

Future approaches for inner ear protection and repair. J Commun Disord (2010) 0.87

Transplanted bone marrow mesenchymal stem cells improve memory in rat models of Alzheimer's disease. Stem Cells Int (2012) 0.86

Use of autologous mesenchymal stem cells derived from bone marrow for the treatment of naturally injured spinal cord in dogs. Stem Cells Int (2014) 0.86

Interactions between the NO-citrulline cycle and brain-derived neurotrophic factor in differentiation of neural stem cells. J Biol Chem (2012) 0.86

Human umbilical cord blood-derived mesenchymal stem cell therapy promotes functional recovery of contused rat spinal cord through enhancement of endogenous cell proliferation and oligogenesis. J Biomed Biotechnol (2012) 0.85

The survival of neural precursor cell grafts is influenced by in vitro expansion. J Anat (2005) 0.85

Cell-based therapy for stroke. J Neural Transm (Vienna) (2010) 0.85