Published in Science on November 18, 1977
Perspectives and opportunities for nanomedicine in the management of atherosclerosis. Nat Rev Drug Discov (2011) 1.78
pH (low) insertion peptide (pHLIP) targets ischemic myocardium. Proc Natl Acad Sci U S A (2012) 0.96
ATP-loaded liposomes effectively protect mechanical functions of the myocardium from global ischemia in an isolated rat heart model. J Control Release (2005) 0.84
Association of liposomes with the isolated perfused rabbit heart. Basic Res Cardiol (1983) 0.77
Liposomes in diagnosis and treatment of cardiovascular disorders. Methodist Debakey Cardiovasc J (2012) 0.76
A noninvasive scintiphotographic method for detecting regional ventricular dysfunction in man. N Engl J Med (1971) 2.05
Noninvasive regional myocardial perfusion with radioactive potassium. Study of patients at rest, with exercise and during angina pectoris. N Engl J Med (1973) 1.95
Prognostic implications of mental stress-induced silent left ventricular dysfunction in patients with stable angina pectoris. Am J Cardiol (1995) 1.88
Contributions of nuclear cardiology to diagnosis and prognosis of patients with coronary artery disease. Circulation (2000) 1.64
Radionuclide assessment of peripheral intravascular capacity: a technique to measure intravascular volume changes in the capacitance circulation in man. Circulation (1981) 1.45
Functional left ventricular aneurysm formation after acute anterior transmural myocardial infarction. Incidence, natural history, and prognostic implications. N Engl J Med (1984) 1.44
Coronary artery bypass grafting in severe left ventricular dysfunction: excellent survival with improved ejection fraction and functional state. J Am Coll Cardiol (1993) 1.43
Intact systolic left ventricular function in clinical congestive heart failure. Am J Cardiol (1985) 1.43
Technetium-99m-nitroimidazole (BMS181321): a positive imaging agent for detecting myocardial ischemia. J Nucl Med (1995) 1.43
The technetium-99m-DTPA renal uptake-plasma volume product: a quantitative estimation of glomerular filtration rate. J Nucl Med (1992) 1.40
Preoperative dipyridamole thallium imaging and ambulatory electrocardiographic monitoring as a predictor of perioperative cardiac events and long-term outcome. Anesthesiology (1995) 1.40
Cerebral cortical hyperactivation in response to mental stress in patients with coronary artery disease. Proc Natl Acad Sci U S A (1998) 1.38
A scintiphotographic method for measuring left ventricular ejection fraction in man without cardiac catheterization. Am J Cardiol (1971) 1.37
Assessment of cardiac performance with quantitative radionuclide angiocardiography: right ventricular ejection fraction with reference to findings in chronic obstructive pulmonary disease. Am J Cardiol (1978) 1.37
Usefulness of verapamil for congestive heart failure associated with abnormal left ventricular diastolic filling and normal left ventricular systolic performance. Am J Cardiol (1990) 1.34
Role of behavioral and psychological factors in mental stress-induced silent left ventricular dysfunction in coronary artery disease. J Am Coll Cardiol (1993) 1.33
Range of normal values for left and right ventricular ejection fraction at rest and during exercise assessed by radionuclide angiocardiography. Eur Heart J (1985) 1.33
Physiologic correlates of right ventricular ejection fraction in chronic obstructive pulmonary disease: a combined radionuclide and hemodynamic study. Am J Cardiol (1982) 1.30
Multiple gated cardiac blood pool imaging for left ventricular ejection fraction: validation of the technique and assessment of variability. Am J Cardiol (1979) 1.26
Serial assessment of doxorubicin cardiotoxicity with quantitative radionuclide angiocardiography. N Engl J Med (1979) 1.25
Myocardial blood-flow response during mental stress in patients with coronary artery disease. Lancet (2000) 1.25
Assessment of cardiac performance with quantitative radionuclide angiocardiography: sequential left ventricular ejection fraction, normalized left ventricular ejection rate, and regional wall motion. Circulation (1977) 1.20
Scintigraphic determination of small intestinal transit time: comparison with the hydrogen breath technique. Gastroenterology (1984) 1.19
Augmentation of right ventricular performance in chronic obstructive pulmonary disease by terbutaline: a combined radionuclide and hemodynamic study. Am J Cardiol (1982) 1.16
Beat-to-beat left ventricular performance assessed from the equilibrium cardiac blood pool using a computerized nuclear probe. Circulation (1981) 1.14
An isotopic method for measurement of muscle protein synthesis and degradation in vivo. Biochem J (1987) 1.11
Sequential radionuclide assessment of left and right ventricular performance after acute transmural myocardial infarction. Ann Intern Med (1978) 1.08
Serial quantitative planar technetium-99m isonitrile imaging in acute myocardial infarction: efficacy for noninvasive assessment of thrombolytic therapy. J Am Coll Cardiol (1989) 1.08
Rest and exercise potassium-43 myocardial perfusion imaging for the noninvasive evaluation of aortocoronary bypass surgery. Circulation (1974) 1.08
Infundibular pulmonic stenosis with intact ventricular septum in the adult. Johns Hopkins Med J (1973) 1.07
Response of right ventricular ejection fraction to upright bicycle exercise in coronary artery disease. Circulation (1979) 1.07
Myocardial imaging with thallium-201: a multicenter study in patients with angina pectoris or acute myocardial infarction. Am J Cardiol (1978) 1.06
Left ventricular systolic performance during upright bicycle exercise in patients with essential hypertension. Am J Med (1983) 1.06
Variability in sequential measures of left ventricular performance assessed with radionuclide angiocardiography. Am J Cardiol (1978) 1.04
Percutaneous transluminal coronary angioplasty of the "culprit lesion" for management of unstable angina pectoris in patients with multivessel coronary artery disease. Am J Cardiol (1986) 1.03
First-pass radionuclide assessment of right and left ventricular performance in patients with cardiac and pulmonary disease. Semin Nucl Med (1979) 1.02
Global and regional left ventricular response to bicycle exercise in coronary artery disease. Assessment by quantitative radionuclide angiocardiography. Am J Med (1979) 1.02
Biokinetics of technetium-99m-tetrofosmin: myocardial perfusion imaging agent: implications for a one-day imaging protocol. J Nucl Med (1993) 1.02
Multigated equilibrium radionuclide angiocardiography: improved detection of left ventricular wall motion abnormalities and aneurysms by the addition of the left lateral view. Radiology (1981) 1.01
Technetium-99m-tetrofosmin to assess myocardial blood flow: experimental validation in an intact canine model of ischemia. J Nucl Med (1994) 1.00
Nuclear cardiology (first of two parts). N Engl J Med (1981) 0.99
Value of scintigraphy in chronic peritoneal dialysis patients. Kidney Int (1999) 0.97
Myocardial imaging with radioactive potassium and its analogs. Prog Cardiovasc Dis (1977) 0.97
The mechanism of liposome accumulation in infarction. Biochim Biophys Acta (1984) 0.95
Renin-like activity in ovarian follicular fluid. Fertil Steril (1985) 0.94
Distortion of the terminal portion of the QRS on the admission electrocardiogram in acute myocardial infarction and correlation with infarct size and long-term prognosis (Thrombolysis in Myocardial Infarction 4 Trial). Am J Cardiol (1996) 0.94
Radionuclide assessment of right and left ventricular exercise reserve after total correction of tetralogy of Fallot. Am J Cardiol (1980) 0.94
Ordering patterns and clinical impact of cardiovascular nuclear medicine procedures. Circulation (1980) 0.94
Results of coronary artery bypass grafting by a single surgeon in patients with left ventricular ejection fractions < or = 30%. Am J Cardiol (1997) 0.93
Cardiac prostaglandin release during myocardial ischemia induced by atrial pacing in patients with coronary artery disease. Am J Cardiol (1977) 0.93
Imaging experimental myocardial infarction with indium-111-labeled autologous leukocytes: effects of infarct age and residual regional myocardial blood flow. Circulation (1979) 0.92
Noninvasive myocardial imaging with potassium-43 and rubidium-81 in patients with left bundle branch block. Am J Cardiol (1976) 0.91
Transient left ventricular dysfunction during provocative mental stress in patients with coronary artery disease. Am Heart J (1989) 0.91
Comparison of exercise radionuclide angiocardiography and thallium-201 myocardial perfusion imaging in coronary artery disease. Am J Cardiol (1980) 0.91
Imaging experimental infective endocarditis with indium-111-labeled blood cellular components. Circulation (1979) 0.91
Right and left ventricular exercise performance in chronic obstructive pulmonary disease: radionuclide assessment. Ann Intern Med (1980) 0.91
Effects of mental stress on left ventricular and peripheral vascular performance in patients with coronary artery disease. J Am Coll Cardiol (1998) 0.90
Regional myocardial dysfunction during coronary angioplasty: evaluation by two-dimensional echocardiography and 12 lead electrocardiography. J Am Coll Cardiol (1986) 0.90
Regional cardiac prostaglandin release during myocardial ischemia in anesthetized dogs. Circ Res (1976) 0.89
The ovarian renin-angiotensin system: renin-like activity and angiotensin II/III immunoreactivity in gonadotropin-stimulated and unstimulated human follicular fluid. Am J Obstet Gynecol (1987) 0.89
Pathophysiological correlates of thallium-201 myocardial uptake in experimental infarction. Cardiovasc Res (1977) 0.89
Imaging experimental coronary artery thrombosis with indium-111 platelets. Circulation (1979) 0.88
Right ventricular performance and central circulatory hemodynamics during upright exercise in patients with chronic obstructive pulmonary disease. Am Rev Respir Dis (1984) 0.88
Exercise left ventricular performance in patients with chest pain, ischemic-appearing exercise electrocardiograms, and angiographically normal coronary arteries. Ann Intern Med (1981) 0.88
Radionuclide stress myocardial perfusion imaging: the future gatekeeper for coronary angiography. J Nucl Cardiol (1998) 0.88
Nuclear cardiology (second of two parts). N Engl J Med (1981) 0.87
Long-term outcome in patients with congestive heart failure and intact systolic left ventricular performance. Am J Cardiol (1992) 0.87
Transient ST-segment elevation with postmyocardial infarction angina: prognostic significance. Am Heart J (1975) 0.87
Beat-to-beat left ventricular performance in atrial fibrillation: radionuclide assessment with the computerized nuclear probe. Am J Cardiol (1983) 0.87
Quantification of SPECT myocardial perfusion images: methodology and validation of the Yale-CQ method. J Nucl Cardiol (1999) 0.87
Myocsrdial uptake of technetium-99m stannous pyrophosphate following direct current transthoracic countershock. Circulation (1976) 0.86
Spontaneous changes in left ventricular function over the first 24 hours of acute myocardial infarction: implications for evaluating early therapeutic interventions. Circulation (1982) 0.86
Continuous monitoring of left ventricular performance with the computerized nuclear probe during laryngoscopy and intubation before coronary artery bypass surgery. Am J Cardiol (1982) 0.85
Imaging the inflammatory response to acute myocardial infarction in man using indium-111-labeled autologous platelets. Circulation (1981) 0.85
Peak filling rate normalized to mitral stroke volume: a new Doppler echocardiographic filling index validated by radionuclide angiographic techniques. J Am Coll Cardiol (1988) 0.85
Myocardial protein turnover in patients with coronary artery disease. Effect of branched chain amino acid infusion. J Clin Invest (1991) 0.85
Potassium-43 myocardial perfusion scanning for the noninvasive evaluation of patients with false-positive exercise tests. Circulation (1973) 0.85
Effects of aminophylline upon right and left ventricular performance in chronic obstructive pulmonary disease: noninvasive assessment by radionuclide angiocardiography. Am J Med (1978) 0.85
Volumetric responses of right and left ventricles during upright exercise in normal subjects. J Appl Physiol (1985) (1985) 0.85
Improvement in cardiac performance by oral long-acting theophylline in chronic obstructive pulmonary disease. Am Heart J (1982) 0.85
Regulation by insulin of myocardial glucose and fatty acid metabolism in the conscious dog. J Clin Invest (1984) 0.84
Assessment of cardiac performance with quantitative radionuclide angiocardiography. Effects of oral propranolol on global and regional left ventricular function in coronary artery disease. Circulation (1978) 0.84
Rubidium-81: a new myocardial scanning agent. Radiology (1974) 0.84
Relationship between reverse redistribution on planar thallium scintigraphy and regional myocardial viability: a correlative PET study. J Nucl Med (1995) 0.84
Regeneration of splenic autotransplants in suckling and adult rats. Arch Surg (1981) 0.83
Assessment of right ventricular function. Role of nuclear imaging techniques. Cardiol Clin (1992) 0.83
Relationship of scar and ischemia to the results of programmed electrophysiological stimulation in patients with coronary artery disease. J Nucl Cardiol (1997) 0.83
Regulation of myocardial amino acid balance in the conscious dog. J Clin Invest (1985) 0.83
Diagnosis of discitis by SPECT technetium-99m MDP scintigram. A case report. Clin Nucl Med (1987) 0.83
Regeneration of the mammalian liver. 3. Electrokinetics of replicating cells treated with anti-mitotic antibiotics. Proc Soc Exp Biol Med (1966) 0.82
Clinical correlates of coronary cineangiography in young males with myocardial infarction. Am Heart J (1976) 0.82
Effects of oral digoxin on ventricular ectopy and its relation to left ventricular function. Am J Cardiol (1983) 0.82
Evaluation of liposome-entrapped radioactive tracers as scanning agents. Part 1: Organ distribution of liposome (99mTc-DTPA) in mice. J Nucl Med (1976) 0.82
Use of radionuclides to evaluate myocardial structure and function. Adv Intern Med (1980) 0.82
Effect on outcome of the presence or absence of chest pain at initiation of recombinant tissue plasminogen activator therapy in acute myocardial infarction. The Thrombolysis in Myocardial Infarction Investigators. Am J Cardiol (1994) 0.82
Noninvasive evaluation of regional myocardial perfusion with potassium 43. Technique in patients with exercise-induced transient myocardial ischemia. Radiology (1973) 0.82
Limitations of dobutamine for enhancing flow heterogeneity in the presence of single coronary stenosis: implications for technetium-99m-sestamibi imaging. J Nucl Med (1998) 0.82
Dual radionuclide study of acute myocardial infarction: comparison of thallium-201 and technetium-99m stannous prophosphate imaging in man. Ann Intern Med (1978) 0.82
Right and left ventricular performance in ambulatory young adults with cystic fibrosis. Br Heart J (1980) 0.82