Published in Cell on April 18, 1997
Similarities and differences among 105 members of the Int family of site-specific recombinases. Nucleic Acids Res (1998) 3.71
The integrase family of tyrosine recombinases: evolution of a conserved active site domain. Nucleic Acids Res (1997) 2.65
Structure of the Holliday junction intermediate in Cre-loxP site-specific recombination. EMBO J (1998) 2.47
Identification of a cytolethal distending toxin gene locus and features of a virulence-associated region in Actinobacillus actinomycetemcomitans. Infect Immun (1999) 1.97
Crystal structure of the site-specific recombinase, XerD. EMBO J (1997) 1.86
X-ray structure of T4 endonuclease VII: a DNA junction resolvase with a novel fold and unusual domain-swapped dimer architecture. EMBO J (1999) 1.55
The structure of a replication initiator unites diverse aspects of nucleic acid metabolism. Proc Natl Acad Sci U S A (2002) 1.41
A poxvirus-like type IB topoisomerase family in bacteria. Proc Natl Acad Sci U S A (2002) 1.31
Arm-site binding by lambda -integrase: solution structure and functional characterization of its amino-terminal domain. Proc Natl Acad Sci U S A (2002) 1.23
The small DNA binding domain of lambda integrase is a context-sensitive modulator of recombinase functions. EMBO J (2001) 1.21
Viewing single lambda site-specific recombination events from start to finish. EMBO J (2006) 1.19
Integron integrases possess a unique additional domain necessary for activity. J Bacteriol (2001) 1.18
Evolution of variants of yeast site-specific recombinase Flp that utilize native genomic sequences as recombination target sites. Nucleic Acids Res (2006) 1.13
Assembly and activation of site-specific recombination complexes. Proc Natl Acad Sci U S A (2000) 1.08
Wild-type Flp recombinase cleaves DNA in trans. EMBO J (1999) 1.05
Mechanism of DNA transesterification by vaccinia topoisomerase: catalytic contributions of essential residues Arg-130, Gly-132, Tyr-136 and Lys-167. Nucleic Acids Res (1997) 1.05
Identification of the lambda integrase surface that interacts with Xis reveals a residue that is also critical for Int dimer formation. Proc Natl Acad Sci U S A (2003) 1.03
The amino terminus of bacteriophage lambda integrase is involved in protein-protein interactions during recombination. J Bacteriol (2000) 1.02
Vaccinia topoisomerase and Cre recombinase catalyze direct ligation of activated DNA substrates containing a 3'-para-nitrophenyl phosphate ester. Nucleic Acids Res (2000) 0.94
Conservation of structure and function among tyrosine recombinases: homology-based modeling of the lambda integrase core-binding domain. Nucleic Acids Res (2003) 0.94
Active site electrostatics protect genome integrity by blocking abortive hydrolysis during DNA recombination. EMBO J (2009) 0.90
Structure-function analysis of IntDOT. J Bacteriol (2009) 0.87
Protein and DNA requirements of the bacteriophage HP1 recombination system: a model for intasome formation. Nucleic Acids Res (2001) 0.86
Coming or going it's another pretty picture for the lambda-Int family album. Proc Natl Acad Sci U S A (1999) 0.82
Interaction of the FimB integrase with the fimS invertible DNA element in Escherichia coli in vivo and in vitro. J Bacteriol (2000) 0.82
The structure of an archaeal viral integrase reveals an evolutionarily conserved catalytic core yet supports a mechanism of DNA cleavage in trans. J Virol (2012) 0.81
Protein folding coupled to DNA binding in the catalytic domain of bacteriophage lambda integrase detected by mass spectrometry. Protein Sci (2003) 0.81
Two tricks in one bundle: helix-turn-helix gains enzymatic activity. Nucleic Acids Res (2000) 0.81
DNA recognition, strand selectivity, and cleavage mode during integrase family site-specific recombination. J Biol Chem (2000) 0.81
Recombinogenic flap ligation pathway for intrinsic repair of topoisomerase IB-induced double-strand breaks. Mol Cell Biol (2000) 0.81
Stoichiometric incorporation of base substitutions at specific sites in supercoiled DNA and supercoiled recombination intermediates. Nucleic Acids Res (2010) 0.80
The carboxy-terminal αN helix of the archaeal XerA tyrosine recombinase is a molecular switch to control site-specific recombination. PLoS One (2013) 0.80
Mutational analysis and homology-based modeling of the IntDOT core-binding domain. J Bacteriol (2009) 0.77
A functional type I topoisomerase from Pseudomonas aeruginosa. BMC Mol Biol (2009) 0.75
Sequence and Structure Analysis of Distantly-Related Viruses Reveals Extensive Gene Transfer between Viruses and Hosts and among Viruses. Viruses (2015) 0.75
Xer Site Specific Recombination: Double and Single Recombinase Systems. Front Microbiol (2017) 0.75
Identification and arrangement of the DNA sequence recognized in specific transformation of Neisseria gonorrhoeae. Proc Natl Acad Sci U S A (1988) 4.04
Amyloid fibril formation by A beta 16-22, a seven-residue fragment of the Alzheimer's beta-amyloid peptide, and structural characterization by solid state NMR. Biochemistry (2000) 3.65
Specificity in deoxyribonucleic acid uptake by transformable Haemophilus influenzae. J Bacteriol (1974) 3.12
Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium. Proc Natl Acad Sci U S A (1998) 2.98
The integrase family of tyrosine recombinases: evolution of a conserved active site domain. Nucleic Acids Res (1997) 2.65
Constitution of the cell envelope of Haemophilus influenzae in relation to competence for genetic transformation. J Bacteriol (1975) 2.42
Solid state NMR reveals a pH-dependent antiparallel beta-sheet registry in fibrils formed by a beta-amyloid peptide. J Mol Biol (2004) 2.33
Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation. Cell (2001) 2.31
Catalytic domain of human immunodeficiency virus type 1 integrase: identification of a soluble mutant by systematic replacement of hydrophobic residues. Proc Natl Acad Sci U S A (1995) 2.09
Crystal structure of the thiamin diphosphate-dependent enzyme pyruvate decarboxylase from the yeast Saccharomyces cerevisiae at 2.3 A resolution. J Mol Biol (1996) 1.74
The structural basis of ordered substrate binding by serotonin N-acetyltransferase: enzyme complex at 1.8 A resolution with a bisubstrate analog. Cell (1999) 1.62
Nucleotide sequences and properties of the sites involved in lysogenic insertion of the bacteriophage HP1c1 genome into the Haemophilus influenzae chromosome. J Bacteriol (1987) 1.60
Unexpected structural diversity in DNA recombination: the restriction endonuclease connection. Mol Cell (2000) 1.44
Synthesis of envelope polypeptides by Haemophilus influenzae during development of competence for genetic transformation. J Bacteriol (1976) 1.33
The complete nucleotide sequence of bacteriophage HP1 DNA. Nucleic Acids Res (1996) 1.32
Factors influencing the specific interaction of Neisseria gonorrhoeae with transforming DNA. J Bacteriol (1991) 1.28
Site-specific integration of the Haemophilus influenzae bacteriophage HP1. Identification of the points of recombinational strand exchange and the limits of the host attachment site. J Biol Chem (1992) 1.28
Hydrophilic peptides derived from the transframe region of Gag-Pol inhibit the HIV-1 protease. Biochemistry (1998) 1.27
Structure-based mutagenesis of the catalytic domain of human immunodeficiency virus type 1 integrase. J Virol (1997) 1.27
Haemophilus influenzae and Neisseria gonorrhoeae recognize different specificity determinants in the DNA uptake step of genetic transformation. J Gen Microbiol (1982) 1.26
Melatonin biosynthesis: the structure of serotonin N-acetyltransferase at 2.5 A resolution suggests a catalytic mechanism. Mol Cell (1999) 1.26
Integration of the bacteriophage HP1c1 genome into the Haemophilus influenzae Rd chromosome in the lysogenic state. J Bacteriol (1986) 1.26
Site-specific integration of the Haemophilus influenzae bacteriophage HP1: location of the boundaries of the phage attachment site. J Bacteriol (1992) 1.23
On the role of pili in transformation of Neisseria gonorrhoeae. J Gen Microbiol (1984) 1.23
Multiple regulatory events in the development of competence for genetic transformation in Haemophilus influenzae. J Bacteriol (1975) 1.21
Purification and properties of cyclic phosphodiesterase: 3'-nucleotidase, a periplasmic enzyme of Haemophilus influenzae. Arch Biochem Biophys (1972) 1.20
Nucleotide sequence and expression of the gene for the site-specific integration protein from bacteriophage HP1 of Haemophilus influenzae. J Bacteriol (1989) 1.19
Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation. Proc Natl Acad Sci U S A (1996) 1.13
Location of the host attachment site for phage HPl within a cluster of Haemophilus influenzae tRNA genes. Nucleic Acids Res (1990) 1.12
Characterization of recognition sites on bacteriophage HP1c1 DNA which interact with the DNA uptake system of Haemophilus influenzae Rd. Gene (1984) 1.06
Nucleotide sequence and properties of the cohesive DNA termini from bacteriophage HP1c1 of Haemophilus influenzae Rd. Gene (1984) 1.05
The crystal structure of Pseudomonas aeruginosa exotoxin domain III with nicotinamide and AMP: conformational differences with the intact exotoxin. Proc Natl Acad Sci U S A (1995) 1.05
Reciprocal regulation of the early promoter region of bacteriophage HP1 by the Cox and Cl proteins. Virology (1997) 1.02
Restriction map and location of mutations on the genome of bacteriophage Hp1c1 of Haemophilus influenzae Rd. Gene (1983) 1.01
Haemophilus influenzae periplasmic protein which binds deoxyribonucleic acid: properties and possible participation in genetic transformation. J Bacteriol (1979) 1.01
Binding sites for bacteriophage HP1 integrase on its DNA substrates. J Biol Chem (1994) 1.00
Purification and characterization of HP1 Cox and definition of its role in controlling the direction of site-specific recombination. J Biol Chem (1997) 0.94
Identification of an HP1 phage protein required for site-specific excision. Mol Microbiol (1994) 0.93
Synchronous division and rates of macromolecular synthesis in Haemophilus influenzae competent for genetic transformation. J Bacteriol (1978) 0.92
14-3-3 proteins in pineal photoneuroendocrine transduction: how many roles? J Neuroendocrinol (2003) 0.90
Interaction of integration host factor from Escherichia coli with the integration region of the Haemophilus influenzae bacteriophage HP1. J Bacteriol (1990) 0.90
The crystal structure of bovine bile salt activated lipase: insights into the bile salt activation mechanism. Structure (1997) 0.90
Nucleotide sequence of cloned DNA segments of the Haemophilus influenzae bacteriophage HP1c1. Gene (1984) 0.89
14-3-3 Proteins and photoneuroendocrine transduction: role in controlling the daily rhythm in melatonin. Biochem Soc Trans (2002) 0.87
Site-specific recombination between cloned attP and attB sites from the Haemophilus influenzae bacteriophage HP1 propagated in recombination-deficient Escherichia coli. J Bacteriol (1989) 0.86
Purification and characterization of the integrase from the Haemophilus influenzae bacteriophage HP1; identification of a four-stranded intermediate and the order of strand exchange. Mol Microbiol (1996) 0.86
Protein and DNA requirements of the bacteriophage HP1 recombination system: a model for intasome formation. Nucleic Acids Res (2001) 0.86
Studies of deoxycytidylate deaminase from T4-infected Escherichia coli. J Biol Chem (1969) 0.84
DNA-binding proteins of Haemophilus influenzae: purification and characterization of a major intracellular binding protein. J Bacteriol (1983) 0.84
Phospholipids of Haemophilus influenzae Rd during exponential growth and following the development of competence for genetic transformation. J Gen Microbiol (1976) 0.84
Purification and substrate specificity of pyrimidine nucleoside phosphorylase from Haemophilus influenzae. J Biol Chem (1971) 0.82
Role of cysteines in the activation and inactivation of brewers' yeast pyruvate decarboxylase investigated with a PDC1-PDC6 fusion protein. Biochemistry (1993) 0.81
The IS200/IS605 Family and "Peel and Paste" Single-strand Transposition Mechanism. Microbiol Spectr (2015) 0.78
Pyrimidine nucleoside phosphorylase from Haemophilus influenzae. Methods Enzymol (1978) 0.77
Heterogeneity in recombinant HIV-1 integrase corrected by site-directed mutagenesis: the identification and elimination of a protease cleavage site. Protein Eng (1997) 0.76
A method of cloning multiple direct repeats of a DNA segment. Biotechniques (1993) 0.75
Direct methods with single isomorphous replacement data. I. Reduction of systematic errors. Acta Crystallogr A (1990) 0.75
Inhibition and release of respiration in particles from Alcaligenes faecalis. Arch Biochem Biophys (1968) 0.75
An evaluation of Tween 80 effects on the survival and DNA repair in Escherichia coli following UV or gamma irradiation. Mutat Res (1978) 0.75