PubRank

T M Lohman

Author PubWeight™ 113.17‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity. Q Rev Biophys 1978 9.44
2 Major domain swiveling revealed by the crystal structures of complexes of E. coli Rep helicase bound to single-stranded DNA and ADP. Cell 1997 4.71
3 A double-filter method for nitrocellulose-filter binding: application to protein-nucleic acid interactions. Proc Natl Acad Sci U S A 1993 4.00
4 Structure of the DNA binding domain of E. coli SSB bound to ssDNA. Nat Struct Biol 2000 3.34
5 Kinetic measurement of the step size of DNA unwinding by Escherichia coli UvrD helicase. Science 1997 3.21
6 Two binding modes in Escherichia coli single strand binding protein-single stranded DNA complexes. Modulation by NaCl concentration. J Biol Chem 1985 3.06
7 Crystal structure of the homo-tetrameric DNA binding domain of Escherichia coli single-stranded DNA-binding protein determined by multiwavelength x-ray diffraction on the selenomethionyl protein at 2.9-A resolution. Proc Natl Acad Sci U S A 1997 2.23
8 Interpretation of monovalent and divalent cation effects on the lac repressor-operator interaction. Biochemistry 1977 2.23
9 Large-scale overproduction and rapid purification of the Escherichia coli ssb gene product. Expression of the ssb gene under lambda PL control. Biochemistry 1986 2.20
10 Escherichia coli rep helicase unwinds DNA by an active mechanism. Biochemistry 1993 2.14
11 Allosteric effects of nucleotide cofactors on Escherichia coli Rep helicase-DNA binding. Science 1992 2.04
12 Nonspecific interaction of lac repressor with DNA: an association reaction driven by counterion release. Biochemistry 1977 1.95
13 Salt-dependent changes in the DNA binding co-operativity of Escherichia coli single strand binding protein. J Mol Biol 1986 1.94
14 Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases. Protein Sci 1998 1.93
15 Escherichia coli helicase II (uvrD) protein can completely unwind fully duplex linear and nicked circular DNA. J Biol Chem 1989 1.88
16 Escherichia coli single-strand binding protein forms multiple, distinct complexes with single-stranded DNA. Biochemistry 1986 1.86
17 Pentalysine-deoxyribonucleic acid interactions: a model for the general effects of ion concentrations on the interactions of proteins with nucleic acids. Biochemistry 1980 1.78
18 E. coli Rep oligomers are required to initiate DNA unwinding in vitro. J Mol Biol 2001 1.69
19 Nonspecific interactions of Escherichia coli RNA polymerase with native and denatured DNA: differences in the binding behavior of core and holoenzyme. Biochemistry 1978 1.67
20 Overexpression, purification, DNA binding, and dimerization of the Escherichia coli uvrD gene product (helicase II). Biochemistry 1993 1.60
21 DNA-induced dimerization of the Escherichia coli rep helicase. Allosteric effects of single-stranded and duplex DNA. J Biol Chem 1992 1.52
22 An oligomeric form of E. coli UvrD is required for optimal helicase activity. J Mol Biol 1999 1.51
23 DNA-induced dimerization of the Escherichia coli Rep helicase. J Mol Biol 1991 1.49
24 Equilibrium binding of Escherichia coli single-strand binding protein to single-stranded nucleic acids in the (SSB)65 binding mode. Cation and anion effects and polynucleotide specificity. Biochemistry 1988 1.46
25 Thermodynamic extent of counterion release upon binding oligolysines to single-stranded nucleic acids. Proc Natl Acad Sci U S A 1990 1.45
26 Thermodynamic methods for model-independent determination of equilibrium binding isotherms for protein-DNA interactions: spectroscopic approaches to monitor binding. Methods Enzymol 1991 1.42
27 Kinetics of protein-nucleic acid interactions: use of salt effects to probe mechanisms of interaction. CRC Crit Rev Biochem 1986 1.41
28 Binding mode transitions of Escherichia coli single strand binding protein-single-stranded DNA complexes. Cation, anion, pH, and binding density effects. J Biol Chem 1988 1.38
29 Co-operative binding of Escherichia coli SSB tetramers to single-stranded DNA in the (SSB)35 binding mode. J Mol Biol 1994 1.37
30 Na+ effects on transition of DNA and polynucleotides of variable linear charge density. Biopolymers 1976 1.36
31 Escherichia coli helicase II (UvrD) protein initiates DNA unwinding at nicks and blunt ends. Proc Natl Acad Sci U S A 1990 1.33
32 Single-turnover kinetics of helicase-catalyzed DNA unwinding monitored continuously by fluorescence energy transfer. Biochemistry 1994 1.28
33 Negative co-operativity in Escherichia coli single strand binding protein-oligonucleotide interactions. II. Salt, temperature and oligonucleotide length effects. J Mol Biol 1989 1.26
34 The importance of coulombic end effects: experimental characterization of the effects of oligonucleotide flanking charges on the strength and salt dependence of oligocation (L8+) binding to single-stranded DNA oligomers. Biophys J 1999 1.25
35 Apparent heat capacity change accompanying a nonspecific protein-DNA interaction. Escherichia coli SSB tetramer binding to oligodeoxyadenylates. Biochemistry 1994 1.24
36 Kinetics and mechanism of dissociation of cooperatively bound T4 gene 32 protein-single-stranded nucleic acid complexes. 1. Irreversible dissociation induced by sodium chloride concentration jumps. Biochemistry 1984 1.24
37 Kinetics and mechanism of the association of the bacteriophage T4 gene 32 (helix destabilizing) protein with single-stranded nucleic acids. Evidence for protein translocation. J Mol Biol 1981 1.22
38 Calorimetric studies of E. coli SSB protein-single-stranded DNA interactions. Effects of monovalent salts on binding enthalpy. J Mol Biol 1998 1.21
39 A general method of analysis of ligand-macromolecule equilibria using a spectroscopic signal from the ligand to monitor binding. Application to Escherichia coli single-strand binding protein-nucleic acid interactions. Biochemistry 1987 1.17
40 Limited co-operativity in protein-nucleic acid interactions. A thermodynamic model for the interactions of Escherichia coli single strand binding protein with single-stranded nucleic acids in the "beaded", (SSB)65 mode. J Mol Biol 1987 1.16
41 Negative co-operativity in Escherichia coli single strand binding protein-oligonucleotide interactions. I. Evidence and a quantitative model. J Mol Biol 1989 1.16
42 Adenine base unstacking dominates the observed enthalpy and heat capacity changes for the Escherichia coli SSB tetramer binding to single-stranded oligoadenylates. Biochemistry 1999 1.15
43 E. coli single strand binding protein: a new look at helix-destabilizing proteins. Trends Biochem Sci 1988 1.15
44 Linkage of pH, anion and cation effects in protein-nucleic acid equilibria. Escherichia coli SSB protein-single stranded nucleic acid interactions. J Mol Biol 1994 1.14
45 Large contributions of coupled protonation equilibria to the observed enthalpy and heat capacity changes for ssDNA binding to Escherichia coli SSB protein. Proteins 2000 1.11
46 Monomer-tetramer equilibrium of the Escherichia coli ssb-1 mutant single strand binding protein. J Biol Chem 1991 1.10
47 Thermodynamics of single-stranded RNA binding to oligolysines containing tryptophan. Biochemistry 1992 1.09
48 Thermodynamics of single-stranded RNA and DNA interactions with oligolysines containing tryptophan. Effects of base composition. Biochemistry 1993 1.05
49 Thermodynamics of oligoarginines binding to RNA and DNA. Biochemistry 1997 1.04
50 On the cooperative binding of large ligands to a one-dimensional homogeneous lattice: the generalized three-state lattice model. Biopolymers 1989 1.04
51 Large electrostatic differences in the binding thermodynamics of a cationic peptide to oligomeric and polymeric DNA. Proc Natl Acad Sci U S A 1996 1.02
52 DNA and nucleotide-induced conformational changes in the Escherichia coli Rep and helicase II (UvrD) proteins. J Biol Chem 1990 1.01
53 Analysis of ion concentration effects of the kinetics of protein-nucleic acid interactions. Application to lac repressor-operator interactions. Biophys Chem 1978 0.99
54 A two-site kinetic mechanism for ATP binding and hydrolysis by E. coli Rep helicase dimer bound to a single-stranded oligodeoxynucleotide. J Mol Biol 1999 0.98
55 Kinetic mechanism of DNA binding and DNA-induced dimerization of the Escherichia coli Rep helicase. Biochemistry 1996 0.97
56 Linkage of protein assembly to protein-DNA binding. Methods Enzymol 1995 0.97
57 Kinetic mechanism of adenine nucleotide binding to and hydrolysis by the Escherichia coli Rep monomer. 1. Use of fluorescent nucleotide analogues. Biochemistry 1994 0.97
58 Monomers of the Escherichia coli SSB-1 mutant protein bind single-stranded DNA. J Mol Biol 1991 0.94
59 Thermodynamics of charged oligopeptide-heparin interactions. Biochemistry 1995 0.93
60 Cooperative binding of polyamines induces the Escherichia coli single-strand binding protein-DNA binding mode transitions. Biochemistry 1992 0.93
61 ATP hydrolysis stimulates binding and release of single stranded DNA from alternating subunits of the dimeric E. coli Rep helicase: implications for ATP-driven helicase translocation. J Mol Biol 1996 0.92
62 ATPase activity of Escherichia coli Rep helicase is dramatically dependent on DNA ligation and protein oligomeric states. Biochemistry 1996 0.91
63 Kinetic mechanism of adenine nucleotide binding to and hydrolysis by the Escherichia coli Rep monomer. 2. Application of a kinetic competition approach. Biochemistry 1994 0.89
64 Kinetics of Escherichia coli helicase II-catalyzed unwinding of fully duplex and nicked circular DNA. Biochemistry 1993 0.89
65 Heterodimer formation between Escherichia coli Rep and UvrD proteins. J Biol Chem 1993 0.88
66 Model for the irreversible dissociation kinetics of cooperatively bound protein-nucleic acid complexes. Biopolymers 1983 0.87
67 A two-site mechanism for ATP hydrolysis by the asymmetric Rep dimer P2S as revealed by site-specific inhibition with ADP-A1F4. Biochemistry 1997 0.87
68 Helicase-catalyzed DNA unwinding: energy coupling by DNA motor proteins. Biophys J 1995 0.85
69 Use of difference boundary sedimentation velocity to investigate nonspecific protein-nucleic acid interactions. Biochemistry 1980 0.85
70 A mutation in E. coli SSB protein (W54S) alters intra-tetramer negative cooperativity and inter-tetramer positive cooperativity for single-stranded DNA binding. Biophys Chem 1997 0.83
71 Kinetics and mechanism of dissociation of cooperatively bound T4 gene 32 protein-single-stranded nucleic acid complexes. 2. Changes in mechanism as a function of sodium chloride concentration and other solution variables. Biochemistry 1984 0.82
72 Iron(II)-ethylenediaminetetraacetic acid catalyzed cleavage of DNA is highly specific for duplex DNA. Biochemistry 1989 0.81
73 Kinetics of the t4 gene 32 protein-single-stranded nucleic Acid interaction. Biophys J 1980 0.79
74 Kinetic mechanism for the sequential binding of two single-stranded oligodeoxynucleotides to the Escherichia coli Rep helicase dimer. Biochemistry 1998 0.78
75 ATPase activity of Escherichia coli Rep helicase crosslinked to single-stranded DNA: implications for ATP driven helicase translocation. Proc Natl Acad Sci U S A 1996 0.77