Published in Genetics on May 01, 1997
Creation of low-copy integrated transgenic lines in Caenorhabditis elegans. Genetics (2001) 10.29
A Dicer-like protein in Tetrahymena has distinct functions in genome rearrangement, chromosome segregation, and meiotic prophase. Genes Dev (2004) 2.75
MEC-17 is an alpha-tubulin acetyltransferase. Nature (2010) 2.64
A robust inducible-repressible promoter greatly facilitates gene knockouts, conditional expression, and overexpression of homologous and heterologous genes in Tetrahymena thermophila. Proc Natl Acad Sci U S A (2002) 2.46
RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena. Genes Dev (2007) 2.26
Conjugation-specific small RNAs in Tetrahymena have predicted properties of scan (scn) RNAs involved in genome rearrangement. Genes Dev (2004) 2.19
Microarray analyses of gene expression during the Tetrahymena thermophila life cycle. PLoS One (2009) 2.11
Histone H3 lysine 9 methylation is required for DNA elimination in developing macronuclei in Tetrahymena. Proc Natl Acad Sci U S A (2004) 2.10
Germ line transcripts are processed by a Dicer-like protein that is essential for developmentally programmed genome rearrangements of Tetrahymena thermophila. Mol Cell Biol (2005) 2.06
Holoenzyme proteins required for the physiological assembly and activity of telomerase. Genes Dev (2004) 1.86
2'-O-methylation stabilizes Piwi-associated small RNAs and ensures DNA elimination in Tetrahymena. RNA (2009) 1.76
Katanin regulates dynamics of microtubules and biogenesis of motile cilia. J Cell Biol (2007) 1.54
Polyglycylation of tubulin is essential and affects cell motility and division in Tetrahymena thermophila. J Cell Biol (2000) 1.43
Tetrahymena thermophila contains a conventional gamma-tubulin that is differentially required for the maintenance of different microtubule-organizing centers. J Cell Biol (2002) 1.42
Refined annotation and assembly of the Tetrahymena thermophila genome sequence through EST analysis, comparative genomic hybridization, and targeted gap closure. BMC Genomics (2008) 1.40
Kinesin-II is preferentially targeted to assembling cilia and is required for ciliogenesis and normal cytokinesis in Tetrahymena. Mol Biol Cell (1999) 1.37
Excision of micronuclear-specific DNA requires parental expression of pdd2p and occurs independently from DNA replication in Tetrahymena thermophila. Genes Dev (1999) 1.36
Deposition and function of histone H3 variants in Tetrahymena thermophila. Mol Cell Biol (2006) 1.22
Glutamylation on alpha-tubulin is not essential but affects the assembly and functions of a subset of microtubules in Tetrahymena thermophila. Eukaryot Cell (2008) 1.20
G-overhang dynamics at Tetrahymena telomeres. EMBO J (2001) 1.17
Tetrahymena ORC contains a ribosomal RNA fragment that participates in rDNA origin recognition. EMBO J (2007) 1.11
Different effects of Tetrahymena IFT172 domains on anterograde and retrograde intraflagellar transport. Mol Biol Cell (2008) 1.09
Nucleus-specific importin alpha proteins and nucleoporins regulate protein import and nuclear division in the binucleate Tetrahymena thermophila. Eukaryot Cell (2008) 1.09
Constitutive expression, not a particular primary sequence, is the important feature of the H3 replacement variant hv2 in Tetrahymena thermophila. Mol Cell Biol (1997) 1.08
Hypoxia regulates assembly of cilia in suppressors of Tetrahymena lacking an intraflagellar transport subunit gene. Mol Biol Cell (2003) 1.07
The CNA1 histone of the ciliate Tetrahymena thermophila is essential for chromosome segregation in the germline micronucleus. Mol Biol Cell (2005) 1.05
Elimination of foreign DNA during somatic differentiation in Tetrahymena thermophila shows position effect and is dosage dependent. Eukaryot Cell (2005) 1.04
The nonessential H2A N-terminal tail can function as an essential charge patch on the H2A.Z variant N-terminal tail. Mol Cell Biol (2003) 1.02
RNA polymerase II localizes in Tetrahymena thermophila meiotic micronuclei when micronuclear transcription associated with genome rearrangement occurs. Eukaryot Cell (2004) 1.02
Lia1p, a novel protein required during nuclear differentiation for genome-wide DNA rearrangements in Tetrahymena thermophila. Eukaryot Cell (2007) 0.99
RAD51 is required for propagation of the germinal nucleus in Tetrahymena thermophila. Genetics (2000) 0.99
DNA double-strand breaks, but not crossovers, are required for the reorganization of meiotic nuclei in Tetrahymena. J Cell Sci (2008) 0.99
Positive and negative regulation of Tetrahymena telomerase holoenzyme. Mol Cell Biol (2007) 0.99
Centromeric histone H3 is essential for vegetative cell division and for DNA elimination during conjugation in Tetrahymena thermophila. Mol Cell Biol (2006) 0.98
Gene knockouts reveal separate functions for two cytoplasmic dyneins in Tetrahymena thermophila. Mol Biol Cell (1999) 0.97
DYF-1 Is required for assembly of the axoneme in Tetrahymena thermophila. Eukaryot Cell (2009) 0.96
Mutational analyses reveal a novel function of the nucleotide-binding domain of gamma-tubulin in the regulation of basal body biogenesis. J Cell Biol (2005) 0.96
Phosphorylation of the SQ H2A.X motif is required for proper meiosis and mitosis in Tetrahymena thermophila. Mol Cell Biol (2007) 0.95
Analysis of exocytosis mutants indicates close coupling between regulated secretion and transcription activation in Tetrahymena. Proc Natl Acad Sci U S A (1997) 0.95
The conjugation-specific Die5 protein is required for development of the somatic nucleus in both Paramecium and Tetrahymena. Eukaryot Cell (2010) 0.94
MRE11 and COM1/SAE2 are required for double-strand break repair and efficient chromosome pairing during meiosis of the protist Tetrahymena. Chromosoma (2010) 0.93
The germ line limited M element of Tetrahymena is targeted for elimination from the somatic genome by a homology-dependent mechanism. Nucleic Acids Res (2006) 0.93
Modulation of telomere length dynamics by the subtelomeric region of tetrahymena telomeres. Mol Biol Cell (2004) 0.93
The two domains of centrin have distinct basal body functions in Tetrahymena. Mol Biol Cell (2011) 0.93
Proteolytic processing and Ca2+-binding activity of dense-core vesicle polypeptides in Tetrahymena. Mol Biol Cell (1998) 0.92
TIF1 Represses rDNA replication initiation, but promotes normal S phase progression and chromosome transmission in Tetrahymena. Mol Biol Cell (2005) 0.91
Tetrahymena meiotic nuclear reorganization is induced by a checkpoint kinase-dependent response to DNA damage. Mol Biol Cell (2009) 0.91
The actin gene ACT1 is required for phagocytosis, motility, and cell separation of Tetrahymena thermophila. Eukaryot Cell (2006) 0.90
An unusual fibrillarin gene and protein: structure and functional implications. Mol Biol Cell (1997) 0.90
A nonessential HP1-like protein affects starvation-induced assembly of condensed chromatin and gene expression in macronuclei of Tetrahymena thermophila. Mol Cell Biol (1999) 0.90
TIF1 activates the intra-S-phase checkpoint response in the diploid micronucleus and amitotic polyploid macronucleus of Tetrahymena. Mol Biol Cell (2006) 0.90
Gene network landscape of the ciliate Tetrahymena thermophila. PLoS One (2011) 0.88
Modules for C-terminal epitope tagging of Tetrahymena genes. J Microbiol Methods (2010) 0.88
ε-tubulin is essential in Tetrahymena thermophila for the assembly and stability of basal bodies. J Cell Sci (2013) 0.88
A knockout mutation of a constitutive GPCR in Tetrahymena decreases both G-protein activity and chemoattraction. PLoS One (2011) 0.87
Zygotic expression of the double-stranded RNA binding motif protein Drb2p is required for DNA elimination in the ciliate Tetrahymena thermophila. Eukaryot Cell (2011) 0.87
LIA5 is required for nuclear reorganization and programmed DNA rearrangements occurring during tetrahymena macronuclear differentiation. PLoS One (2013) 0.87
Whole-cell biosensors for detection of heavy metal ions in environmental samples based on metallothionein promoters from Tetrahymena thermophila. Microb Biotechnol (2011) 0.87
The transition from conjugal development to the first vegetative cell division is dependent on RAD51 expression in the ciliate Tetrahymena thermophila. Genetics (2001) 0.86
The two human centrin homologues have similar but distinct functions at Tetrahymena basal bodies. Mol Biol Cell (2012) 0.85
Biochemical and molecular characterisation of Tetrahymena thermophila extracellular cysteine proteases. BMC Microbiol (2006) 0.85
Histone H2B ubiquitylation is not required for histone H3 methylation at lysine 4 in tetrahymena. J Biol Chem (2009) 0.85
A developmentally regulated gene, ASI2, is required for endocycling in the macronuclear anlagen of Tetrahymena. Eukaryot Cell (2010) 0.85
A single cohesin complex performs mitotic and meiotic functions in the protist tetrahymena. PLoS Genet (2013) 0.85
Endoplasmic reticulum retention signal-dependent glycylation of the Hsp70/Grp170-related Pgp1p in Tetrahymena. Eukaryot Cell (2006) 0.85
The zinc finger protein Zfr1p is localized specifically to conjugation junction and required for sexual development in Tetrahymena thermophila. PLoS One (2012) 0.84
Role of ATG8 and autophagy in programmed nuclear degradation in Tetrahymena thermophila. Eukaryot Cell (2012) 0.84
New class of cargo protein in Tetrahymena thermophila dense core secretory granules. Eukaryot Cell (2002) 0.84
Septins stabilize mitochondria in Tetrahymena thermophila. Eukaryot Cell (2008) 0.83
Establishment of a Cre/loxP recombination system for N-terminal epitope tagging of genes in Tetrahymena. BMC Microbiol (2010) 0.83
Lysosomal sorting receptors are essential for secretory granule biogenesis in Tetrahymena. J Cell Biol (2013) 0.82
Independent transport and sorting of functionally distinct protein families in Tetrahymena thermophila dense core secretory granules. Eukaryot Cell (2009) 0.82
CCTalpha and CCTdelta chaperonin subunits are essential and required for cilia assembly and maintenance in Tetrahymena. PLoS One (2010) 0.82
A recombinase system facilitates cloning of expression cassettes in the ciliate Tetrahymena thermophila. BMC Microbiol (2007) 0.81
Quantitative proteomics reveals that the specific methyltransferases Txr1p and Ezl2p differentially affect the mono-, di- and trimethylation states of histone H3 lysine 27 (H3K27). Mol Cell Proteomics (2012) 0.81
The bifunctional dihydrofolate reductase thymidylate synthase of Tetrahymena thermophila provides a tool for molecular and biotechnology applications. BMC Biotechnol (2006) 0.81
Class I histone deacetylase Thd1p affects nuclear integrity in Tetrahymena thermophila. Eukaryot Cell (2005) 0.80
Unphosphorylated H1 is enriched in a specific region of the promoter when CDC2 is down-regulated during starvation. Mol Cell Biol (2006) 0.80
Characterization of TtALV2, an essential charged repeat motif protein of the Tetrahymena thermophila membrane skeleton. Eukaryot Cell (2013) 0.80
C-5(6) sterol desaturase from tetrahymena thermophila: Gene identification and knockout, sequence analysis, and comparison to other C-5(6) sterol desaturases. Eukaryot Cell (2009) 0.80
Mutations in Pdd1 reveal distinct requirements for its chromodomain and chromoshadow domain in directing histone methylation and heterochromatin elimination. Eukaryot Cell (2013) 0.79
Tetrahymena in the laboratory: strain resources, methods for culture, maintenance, and storage. Methods Cell Biol (2012) 0.79
Deletion of the Tetrahymena thermophila rDNA replication fork barrier region disrupts macronuclear rDNA excision and creates a fragile site in the micronuclear genome. Nucleic Acids Res (2006) 0.79
The nonhistone, N-terminal tail of an essential, chimeric H2A variant regulates mitotic H3-S10 dephosphorylation. Genes Dev (2012) 0.79
LIA4 encodes a chromoshadow domain protein required for genomewide DNA rearrangements in Tetrahymena thermophila. Eukaryot Cell (2014) 0.79
Secretion of Polypeptide Crystals from Tetrahymena thermophila Secretory Organelles (Mucocysts) Depends on Processing by a Cysteine Cathepsin, Cth4p. Eukaryot Cell (2015) 0.79
An aspartyl cathepsin, CTH3, is essential for proprotein processing during secretory granule maturation in Tetrahymena thermophila. Mol Biol Cell (2014) 0.78
Tetrahymena as a Unicellular Model Eukaryote: Genetic and Genomic Tools. Genetics (2016) 0.78
Quantitative proteomics reveals histone modifications in crosstalk with H3 lysine 27 methylation. Mol Cell Proteomics (2014) 0.78
A novel sterol desaturase-like protein promoting dealkylation of phytosterols in Tetrahymena thermophila. Eukaryot Cell (2011) 0.78
Expression, secretion and surface display of a human alkaline phosphatase by the ciliate Tetrahymena thermophila. BMC Biotechnol (2011) 0.78
Targeted Gene Disruption by Ectopic Induction of DNA Elimination in Tetrahymena. Genetics (2015) 0.78
Molecular genetic analysis of an SNF2/brahma-related gene in Tetrahymena thermophila suggests roles in growth and nuclear development. Eukaryot Cell (2006) 0.77
Chromodomain protein Tcd1 is required for macronuclear genome rearrangement and repair in Tetrahymena. Sci Rep (2015) 0.77
A novel malaria vaccine candidate antigen expressed in Tetrahymena thermophila. PLoS One (2014) 0.77
The cytochrome b5 dependent C-5(6) sterol desaturase DES5A from the endoplasmic reticulum of Tetrahymena thermophila complements ergosterol biosynthesis mutants in Saccharomyces cerevisiae. Steroids (2012) 0.77
The CSC proteins FAP61 and FAP251 build the basal substructures of radial spoke 3 in cilia. Mol Biol Cell (2015) 0.76
Two Tetrahymena G-DNA-binding proteins, TGP1 and TGP3, share novel motifs and may play a role in micronuclear division. Nucleic Acids Res (2000) 0.76
Tetrahymena: the key to the genetic analysis of the regulated pathway of polypeptide secretion? Proc Natl Acad Sci U S A (1997) 0.76
Kin5 knockdown in Tetrahymena thermophila using RNAi blocks cargo transport of Gef1. PLoS One (2009) 0.76
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