Published in J Biochem on August 01, 1977
The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: a map of ten nonrepetitive epitopes starting at the Z line extends close to the M line. J Cell Biol (1988) 3.86
The mechanical stability of immunoglobulin and fibronectin III domains in the muscle protein titin measured by atomic force microscopy. Biophys J (1998) 2.90
A network of transverse and longitudinal intermediate filaments is associated with sarcomeres of adult vertebrate skeletal muscle. J Cell Biol (1983) 2.16
Nature of PEVK-titin elasticity in skeletal muscle. Proc Natl Acad Sci U S A (1998) 1.94
Connectin filaments link thick filaments and Z lines in frog skeletal muscle as revealed by immunoelectron microscopy. J Cell Biol (1985) 1.83
Molecular structure of the sarcomeric Z-disk: two types of titin interactions lead to an asymmetrical sorting of alpha-actinin. EMBO J (1998) 1.78
The NH2 terminus of titin spans the Z-disc: its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrity. J Cell Biol (1998) 1.78
Visualization of the polarity of isolated titin molecules: a single globular head on a long thin rod as the M band anchoring domain? J Cell Biol (1989) 1.69
A new 400-kD protein from isolated adherens junctions: its localization at the undercoat of adherens junctions and at microfilament bundles such as stress fibers and circumferential bundles. J Cell Biol (1989) 1.61
Strain of passive elements during force enhancement by stretch in frog muscle fibres. J Physiol (1996) 1.55
Thermal stress and Ca-independent contractile activation in mammalian skeletal muscle fibers at high temperatures. Biophys J (1994) 1.47
Flexible mechanisms: the diverse roles of biological springs in vertebrate movement. J Exp Biol (2011) 1.41
Actin-titin interaction in cardiac myofibrils: probing a physiological role. Biophys J (1997) 1.36
The elasticity of relaxed insect fibrillar flight muscle. J Physiol (1983) 1.36
Stretch and radial compression studies on relaxed skinned muscle fibers of the frog. Biophys J (1979) 1.33
Monoclonal antibodies distinguish titins from heart and skeletal muscle. J Cell Biol (1986) 1.32
Elastic behavior of connectin filaments during thick filament movement in activated skeletal muscle. J Cell Biol (1989) 1.32
Characterization of beta-connectin (titin 2) from striated muscle by dynamic light scattering. Biophys J (1993) 1.25
Connectin filaments in stretched skinned fibers of frog skeletal muscle. J Cell Biol (1984) 1.22
Does actin bind to the ends of thin filaments in skeletal muscle? J Cell Biol (1985) 1.13
Incorporation of nascent myosin heavy chains into thick filaments of cardiac myocytes in thyroid-treated rabbits. J Cell Biol (1987) 1.05
Hydrostatic compression in glycerinated rabbit muscle fibers. Biophys J (1990) 1.04
Thick-filament strain and interfilament spacing in passive muscle: effect of titin-based passive tension. Biophys J (2011) 0.99
A new high molecular mass protein showing unique localization in desmosomal plaque. J Cell Biol (1989) 0.88
The non-linear elasticity of the muscle sarcomere and the compliance of myosin motors. J Physiol (2013) 0.87
Is the SII portion of the cross-bridge in glycerinated rabbit psoas fibers compliant in the rigor state? Biophys J (1984) 0.87
Stability and folding rates of domains spanning the large A-band super-repeat of titin. Biophys J (2001) 0.85
Lattice swelling with the selective digestion of elastic components in single-skinned fibers of frog muscle. Biophys J (1987) 0.85
In situ reconstitution of myosin filaments within the myosin-extracted myofibril in cultured skeletal muscle cells. J Cell Biol (1982) 0.84
Early mechanical dysfunction of the diaphragm in the muscular dystrophy with myositis (Ttnmdm) model. Am J Physiol Cell Physiol (2008) 0.82
Forgotten research from 19th century: science should not follow fashion. J Muscle Res Cell Motil (2014) 0.78
Historical perspective on heart function: the Frank-Starling Law. Biophys Rev (2015) 0.75
Nuances of electrophoresis study of titin/connectin. Biophys Rev (2017) 0.75
A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature (1988) 27.60
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med (2001) 16.51
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med (2002) 14.15
The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci U S A (1989) 7.41
Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature (1991) 7.11
Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor. Science (1995) 6.03
Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes. FEBS Lett (1990) 5.14
Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N Engl J Med (1993) 4.91
Detection of calcium binding proteins by 45Ca autoradiography on nitrocellulose membrane after sodium dodecyl sulfate gel electrophoresis. J Biochem (1984) 4.69
Expression of cyclooxygenase-1 and -2 in human colorectal cancer. Cancer Res (1995) 4.52
The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice. Nat Med (1998) 4.48
Biological profiles of highly potent novel endothelin antagonists selective for the ETA receptor. Life Sci (1992) 4.39
Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum. Development (1999) 4.26
Progress in gastric cancer surgery in Japan and its limits of radicality. World J Surg (1987) 4.06
Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. Gene (1997) 4.02
Evaluation of acridinium-ester-labeled DNA probes for identification of Mycobacterium tuberculosis and Mycobacterium avium-Mycobacterium intracellulare complex in culture. J Clin Microbiol (1991) 3.88
Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J Biol Chem (1993) 3.88
Characterization of the common genetic defect in humans deficient in debrisoquine metabolism. Nature (1988) 3.69
Cloning of an interleukin-3 receptor gene: a member of a distinct receptor gene family. Science (1990) 3.35
Regulation of the phosphate regulon of Escherichia coli. Activation of pstS transcription by PhoB protein in vitro. J Mol Biol (1988) 3.14
Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene. J Biol Chem (2000) 3.11
Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia. Diabetes (2000) 3.01
Human thyroid peroxidase: complete cDNA and protein sequence, chromosome mapping, and identification of two alternately spliced mRNAs. Proc Natl Acad Sci U S A (1987) 3.00
Primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide. Proc Natl Acad Sci U S A (1988) 2.99
Cleft palate and decreased brain gamma-aminobutyric acid in mice lacking the 67-kDa isoform of glutamic acid decarboxylase. Proc Natl Acad Sci U S A (1997) 2.91
Recurrence of early gastric cancer. Follow-up of 1475 patients and review of the Japanese literature. Cancer (1993) 2.90
Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values. J Pharmacol Exp Ther (1989) 2.78
Clonal isolation of muscle-derived cells capable of enhancing muscle regeneration and bone healing. J Cell Biol (2000) 2.75
Adenovirus E1A coding sequences that enable ras and pmt oncogenes to transform cultured primary cells. Mol Cell Biol (1986) 2.70
The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance. J Biol Chem (2001) 2.69
Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos. Dev Biol (1999) 2.69
Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter. Mol Cell Biol (2001) 2.68
Localization of allodeterminants on H-2Kb antigens determined with monoclonal antibodies and H-2 mutant mice. Proc Natl Acad Sci U S A (1982) 2.33
Characteristics of Ca2+- and Mg2+-induced tension development in chemically skinned smooth muscle fibers. J Gen Physiol (1978) 2.29
Beta-catenin mutation in carcinoma of the uterine endometrium. Cancer Res (1998) 2.27
Retracted Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha. Mol Cell Biol (1999) 2.25
Positive inotropic action of novel vasoconstrictor peptide endothelin on guinea pig atria. Am J Physiol (1988) 2.18
Frequent presence of HBV in the sera of HBsAg-negative, anti-HBc-positive blood donors. Transfusion (2001) 2.16
Nodeless superconducting gap in A(x)Fe2Se2 (A=K,Cs) revealed by angle-resolved photoemission spectroscopy. Nat Mater (2011) 2.16
In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes. Cell (1986) 2.13
Ca2+ control of actin filament length. Effects of macrophage gelsolin on actin polymerization. J Biol Chem (1981) 2.07
Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells. Genes Dev (1997) 2.03
An outbreak of enteritis due to Yersinia enterocolitica occurring at a junior high school. Jpn J Microbiol (1973) 2.02
Activity of amphipathic poly(ethylene glycol) 5000 to prolong the circulation time of liposomes depends on the liposome size and is unfavorable for immunoliposome binding to target. Biochim Biophys Acta (1991) 2.01
Molecular and functional analysis of the mariner mutator element Mos1 in Drosophila. Genetics (1991) 2.00
Neuropathological features of Japanese familial amyotrophic lateral sclerosis with p.N352S mutation in TARDBP. Neuropathol Appl Neurobiol (2014) 1.99
Measurement of soil contamination by radionuclides due to the Fukushima Dai-ichi Nuclear Power Plant accident and associated estimated cumulative external dose estimation. J Environ Radioact (2011) 1.98
Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes. J Clin Invest (2001) 1.97
DNA binding of PhoB and its interaction with RNA polymerase. J Mol Biol (1996) 1.97
New method to evaluate the therapeutic value of lymph node dissection for gastric cancer. Br J Surg (1995) 1.96
Disruption of the DT diaphorase (NQO1) gene in mice leads to increased menadione toxicity. J Biol Chem (1998) 1.94
Structure and regulation of the Escherichia coli ruv operon involved in DNA repair and recombination. J Bacteriol (1988) 1.92
Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocarcinogenesis. Cancer Res (2001) 1.91
The Pro12Ala polymorphism in PPAR gamma2 may confer resistance to type 2 diabetes. Biochem Biophys Res Commun (2000) 1.91
Successful screening for early esophageal cancer in alcoholics using endoscopy and mucosa iodine staining. Cancer (1995) 1.91
Amino acid sequence of an amyloid fibril protein of unknown origin. J Biol Chem (1972) 1.90
Molecular and cellular mechanism of endothelin regulation. Implications for vascular function. Circulation (1991) 1.86
Connectin, an elastic filamentous protein of striated muscle. Int Rev Cytol (1986) 1.84
A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes. Diabetologia (2002) 1.83
Connectin filaments link thick filaments and Z lines in frog skeletal muscle as revealed by immunoelectron microscopy. J Cell Biol (1985) 1.83
Evaluation of the therapeutic effect of radiotherapy on cervical cancer using magnetic resonance imaging. Int J Radiat Oncol Biol Phys (1999) 1.82
Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases. J Biol Chem (2001) 1.82
An about 50,000-dalton protein in adrenal medulla: a common precursor of [Met]- and [Leu]enkephalin. Science (1980) 1.81
Real-time automated PCR for early diagnosis and monitoring of cytomegalovirus infection after bone marrow transplantation. J Clin Microbiol (2000) 1.80
Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintain normal levels of GAD67 and GABA in their brains but are susceptible to seizures. Biochem Biophys Res Commun (1996) 1.79
Comparison of the flanking regions and introns of the mouse 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P1-450 and P3-450 genes. J Biol Chem (1985) 1.79
A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini. J Biol Chem (1992) 1.79
Myosin-actin interaction plays an important role in human immunodeficiency virus type 1 release from host cells. Proc Natl Acad Sci U S A (1995) 1.79
Silk fibroin of Bombyx mori is secreted, assembling a high molecular mass elementary unit consisting of H-chain, L-chain, and P25, with a 6:6:1 molar ratio. J Biol Chem (2000) 1.78
Evaluation of the New International Union Against Cancer TNM staging for gastric carcinoma. Cancer (2000) 1.77
The murine Ah locus. Comparison of the complete cytochrome P1-450 and P3-450 cDNA nucleotide and amino acid sequences. J Biol Chem (1984) 1.75
Electron microscopic particle length of F-actin polymerized in vitro. J Biochem (1970) 1.75
Amylase concentration of drainage fluid after total gastrectomy. Br J Surg (1997) 1.71
Transactivation of the multidrug resistance 1 gene by T-cell factor 4/beta-catenin complex in early colorectal carcinogenesis. Cancer Res (2000) 1.71
Complete nucleotide sequence of the prophage VT2-Sakai carrying the verotoxin 2 genes of the enterohemorrhagic Escherichia coli O157:H7 derived from the Sakai outbreak. Genes Genet Syst (1999) 1.70
Simple and rapid purification of brevin. Biochem Biophys Res Commun (1990) 1.70
Chronic subdural hematoma, as an initial manifestation of glutaric aciduria type-1. Brain Dev (1993) 1.70
Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics. Carcinogenesis (1998) 1.70
Flow cytometric single-cell analysis of cytokine production by CD4+ T cells in synovial tissue and peripheral blood from patients with rheumatoid arthritis. Arthritis Rheum (1998) 1.69
Use of real-time PCR on blood samples for diagnosis of invasive aspergillosis. Clin Infect Dis (2001) 1.69
The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue. Proc Natl Acad Sci U S A (1997) 1.69
Periodic distribution of troponin along the thin filament. J Biochem (1967) 1.69
Formation of Rathke's pouch requires dual induction from the diencephalon. Development (1998) 1.68
Effects of endothelin on the renal artery from spontaneously hypertensive and Wistar Kyoto rats. Eur J Pharmacol (1988) 1.68
Structure and regulation of rat long-chain acyl-CoA synthetase. J Biol Chem (1990) 1.68
Muscle-specific calpain, p94, responsible for limb girdle muscular dystrophy type 2A, associates with connectin through IS2, a p94-specific sequence. J Biol Chem (1995) 1.68
Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos. Dev Dyn (2000) 1.67
Probable assignment of soluble isocitrate dehydrogenase (IDH1) to 2q33.3. Hum Genet (1985) 1.66
Retracted Angiotensin AT(1) and AT(2) receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF)-mediated EGF receptor transactivation. Circ Res (2001) 1.64
Essential role of insulin receptor substrate 1 (IRS-1) and IRS-2 in adipocyte differentiation. Mol Cell Biol (2001) 1.62
Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon. Development (2001) 1.62
Detection of Pneumocystis carinii sequences by polymerase chain reaction: animal models and clinical application to noninvasive specimens. J Clin Microbiol (1991) 1.60
Involvement of endothelin in the regulation of human vascular tonus. Potent vasoconstrictor effect and existence in endothelial cells. Circulation (1990) 1.59
Endothelin activates the dihydropyridine-sensitive, voltage-dependent Ca2+ channel in vascular smooth muscle. Proc Natl Acad Sci U S A (1989) 1.58
Detection of Toxoplasma gondii, Epstein-Barr virus, and JC virus DNAs in the cerebrospinal fluid in acquired immunodeficiency syndrome patients with focal central nervous system complications. Intern Med (1999) 1.57
Crystal structure of ribonuclease H from Thermus thermophilus HB8 refined at 2.8 A resolution. J Mol Biol (1993) 1.57
Hyperthyroidism presenting as dysphagia. Intern Med (2000) 1.57