Polymorphisms of alpha-adducin and salt sensitivity in patients with essential hypertension.

PubWeight™: 2.78‹?› | Rank: Top 1%

🔗 View Article (PMID 9149697)

Published in Lancet on May 10, 1997

Authors

D Cusi1, C Barlassina, T Azzani, G Casari, L Citterio, M Devoto, N Glorioso, C Lanzani, P Manunta, M Righetti, R Rivera, P Stella, C Troffa, L Zagato, G Bianchi

Author Affiliations

1: Postgraduate School of Nephrology, University of Milan, Italy.

Articles citing this

In silico functional profiling of human disease-associated and polymorphic amino acid substitutions. Hum Mutat (2010) 1.81

Upregulation of Na+/Ca2+ exchanger and TRPC6 contributes to abnormal Ca2+ homeostasis in arterial smooth muscle cells from Milan hypertensive rats. Am J Physiol Heart Circ Physiol (2010) 1.77

Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic. Hypertension (2008) 1.66

Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat. Cell (2013) 1.53

TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives. J Hypertens (2015) 1.43

Genome-wide data from two early Neolithic East Asian individuals dating to 7700 years ago. Sci Adv (2017) 1.39

Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide. Hypertension (2013) 1.14

Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension. BMC Med Genet (2005) 1.01

Genetics of arterial hypertension and hypotension. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.97

Novel genetic variants in the alpha-adducin and guanine nucleotide binding protein beta-polypeptide 3 genes and salt sensitivity of blood pressure. Am J Hypertens (2009) 0.97

Relationships among endogenous ouabain, alpha-adducin polymorphisms and renal sodium handling in primary hypertension. J Hypertens (2008) 0.97

The role of the kidney in regulating arterial blood pressure. Nat Rev Nephrol (2012) 0.94

Alpha-adducin Gly460Trp polymorphism and hypertension risk: a meta-analysis of 22 studies including 14303 cases and 15961 controls. PLoS One (2010) 0.94

α-Adducin Gly460Trp gene mutation and essential hypertension in a Chinese population: a meta-analysis including 10,960 subjects. PLoS One (2012) 0.93

Increased arterial smooth muscle Ca2+ signaling, vasoconstriction, and myogenic reactivity in Milan hypertensive rats. Am J Physiol Heart Circ Physiol (2011) 0.92

Replication of a GWAS signal in a Caucasian population implicates ADD3 in susceptibility to biliary atresia. Hum Genet (2013) 0.92

Genes involved in vasoconstriction and vasodilation system affect salt-sensitive hypertension. PLoS One (2011) 0.91

alpha- and beta-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathy. J Mol Med (Berl) (2009) 0.90

Alpha-adducin Gly460Trp polymorphism and essential hypertension in Korea. J Korean Med Sci (2004) 0.87

Analysis of renin-angiotensin aldosterone system gene polymorphisms in Malaysian essential hypertensive and type 2 diabetic subjects. Cardiovasc Diabetol (2009) 0.87

Virtual patients and sensitivity analysis of the Guyton model of blood pressure regulation: towards individualized models of whole-body physiology. PLoS Comput Biol (2012) 0.87

Genetics of stress response and stress-related disorders. Dialogues Clin Neurosci (2006) 0.86

γ-Adducin stimulates the thiazide-sensitive NaCl cotransporter. J Am Soc Nephrol (2010) 0.86

Hypertension pharmacogenomics: in search of personalized treatment approaches. Nat Rev Nephrol (2015) 0.85

Exploring the intricate regulatory network controlling the thiazide-sensitive NaCl cotransporter (NCC). Pflugers Arch (2011) 0.84

Gly460Trp polymorphism of the ADD1 gene and essential hypertension in an Indian population: A meta-analysis on hypertension risk. Indian J Hum Genet (2010) 0.84

Polymorphism of alpha-adducin and hypertension. Lancet (1997) 0.82

An α2-Na/K ATPase/α-adducin complex in astrocytes triggers non-cell autonomous neurodegeneration. Nat Neurosci (2014) 0.82

Impaired myogenic response of the afferent arteriole contributes to the increased susceptibility to renal disease in Milan normotensive rats. Physiol Rep (2017) 0.81

Genetics of hypertension: discoveries from the bench to human populations. Am J Physiol Renal Physiol (2013) 0.80

Hypertension genes and retinal vascular calibre: the Cardiovascular Health Study. J Hum Hypertens (2009) 0.80

Salt controls endothelial and vascular phenotype. Pflugers Arch (2014) 0.80

Interactions between the adducin 2 gene and antihypertensive drug therapies in determining blood pressure in people with hypertension. BMC Med Genet (2007) 0.79

Hydrochlorothiazide efficacy and polymorphisms in ACE, ADD1 and GNB3 in healthy, male volunteers. Eur J Clin Pharmacol (2006) 0.77

Do ACE (rs4646994) and αADDUCIN (rs4961) gene polymorphisms predict the recurrence of hypertensive intracerebral hemorrhage? Neurol Sci (2011) 0.76

Genetics of resistant hypertension: a novel pharmacogenomics phenotype. Curr Hypertens Rep (2015) 0.76

Polymorphisms in the GNB3 and ADD1 genes and blood pressure in a Chinese population. Hum Genet (2010) 0.76

Genome-wide linkage and positional association study of blood pressure response to dietary sodium intervention: the GenSalt Study. Am J Epidemiol (2012) 0.76

Pharmacogenetics of cardiovascular drug therapy. Clin Cases Miner Bone Metab (2009) 0.75

The Renin-Angiotensin System in the Development of Salt-Sensitive Hypertension in Animal Models and Humans. Pharmaceuticals (Basel) (2010) 0.75

Private genes, public health. Lancet (1997) 0.75

Adducin 1 (alpha) Gly460Trp variant is associated with left ventricular geometry in Caucasians and African Americans: The HyperGEN Study. Int J Mol Epidemiol Genet (2010) 0.75

Association of alpha-ADD1 Gene and Hypertension Risk: A Meta-Analysis. Med Sci Monit (2015) 0.75

Potential role of gene-environment interactions in ion transport mechanisms in the etiology of renal cell cancer. Sci Rep (2016) 0.75

The confounding effect of cryptic relatedness for environmental risks of systolic blood pressure on cohort studies. Mol Genet Genomic Med (2013) 0.75

Association between polymorphisms of alpha-adducin gene and essential hypertension in Chinese population. Biomed Res Int (2012) 0.75

Exome analysis reveals differentially mutated gene signatures of stage, grade and subtype in breast cancers. PLoS One (2015) 0.75

Identification of adducin-binding residues on the cytoplasmic domain of erythrocyte membrane protein, band 3. Biochem J (2016) 0.75

Articles by these authors

Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. Diabetes (2001) 9.67

Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J Exp Med (1998) 8.56

Paracellin-1, a renal tight junction protein required for paracellular Mg2+ resorption. Science (1999) 6.04

Association of nonalcoholic fatty liver disease with insulin resistance. Am J Med (1999) 5.65

A common molecular basis for three inherited kidney stone diseases. Nature (1996) 4.26

Metformin in non-alcoholic steatohepatitis. Lancet (2001) 3.63

Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes. Mol Psychiatry (2009) 3.56

Charcot-Marie-Tooth type 4B is caused by mutations in the gene encoding myotubularin-related protein-2. Nat Genet (2000) 2.96

A novel bipartite splicing enhancer modulates the differential processing of the human fibronectin EDA exon. Nucleic Acids Res (1994) 2.80

Determinants of adherence to osteoporosis treatment in clinical practice. Osteoporos Int (2006) 2.79

Factors associated with poor health-related quality of life of patients with cirrhosis. Gastroenterology (2001) 2.74

Differential regulation of chemokine receptors during dendritic cell maturation: a model for their trafficking properties. J Immunol (1998) 2.70

A multicenter cross sectional study on bone mineral density in rheumatoid arthritis. Italian Study Group on Bone Mass in Rheumatoid Arthritis. J Rheumatol (2000) 2.47

Identification of native protein folds amongst a large number of incorrect models. The calculation of low energy conformations from potentials of mean force. J Mol Biol (1990) 2.47

Conserved clusters of functionally related genes in two bacterial genomes. J Mol Evol (1997) 2.39

Mapping, cloning and genetic characterization of the region containing the Wilson disease gene. Nat Genet (1993) 2.29

Serum autoantibodies in chronic hepatitis C: comparison with autoimmune hepatitis and impact on the disease profile. Hepatology (1997) 2.21

Effect of the HMG-CoA reductase inhibitors on blood pressure in patients with essential hypertension and primary hypercholesterolemia. Hypertension (1999) 2.20

Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses. J Clin Invest (2001) 2.10

Uncoupling of inflammatory chemokine receptors by IL-10: generation of functional decoys. Nat Immunol (2000) 2.01

Induction of natural killer cell migration by monocyte chemotactic protein-1, -2 and -3. Eur J Immunol (1994) 2.01

R990G polymorphism of calcium-sensing receptor does produce a gain-of-function and predispose to primary hypercalciuria. Kidney Int (2007) 2.01

Pravastatin reduces carotid intima-media thickness progression in an asymptomatic hypercholesterolemic mediterranean population: the Carotid Atherosclerosis Italian Ultrasound Study. Am J Med (1996) 1.99

Related polypeptides are encoded by Drosophila F elements, I factors, and mammalian L1 sequences. Proc Natl Acad Sci U S A (1987) 1.85

Hypertension-associated point mutations in the adducin alpha and beta subunits affect actin cytoskeleton and ion transport. J Clin Invest (1996) 1.83

Endogenous ouabain, sodium balance and blood pressure: a review and a hypothesis. J Hypertens (1996) 1.83

A gene for Hirschsprung disease maps to the proximal long arm of chromosome 10. Nat Genet (1993) 1.79

Efficacy and safety of strontium ranelate in the treatment of osteoporosis in men. J Clin Endocrinol Metab (2013) 1.77

Strontium absorption and excretion in normocalciuric subjects: relation to calcium metabolism. Clin Chem (1998) 1.76

Exploring the Mycoplasma capricolum genome: a minimal cell reveals its physiology. Mol Microbiol (1995) 1.74

The nicotinic receptor beta 2 subunit is mutant in nocturnal frontal lobe epilepsy. Nat Genet (2000) 1.73

The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy. Cell Death Differ (2010) 1.63

Challenging times for bioinformatics. Nature (1995) 1.63

Safety of sperm washing and ART outcome in 741 HIV-1-serodiscordant couples. Hum Reprod (2006) 1.60

Consensus statement on the use of breastfeeding as a family planning method. Contraception (1989) 1.59

Cardiovascular outcomes after kidney-pancreas and kidney-alone transplantation. Kidney Int (2001) 1.58

Efficacy of a surveillance program for early detection of hepatocellular carcinoma. Cancer (1996) 1.57

Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56

Indwelling ureteral stents and sexual health: a prospective, multivariate analysis. J Urol (2007) 1.55

Chemokine receptor expression and function in CD4+ T lymphocytes with regulatory activity. J Immunol (2001) 1.55

Influence of age and parity on the development of the human breast. Breast Cancer Res Treat (1992) 1.54

Phenotypic intrafamilial heterogeneity in cystic fibrosis. Clin Genet (1993) 1.53

Elective segmental ureterectomy for transitional cell carcinoma of the ureter: long-term follow-up in a series of 73 patients. BJU Int (2012) 1.51

EUCLID: automatic classification of proteins in functional classes by their database annotations. Bioinformatics (1998) 1.49

Treatment of an aneurysm of the coeliac axis by transluminal steel wire occlusion. Eur J Vasc Endovasc Surg (1997) 1.48

Association of T-786C eNOS gene polymorphism with increased susceptibility to acute chest syndrome in females with sickle cell disease. Br J Haematol (2004) 1.48

Brain kinins are responsible for the pressor effect of intracerebroventricular captopril in spontaneously hypertensive rats. Hypertension (1990) 1.48

From endothelial dysfunction to atherosclerosis. Autoimmun Rev (2010) 1.47

Blood pressure changes produced by kidney cross-transplantation between spontaneously hypertensive rats and normotensive rats. Clin Sci Mol Med (1974) 1.47

CSF T-cell subsets in multiple sclerosis: relationship to cerebrospinal fluid myelin basic protein and clinical activity. J Neurol (1989) 1.46

Ventilation with positive end-expiratory pressure reduces extravascular lung water and increases lymphatic flow in hydrostatic pulmonary edema. Crit Care Med (1996) 1.46

Noninvasive management of obstructing ureteral stones using electromagnetic extracorporeal shock wave lithotripsy. Surg Endosc (2008) 1.46

A new locus for autosomal dominant nocturnal frontal lobe epilepsy maps to chromosome 1. Neurology (2000) 1.45

Physiological carotid body denervation during aging. Adv Exp Med Biol (2009) 1.45

Recombinations between IRP and cystic fibrosis. Am J Hum Genet (1988) 1.44

Mitochondrial myopathy, parkinsonism, and multiple mtDNA deletions in a Sephardic Jewish family. Neurology (2001) 1.43

Molecular analysis of uromodulin and SAH genes, positional candidates for autosomal dominant medullary cystic kidney disease linked to 16p12. J Nephrol (2001) 1.43

Acute respiratory distress syndrome among trauma patients: trends in ICU mortality, risk factors, complications and resource utilization. Intensive Care Med (2001) 1.42

The viral chemokine macrophage inflammatory protein-II is a selective Th2 chemoattractant. Blood (1998) 1.42

Incidence in Italy, genetic heterogeneity, and segregation analysis of cystic fibrosis. Am J Hum Genet (1985) 1.41

[Granulocytapheresis in inflammatory bowel disease. Efficacy of an induction plus maintenance sessions protocol at 32 weeks]. Rev Esp Enferm Dig (2007) 1.39

Computational comparisons of model genomes. Trends Biotechnol (1996) 1.38

Mapping a gene for familial situs abnormalities to human chromosome Xq24-q27.1. Nat Genet (1993) 1.37

Evidence that the penetrance of mutations at the RP11 locus causing dominant retinitis pigmentosa is influenced by a gene linked to the homologous RP11 allele. Am J Hum Genet (1997) 1.34

Towards a diagnostic and therapeutic consensus in male osteoporosis. Osteoporos Int (2011) 1.33

Genetic analysis in Italian families with inflammatory bowel disease supports linkage to the IBD1 locus--a GISC study. Eur J Hum Genet (1999) 1.32

Human tenascin: primary structure, pre-mRNA splicing patterns and localization of the epitopes recognized by two monoclonal antibodies. Nucleic Acids Res (1991) 1.31

Effects of three candidate genes on prevalence and incidence of hypertension in a Caucasian population. J Hypertens (2001) 1.30

A common mutation in Sardinian autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients. Hum Genet (1998) 1.30

A second genetic locus for autosomal dominant polycystic kidney disease. Lancet (1988) 1.29

Modulation of IgE reactivity of allergens by site-directed mutagenesis: potential use of hypoallergenic variants for immunotherapy. FASEB J (1998) 1.28

Left ventricular mass, stroke volume, and ouabain-like factor in essential hypertension. Hypertension (1999) 1.28

Tissue-specific splicing pattern of fibronectin messenger RNA precursor during development and aging in rat. J Cell Biol (1991) 1.27

Why is the cystic fibrosis gene so frequent? Hum Genet (1989) 1.26

Vitamin D status and response to treatment in post-menopausal osteoporosis. Osteoporos Int (2008) 1.26

A new locus for autosomal recessive hereditary spastic paraplegia maps to chromosome 16q24.3. Am J Hum Genet (1998) 1.25

The locus for a novel syndromic form of neuronal intestinal pseudoobstruction maps to Xq28. Am J Hum Genet (1996) 1.24

Measurement of the electron charge asymmetry in inclusive W production in pp collisions at sqrt[s]=7  TeV. Phys Rev Lett (2012) 1.23

Autosomal recessive rolandic epilepsy with paroxysmal exercise-induced dystonia and writer's cramp: delineation of the syndrome and gene mapping to chromosome 16p12-11.2. Ann Neurol (1999) 1.23

Tumor seeding in urological laparoscopy: an international survey. J Urol (2004) 1.21

Novel molecular variants of the Na-Cl cotransporter gene are responsible for Gitelman syndrome. Am J Hum Genet (1996) 1.21

Prorenin in high concentrations in human ovarian follicular fluid. Science (1986) 1.20

Search for new physics in the multijet and missing transverse momentum final state in proton-proton collisions at √s = 7 TeV. Phys Rev Lett (2012) 1.19

Azimuthal anisotropy of charged particles at high transverse momenta in Pb-Pb collisions at sqrt[s(NN)] = 2.76  TeV. Phys Rev Lett (2012) 1.19

Bone fragility in men--where are we? Osteoporos Int (2006) 1.19

Antibodies of the anti-Yo and anti-Ri type in the absence of paraneoplastic neurological syndromes: a long-term survey of ovarian cancer patients. J Neurol (1997) 1.18

GeneQuiz: a workbench for sequence analysis. Proc Int Conf Intell Syst Mol Biol (1994) 1.17

Two point mutations within the adducin genes are involved in blood pressure variation. Proc Natl Acad Sci U S A (1994) 1.17

Morphine tissue levels and reduction of gastrointestinal transit in rats. Correlation supports primary action site in the gut. Gastroenterology (1983) 1.16

The 2A proteinase of human rhinovirus is a zinc containing enzyme. Virology (1994) 1.16

Inhibition of gastrointestinal transit by morphine in rats results primarily from direct drug action on gut opioid sites. J Pharmacol Exp Ther (1986) 1.15

Localization of a gene responsible for autosomal recessive demyelinating neuropathy with focally folded myelin sheaths to chromosome 11q23 by homozygosity mapping and haplotype sharing. Hum Mol Genet (1996) 1.13

A knotted multi-length ureteral stent: a rare complication. Urol Res (2004) 1.13