Published in Mol Biol Cell on May 01, 1997
Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature. Cell Stress Chaperones (2000) 1.91
Discrimination between NL1- and NL2-mediated nuclear localization of the glucocorticoid receptor. Mol Cell Biol (1999) 1.66
Importin 7 and importin alpha/importin beta are nuclear import receptors for the glucocorticoid receptor. Mol Biol Cell (2004) 1.59
Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice. J Clin Invest (2009) 1.51
Farnesylation of Ydj1 is required for in vivo interaction with Hsp90 client proteins. Mol Biol Cell (2008) 1.17
Glucocorticoid receptor homodimers and glucocorticoid-mineralocorticoid receptor heterodimers form in the cytoplasm through alternative dimerization interfaces. Mol Cell Biol (2001) 0.99
Paeoniflorin, a novel heat shock protein-inducing compound. Cell Stress Chaperones (2004) 0.96
The nuclear receptor superfamily: the second decade. Cell (1995) 24.99
Nuclear targeting sequences--a consensus? Trends Biochem Sci (1991) 16.65
Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature (1984) 10.52
Speculations on the functions of the major heat shock and glucose-regulated proteins. Cell (1986) 10.35
The GTP-binding protein Ran/TC4 is required for protein import into the nucleus. Nature (1993) 7.80
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA. Nature (1991) 7.46
A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell (1992) 7.11
Common principles of protein translocation across membranes. Science (1996) 7.00
Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins. Cell (1995) 6.97
Transcription factor interactions: selectors of positive or negative regulation from a single DNA element. Science (1990) 6.72
Isolation of a protein that is essential for the first step of nuclear protein import. Cell (1994) 6.63
Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor. J Cell Biol (1993) 6.47
Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor. EMBO J (1987) 5.76
Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones. Nature (1994) 4.75
The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex. Cell (1995) 4.55
Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells. J Biol Chem (1984) 4.20
Distinct functions for the two importin subunits in nuclear protein import. Nature (1995) 4.16
Pores for thought: nuclear pore complex proteins. Trends Cell Biol (1994) 4.08
Hip, a novel cochaperone involved in the eukaryotic Hsc70/Hsp40 reaction cycle. Cell (1995) 3.99
Structure and function of the nuclear pore complex. Annu Rev Cell Biol (1992) 3.95
Role of the protein chaperone YDJ1 in establishing Hsp90-mediated signal transduction pathways. Science (1995) 3.91
DnaJ-like proteins: molecular chaperones and specific regulators of Hsp70. Trends Biochem Sci (1994) 3.65
Previously identified protein of uncertain function is karyopherin alpha and together with karyopherin beta docks import substrate at nuclear pore complexes. Proc Natl Acad Sci U S A (1995) 3.52
Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B. Genes Dev (1992) 3.47
Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement. Nature (1987) 3.42
Structural determinants of nuclear receptor assembly on DNA direct repeats. Nature (1995) 3.32
Hsp70 accelerates the recovery of nucleolar morphology after heat shock. EMBO J (1984) 3.24
Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex. Nature (1991) 3.21
Identification of specific binding proteins for a nuclear location sequence. Nature (1989) 3.11
The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements. Cell (1993) 2.95
The transport of proteins into the nucleus requires the 70-kilodalton heat shock protein or its cytosolic cognate. Mol Cell Biol (1992) 2.85
Arginine/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing. Cell (1991) 2.69
Steroid receptors and their associated proteins. Mol Endocrinol (1993) 2.62
Regulation of Hsp70 function by a eukaryotic DnaJ homolog. J Biol Chem (1992) 2.46
The role of heat shock proteins in regulating the function, folding, and trafficking of the glucocorticoid receptor. J Biol Chem (1993) 2.42
A ligand-dependent bipartite nuclear targeting signal in the human androgen receptor. Requirement for the DNA-binding domain and modulation by NH2-terminal and carboxyl-terminal sequences. J Biol Chem (1994) 2.35
In vivo nuclear transport kinetics in Saccharomyces cerevisiae: a role for heat shock protein 70 during targeting and translocation. J Cell Biol (1996) 2.33
A zinc finger-like domain of the molecular chaperone DnaJ is involved in binding to denatured protein substrates. EMBO J (1996) 2.33
An amino acid sequence motif sufficient for subnuclear localization of an arginine/serine-rich splicing factor. Proc Natl Acad Sci U S A (1995) 1.92
Yeast proteins that recognize nuclear localization sequences. J Cell Biol (1989) 1.92
Cooperation of proto-signals for nuclear accumulation of estrogen and progesterone receptors. EMBO J (1992) 1.88
DNA binding-induced conformational change of the yeast transcriptional activator PRTF. Cell (1990) 1.78
Hold 'em and fold 'em: chaperones and signal transduction. Science (1995) 1.74
Antibodies against 70-kD heat shock cognate protein inhibit mediated nuclear import of karyophilic proteins. J Cell Biol (1992) 1.74
Multiple pathways in nuclear transport: the import of U2 snRNP occurs by a novel kinetic pathway. J Cell Biol (1991) 1.71
Modulation of transcription factor Ets-1 DNA binding: DNA-induced unfolding of an alpha helix. Science (1995) 1.71
Mechanisms of nuclear localization of the progesterone receptor: evidence for interaction between monomers. Cell (1989) 1.60
Nuclear import of the human androgen receptor. Biochem J (1993) 1.58
Evidence for an anti-parallel orientation of the ligand-activated human androgen receptor dimer. J Biol Chem (1995) 1.54
Characterization of a monoclonal antibody to the rat liver glucocorticoid receptor. Endocrinology (1984) 1.50
Mechanisms of protein import across the mitochondrial outer membrane. Trends Cell Biol (1996) 1.49
Cooperation of the molecular chaperone Ydj1 with specific Hsp70 homologs to suppress protein aggregation. FEBS Lett (1995) 1.48
Signal transduction by steroid hormones: nuclear localization is differentially regulated in estrogen and glucocorticoid receptors. Cell Regul (1990) 1.46
Intracellular receptors use a common mechanism to interpret signaling information at response elements. Genes Dev (1996) 1.46
Anatomy of the steroid receptor zinc finger region. Endocr Rev (1992) 1.44
A region in the steroid binding domain determines formation of the non-DNA-binding, 9 S glucocorticoid receptor complex. J Biol Chem (1988) 1.41
Novel antipeptide antibodies to the human glucocorticoid receptor: recognition of multiple receptor forms in vitro and distinct localization of cytoplasmic and nuclear receptors. Mol Endocrinol (1990) 1.40
Hormone-dependent transactivation by the human androgen receptor is regulated by a dnaJ protein. J Biol Chem (1995) 1.39
Differential roles of heat shock protein 70 in the in vitro nuclear import of glucocorticoid receptor and simian virus 40 large tumor antigen. Mol Cell Biol (1994) 1.35
Differential distribution of the adenovirus E1A proteins and colocalization of E1A with the 70-kilodalton cellular heat shock protein in infected cells. J Virol (1988) 1.33
Localization of the glucocorticoid receptor in discrete clusters in the cell nucleus. J Cell Sci (1995) 1.26
Ligand-dependent, transcriptionally productive association of the amino- and carboxyl-terminal regions of a steroid hormone nuclear receptor. Proc Natl Acad Sci U S A (1995) 1.23
Localization of the 90-kDa heat shock protein-binding site within the hormone-binding domain of the glucocorticoid receptor by peptide competition. J Biol Chem (1991) 1.19
Effects of okadaic acid, a protein phosphatase inhibitor, on glucocorticoid receptor-mediated enhancement. Mol Endocrinol (1992) 1.16
How ATP drives proteins across membranes. Science (1994) 1.15
Mapping the HSP90 binding region of the glucocorticoid receptor. J Biol Chem (1990) 1.15
v-mos oncoproteins affect the nuclear retention and reutilization of glucocorticoid receptors. Mol Endocrinol (1989) 1.14
Conformational alteration of Oct-1 upon DNA binding dictates selectivity in differential interactions with related transcriptional coactivators. Mol Cell Biol (1996) 1.12
ATP-dependent release of glucocorticoid receptors from the nuclear matrix. Mol Cell Biol (1996) 1.04
Nuclear colocalization of cellular and viral myc proteins with HSP70 in myc-overexpressing cells. J Virol (1991) 1.03
Cloning of a unique human homologue of the Escherichia coli DNAJ heat shock protein. Biochim Biophys Acta (1993) 0.98
Assessment of glucocorticoid receptor-heat shock protein 90 interactions in vivo during nucleocytoplasmic trafficking. Mol Endocrinol (1996) 0.97
Hormonal regulation of the nuclear localization signals of the human glucocorticosteroid receptor. Exp Cell Res (1992) 0.94
Human cDNA encoding DnaJ protein homologue. Biochim Biophys Acta (1993) 0.92
Demonstration by confocal microscopy that unliganded overexpressed glucocorticoid receptors are distributed in a nonrandom manner throughout all planes of the nucleus. Mol Endocrinol (1991) 0.92
Post-translational protein import and folding. Curr Opin Cell Biol (1994) 0.90
Nuclear colocalization of c-myc protein and hsp70 in cells transfected with human wild-type and mutant c-myc genes. Exp Cell Res (1992) 0.87
Region-specific antiglucocorticoid receptor antibodies selectively recognize the activated form of the ligand-occupied receptor and inhibit the binding of activated complexes to deoxyribonucleic acid. Mol Endocrinol (1989) 0.82
Reconstitution of ligand-mediated glucocorticoid receptor activity by trans-acting functional domains. Mol Endocrinol (1993) 0.78
Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1. Nat Genet (1998) 4.27
Growth of cultured human epidermal cells into multiple epithelia suitable for grafting. Proc Natl Acad Sci U S A (1979) 3.79
Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsiveness. J Immunol (1995) 3.69
Results at 1 year of outpatient multidisciplinary pulmonary rehabilitation: a randomised controlled trial. Lancet (2000) 3.68
Glucocorticoids selectively inhibit the transcription of the interleukin 1 beta gene and decrease the stability of interleukin 1 beta mRNA. Proc Natl Acad Sci U S A (1988) 3.34
Seronegative Lyme disease. Dissociation of specific T- and B-lymphocyte responses to Borrelia burgdorferi. N Engl J Med (1988) 3.26
Stereochemical criteria for polypeptide and protein chain conformations. II. Allowed conformations for a pair of peptide units. Biophys J (1965) 3.25
A comparison of clozapine and haloperidol in hospitalized patients with refractory schizophrenia. Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. N Engl J Med (1997) 3.12
Intestinal fluid and electrolyte transport in human cholera. J Clin Invest (1970) 3.09
Maintenance of genomic imprinting at the Arabidopsis medea locus requires zygotic DDM1 activity. Genes Dev (1999) 2.97
Formation of glutamine from [13n]ammonia, [13n]dinitrogen, and [14C]glutamate by heterocysts isolated from Anabaena cylindrica. J Bacteriol (1977) 2.88
Early restaging positron emission tomography with ( 18)F-fluorodeoxyglucose predicts outcome in patients with aggressive non-Hodgkin's lymphoma. Ann Oncol (2002) 2.86
Pathway of nitrogen metabolism after fixation of 13N-labeled nitrogen gas by the cyanobacterium, Anabaena cylindrica. J Biol Chem (1976) 2.85
High interlaboratory reproducibility of DNA sequence-based typing of bacteria in a multicenter study. J Clin Microbiol (2006) 2.80
The pathways of assimilation of 13NH4+ by the cyanobacterium, Anabaena cylindrica. J Biol Chem (1977) 2.77
A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission. Nature (1997) 2.74
Mitochondrial and peroxisomal fatty acid oxidation in liver homogenates and isolated hepatocytes from control and clofibrate-treated rats. J Biol Chem (1979) 2.66
Initial organic products of assimilation of [N]ammonium and [N]nitrate by tobacco cells cultured on different sources of nitrogen. Plant Physiol (1978) 2.54
Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families. Nat Genet (1996) 2.48
Interim report on pandemic H1N1 influenza virus infections in South Africa, April to October 2009: epidemiology and factors associated with fatal cases. Euro Surveill (2009) 2.47
Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures. J Biol Chem (2000) 2.43
Cis and trans mRNA splicing in C. elegans. Trends Genet (1988) 2.34
Levamisole: a dangerous new cocaine adulterant. Clin Pharmacol Ther (2010) 2.17
An updatable holographic three-dimensional display. Nature (2008) 2.14
Legume-Rhizobium interactions: cowpea root exudate elicits faster nodulation response by Rhizobium species. Appl Environ Microbiol (1982) 2.14
Accuracy of intraoperative frozen-section analysis of axillary nodes. Edinburgh Breast Unit team. Br J Surg (1999) 2.10
Predicting splice variant from DNA chip expression data. Genome Res (2001) 2.09
Changing pattern of the detection of locoregional relapse in breast cancer: the Edinburgh experience. Br J Cancer (2007) 2.07
Inheritance and expression of chimeric genes in the progeny of transgenic maize plants. Biotechnology (N Y) (1990) 2.05
Marginal zone B-cell lymphomas of different sites share similar cytogenetic and morphologic features. Blood (1996) 2.02
[Some reflextions apropos of 45 cases of malarial comas confirmed parasitologically in children under 6 years old]. Med Trop (Mars) (1969) 2.01
Absence of the pigments of photosystem II of photosynthesis in heterocysts of a blue-green alga. Nature (1970) 2.00
Prevalence of coronary heart disease in the rural population of Thiruvananthapuram district, Kerala, India. Int J Cardiol (1993) 2.00
Stereochemical modeling of disulfide bridges. Criteria for introduction into proteins by site-directed mutagenesis. Protein Eng (1989) 1.98
Conformations of disulfide bridges in proteins. Int J Pept Protein Res (1990) 1.90
Insertion of part of an intron into the 5' untranslated region of a Caenorhabditis elegans gene converts it into a trans-spliced gene. Mol Cell Biol (1991) 1.85
Human cDNAs encoding homologs of the small p34Cdc28/Cdc2-associated protein of Saccharomyces cerevisiae and Schizosaccharomyces pombe. Genes Dev (1990) 1.83
[Clinical and parasitic latency in filariasis due to Loa loa and Onchocerca volvulus]. Bull Soc Pathol Exot Filiales (1970) 1.76
Alternatives to randomisation in the evaluation of public-health interventions: statistical analysis and causal inference. J Epidemiol Community Health (2009) 1.74
Follicular adenoma with papillary architecture: a lesion mimicking papillary thyroid carcinoma. Histopathology (2001) 1.72
Magnetic resonance imaging in the diagnosis of disc degeneration: correlation with discography. Spine (Phila Pa 1976) (1987) 1.67
Treatment with subantimicrobial dose doxycycline improves the efficacy of scaling and root planing in patients with adult periodontitis. J Periodontol (2000) 1.65
Holographic three-dimensional telepresence using large-area photorefractive polymer. Nature (2010) 1.64
Standard chemotherapy with or without high-dose chemotherapy for aggressive non-Hodgkin's lymphoma: randomized phase III EORTC study. J Natl Cancer Inst (2001) 1.63
Phenylketonuria in adulthood: a collaborative study. J Inherit Metab Dis (2002) 1.61
Initial experience with the disarticulated (one-half) Palmaz-Schatz stent: a technical report. Cathet Cardiovasc Diagn (1992) 1.61
Flagellin polymerisation control by a cytosolic export chaperone. J Mol Biol (2001) 1.61
Controlled comparison of tetracycline and furazolidone in cholera. Br Med J (1968) 1.59
Opioid activation of toll-like receptor 4 contributes to drug reinforcement. J Neurosci (2012) 1.55
Trends in retail prescription expenditures. Health Aff (Millwood) (1990) 1.52
A multicentre study of capecitabine, oxaliplatin plus bevacizumab as perioperative treatment of patients with poor-risk colorectal liver-only metastases not selected for upfront resection. Ann Oncol (2011) 1.51
Use of molecular assays in diagnosis and monitoring of cytomegalovirus disease following renal transplantation. J Clin Microbiol (1999) 1.50
Management of hepatitis A in a food handler at a London secondary school. Commun Dis Public Health (2003) 1.49
Child maltreatment, other trauma exposure, and posttraumatic symptomatology among children with oppositional defiant and attention deficit hyperactivity disorders. Child Maltreat (2000) 1.47
Aspirin intolerance--a review. Ann Allergy (1977) 1.47
Mitral valve disease and open heart surgery in osteogenesis imperfecta tarda. Br Heart J (1973) 1.46
Regulation of insulin/insulin-like growth factor-1 signaling by proteasome-mediated degradation of insulin receptor substrate-2. J Biol Chem (2001) 1.45
Reevaluation of total-lymphoid irradiation and cyclosporine therapy in the Syrian hamster-to-Lewis rat cardiac xenograft model. Transplantation (1990) 1.45
Substrate complexes and domain organization of the Salmonella flagellar export chaperones FlgN and FliT. Mol Microbiol (2001) 1.45
Racial differences in the incidence of gout. The role of hypertension. Arthritis Rheum (1995) 1.43
Structure of Plant Cell Walls : XXVI. The Walls of Suspension-Cultured Sycamore Cells Contain a Family of Rhamnogalacturonan-I-Like Pectic Polysaccharides. Plant Physiol (1989) 1.40
The initial organic products of fixation of 13N-labeled nitrogen gas by the blue-green alga Anabaena cylindrica. Biochem Biophys Res Commun (1975) 1.40
Experience with high frequency oscillation ventilation during the 2009 H1N1 influenza pandemic in Australia and New Zealand. Anaesth Intensive Care (2011) 1.40
Indapamide in the treatment of essential arterial hypertension in the elderly. Postgrad Med J (1981) 1.40
Pancreatic xanthomatous neuropathy associated with hyperlipidemia: a cause of abdominal pain mimicking chronic pancreatitis. Hum Pathol (1993) 1.39
Specific immune responses in Lyme borreliosis. Characterization of T cell and B cell responses to Borrelia burgdorferi. Ann N Y Acad Sci (1988) 1.39
Hyperprolactinemia in women--a series of 71 cases. J Assoc Physicians India (1993) 1.37
Differential roles of heat shock protein 70 in the in vitro nuclear import of glucocorticoid receptor and simian virus 40 large tumor antigen. Mol Cell Biol (1994) 1.35
MODIP revisited: re-evaluation and refinement of an automated procedure for modeling of disulfide bonds in proteins. Protein Eng (2003) 1.33
A genome scan for type 2 diabetes susceptibility loci in a genetically isolated population. Diabetes (2001) 1.31
Obesity and hypertension in a longitudinal study of black physicians: the Meharry Cohort Study. J Chronic Dis (1986) 1.30
Gout and risk for subsequent coronary heart disease. The Meharry-Hopkins Study. Arch Intern Med (1997) 1.30
Characterization of the MODY3 phenotype. Early-onset diabetes caused by an insulin secretion defect. J Clin Invest (1997) 1.30
HIV-related behaviours among voluntary blood donors in Hong Kong. AIDS Care (2002) 1.29
Risk behaviours of Hong Kong male residents travelling to mainland China: a potential bridge population for HIV infection. AIDS Care (2001) 1.26
Immunological monitoring of long-surviving renal transplant recipients. Surgery (1977) 1.25
The use of oral replacement solutions in the treatment of choleraand other severe diarrhoeal disorders. Bull World Health Organ (1970) 1.25
Interaction of the tau2 transcriptional activation domain of glucocorticoid receptor with a novel steroid receptor coactivator, Hic-5, which localizes to both focal adhesions and the nuclear matrix. Mol Biol Cell (2000) 1.25
A procedure for the prediction of temperature-sensitive mutants of a globular protein based solely on the amino acid sequence. Proc Natl Acad Sci U S A (1996) 1.25
The prognostic significance in HIV infection of immune activation represented by cell surface antigen and plasma activation marker changes. Clin Immunol (1999) 1.25
Chemical compositions of elastins isolated from aortas and pulmonary tissues of humans of different ages. Biochem J (1972) 1.24
Structure of Leishmania mexicana lipophosphoglycan. J Biol Chem (1992) 1.24
Domestic violence: a comparative survey of levels of detection, knowledge, and attitudes in healthcare workers. Public Health (2001) 1.23
Beta-hairpins in proteins revisited: lessons for de novo design. Protein Eng (1997) 1.22
Relationship between Sodium Influx and Salt Tolerance of Nitrogen-Fixing Cyanobacteria. Appl Environ Microbiol (1987) 1.22
Pharmacokinetics of chlormethiazole in humans. Eur J Clin Pharmacol (1975) 1.21
Incorporation of labelled lysine into the desmosine cross-bridges in elastin. Nature (1966) 1.21
Affective and physiological responses to racism: the roles of afrocentrism and mode of presentation. Ethn Dis (1996) 1.21
Phosphate/hexose 6-phosphate antiport in Streptococcus lactis. J Bacteriol (1984) 1.21
Chromatin recycling of glucocorticoid receptors: implications for multiple roles of heat shock protein 90. Mol Endocrinol (1999) 1.20
Promotion of incompatible allograft acceptance in rhesus monkeys given posttransplant antithymocyte globulin and donor bone marrow. I. In vivo parameters and immunohistologic evidence suggesting microchimerism. Transplantation (1987) 1.20
Admitting by computer. Hosp Adm Can (1978) 1.20
Characteristic pattern of chromosomal gains and losses in marginal zone B cell lymphoma detected by comparative genomic hybridization. Leukemia (1997) 1.19
Calicheamicins, a novel family of antitumor antibiotics: taxonomy, fermentation and biological properties. J Antibiot (Tokyo) (1989) 1.19
Action of metformin on glucose transport and glucose transporter GLUT1 and GLUT4 in heart muscle cells from healthy and diabetic rats. Endocrinology (1995) 1.18
Viral replication is required for induction of ocular immunopathology by herpes simplex virus. J Virol (1996) 1.17
Psychological sequelae following the Gulf War. Factors associated with subsequent morbidity and the effectiveness of psychological debriefing. Br J Psychiatry (1994) 1.17
Hypothermia during reperfusion after asphyxial cardiac arrest improves functional recovery and selectively alters stress-induced protein expression. J Cereb Blood Flow Metab (2000) 1.17
Stereochemical punctuation marks in protein structures: glycine and proline containing helix stop signals. J Mol Biol (1998) 1.17