Published in Exp Neurol on May 01, 1997
Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Müller cells temporarily rescues injured retinal ganglion cells. Proc Natl Acad Sci U S A (1998) 1.60
Neurotrophin roles in retinal ganglion cell survival: lessons from rat glaucoma models. Exp Eye Res (2009) 1.08
Combined application of BDNF to the eye and brain enhances ganglion cell survival and function in the cat after optic nerve injury. Invest Ophthalmol Vis Sci (2009) 1.07
Ethanol-BDNF interactions: still more questions than answers. Pharmacol Ther (2008) 1.06
Is BDNF sufficient for information transfer between microglia and dorsal horn neurons during the onset of central sensitization? Mol Pain (2010) 0.92
TrkB gene transfer does not alter hippocampal neuronal loss and cognitive deficits following traumatic brain injury in mice. Restor Neurol Neurosci (2008) 0.85
BDNF treatment and extended recovery from optic nerve trauma in the cat. Invest Ophthalmol Vis Sci (2013) 0.84
Contrasting hippocampal and amygdalar expression of genes related to neural plasticity during escape from social aggression. Physiol Behav (2012) 0.84
Targeted delivery of brain-derived neurotrophic factor for the treatment of blindness and deafness. Int J Nanomedicine (2015) 0.84
Brain-derived neurotrophic factor and exercise in fibromyalgia syndrome patients: a mini review. Rheumatol Int (2011) 0.83
The behavioral and biochemical effects of BDNF containing polymers implanted in the hippocampus of rats. Brain Res (2010) 0.81
Overexpression of BDNF increases excitability of the lumbar spinal network and leads to robust early locomotor recovery in completely spinalized rats. PLoS One (2014) 0.81
Neurochemical properties of BDNF-containing neurons projecting to rostral ventromedial medulla in the ventrolateral periaqueductal gray. Front Neural Circuits (2014) 0.78
Human Pluripotent Stem Cell-Derived Retinal Ganglion Cells: Applications for the Study and Treatment of Optic Neuropathies. Curr Ophthalmol Rep (2015) 0.78
Intranasal Delivery of Recombinant AAV Containing BDNF Fused with HA2TAT: a Potential Promising Therapy Strategy for Major Depressive Disorder. Sci Rep (2016) 0.77
The BDNF Val66Met polymorphism is associated with the functional connectivity dynamics of pain modulatory systems in primary dysmenorrhea. Sci Rep (2016) 0.76
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science (1997) 15.48
Vascular-specific growth factors and blood vessel formation. Nature (2000) 14.42
Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science (1999) 9.18
Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat Med (2000) 5.58
Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting. Proc Natl Acad Sci U S A (2007) 4.27
Anterograde transport of brain-derived neurotrophic factor and its role in the brain. Nature (1997) 4.01
Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology. Peptides (1986) 3.51
New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF. Oncogene (1999) 3.45
Infusion of brain-derived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamus. J Neurosci (2001) 3.23
NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression. Neuron (1990) 3.12
VEGF-initiated blood-retinal barrier breakdown in early diabetes. Invest Ophthalmol Vis Sci (2001) 3.08
Neurotrophin-3: a neurotrophic factor related to NGF and BDNF. Science (1990) 2.91
Acute interstitial nephritis due to drugs: Review of the literature with a report of nine cases. Ann Intern Med (1980) 2.78
A BDNF autocrine loop in adult sensory neurons prevents cell death. Nature (1995) 2.75
Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes. J Neurosci (1991) 2.73
BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra. Nature (1991) 2.70
Antidepressant-like effect of brain-derived neurotrophic factor (BDNF). Pharmacol Biochem Behav (1997) 2.67
Sodium ferric gluconate complex in sucrose is safe and effective in hemodialysis patients: North American Clinical Trial. Am J Kidney Dis (1999) 2.24
The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons. Neuron (1992) 2.11
Arrest of motor neuron disease in wobbler mice cotreated with CNTF and BDNF. Science (1994) 1.98
Factors affecting the prognosis in acute renal failure. A survey of 251 cases. Q J Med (1973) 1.91
Neurotrophic factors: from molecule to man. Trends Neurosci (1994) 1.88
Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4-phenylpyridinium ion toxicity: involvement of the glutathione system. J Neurochem (1992) 1.85
Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity. Proc Natl Acad Sci U S A (2001) 1.79
Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture. Neuron (1990) 1.77
Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity. Proc Natl Acad Sci U S A (1999) 1.73
BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration. J Neurosci (1997) 1.71
The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development. Neuron (1993) 1.67
Hyperalgesia, synovitis and multiple biomarkers of inflammation are suppressed by interleukin 1 inhibition in a novel animal model of gouty arthritis. Ann Rheum Dis (2009) 1.64
Vascular apoptosis and involution in gliomas precede neovascularization: a novel concept for glioma growth and angiogenesis. Lab Invest (2000) 1.62
Intraventricular administration of BDNF increases the number of newly generated neurons in the adult olfactory bulb. Mol Cell Neurosci (1998) 1.61
Preclinical characterization of selective phosphodiesterase 10A inhibitors: a new therapeutic approach to the treatment of schizophrenia. J Pharmacol Exp Ther (2008) 1.60
Placode and neural crest-derived sensory neurons are responsive at early developmental stages to brain-derived neurotrophic factor. Dev Biol (1985) 1.57
Discrete lesions reveal functional heterogeneity of suprachiasmatic structures in regulation of gonadotropin secretion in the female rat. Neuroendocrinology (1982) 1.55
Association of intradialytic blood pressure changes with hospitalization and mortality rates in prevalent ESRD patients. Kidney Int (2007) 1.54
Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain. J Neurosci (1995) 1.52
The effects of ciliary neurotrophic factor on motor dysfunction in wobbler mouse motor neuron disease. Ann Neurol (1994) 1.52
Prenatal glucocorticoid exposure leads to offspring hyperglycaemia in the rat: studies with the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone. Diabetologia (1996) 1.49
In situ expression of angiopoietins in astrocytomas identifies angiopoietin-2 as an early marker of tumor angiogenesis. Exp Neurol (1999) 1.47
BDNF and NT-3 rescue sensory but not motoneurones following axotomy in the neonate. Neuroreport (1994) 1.47
Ciliary neurotrophic factor and stress stimuli activate the Jak-STAT pathway in retinal neurons and glia. J Neurosci (2000) 1.45
Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex. Neuroscience (1999) 1.44
Molecular events implicated in brain tumor angiogenesis and invasion. Pediatr Neurosurg (2000) 1.43
Inhibition of 11-beta-hydroxysteroid dehydrogenase in pregnant rats and the programming of blood pressure in the offspring. Hypertension (1996) 1.37
Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression. Behav Neurosci (2001) 1.36
Degeneration of vestibular neurons in late embryogenesis of both heterozygous and homozygous BDNF null mutant mice. Development (1996) 1.36
Criteria for distinguishing normal from subnormal adrenocortical function using the Synacthen test. Postgrad Med J (1969) 1.35
The ciliary neurotrophic factor and its receptor, CNTFR alpha. Pharm Acta Helv (2000) 1.35
Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF. J Neurosci (1993) 1.30
Physiological characterization of Taxol-induced large-fiber sensory neuropathy in the rat. Ann Neurol (1998) 1.29
Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon. J Neurosci (1994) 1.28
Effects of discrete lesions of preoptic and suprachiasmatic structures in the female rat. Alterations in the feedback regulation of gonadotropin secretion. Neuroendocrinology (1980) 1.26
Brain-derived neurotrophic factor improves blood glucose control and alleviates fasting hyperglycemia in C57BLKS-Lepr(db)/lepr(db) mice. Diabetes (1999) 1.25
Ciliary neurotrophic factor improves diabetic parameters and hepatic steatosis and increases basal metabolic rate in db/db mice. Proc Natl Acad Sci U S A (2003) 1.24
Haemostatic changes during dialysis associated with thrombus formation on dialysis membranes. Br Med J (1972) 1.24
Vascular endothelial growth factor is up-regulated after status epilepticus and protects against seizure-induced neuronal loss in hippocampus. Neuroscience (2007) 1.23
New factor released by cultured glioma cells supporting survival and growth of sensory neurones. Nature (1978) 1.23
Brain-derived neurotrophic factor augments rotational behavior and nigrostriatal dopamine turnover in vivo. Proc Natl Acad Sci U S A (1992) 1.22
Retrograde axonal transport of LIF is increased by peripheral nerve injury: correlation with increased LIF expression in distal nerve. Neuron (1994) 1.22
Axotomy upregulates the anterograde transport and expression of brain-derived neurotrophic factor by sensory neurons. J Neurosci (1998) 1.20
Adult rat brain astrocytes support survival of both NGF-dependent and NGF-insensitive neurones. Nature (1979) 1.20
Carbenoxolone increases hepatic insulin sensitivity in man: a novel role for 11-oxosteroid reductase in enhancing glucocorticoid receptor activation. J Clin Endocrinol Metab (1995) 1.19
Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection. J Neurosci (1993) 1.19
Influence of neurotrophic factors on morphine- and cocaine-induced biochemical changes in the mesolimbic dopamine system. Neuroscience (1995) 1.19
Regulation of ciliary neurotrophic factor expression in myelin-related Schwann cells in vivo. Neuron (1992) 1.18
Differences in the chemical expression of rat primary afferent neurons which innervate skin, muscle or joint. Neuroscience (1989) 1.17
BDNF and NT-4/5 exert neurotrophic influences on injured adult spinal motor neurons. J Neurosci (1995) 1.16
Noradrenergic sympathetic innervation of the spleen: I. Nerve fibers associate with lymphocytes and macrophages in specific compartments of the splenic white pulp. J Neurosci Res (1987) 1.14
Trophic effect of ciliary neurotrophic factor on denervated skeletal muscle. Cell (1994) 1.14
Hippocampal mossy fiber sprouting induced by chronic electroconvulsive seizures. Neuroscience (1999) 1.14
Neurotrophin 4 is required for the survival of a subclass of hair follicle receptors. J Neurosci (1998) 1.13
BDNF increases monoaminergic activity in rat brain following intracerebroventricular or intraparenchymal administration. Brain Res (1996) 1.12
Identification of functional receptors for ciliary neurotrophic factor on neuronal cell lines and primary neurons. Neuron (1990) 1.11
Insulin and insulin-like growth factor I enhance regeneration in cultured adult rat sensory neurones. Brain Res (1993) 1.10
Retrograde axonal transport of ciliary neurotrophic factor is increased by peripheral nerve injury. Nature (1993) 1.09
Neurotrophic factor receptors and their signal transduction capabilities in rat astrocytes. Eur J Neurosci (1994) 1.09
Serotonin and pulmonary hypertension in human septic ARDS. Crit Care Med (1980) 1.08
The growth-associated protein GAP-43 appears in dorsal root ganglion cells and in the dorsal horn of the rat spinal cord following peripheral nerve injury. Neuroscience (1990) 1.07
Separate neurons in the paraventricular nucleus project to the median eminence and to the medulla or spinal cord. Brain Res (1980) 1.07
In situ hybridization of trkB and trkC receptor mRNA in rat forebrain and association with high-affinity binding of [125I]BDNF, [125I]NT-4/5 and [125I]NT-3. Eur J Neurosci (1994) 1.06
The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro. Eur J Neurosci (1995) 1.06
Comparison of measured and predicted creatinine excretion is an unreliable index of compliance in PD patients. Perit Dial Int (1997) 1.05
Ciliary neurotrophic factor enhances neuronal survival in embryonic rat hippocampal cultures. J Neurosci (1991) 1.05
Complementary and coordinated roles of the VEGFs and angiopoietins during normal and pathologic vascular formation. Cold Spring Harb Symp Quant Biol (2002) 1.05