Published in Dev Biol on December 01, 1985
The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3. Cell (1991) 2.56
Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J (1990) 2.54
Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain. Proc Natl Acad Sci U S A (1990) 1.94
Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA. J Cell Biol (1992) 1.87
Brain-derived neurotrophic factor and neurotrophin 3 mRNAs in the peripheral target fields of developing inner ear ganglia. Proc Natl Acad Sci U S A (1992) 1.76
Molecular cloning of a human gene that is a member of the nerve growth factor family. Proc Natl Acad Sci U S A (1990) 1.76
Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Müller cells temporarily rescues injured retinal ganglion cells. Proc Natl Acad Sci U S A (1998) 1.60
Estrogen-BDNF interactions: implications for neurodegenerative diseases. Front Neuroendocrinol (2006) 1.54
Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin 3. Proc Natl Acad Sci U S A (1991) 1.52
Abundant production of brain-derived neurotrophic factor by adult visceral epithelia. Implications for paracrine and target-derived Neurotrophic functions. Am J Pathol (1999) 1.37
Brain-derived neurotrophic factor signaling does not stimulate subventricular zone neurogenesis in adult mice and rats. J Neurosci (2008) 1.27
In vivo effect of brain-derived neurotrophic factor on the survival of developing dorsal root ganglion cells. EMBO J (1987) 1.25
An extended surface of binding to Trk tyrosine kinase receptors in NGF and BDNF allows the engineering of a multifunctional pan-neurotrophin. EMBO J (1993) 1.25
Expression of nerve growth factor in vivo from a defective herpes simplex virus 1 vector prevents effects of axotomy on sympathetic ganglia. Proc Natl Acad Sci U S A (1992) 1.21
Neurotrophin 3 is a mitogen for cultured neural crest cells. Proc Natl Acad Sci U S A (1992) 1.12
Dynamic plasticity: the role of glucocorticoids, brain-derived neurotrophic factor and other trophic factors. Neuroscience (2012) 1.10
Chimeric molecules with multiple neurotrophic activities reveal structural elements determining the specificities of NGF and BDNF. EMBO J (1991) 1.09
SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells. Mol Cell Biol (1993) 1.08
Neurotrophin 3 supports the survival of developing muscle sensory neurons in culture. Proc Natl Acad Sci U S A (1993) 1.01
Neurotrophins and their receptors in rat peripheral trigeminal system during maxillary nerve growth. J Cell Biol (1993) 0.95
Transient expression and transport of brain-derived neurotrophic factor in the male zebra finch's song system during vocal development. Proc Natl Acad Sci U S A (1998) 0.93
Differential effects of NGF and NT-3 on embryonic trigeminal axon growth patterns. J Comp Neurol (2000) 0.91
Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons. J Cell Biol (1993) 0.90
Shaping neurons: Long and short range effects of mature and proBDNF signalling upon neuronal structure. Neuropharmacology (2013) 0.87
Ectopic trkA expression mediates a NGF survival response in NGF-independent sensory neurons but not in parasympathetic neurons. J Cell Biol (1993) 0.86
Continuous brain-derived neurotrophic factor (BDNF) infusion after methylprednisolone treatment in severe spinal cord injury. J Korean Med Sci (2004) 0.83
Embryonic origin of gustatory cranial sensory neurons. Dev Biol (2007) 0.83
The effect of brain-derived neurotrophic factor on periodontal furcation defects. PLoS One (2014) 0.80
Experience and the ever-changing brain: what the transcriptome can reveal. Bioessays (2014) 0.79
Biomaterial Approaches to Enhancing Neurorestoration after Spinal Cord Injury: Strategies for Overcoming Inherent Biological Obstacles. Biomed Res Int (2015) 0.77
Novel approaches to the post-myocardial infarction/heart failure neural remodeling. Heart Fail Rev (2014) 0.76
Epigenetic Regulation of BDNF Gene during Development and Diseases. Int J Mol Sci (2017) 0.75
Recombinant fish neurotrophin-6 is a heparin-binding glycoprotein: implications for a role in axonal guidance. Biochem J (1997) 0.75
Crystals of the neurotrophins. Protein Sci (1996) 0.75
Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc Natl Acad Sci U S A (1995) 5.25
Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-Hydroxydopamine. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol (1968) 4.85
Physiology of the neurotrophins. Annu Rev Neurosci (1996) 4.82
Physiology of nerve growth factor. Physiol Rev (1980) 4.58
Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system. Genes Dev (2000) 4.07
Anterograde transport of brain-derived neurotrophic factor and its role in the brain. Nature (1997) 4.01
Neurotrophins are required for nerve growth during development. Nat Neurosci (2001) 3.96
Molecular cloning and expression of brain-derived neurotrophic factor. Nature (1989) 3.90
Purification of a new neurotrophic factor from mammalian brain. EMBO J (1982) 3.68
Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature (1992) 3.39
The heparin-binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival. EMBO J (1984) 3.39
NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression. Neuron (1990) 3.12
Neurotrophin-evoked rapid excitation through TrkB receptors. Nature (1999) 3.11
Neurotrophin-3: a neurotrophic factor related to NGF and BDNF. Science (1990) 2.91
Acute interstitial nephritis due to drugs: Review of the literature with a report of nine cases. Ann Intern Med (1980) 2.78
Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain. EMBO J (1990) 2.77
A BDNF autocrine loop in adult sensory neurons prevents cell death. Nature (1995) 2.75
BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra. Nature (1991) 2.70
Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family. Nature (1990) 2.69
Antidepressant-like effect of brain-derived neurotrophic factor (BDNF). Pharmacol Biochem Behav (1997) 2.67
The retrograde axonal transport of nerve growth factor. Brain Res (1974) 2.60
Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. Nature (1994) 2.57
Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J (1990) 2.54
Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve. Nature (1988) 2.47
Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection. J Cell Biol (1987) 2.40
Increase in tyrosine hydroxylase activity after reserpine administration. J Pharmacol Exp Ther (1969) 2.32
Induction of cell death by endogenous nerve growth factor through its p75 receptor. Nature (1996) 2.28
Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth. Neuron (1999) 2.26
Sodium ferric gluconate complex in sucrose is safe and effective in hemodialysis patients: North American Clinical Trial. Am J Kidney Dis (1999) 2.24
Disruption of the CNTF gene results in motor neuron degeneration. Nature (1993) 2.22
Light regulates expression of brain-derived neurotrophic factor mRNA in rat visual cortex. Proc Natl Acad Sci U S A (1992) 2.19
Nerve growth factor in sympathetic ganglia and corresponding target organs of the rat: correlation with density of sympathetic innervation. Proc Natl Acad Sci U S A (1983) 2.17
Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75. Science (1996) 2.15
The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons. Neuron (1992) 2.11
Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice. Proc Natl Acad Sci U S A (1996) 2.10
Some pharmacological actions of the beta-adrenolytic agent Ro 3-3528 (6,7-dimethyl-alpha-[(isopropylamino) methyl]-2-benzofuranmethanol Hydrochloride). Angiologica (1967) 2.10
A role for BDNF in mechanosensation. Nat Neurosci (1998) 2.08
Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature (1990) 2.06
Binding of brain-derived neurotrophic factor to the nerve growth factor receptor. Neuron (1990) 2.02
An electron microscopic study of selective, acute degeneration of sympathetic nerve terminals after administration of 6-hydroxydopamine. Experientia (1968) 1.98
Arrest of motor neuron disease in wobbler mice cotreated with CNTF and BDNF. Science (1994) 1.98
Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene. Proc Natl Acad Sci U S A (1997) 1.96
Selective induction by nerve growth factor of tyrosine hydroxylase and dopamine- -hydroxylase in the rat superior cervical ganglia. Proc Natl Acad Sci U S A (1971) 1.96
Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation. EMBO J (1985) 1.93
Relation between the rate of stimulation and the quantity of noradrenaline liberated from sympathetic nerve endings in the isolated perfused spleen of the cat. J Physiol (1965) 1.92
Factors affecting the prognosis in acute renal failure. A survey of 251 cases. Q J Med (1973) 1.91
Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA. J Cell Biol (1992) 1.87
Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4-phenylpyridinium ion toxicity: involvement of the glutathione system. J Neurochem (1992) 1.85
Dual site of action of phenoxybenzamine in the cat's spleen; blockade of alpha-adrenergic receptors and inhibition of re-uptake of neurally released norepinephrine. Experientia (1964) 1.83
Dissociated neurons regenerate into sciatic but not optic nerve explants in culture irrespective of neurotrophic factors. J Neurosci (1985) 1.82
Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor. Nature (1990) 1.80
Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons. Proc Natl Acad Sci U S A (1991) 1.79
NGF-mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: evidence for a physiological role of NGF in the brain? Brain Res (1983) 1.77
Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture. Neuron (1990) 1.77
Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor. Nature (1987) 1.76
Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation. J Neurosci (1999) 1.74
Brain-derived neurotrophic factor prevents neuronal death in vivo. Nature (1988) 1.74
Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity. Proc Natl Acad Sci U S A (1999) 1.73
Characterization of nerve growth factor (NGF) release from hippocampal neurons: evidence for a constitutive and an unconventional sodium-dependent regulated pathway. Eur J Neurosci (1995) 1.72
Increased tyrosine hydroxylase activity after drug-induced alteration of sympathetic transmission. Nature (1969) 1.72
Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues. EMBO J (1984) 1.71
Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature (1993) 1.71
Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR. EMBO J (1999) 1.70
The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus. Neuroreport (1993) 1.70
Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages. Proc Natl Acad Sci U S A (1987) 1.70
Sensory neurons in culture: changing requirements for survival factors during embryonic development. Proc Natl Acad Sci U S A (1980) 1.69
Central adrenergic neurones and the initiation and development of experimental hypertension. Experientia (1972) 1.67
Trans-synaptic induction of adrenal tyrosine hydroxylase. J Pharmacol Exp Ther (1969) 1.67
Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation. J Cell Biol (1992) 1.64
Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells. J Neurosci (1986) 1.64
Electronmicroscopic localization of 5-hydroxydopamine (3,4,5-trihydroxy-phenyl-ethylamine), a new 'false' sympathetic transmitter. Experientia (1967) 1.61
A crucial role for neurotrophin-3 in oligodendrocyte development. Nature (1994) 1.60
Nerve growth factor in mouse and rat serum: correlation between bioassay and radioimmunoassay determinations. Proc Natl Acad Sci U S A (1978) 1.59
Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus. Eur J Neurosci (1994) 1.57
Neurotrophin release by neurotrophins: implications for activity-dependent neuronal plasticity. Proc Natl Acad Sci U S A (1997) 1.55
Potentiation by tetraethylammonium of the response of the cat spleen to postganglionic sympathetic nerve stimulation. J Pharmacol Exp Ther (1967) 1.54
Association of intradialytic blood pressure changes with hospitalization and mortality rates in prevalent ESRD patients. Kidney Int (2007) 1.54
Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines. J Neurosci (1990) 1.53
Specificity of the retrograde axonal transport of nerve growth factor. Brain Res (1974) 1.52
The effects of ciliary neurotrophic factor on motor dysfunction in wobbler mouse motor neuron disease. Ann Neurol (1994) 1.52
Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration. J Cell Biol (1992) 1.51
Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids. Proc Natl Acad Sci U S A (1978) 1.50
Prenatal glucocorticoid exposure leads to offspring hyperglycaemia in the rat: studies with the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone. Diabetologia (1996) 1.49
Ciliary neurotrophic factor: pharmacokinetics and acute-phase response in rat. Ann Neurol (1994) 1.49
Purification of nerve growth factor antibodies by affinity chromatography. J Neurochem (1976) 1.49
Microglia-derived nerve growth factor causes cell death in the developing retina. Neuron (1998) 1.47
BDNF and NT-3 rescue sensory but not motoneurones following axotomy in the neonate. Neuroreport (1994) 1.47
ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons. Neuron (1989) 1.46
Chemical sympathectomy of the cat with 6-hydroxydopamine. J Pharmacol Exp Ther (1969) 1.46
Comparative studies on the effect of the nerve growth factor on sympathetic ganglia and adrenal medulla in newborn rats. Brain Res (1972) 1.44
Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex. Neuroscience (1999) 1.44