Published in EMBO J on May 15, 1997
Type III protein secretion systems in bacterial pathogens of animals and plants. Microbiol Mol Biol Rev (1998) 17.27
The virulence plasmid of Yersinia, an antihost genome. Microbiol Mol Biol Rev (1998) 5.78
The Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and disease. Philos Trans R Soc Lond B Biol Sci (1998) 2.53
Yersinia-induced apoptosis in vivo aids in the establishment of a systemic infection of mice. J Exp Med (1998) 2.39
Role of fraction 1 antigen of Yersinia pestis in inhibition of phagocytosis. Infect Immun (2002) 2.16
Molecular and cell biology aspects of plague. Proc Natl Acad Sci U S A (2000) 2.07
The Yersinia deadly kiss. J Bacteriol (1998) 2.03
Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts. J Cell Biol (1999) 2.00
The arginine finger domain of ExoT contributes to actin cytoskeleton disruption and inhibition of internalization of Pseudomonas aeruginosa by epithelial cells and macrophages. Infect Immun (2000) 1.90
Role of YopP in suppression of tumor necrosis factor alpha release by macrophages during Yersinia infection. Infect Immun (1998) 1.89
CAS proteins in normal and pathological cell growth control. Cell Mol Life Sci (2009) 1.84
Virulence role of V antigen of Yersinia pestis at the bacterial surface. Infect Immun (1999) 1.80
TyeA, a protein involved in control of Yop release and in translocation of Yersinia Yop effectors. EMBO J (1998) 1.78
A distinctive role for the Yersinia protein kinase: actin binding, kinase activation, and cytoskeleton disruption. Proc Natl Acad Sci U S A (2000) 1.74
Targeting mycobacterium protein tyrosine phosphatase B for antituberculosis agents. Proc Natl Acad Sci U S A (2010) 1.57
A semisynthetic Eph receptor tyrosine kinase provides insight into ligand-induced kinase activation. Chem Biol (2011) 1.54
Biochemical characterization of the Yersinia YopT protease: cleavage site and recognition elements in Rho GTPases. Proc Natl Acad Sci U S A (2003) 1.54
YopJ of Yersinia spp. is sufficient to cause downregulation of multiple mitogen-activated protein kinases in eukaryotic cells. Infect Immun (1999) 1.49
Enteropathogenic Escherichia coli mediates antiphagocytosis through the inhibition of PI 3-kinase-dependent pathways. EMBO J (2001) 1.48
A bacterial type III secretion system inhibits actin polymerization to prevent pore formation in host cell membranes. EMBO J (2001) 1.40
Cloning and characterization of secretory tyrosine phosphatases of Mycobacterium tuberculosis. J Bacteriol (2000) 1.38
Suppression of T and B lymphocyte activation by a Yersinia pseudotuberculosis virulence factor, yopH. J Exp Med (1999) 1.38
The YadA protein of Yersinia pseudotuberculosis mediates high-efficiency uptake into human cells under environmental conditions in which invasin is repressed. Infect Immun (2002) 1.37
Impaired integrin-mediated adhesion and signaling in fibroblasts expressing a dominant-negative mutant PTP1B. J Cell Biol (1998) 1.36
Processive phosphorylation: mechanism and biological importance. Cell Signal (2007) 1.31
Yersinia pseudotuberculosis-induced calcium signaling in neutrophils is blocked by the virulence effector YopH. Infect Immun (1999) 1.25
Translocated effectors of Yersinia. Curr Opin Microbiol (2009) 1.25
Involvement of focal adhesion kinase in invasin-mediated uptake. Proc Natl Acad Sci U S A (1998) 1.22
Small molecule tools for functional interrogation of protein tyrosine phosphatases. FEBS J (2012) 1.17
LcrV of Yersinia pestis enters infected eukaryotic cells by a virulence plasmid-independent mechanism. Infect Immun (1999) 1.16
Identification of SycN, YscX, and YscY, three new elements of the Yersinia yop virulon. J Bacteriol (1999) 1.15
The adaptor molecules LAT and SLP-76 are specifically targeted by Yersinia to inhibit T cell activation. J Exp Med (2005) 1.15
Manipulation of kinase signaling by bacterial pathogens. J Cell Biol (2011) 1.14
Delineation of regions of the Yersinia YopM protein required for interaction with the RSK1 and PRK2 host kinases and their requirement for interleukin-10 production and virulence. Infect Immun (2010) 1.12
Role of predicted transmembrane domains for type III translocation, pore formation, and signaling by the Yersinia pseudotuberculosis YopB protein. Infect Immun (2005) 1.09
Yersinia pseudotuberculosis produces a cytotoxic necrotizing factor. Infect Immun (2002) 1.08
Stringent homology-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions. Biol Direct (2014) 1.08
Yersinia enterocolitica induces apoptosis and inhibits surface molecule expression and cytokine production in murine dendritic cells. Infect Immun (2004) 1.06
The Salmonella effector SptP dephosphorylates host AAA+ ATPase VCP to promote development of its intracellular replicative niche. Cell Host Microbe (2009) 1.05
Protective efficacy of recombinant Yersinia outer proteins against bubonic plague caused by encapsulated and nonencapsulated Yersinia pestis. Infect Immun (1999) 1.04
A leucine-rich motif targets Pseudomonas aeruginosa ExoS within mammalian cells. Infect Immun (2005) 0.99
Attenuated Yersinia pseudotuberculosis carrier vaccine for simultaneous antigen-specific CD4 and CD8 T-cell induction. Infect Immun (2003) 0.98
A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion. EMBO J (1998) 0.98
Staphylococcal PknB as the first prokaryotic representative of the proline-directed kinases. PLoS One (2010) 0.97
Identifying Yersinia YopH-targeted signal transduction pathways that impair neutrophil responses during in vivo murine infection. Cell Host Microbe (2013) 0.97
Prediction of molecular mimicry candidates in human pathogenic bacteria. Virulence (2013) 0.96
OspE2 of Shigella sonnei is required for the maintenance of cell architecture of bacterium-infected cells. Infect Immun (2006) 0.96
Stringent DDI-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions. BMC Syst Biol (2013) 0.96
The Yersinia YopE and YopH type III effector proteins enhance bacterial proliferation following contact with eukaryotic cells. BMC Microbiol (2001) 0.92
YopH inhibits early pro-inflammatory cytokine responses during plague pneumonia. BMC Immunol (2010) 0.91
Entamoeba histolytica-induced dephosphorylation in host cells. Infect Immun (2002) 0.90
The cytotoxic necrotizing factor of Yersinia pseudotuberculosis (CNFY) enhances inflammation and Yop delivery during infection by activation of Rho GTPases. PLoS Pathog (2013) 0.89
Insight into bacterial virulence mechanisms against host immune response via the Yersinia pestis-human protein-protein interaction network. Infect Immun (2011) 0.88
Bicyclic benzofuran and indole-based salicylic acids as protein tyrosine phosphatase inhibitors. Bioorg Med Chem (2011) 0.87
Alternative endogenous protein processing via an autophagy-dependent pathway compensates for Yersinia-mediated inhibition of endosomal major histocompatibility complex class II antigen presentation. Infect Immun (2010) 0.85
Immune evasion by Yersinia enterocolitica: differential targeting of dendritic cell subpopulations in vivo. PLoS Pathog (2010) 0.85
Yersinia pseudotuberculosis efficiently escapes polymorphonuclear neutrophils during early infection. Infect Immun (2013) 0.84
Activation of protein tyrosine kinases by Coxiella burnetii: role in actin cytoskeleton reorganization and bacterial phagocytosis. Infect Immun (2001) 0.84
Attenuated Yersinia enterocolitica mutant strains exhibit differential virulence in cytokine-deficient mice: implications for the development of novel live carrier vaccines. Infect Immun (2003) 0.84
Role of IFN-gamma and IL-6 in a protective immune response to Yersinia enterocolitica in mice. BMC Microbiol (2008) 0.84
The GAP activity of type III effector YopE triggers killing of Yersinia in macrophages. PLoS Pathog (2014) 0.84
Integrin-mediated first signal for inflammasome activation in intestinal epithelial cells. J Immunol (2014) 0.83
Propofol inhibits pressure-stimulated macrophage phagocytosis via the GABAA receptor and dysregulation of p130cas phosphorylation. Am J Physiol Cell Physiol (2009) 0.83
Bacterial toxins and the immune system: show me the in vivo targets. J Exp Med (2005) 0.83
Type III secretion system-dependent translocation of ectopically expressed Yop effectors into macrophages by intracellular Yersinia pseudotuberculosis. Infect Immun (2011) 0.82
Cytotoxic necrotizing factor-Y boosts Yersinia effector translocation by activating Rac protein. J Biol Chem (2013) 0.81
Serogroup-related escape of Yersinia enterocolitica YopE from degradation by the ubiquitin-proteasome pathway. Infect Immun (2007) 0.80
Context-dependent protein folding of a virulence peptide in the bacterial and host environments: structure of an SycH-YopH chaperone-effector complex. Acta Crystallogr D Biol Crystallogr (2013) 0.80
Design and NMR studies of cyclic peptides targeting the N-terminal domain of the protein tyrosine phosphatase YopH. Chem Biol Drug Des (2010) 0.79
New potential eukaryotic substrates of the mycobacterial protein tyrosine phosphatase PtpA: hints of a bacterial modulation of macrophage bioenergetics state. Sci Rep (2015) 0.79
Microbe-host interactions in the alimentary tract: the gateway to understanding inflammatory bowel disease. Gut (2000) 0.79
Characterization of new substrates targeted by Yersinia tyrosine phosphatase YopH. PLoS One (2009) 0.78
Structural insight into effector proteins of Gram-negative bacterial pathogens that modulate the phosphoproteome of their host. Protein Sci (2015) 0.78
Host response during Yersinia pestis infection of human bronchial epithelial cells involves negative regulation of autophagy and suggests a modulation of survival-related and cellular growth pathways. Front Microbiol (2015) 0.78
Yersinia type III effectors perturb host innate immune responses. World J Biol Chem (2016) 0.77
Regulation of Yersinia protein kinase A (YpkA) kinase activity by multisite autophosphorylation and identification of an N-terminal substrate-binding domain in YpkA. J Biol Chem (2014) 0.77
Bacillus cereus Certhrax ADP-ribosylates vinculin to disrupt focal adhesion complexes and cell adhesion. J Biol Chem (2014) 0.76
PI3K/Akt pathway restricts epithelial adhesion of Dr + Escherichia coli by down-regulating the expression of decay accelerating factor. Exp Biol Med (Maywood) (2014) 0.75
Nitropropenyl benzodioxole, an anti-infective agent with action as a protein tyrosine phosphatase inhibitor. Open Med Chem J (2014) 0.75
Exploring Oxidovanadium(IV) Complexes as YopH Inhibitors: Mechanism of Action and Modeling Studies. ACS Med Chem Lett (2015) 0.75
Yersinia pseudotuberculosis Blocks Neutrophil Degranulation. Infect Immun (2016) 0.75
Yersinia enterocolitica YopH-deficient Strain Activates Neutrophil Recruitment to Peyer's patches Promoting Clearance of the Virulent Strain. Infect Immun (2016) 0.75
Yersinia pestis YopK inhibits bacterial adhesion to host cells by binding to the extracellular matrix adaptor protein matrilin-2. Infect Immun (2017) 0.75
Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal Biochem (1991) 16.18
Characterization of plasmids and plasmid-associated determinants of Yersinia enterocolitica pathogenesis. Infect Immun (1981) 13.80
Integrins and signal transduction pathways: the road taken. Science (1995) 10.71
Integrin function: molecular hierarchies of cytoskeletal and signaling molecules. J Cell Biol (1995) 6.74
MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell (1993) 6.55
Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cells. EMBO J (1994) 6.37
Translocation of a hybrid YopE-adenylate cyclase from Yersinia enterocolitica into HeLa cells. Mol Microbiol (1994) 5.82
Vinculin: a cytoskeletal target of the transforming protein of Rous sarcoma virus. Cell (1981) 5.74
Protein tyrosine phosphatase activity of an essential virulence determinant in Yersinia. Science (1990) 5.21
The cytotoxic protein YopE of Yersinia obstructs the primary host defence. Mol Microbiol (1990) 5.09
Inhibition of phagocytosis in Yersinia pseudotuberculosis: a virulence plasmid-encoded ability involving the Yop2b protein. Infect Immun (1988) 4.61
Tyrosine phosphate hydrolysis of host proteins by an essential Yersinia virulence determinant. Proc Natl Acad Sci U S A (1991) 4.57
Factors promoting acute and chronic diseases caused by yersiniae. Clin Microbiol Rev (1991) 4.53
Intracellular targeting of the Yersinia YopE cytotoxin in mammalian cells induces actin microfilament disruption. Infect Immun (1991) 4.46
The interaction of bacteria with mammalian cells. Annu Rev Cell Biol (1992) 3.62
Signal transduction in the mammalian cell during bacterial attachment and entry. Cell (1993) 3.41
Cell-surface-bound Yersinia translocate the protein tyrosine phosphatase YopH by a polarized mechanism into the target cell. Mol Microbiol (1995) 3.06
Electron microscopic evidence for in vivo extracellular localization of Yersinia pseudotuberculosis harboring the pYV plasmid. Infect Immun (1990) 2.95
Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases. Mol Cell Biol (1996) 2.94
p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase. J Biol Chem (1996) 2.77
Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas. Proc Natl Acad Sci U S A (1995) 2.67
The Yersinia yop regulon. Mol Microbiol (1989) 2.63
Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts. Mol Cell Biol (1993) 2.47
The Yersinia pseudotuberculosis adhesin YadA mediates intimate bacterial attachment to and entry into HEp-2 cells. Infect Immun (1993) 2.41
Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST. Mol Cell Biol (1996) 2.30
Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling. Cell (1996) 2.30
Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs. J Biol Chem (1995) 2.25
The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions. EMBO J (1995) 2.22
Cross-talk between bacterial pathogens and their host cells. Annu Rev Cell Dev Biol (1996) 2.21
Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix. J Biol Chem (1995) 2.17
Regulation and polarized transfer of the Yersinia outer proteins (Yops) involved in antiphagocytosis. Trends Microbiol (1994) 2.14
The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110. EMBO J (1991) 2.07
The Yersinia tyrosine phosphatase: specificity of a bacterial virulence determinant for phosphoproteins in the J774A.1 macrophage. J Exp Med (1992) 2.05
Expression, purification, and physicochemical characterization of a recombinant Yersinia protein tyrosine phosphatase. J Biol Chem (1992) 2.02
Several GTP-binding proteins, including p21c-H-ras, are preferred substrates of Pseudomonas aeruginosa exoenzyme S. J Biol Chem (1989) 2.00
Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling. Science (1996) 1.99
Adhesion-induced tyrosine phosphorylation of the p130 src substrate. J Cell Sci (1995) 1.95
Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase. J Biol Chem (1996) 1.90
Binding and internalization of microorganisms by integrin receptors. Trends Microbiol (1994) 1.83
Cloning the structural gene for the 49-kDa form of exoenzyme S (exoS) from Pseudomonas aeruginosa strain 388. J Biol Chem (1994) 1.82
Inhibition of the Fc receptor-mediated oxidative burst in macrophages by the Yersinia pseudotuberculosis tyrosine phosphatase. Infect Immun (1995) 1.79
Differential contribution of Yersinia enterocolitica virulence factors to evasion of microbicidal action of neutrophils. Infect Immun (1996) 1.69
Exploitation of host signal transduction pathways and cytoskeletal functions by invasive bacteria. Bioessays (1993) 1.52
Essential role of YopD in inhibition of the respiratory burst of macrophages by Yersinia enterocolitica. Infect Immun (1994) 1.49
The identification of p130cas-binding proteins and their role in cellular transformation. Oncogene (1996) 1.26
The role of protein tyrosine phosphorylation in integrin-mediated gene induction in monocytes. J Cell Biol (1994) 1.23
Salmonella entry into mammalian cells: different yet converging signal transduction pathways? Trends Cell Biol (1994) 0.96
How pathogens exploit interactions mediated by SH3 domains. Chem Biol (1996) 0.93
Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease. Science (2000) 4.22
Yops of Yersinia spp. pathogenic for humans. Infect Immun (1993) 2.92
Use of site-specific recombination as a probe of DNA structure and metabolism in vivo. J Mol Biol (1987) 2.84
Nucleotide sequence of the Yersinia enterocolitica ail gene and characterization of the Ail protein product. J Bacteriol (1990) 2.84
YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-alpha production and downregulation of the MAP kinases p38 and JNK. Mol Microbiol (1998) 2.83
Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector. Science (1999) 2.78
The RhoGAP activity of the Yersinia pseudotuberculosis cytotoxin YopE is required for antiphagocytic function and virulence. Mol Microbiol (2000) 2.56
A secreted protein tyrosine phosphatase with modular effector domains in the bacterial pathogen Salmonella typhimurium. Mol Microbiol (1996) 2.36
Cross-talk between bacterial pathogens and their host cells. Annu Rev Cell Dev Biol (1996) 2.21
Recombination and balanced chromosome polymorphism suggested by DNA sequences 5' to the human delta-globin gene. Proc Natl Acad Sci U S A (1983) 2.11
The Yersinia tyrosine phosphatase YopH targets a novel adhesion-regulated signalling complex in macrophages. Cell Microbiol (2000) 1.53
YopJ of Yersinia spp. is sufficient to cause downregulation of multiple mitogen-activated protein kinases in eukaryotic cells. Infect Immun (1999) 1.49
Cre-lox recombination in Escherichia coli cells. Mechanistic differences from the in vitro reaction. J Mol Biol (1992) 1.45
A bacterial type III secretion system inhibits actin polymerization to prevent pore formation in host cell membranes. EMBO J (2001) 1.40
Identification of an amino-terminal substrate-binding domain in the Yersinia tyrosine phosphatase that is required for efficient recognition of focal adhesion targets. Mol Microbiol (1998) 1.13
CAS/Crk signalling mediates uptake of Yersinia into human epithelial cells. Cell Microbiol (2000) 1.08
Identification of residues in the N-terminal domain of the Yersinia tyrosine phosphatase that are critical for substrate recognition. J Biol Chem (2000) 1.00
Role of macrophage apoptosis in the pathogenesis of Yersinia. Curr Top Microbiol Immunol (2005) 1.00
Analysis of amplified DNAs from drug-resistant Leishmania by orthogonal-field-alternation gel electrophoresis. The effect of size and topology on mobility. J Biol Chem (1989) 0.93
Microbial pathogenesis and tyrosine dephosphorylation: surprising 'bedfellows'. Mol Microbiol (1991) 0.78