Published in Mol Biochem Parasitol on July 01, 1997
Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity. Mol Biochem Parasitol (2009) 2.95
Brugia malayi excreted/secreted proteins at the host/parasite interface: stage- and gender-specific proteomic profiling. PLoS Negl Trop Dis (2009) 1.88
The abundant larval transcript-1 and -2 genes of Brugia malayi encode stage-specific candidate vaccine antigens for filariasis. Infect Immun (2000) 1.50
Immune responses in hookworm infections. Clin Microbiol Rev (2001) 1.39
On the extent and origins of genic novelty in the phylum Nematoda. PLoS Negl Trop Dis (2008) 1.25
A deep sequencing approach to comparatively analyze the transcriptome of lifecycle stages of the filarial worm, Brugia malayi. PLoS Negl Trop Dis (2011) 1.23
Identification of potential vaccine and drug target candidates by expressed sequence tag analysis and immunoscreening of Onchocerca volvulus larval cDNA libraries. Infect Immun (2000) 1.14
Nippocystatin, a cysteine protease inhibitor from Nippostrongylus brasiliensis, inhibits antigen processing and modulates antigen-specific immune response. Infect Immun (2001) 1.10
Development of a recombinant antigen vaccine against infection with the filarial worm Onchocerca volvulus. Infect Immun (2001) 1.01
Transcriptomes and pathways associated with infectivity, survival and immunogenicity in Brugia malayi L3. BMC Genomics (2009) 0.99
Analysis of genes expressed at the infective larval stage validates utility of Litomosoides sigmodontis as a murine model for filarial vaccine development. Infect Immun (2000) 0.92
Intranasal immunization with recombinant Ascaris suum 14-kilodalton antigen coupled with cholera toxin B subunit induces protective immunity to A. suum infection in mice. Infect Immun (2001) 0.90
Transcription profiling reveals stage- and function-dependent expression patterns in the filarial nematode Brugia malayi. BMC Genomics (2012) 0.88
Parasitic helminth cystatin inhibits DSS-induced intestinal inflammation via IL-10(+)F4/80(+) macrophage recruitment. Korean J Parasitol (2011) 0.82
Identification and cloning of a novel tetraspanin (TSP) homologue from Brugia malayi. DNA Seq (2008) 0.81
Inter and intra-specific diversity of parasites that cause lymphatic filariasis. Infect Genet Evol (2012) 0.79
The secreted triose phosphate isomerase of Brugia malayi is required to sustain microfilaria production in vivo. PLoS Pathog (2014) 0.78
Differential Evolutionary Selection and Natural Evolvability Observed in ALT Proteins of Human Filarial Parasites. PLoS One (2016) 0.75
Phylogeny of Wolbachia in filarial nematodes. Proc Biol Sci (1998) 3.35
Th2 responses without atopy: immunoregulation in chronic helminth infections and reduced allergic disease. Trends Immunol (2001) 2.94
Th1-Th2: reliable paradigm or dangerous dogma? Immunol Today (1997) 2.83
Tetracycline therapy targets intracellular bacteria in the filarial nematode Litomosoides sigmodontis and results in filarial infertility. J Clin Invest (1999) 2.78
Ultrasequencing of the meiofaunal biosphere: practice, pitfalls and promises. Mol Ecol (2010) 2.64
Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell-to-cell contact. Eur J Immunol (2000) 1.78
Elevated cellular immune responses and interferon-gamma release after long-term diethylcarbamazine treatment of patients with human lymphatic filariasis. J Infect Dis (1995) 1.74
Molecular genealogy of some nematode taxa as based on cytochrome c and globin amino acid sequences. Mol Phylogenet Evol (1994) 1.67
Epitope specificity of the T cell proliferative response to lysozyme: proliferative T cells react predominantly to different determinants from those recognized by B cells. Eur J Immunol (1980) 1.62
A Brugia malayi homolog of macrophage migration inhibitory factor reveals an important link between macrophages and eosinophil recruitment during nematode infection. J Immunol (2001) 1.60
Differential expression of IgE and IgG4 specific antibody responses in asymptomatic and chronic human filariasis. J Immunol (1993) 1.51
The abundant larval transcript-1 and -2 genes of Brugia malayi encode stage-specific candidate vaccine antigens for filariasis. Infect Immun (2000) 1.50
Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses. Eur J Immunol (2000) 1.49
The Wolbachia Genome Consortium. Microb Comp Genomics (1999) 1.46
Identification of tgh-2, a filarial nematode homolog of Caenorhabditis elegans daf-7 and human transforming growth factor beta, expressed in microfilarial and adult stages of Brugia malayi. Infect Immun (2000) 1.46
Bm-CPI-2, a cystatin homolog secreted by the filarial parasite Brugia malayi, inhibits class II MHC-restricted antigen processing. Curr Biol (2001) 1.43
Identification and characterisation of a Leishmania donovani antigen belonging to the 70-kDa heat-shock protein family. Eur J Biochem (1990) 1.42
Infection of IL-4-deficient mice with the parasitic nematode Brugia malayi demonstrates that host resistance is not dependent on a T helper 2-dominated immune response. J Immunol (1995) 1.40
Chitinases and chitinase-like proteins: potential therapeutic targets for the treatment of T-helper type 2 allergies. Clin Exp Allergy (2009) 1.33
Molecular analysis of nematode diversity and the evolution of parasitism. Parasitol Today (1999) 1.32
Immunological focusing by th mouse major histocompatibility complex: mouse strains confronted with distantly related lysozymes confine their attention to very few epitopes. Eur J Immunol (1982) 1.29
APC from mice harbouring the filarial nematode, Brugia malayi, prevent cellular proliferation but not cytokine production. Int Immunol (1996) 1.28
Expression and immune recognition of Brugia malayi VAL-1, a homologue of vespid venom allergens and Ancylostoma secreted proteins. Mol Biochem Parasitol (2001) 1.26
Filarial-specific IgG4 response correlates with active Wuchereria bancrofti infection. J Immunol (1990) 1.26
Shared carbohydrate epitopes on distinct surface and secreted antigens of the parasitic nematode Toxocara canis. J Immunol (1987) 1.25
Adult and microfilarial stages of the filarial parasite Brugia malayi stimulate contrasting cytokine and Ig isotype responses in BALB/c mice. J Immunol (1994) 1.20
Nippostrongylus brasiliensis: cytokine responses and nematode expulsion in normal and IL-4-deficient mice. Exp Parasitol (1996) 1.20
Serine proteinase inhibitors from nematodes and the arms race between host and pathogen. Trends Biochem Sci (2001) 1.19
Multicentre laboratory evaluation of Brugia Rapid dipstick test for detection of brugian filariasis. Trop Med Int Health (2003) 1.18
Immunological genomics of Brugia malayi: filarial genes implicated in immune evasion and protective immunity. Parasite Immunol (2001) 1.18
Conservation of long-range synteny and microsynteny between the genomes of two distantly related nematodes. Genome Biol (2002) 1.18
Caenorhabditis elegans as a model for parasitic nematodes. Int J Parasitol (1998) 1.17
Characterization of surface and excretory-secretory antigens of Toxocara canis infective larvae. Parasite Immunol (1984) 1.17
A novel member of the transforming growth factor-beta (TGF-beta) superfamily from the filarial nematodes Brugia malayi and B. pahangi. Exp Parasitol (1998) 1.16
Identification of abundantly expressed novel and conserved genes from the infective larval stage of Toxocara canis by an expressed sequence tag strategy. Infect Immun (1999) 1.15
T cell responsiveness correlates differentially with antibody isotype levels in clinical and asymptomatic filariasis. J Infect Dis (1993) 1.14
Immunology of human helminth infection. Int Arch Allergy Immunol (1996) 1.12
Depression of antigen-specific interleukin-5 and interferon-gamma responses in human lymphatic filariasis as a function of clinical status and age. J Infect Dis (1997) 1.11
An abundant, trans-spliced mRNA from Toxocara canis infective larvae encodes a 26-kDa protein with homology to phosphatidylethanolamine-binding proteins. J Biol Chem (1995) 1.10
Helminth C-type lectins and host-parasite interactions. Parasitol Today (2000) 1.09
Toxocara canis: a labile antigenic surface coat overlying the epicuticle of infective larvae. Exp Parasitol (1992) 1.09
A novel serpin expressed by blood-borne microfilariae of the parasitic nematode Brugia malayi inhibits human neutrophil serine proteinases. Blood (1999) 1.08
Nematode surface coats: actively evading immunity. Parasitol Today (1992) 1.08
The filarial genome project: analysis of the nuclear, mitochondrial and endosymbiont genomes of Brugia malayi. Int J Parasitol (2000) 1.07
Age-specific acquisition of immunity to infective larvae in a bancroftian filariasis endemic area of Papua New Guinea. Parasite Immunol (1991) 1.06
An abundantly expressed mucin-like protein from Toxocara canis infective larvae: the precursor of the larval surface coat glycoproteins. Proc Natl Acad Sci U S A (1996) 1.05
A novel C-type lectin secreted by a tissue-dwelling parasitic nematode. Curr Biol (1999) 1.04
Specificity of surface molecules of adult Brugia parasites: cross-reactivity with antibody from Wuchereria, Onchocerca and other human filarial infections. Trop Med Parasitol (1985) 1.04
Biochemical properties of larval excretory-secretory glycoproteins of the parasitic nematode Toxocara canis. Mol Biochem Parasitol (1986) 1.04
Differential decline in filaria-specific IgG1, IgG4, and IgE antibodies in Brugia malayi-infected patients after diethylcarbamazine chemotherapy. J Infect Dis (1995) 1.03
Acquired immune heterogeneity and its sources in human helminth infection. Parasitology (2010) 1.03
Restricted sets of parasite antigens from the surface of different stages and sexes of the nematode parasite Nippostrongylus brasiliensis. Immunology (1983) 1.03
A family of secreted mucins from the parasitic nematode Toxocara canis bears diverse mucin domains but shares similar flanking six-cysteine repeat motifs. J Biol Chem (2000) 1.03
Identification of the major soluble cuticular glycoprotein of lymphatic filarial nematode parasites (gp29) as a secretory homolog of glutathione peroxidase. Proc Natl Acad Sci U S A (1992) 1.00
Characterization of nematode glycoproteins: the major O-glycans of Toxocara excretory-secretory antigens are O-methylated trisaccharides. Glycobiology (1991) 1.00
Requirement for in vivo production of IL-4, but not IL-10, in the induction of proliferative suppression by filarial parasites. J Immunol (1998) 0.99
Forms and functions of nematode surfaces. Exp Parasitol (1993) 0.99
Diagnosis of human toxocariasis by antigen capture enzyme linked immunosorbent assay. J Clin Pathol (1993) 0.98
The serpin secreted by Brugia malayi microfilariae, Bm-SPN-2, elicits strong, but short-lived, immune responses in mice and humans. J Immunol (2000) 0.97
Molecules on the surface of parasitic nematodes as probes of the immune response in infection. Immunol Rev (1982) 0.97
Repeated patent infection of adult dogs with Toxocara canis. J Helminthol (1984) 0.96
Phosphorylcholine-bearing antigens in filarial nematode parasites: analysis of somatic extracts, in-vitro secretions and infection sera from Brugia malayi and B. pahangi. Parasite Immunol (1987) 0.96
Conditions for the development of IgM- and IgG-antibody-secreting cells from primed mouse splenocytes in vitro. Immunology (1977) 0.96
Antibody responses to filarial infective larvae are not dominated by the IgG4 isotype. Parasite Immunol (1998) 0.95
The individual and the information problem. Nature (1973) 0.95
Identification of a new C-type lectin, TES-70, secreted by infective larvae of Toxocara canis, which binds to host ligands. Parasitology (2000) 0.94
Species-specific and common epitopes on the secreted and surface antigens of Toxocara cati and Toxocara canis infective larvae. Parasite Immunol (1987) 0.94
Identification, synthesis and immunogenicity of cuticular collagens from the filarial nematodes Brugia malayi and Brugia pahangi. Mol Biochem Parasitol (1989) 0.94
Heat shock cognate 70 is a prominent immunogen in Brugian filariasis. J Immunol (1989) 0.94
Characterisation of an immunodominant glycoprotein antigen of Onchocerca volvulus with homologues in other filarial nematodes and Caenorhabditis elegans. Mol Biochem Parasitol (1995) 0.93
daf-7-related TGF-beta homologues from Trichostrongyloid nematodes show contrasting life-cycle expression patterns. Parasitology (2009) 0.93
Requirement for in vivo production of IL-4, but not IL-10, in the induction of proliferative suppression by filarial parasites. J Immunol (1998) 0.93
Cuticular localisation and turnover of the major surface glycoprotein (gp29) of adult Brugia malayi. Mol Biochem Parasitol (1990) 0.92
Adults acquire filarial infection more rapidly than children: a study in Indonesian transmigrants. Parasitology (2001) 0.91
Expressed sequence tag survey of gene expression in the scab mite Psoroptes ovis--allergens, proteases and free-radical scavengers. Parasitology (2003) 0.91
Ascaris suum-derived products induce human neutrophil activation via a G protein-coupled receptor that interacts with the interleukin-8 receptor pathway. Infect Immun (2001) 0.90
Secreted and circulating antigens of the filarial parasite Brugia pahangi: analysis of in vitro released components and detection of parasite products in vivo. Mol Biochem Parasitol (1985) 0.90
Brugia pahangi and Brugia malayi: a surface-associated glycoprotein (gp15/400) is composed of multiple tandemly repeated units and processed from a 400-kDa precursor. Exp Parasitol (1993) 0.90
Characterization of proteolytic enzymes from larval and adult Nippostrongylus brasiliensis. Parasitology (1991) 0.89
Cross-reactive surface antigens on three stages of Brugia malayi, B. pahangi and B. timori. Parasitology (1983) 0.89
Toxocara canis: monoclonal antibodies to carbohydrate epitopes of secreted (TES) antigens localize to different secretion-related structures in infective larvae. Exp Parasitol (1992) 0.89
The antibody recognition profiles of humans naturally infected with Ascaris lumbricoides. Parasite Immunol (1989) 0.89
Stage-specific antigens of Nematospiroides dubius. Immunology (1984) 0.89
Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4. Parasite Immunol (2011) 0.88
Towards a filariasis-free community: evaluation of filariasis control over an eleven year period in Flores, Indonesia. Trans R Soc Trop Med Hyg (1990) 0.88
Persistent airway hyper-responsiveness and inflammation in Toxocara canis-infected BALB/c mice. Clin Exp Allergy (2005) 0.88
Ir-gene control of T cell proliferative responses: two distinct expressions of the genetically nonresponsive state. Eur J Immunol (1980) 0.87
cDNA clones of Onchocerca volvulus low molecular weight antigens provide immunologically specific diagnostic probes. Mol Biochem Parasitol (1991) 0.87
A cDNA encoding Tc-MUC-5, a mucin from Toxocara canis larvae identified by expression screening. Acta Trop (2001) 0.87
Surface antigens of a filarial nematode: analysis of adult Brugia pahangi surface components and their use in monoclonal antibody production. Mol Biochem Parasitol (1985) 0.86
Toxocariasis: a practical approach to management of ocular disease. Eye (Lond) (1988) 0.86
Genomics and the biology of parasites. Bioessays (1999) 0.86
Detection of circulating parasite antigen and specific antibody in Toxocara canis infections. Clin Exp Immunol (1988) 0.86
Primary structure of and immunoglobulin E response to the repeat subunit of gp15/400 from human lymphatic filarial parasites. Infect Immun (1993) 0.86
MHC and non-MHC-restricted recognition of filarial surface antigens in mice transplanted with adult Brugia malayi parasites. J Immunol (1990) 0.85
Differential antibody responses to Plasmodium falciparum and P. vivax circumsporozoite proteins in a human population. J Clin Microbiol (1989) 0.85
A hemoglobin with an optical function. J Biol Chem (2000) 0.85
Comparison of isolates and species of Toxocara and Toxascaris by biosynthetic labelling of somatic and ES proteins from infective larvae. Parasitology (1991) 0.85