Published in Infect Immun on July 01, 2000
Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity. Mol Biochem Parasitol (2009) 2.95
Brugia malayi excreted/secreted proteins at the host/parasite interface: stage- and gender-specific proteomic profiling. PLoS Negl Trop Dis (2009) 1.88
Longitudinal monitoring of the development of antifilarial antibodies and acquisition of Wuchereria bancrofti in a highly endemic area of Haiti. PLoS Negl Trop Dis (2012) 1.42
On the extent and origins of genic novelty in the phylum Nematoda. PLoS Negl Trop Dis (2008) 1.25
Novel phage display-based subtractive screening to identify vaccine candidates of Brugia malayi. Infect Immun (2004) 1.24
A deep sequencing approach to comparatively analyze the transcriptome of lifecycle stages of the filarial worm, Brugia malayi. PLoS Negl Trop Dis (2011) 1.23
Stage-specific proteomic expression patterns of the human filarial parasite Brugia malayi and its endosymbiont Wolbachia. Proc Natl Acad Sci U S A (2011) 1.20
Evaluation of Wuchereria bancrofti GST as a vaccine candidate for lymphatic filariasis. PLoS Negl Trop Dis (2009) 1.18
Heterologous expression of the filarial nematode alt gene products reveals their potential to inhibit immune function. BMC Biol (2005) 1.08
Brugia malayi: comparison of protective immune responses induced by Bm-alt-2 DNA, recombinant Bm-ALT-2 protein and prime-boost vaccine regimens in a jird model. Exp Parasitol (2007) 1.06
A reverse transcriptase-PCR assay for detecting filarial infective larvae in mosquitoes. PLoS Negl Trop Dis (2008) 1.02
Needles in the EST haystack: large-scale identification and analysis of excretory-secretory (ES) proteins in parasitic nematodes using expressed sequence tags (ESTs). PLoS Negl Trop Dis (2008) 1.00
Mice intranasally immunized with a recombinant 16-kilodalton antigen from roundworm Ascaris parasites are protected against larval migration of Ascaris suum. Infect Immun (2003) 0.96
Resistance and susceptibility to filarial infection with Litomosoides sigmodontis are associated with early differences in parasite development and in localized immune reactions. Infect Immun (2003) 0.95
A comprehensive, model-based review of vaccine and repeat infection trials for filariasis. Clin Microbiol Rev (2013) 0.95
Biochemical characterization and evaluation of a Brugia malayi small heat shock protein as a vaccine against lymphatic filariasis. PLoS One (2012) 0.94
Deletion of parasite immune modulatory sequences combined with immune activating signals enhances vaccine mediated protection against filarial nematodes. PLoS Negl Trop Dis (2012) 0.93
Analysis of genes expressed at the infective larval stage validates utility of Litomosoides sigmodontis as a murine model for filarial vaccine development. Infect Immun (2000) 0.92
Multivalent fusion protein vaccine for lymphatic filariasis. Vaccine (2012) 0.92
Intranasal immunization with recombinant Ascaris suum 14-kilodalton antigen coupled with cholera toxin B subunit induces protective immunity to A. suum infection in mice. Infect Immun (2001) 0.90
Immune response studies with Wuchereria bancrofti vespid allergen homologue (WbVAH) in human lymphatic filariasis. Parasitol Res (2007) 0.89
Transcription profiling reveals stage- and function-dependent expression patterns in the filarial nematode Brugia malayi. BMC Genomics (2012) 0.88
Concurrent transcriptional profiling of Dirofilaria immitis and its Wolbachia endosymbiont throughout the nematode life cycle reveals coordinated gene expression. BMC Genomics (2014) 0.86
Helminths: Immunoregulation and Inflammatory Diseases-Which Side Are Trichinella spp. and Toxocara spp. on? J Parasitol Res (2013) 0.85
Single multivalent vaccination boosted by trickle larval infection confers protection against experimental lymphatic filariasis. Vaccine (2013) 0.83
The Onchocerca volvulus cysteine proteinase inhibitor, Ov-CPI-2, is a target of protective antibody response that increases with age. PLoS Negl Trop Dis (2010) 0.82
Granuloma formation around filarial larvae triggered by host responses to an excretory/secretory antigen. Infect Immun (2010) 0.82
Identification and cloning of a novel tetraspanin (TSP) homologue from Brugia malayi. DNA Seq (2008) 0.81
Immunization of Mastomys coucha with Brugia malayi recombinant trehalose-6-phosphate phosphatase results in significant protection against homologous challenge infection. PLoS One (2013) 0.80
Brugia pahangi: immunization with early L3 ES alters parasite migration, and reduces microfilaremia and lymphatic lesion formation in gerbils (Meriones unguiculatus). Exp Parasitol (2013) 0.80
Protective immune responses to biolistic DNA vaccination of Brugia malayi abundant larval transcript-2. Vaccine (2012) 0.79
Potential of recombinant inorganic pyrophosphatase antigen as a new vaccine candidate against Baylisascaris schroederi in mice. Vet Res (2013) 0.79
Production and single-step purification of Brugia malayi abundant larval transcript (ALT-2) using hydrophobic interaction chromatography. J Ind Microbiol Biotechnol (2010) 0.79
Update on Lymphatic Filarial Infections. Curr Infect Dis Rep (2002) 0.79
The secreted triose phosphate isomerase of Brugia malayi is required to sustain microfilaria production in vivo. PLoS Pathog (2014) 0.78
Vaccination of Gerbils with Bm-103 and Bm-RAL-2 Concurrently or as a Fusion Protein Confers Consistent and Improved Protection against Brugia malayi Infection. PLoS Negl Trop Dis (2016) 0.78
Molecular characterization and evaluation of Onchocerca volvulus-secreted larval acidic protein 1 (SLAP1) as a putative vaccine candidate on endemic population of lymphatic filariasis. Parasitol Res (2013) 0.78
Molecular cloning, purification and characterisation of myosin of human lymphatic filarial parasite Brugia malayi. Parasitol Res (2007) 0.77
Crucial epitopes of Wuchereria bancrofti abundant larval transcript recognized in natural infection. Eur J Clin Microbiol Infect Dis (2010) 0.76
Human immune responses to infective stage larval-specific chitinase of filarial parasite, Onchocerca volvulus, Ov-CHI-1. Filaria J (2003) 0.75
Humans from Wuchereria bancrofti endemic area elicit substantial immune response to proteins of the filarial parasite Brugia malayi and its endosymbiont Wolbachia. Parasit Vectors (2017) 0.75
Differential Evolutionary Selection and Natural Evolvability Observed in ALT Proteins of Human Filarial Parasites. PLoS One (2016) 0.75
Prospects and challenges of CRISPR/Cas genome editing for the study and control of neglected vector-borne nematode diseases. FEBS J (2016) 0.75
Immunization with Brugia malayi Myosin as Heterologous DNA Prime Protein Boost Induces Protective Immunity against B. malayi Infection in Mastomys coucha. PLoS One (2016) 0.75
KinFin: Software for Taxon-Aware Analysis of Clustered Protein Sequences. G3 (Bethesda) (2017) 0.75
Immunogenicity of Brugia malayi Abundant Larval Transcript-2, a potential filarial vaccine candidate expressed in tobacco. Plant Cell Rep (2013) 0.75
Re-assessing the global prevalence and distribution of lymphatic filariasis. Parasitology (1996) 3.80
Lymphatic filariasis: the disease and its control. Fifth report of the WHO Expert Committee on Filariasis. World Health Organ Tech Rep Ser (1992) 2.09
Development of subperiodic Brugia malayi in the jird, Meriones unguiculatus, with notes on infections in other rodents. J Parasitol (1970) 1.61
Differential expression of IgE and IgG4 specific antibody responses in asymptomatic and chronic human filariasis. J Immunol (1993) 1.51
The Wellcome Trust Lecture. Infection and disease in lymphatic filariasis: an immunological perspective. Parasitology (1992) 1.51
T-cell activation and the balance of antibody isotypes in human lymphatic filariasis. Parasitol Today (1995) 1.45
Immunological tolerance: The key feature in human filariasis? Parasitol Today (1991) 1.36
IgG antibody subclasses in human filariasis. Differential subclass recognition of parasite antigens correlates with different clinical manifestations of infection. J Immunol (1987) 1.32
Vaccination with recombinant filarial paramyosin induces partial immunity to Brugia malayi infection in jirds. J Immunol (1993) 1.19
Brugia malayi: vaccination of jirds with 60cobalt-attenuated infective stage larvae protects against homologous challenge. Am J Trop Med Hyg (1985) 1.17
An abundant, trans-spliced mRNA from Toxocara canis infective larvae encodes a 26-kDa protein with homology to phosphatidylethanolamine-binding proteins. J Biol Chem (1995) 1.10
A novel serpin expressed by blood-borne microfilariae of the parasitic nematode Brugia malayi inhibits human neutrophil serine proteinases. Blood (1999) 1.08
Protective immunity in bancroftian filariasis. Selective recognition of a 43-kD larval stage antigen by infection-free individuals in an endemic area. J Clin Invest (1989) 1.07
Age-specific acquisition of immunity to infective larvae in a bancroftian filariasis endemic area of Papua New Guinea. Parasite Immunol (1991) 1.06
Differentially expressed, abundant trans-spliced cDNAs from larval Brugia malayi. Mol Biochem Parasitol (1997) 1.04
Characterization of an Onchocerca volvulus L3-specific larval antigen, Ov-ALT-1. Mol Biochem Parasitol (1998) 0.98
Vaccination against helminth parasites--the ultimate challenge for vaccinologists? Immunol Rev (1999) 0.98
Immune responses to Brugia malayi paramyosin in rodents after DNA vaccination. Vaccine (1999) 0.95
Antibody responses to filarial infective larvae are not dominated by the IgG4 isotype. Parasite Immunol (1998) 0.95
The endemic normal in lymphatic filariasis: A static concept. Parasitol Today (1991) 0.95
Molecular cloning and serological characterization of a Brugia malayi pepsin inhibitor homolog. Mol Biochem Parasitol (1993) 0.94
Molecular cloning of a developmentally regulated protein isolated from excretory-secretory products of larval Dirofilaria immitis. Mol Biochem Parasitol (1996) 0.93
Identification of paramyosin as a potential protective antigen against Brugia malayi infection in jirds. Mol Biochem Parasitol (1991) 0.91
Failure of highly immunogenic filarial proteins to provide host-protective immunity. Exp Parasitol (1999) 0.91
Age specific patterns of change in the dynamics of Wuchereria bancrofti infection in Papua New Guinea. Am J Trop Med Hyg (1991) 0.90
Acanthocheilonema viteae: characterization of a molt-associated excretory/secretory 18-kDa protein. Exp Parasitol (1999) 0.88
Purification and characterization of three larval excretory-secretory proteins of Dirofilaria immitis. Mol Biochem Parasitol (1996) 0.87
Immunity and the prospects for vaccination against filariasis. Immunobiology (1992) 0.84
Deep within the filarial genome: progress of the filarial genome project. Parasitol Today (1999) 0.83
Metabolic labeling of Dirofilaria immitis third- and fourth-stage larvae and their excretory-secretory products. J Parasitol (1991) 0.82
Developmentally regulated expression and secretion of a polymorphic antigen by Onchocerca infective-stage larvae. Mol Biochem Parasitol (1990) 0.81
Onchocerca spp: a "family" of secreted acidic proteins expressed by infective larvae in blackflies. Exp Parasitol (1995) 0.79
Protective immunity in lymphatic filariasis. Exp Parasitol (1989) 0.79
The transcriptional landscape of the mammalian genome. Science (2005) 37.63
Cold machine perfusion versus static cold storage of kidneys donated after cardiac death: a UK multicenter randomized controlled trial. Am J Transplant (2010) 2.97
Th2 responses without atopy: immunoregulation in chronic helminth infections and reduced allergic disease. Trends Immunol (2001) 2.94
Th1-Th2: reliable paradigm or dangerous dogma? Immunol Today (1997) 2.83
Diagnosis and initial management of blunt pancreatic trauma: guidelines from a multiinstitutional review. Ann Surg (1998) 2.07
Intramural hematoma of the duodenum. Arch Surg (1988) 1.79
Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell-to-cell contact. Eur J Immunol (2000) 1.78
Elevated cellular immune responses and interferon-gamma release after long-term diethylcarbamazine treatment of patients with human lymphatic filariasis. J Infect Dis (1995) 1.74
Epitope specificity of the T cell proliferative response to lysozyme: proliferative T cells react predominantly to different determinants from those recognized by B cells. Eur J Immunol (1980) 1.62
A Brugia malayi homolog of macrophage migration inhibitory factor reveals an important link between macrophages and eosinophil recruitment during nematode infection. J Immunol (2001) 1.60
Pathophysiology of congenital diaphragmatic hernia II: the fetal lamb CDH model is surfactant deficient. J Pediatr Surg (1992) 1.55
Differential expression of IgE and IgG4 specific antibody responses in asymptomatic and chronic human filariasis. J Immunol (1993) 1.51
Phosphorylation of an endogenous membrane protein by an endogenous, membrane-associated cyclic adenosine 3',5'-monophosphate-dependent protein kinase in human erythrocyte ghosts. J Biol Chem (1972) 1.51
Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses. Eur J Immunol (2000) 1.49
Identification of tgh-2, a filarial nematode homolog of Caenorhabditis elegans daf-7 and human transforming growth factor beta, expressed in microfilarial and adult stages of Brugia malayi. Infect Immun (2000) 1.46
The visualization of Meckel's diverticulum with 99mTc-pertechnetate. Surgery (1970) 1.45
Bm-CPI-2, a cystatin homolog secreted by the filarial parasite Brugia malayi, inhibits class II MHC-restricted antigen processing. Curr Biol (2001) 1.43
Infection of IL-4-deficient mice with the parasitic nematode Brugia malayi demonstrates that host resistance is not dependent on a T helper 2-dominated immune response. J Immunol (1995) 1.40
Chitinases and chitinase-like proteins: potential therapeutic targets for the treatment of T-helper type 2 allergies. Clin Exp Allergy (2009) 1.33
Antigen-presenting cells recruited by Brugia malayi induce Th2 differentiation of naïve CD4(+) T cells. Eur J Immunol (2000) 1.33
Immunological focusing by th mouse major histocompatibility complex: mouse strains confronted with distantly related lysozymes confine their attention to very few epitopes. Eur J Immunol (1982) 1.29
APC from mice harbouring the filarial nematode, Brugia malayi, prevent cellular proliferation but not cytokine production. Int Immunol (1996) 1.28
Expression and immune recognition of Brugia malayi VAL-1, a homologue of vespid venom allergens and Ancylostoma secreted proteins. Mol Biochem Parasitol (2001) 1.26
Filarial-specific IgG4 response correlates with active Wuchereria bancrofti infection. J Immunol (1990) 1.26
Shared carbohydrate epitopes on distinct surface and secreted antigens of the parasitic nematode Toxocara canis. J Immunol (1987) 1.25
Assimilation of alkanes and alkenes by fungi. Appl Microbiol (1968) 1.24
Effects of nutritional and mechanical properties of food on ruminative behavior. J Exp Anal Behav (1985) 1.23
Adult and microfilarial stages of the filarial parasite Brugia malayi stimulate contrasting cytokine and Ig isotype responses in BALB/c mice. J Immunol (1994) 1.20
Nippostrongylus brasiliensis: cytokine responses and nematode expulsion in normal and IL-4-deficient mice. Exp Parasitol (1996) 1.20
Intussusception: evolution of current management. J Pediatr Gastroenterol Nutr (1988) 1.19
Serine proteinase inhibitors from nematodes and the arms race between host and pathogen. Trends Biochem Sci (2001) 1.19
The effect of catecholamines and prostaglandins upon human and rat erythrocytes. Biochim Biophys Acta (1975) 1.18
Multicentre laboratory evaluation of Brugia Rapid dipstick test for detection of brugian filariasis. Trop Med Int Health (2003) 1.18
Characterization of surface and excretory-secretory antigens of Toxocara canis infective larvae. Parasite Immunol (1984) 1.17
A novel member of the transforming growth factor-beta (TGF-beta) superfamily from the filarial nematodes Brugia malayi and B. pahangi. Exp Parasitol (1998) 1.16
Identification of abundantly expressed novel and conserved genes from the infective larval stage of Toxocara canis by an expressed sequence tag strategy. Infect Immun (1999) 1.15
T cell responsiveness correlates differentially with antibody isotype levels in clinical and asymptomatic filariasis. J Infect Dis (1993) 1.14
Immunology of human helminth infection. Int Arch Allergy Immunol (1996) 1.12
Depression of antigen-specific interleukin-5 and interferon-gamma responses in human lymphatic filariasis as a function of clinical status and age. J Infect Dis (1997) 1.11
An abundant, trans-spliced mRNA from Toxocara canis infective larvae encodes a 26-kDa protein with homology to phosphatidylethanolamine-binding proteins. J Biol Chem (1995) 1.10
Toxocara canis: a labile antigenic surface coat overlying the epicuticle of infective larvae. Exp Parasitol (1992) 1.09
Helminth C-type lectins and host-parasite interactions. Parasitol Today (2000) 1.09
Nematode surface coats: actively evading immunity. Parasitol Today (1992) 1.08
A novel serpin expressed by blood-borne microfilariae of the parasitic nematode Brugia malayi inhibits human neutrophil serine proteinases. Blood (1999) 1.08
Evidence of an autologous immune complex pathogenic mechanism in acute poststreptococcal glomerulonephritis. Kidney Int (1978) 1.07
Age-specific acquisition of immunity to infective larvae in a bancroftian filariasis endemic area of Papua New Guinea. Parasite Immunol (1991) 1.06
Evolution and immunology. The economics of immunity. Science (2000) 1.05
An abundantly expressed mucin-like protein from Toxocara canis infective larvae: the precursor of the larval surface coat glycoproteins. Proc Natl Acad Sci U S A (1996) 1.05
Differentially expressed, abundant trans-spliced cDNAs from larval Brugia malayi. Mol Biochem Parasitol (1997) 1.04
A novel C-type lectin secreted by a tissue-dwelling parasitic nematode. Curr Biol (1999) 1.04
Specificity of surface molecules of adult Brugia parasites: cross-reactivity with antibody from Wuchereria, Onchocerca and other human filarial infections. Trop Med Parasitol (1985) 1.04
Biochemical properties of larval excretory-secretory glycoproteins of the parasitic nematode Toxocara canis. Mol Biochem Parasitol (1986) 1.04
Differential decline in filaria-specific IgG1, IgG4, and IgE antibodies in Brugia malayi-infected patients after diethylcarbamazine chemotherapy. J Infect Dis (1995) 1.03
Gongylonema infection of the mouth in a resident of Cambridge, Massachusetts. Clin Infect Dis (2001) 1.03
Restricted sets of parasite antigens from the surface of different stages and sexes of the nematode parasite Nippostrongylus brasiliensis. Immunology (1983) 1.03
Acquired immune heterogeneity and its sources in human helminth infection. Parasitology (2010) 1.03
A family of secreted mucins from the parasitic nematode Toxocara canis bears diverse mucin domains but shares similar flanking six-cysteine repeat motifs. J Biol Chem (2000) 1.03
Interleukin-5 is essential for vaccine-mediated immunity but not innate resistance to a filarial parasite. Infect Immun (2000) 1.03
Immune specificity of murine T-cell lines to the major outer membrane protein of Chlamydia trachomatis. Infect Immun (1992) 1.02
Scheuermann's dorsal kyphosis and spinal cord compression: case report. Neurosurgery (1986) 1.01
Outpatient management of the severely ill child. A timed priority system. Am J Dis Child (1972) 1.01
Studies on the mechanism of action of aldosterone: hormone-induced changes in lipid metabolism. Biochemistry (1971) 1.00
Characterization of nematode glycoproteins: the major O-glycans of Toxocara excretory-secretory antigens are O-methylated trisaccharides. Glycobiology (1991) 1.00
The relative merits of various methods of indirect measurement of intraabdominal pressure as a guide to closure of abdominal wall defects. J Pediatr Surg (1987) 1.00
Requirement for in vivo production of IL-4, but not IL-10, in the induction of proliferative suppression by filarial parasites. J Immunol (1998) 0.99
Diagnosis of human toxocariasis by antigen capture enzyme linked immunosorbent assay. J Clin Pathol (1993) 0.98
The pathogenesis of hemorrhage in the lung of the hamster during acute leptospirosis. Med Microbiol Immunol (1974) 0.97
Molecules on the surface of parasitic nematodes as probes of the immune response in infection. Immunol Rev (1982) 0.97
The serpin secreted by Brugia malayi microfilariae, Bm-SPN-2, elicits strong, but short-lived, immune responses in mice and humans. J Immunol (2000) 0.97
Lipoblastoma: better termed infantile lipoma? Pediatr Surg Int (2000) 0.96
Repeated patent infection of adult dogs with Toxocara canis. J Helminthol (1984) 0.96
Phosphorylcholine-bearing antigens in filarial nematode parasites: analysis of somatic extracts, in-vitro secretions and infection sera from Brugia malayi and B. pahangi. Parasite Immunol (1987) 0.96
The umbilical polyp. J Pediatr Surg (1979) 0.96
Human red blood cells: prostaglandin E2, epinephrine, and isoproterenol alter deformability. Science (1971) 0.96
Microbial subterminal oxidation of alkanes and alk-1-enes. Lipids (1971) 0.96
Conditions for the development of IgM- and IgG-antibody-secreting cells from primed mouse splenocytes in vitro. Immunology (1977) 0.96
Antibody responses to filarial infective larvae are not dominated by the IgG4 isotype. Parasite Immunol (1998) 0.95
Identification, synthesis and immunogenicity of cuticular collagens from the filarial nematodes Brugia malayi and Brugia pahangi. Mol Biochem Parasitol (1989) 0.94
Species-specific and common epitopes on the secreted and surface antigens of Toxocara cati and Toxocara canis infective larvae. Parasite Immunol (1987) 0.94
Identification of a new C-type lectin, TES-70, secreted by infective larvae of Toxocara canis, which binds to host ligands. Parasitology (2000) 0.94
Heat shock cognate 70 is a prominent immunogen in Brugian filariasis. J Immunol (1989) 0.94
daf-7-related TGF-beta homologues from Trichostrongyloid nematodes show contrasting life-cycle expression patterns. Parasitology (2009) 0.93
Requirement for in vivo production of IL-4, but not IL-10, in the induction of proliferative suppression by filarial parasites. J Immunol (1998) 0.93
Impact of bicycle helmet safety legislation on children admitted to a regional pediatric trauma center. J Pediatr Surg (1998) 0.93
Cuticular localisation and turnover of the major surface glycoprotein (gp29) of adult Brugia malayi. Mol Biochem Parasitol (1990) 0.92
Parasite genetic diversity does not influence TNF-mediated effects on the virulence of primary rodent malaria infections. Parasitology (2006) 0.92
Adults acquire filarial infection more rapidly than children: a study in Indonesian transmigrants. Parasitology (2001) 0.91
Cluster health program for day care children. Am J Public Health (1975) 0.91
Ascaris suum-derived products induce human neutrophil activation via a G protein-coupled receptor that interacts with the interleukin-8 receptor pathway. Infect Immun (2001) 0.90
Secreted and circulating antigens of the filarial parasite Brugia pahangi: analysis of in vitro released components and detection of parasite products in vivo. Mol Biochem Parasitol (1985) 0.90