Published in Biochem Biophys Res Commun on July 30, 1997
Amylin proprotein processing generates progressively more amyloidogenic peptides that initially sample the helical state. Biochemistry (2008) 1.51
Misfolded proteins in Alzheimer's disease and type II diabetes. Chem Soc Rev (2011) 1.45
Pancreatic beta-cell granule peptides form heteromolecular complexes which inhibit islet amyloid polypeptide fibril formation. Biochem J (2004) 1.22
Role of zinc in human islet amyloid polypeptide aggregation. J Am Chem Soc (2010) 1.11
A novel assay in vitro of human islet amyloid polypeptide amyloidogenesis and effects of insulin secretory vesicle peptides on amyloid formation. Biochem J (1998) 1.09
Islet amyloid: from fundamental biophysics to mechanisms of cytotoxicity. FEBS Lett (2013) 1.08
Biphasic effects of insulin on islet amyloid polypeptide membrane disruption. Biophys J (2011) 0.97
Type 2 diabetes as a protein misfolding disease. Trends Mol Med (2015) 0.91
Amyloid deposition in transplanted human pancreatic islets: a conceivable cause of their long-term failure. Exp Diabetes Res (2009) 0.90
Transthyretin and amyloid in the islets of Langerhans in type-2 diabetes. Exp Diabetes Res (2008) 0.88
Amyloid in the islets of Langerhans: thoughts and some historical aspects. Ups J Med Sci (2011) 0.87
Defining the molecular basis of amyloid inhibitors: human islet amyloid polypeptide-insulin interactions. J Am Chem Soc (2014) 0.86
Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology. J Diabetes Res (2015) 0.83
Accumulation of intrahepatic islet amyloid in a nonhuman primate transplant model. Endocrinology (2012) 0.81
The role of the 14-20 domain of the islet amyloid polypeptide in amyloid formation. Exp Diabetes Res (2008) 0.81
Amyloid and transplanted islets. N Engl J Med (2008) 0.79
Molecular Structure, Membrane Interactions, and Toxicity of the Islet Amyloid Polypeptide in Type 2 Diabetes Mellitus. J Diabetes Res (2015) 0.76
The Effects of Lipid Membranes, Crowding and Osmolytes on the Aggregation, and Fibrillation Propensity of Human IAPP. J Diabetes Res (2015) 0.75
FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance. Cell (2001) 5.22
Enhancement of structural preservation and immunocytochemical staining in low temperature embedded pancreatic tissue. J Histochem Cytochem (1981) 4.62
Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus. N Engl J Med (1992) 4.37
Periplasmic gel: new concept resulting from the reinvestigation of bacterial cell envelope ultrastructure by new methods. J Bacteriol (1984) 3.33
Mammalian deoxyribonucleoside kinases. Pharmacol Ther (1995) 3.31
Myrosinase: gene family evolution and herbivore defense in Brassicaceae. Plant Mol Biol (2000) 3.15
Effect of omeprazole and ranitidine on ulcer healing and relapse rates in patients with benign gastric ulcer. N Engl J Med (1989) 3.03
Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy. Nat Genet (2001) 2.91
Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency. N Engl J Med (1986) 2.84
Collagenous colitis: a retrospective study of clinical presentation and treatment in 163 patients. Gut (1996) 2.79
Studies in alpha 1-antitrypsin deficiency. Acta Med Scand Suppl (1965) 2.77
The deoxyguanosine kinase gene is mutated in individuals with depleted hepatocerebral mitochondrial DNA. Nat Genet (2001) 2.71
A randomized trial of risperidone, placebo, and haloperidol for behavioral symptoms of dementia. Neurology (1999) 2.51
Microscopic colitis: a common diarrhoeal disease. An epidemiological study in Orebro, Sweden, 1993-1998. Gut (2004) 2.48
Cell cycle-dependent expression of mammalian ribonucleotide reductase. Differential regulation of the two subunits. J Biol Chem (1985) 2.47
Frequency of antibiotic-associated diarrhoea in 2462 antibiotic-treated hospitalized patients: a prospective study. J Antimicrob Chemother (2001) 2.35
Specimen preparation for electron microscopy using low temperature embedding resins. J Microsc (1982) 2.33
Collagenous colitis and fecal stream diversion. Gastroenterology (1995) 2.32
Oral immunoglobulin A supplement in treatment of Clostridium difficile enteritis. Lancet (1993) 2.22
Cell cycle-dependent regulation of mammalian ribonucleotide reductase. The S phase-correlated increase in subunit M2 is regulated by de novo protein synthesis. J Biol Chem (1984) 2.19
Diverging substrate specificity of pure human thymidine kinases 1 and 2 against antiviral dideoxynucleosides. J Biol Chem (1991) 2.19
Bacterial genome size reduction by experimental evolution. Proc Natl Acad Sci U S A (2005) 2.13
Islet amyloid and type 2 diabetes mellitus. N Engl J Med (2000) 2.07
Restriction and enhancement of human immunodeficiency virus type 1 replication by modulation of intracellular deoxynucleoside triphosphate pools. J Virol (1994) 2.07
Fifty-two-week efficacy and safety of vildagliptin vs. glimepiride in patients with type 2 diabetes mellitus inadequately controlled on metformin monotherapy. Diabetes Obes Metab (2009) 2.04
Nasal continuous positive airway pressure in stroke patients with sleep apnoea: a randomized treatment study. Eur Respir J (2001) 1.97
The liver in adolescents with alpha 1-antitrypsin deficiency. Hepatology (1995) 1.95
Ribonucleotide reductase from calf thymus. Purification and properties. Biochemistry (1979) 1.90
Trapped antihydrogen. Nature (2010) 1.85
Systematic review: microscopic colitis. Aliment Pharmacol Ther (2006) 1.81
Ribonucleotide reductase from calf thymus. Separation of the enzyme into two nonidentical subunits, proteins M1 and M2. J Biol Chem (1980) 1.78
Allosteric regulation of calf thymus ribonucleoside diphosphate reductase. Biochemistry (1979) 1.76
Serum calcium and survival in a large health screening program. J Clin Endocrinol Metab (1996) 1.76
Liver disease in adults with alpha-1 -antitrypsin deficiency. N Engl J Med (1972) 1.75
Randomized clinical trial of the effect of interferon alpha on survival in patients with disseminated midgut carcinoid tumours. Br J Surg (2003) 1.74
Endothelial cells are a site of uptake and degradation of hyaluronic acid in the liver. Exp Cell Res (1983) 1.74
Adrenal incidentaloma--experience of a standardized diagnostic programme in the Swedish prospective study. J Intern Med (2002) 1.74
Collagenous colitis in Orebro, Sweden, an epidemiological study 1984-1993. Gut (1995) 1.64
Familial occurrence of microscopic colitis: a report on five families. Scand J Gastroenterol (2001) 1.64
The comet assay: mechanisms and technical considerations. Mutat Res (1996) 1.62
Biochemical effect of liver transplantation in two Swedish patients with familial amyloidotic polyneuropathy (FAP-met30). Clin Genet (1991) 1.60
Blunted adrenocorticotropin and increased adrenal steroid response to human corticotropin-releasing hormone in Alzheimer's disease. Biol Psychiatry (1996) 1.56
Carcinoma and possible precancerous changes of the gastric stump after billroth II resection. Gastroenterology (1977) 1.56
Lymphocytic colitis: a retrospective clinical study of 199 Swedish patients. Gut (2004) 1.56
Aetiological aspects on primary liver cancer with special regard to alcohol, organic solvents and acute intermittent porphyria--an epidemiological investigation. Br J Cancer (1984) 1.56
Liver, lung and malignant disease in heterozygous (Pi MZ) alpha1-antitrypsin deficiency. Acta Med Scand (1975) 1.55
Islet dysfunction in insulin resistance involves impaired insulin secretion and increased glucagon secretion in postmenopausal women with impaired glucose tolerance. Diabetes Care (2000) 1.54
Leptin is associated with increased risk of myocardial infarction. J Intern Med (1999) 1.52
Ribonucleoside diphosphate reductase from Escherichia coli. An immunological assay and a novel purification from an overproducing strain lysogenic for phage lambdadnrd. J Biol Chem (1977) 1.52
Alpha cell function in health and disease: influence of glucagon-like peptide-1. Diabetologia (2005) 1.51
Studies in vitro on the uptake and degradation of sodium hyaluronate in rat liver endothelial cells. Biochem J (1984) 1.50
Neuropeptidergic versus cholinergic and adrenergic regulation of islet hormone secretion. Diabetologia (1986) 1.49
Ribonucleoside diphosphate reductase (Escherichia coli). Methods Enzymol (1978) 1.49
Dipeptidyl peptidase-4 inhibitors and cardiovascular risk: a meta-analysis of randomized clinical trials. Diabetes Obes Metab (2012) 1.49
Incidence and clinical characterization of unprovoked seizures in adults: a prospective population-based study. Epilepsia (1996) 1.47
Escherichia coli induces transuroepithelial neutrophil migration by an intercellular adhesion molecule-1-dependent mechanism. Infect Immun (1995) 1.47
Obstructive lung disease and trypsin inhibitors in alpha-1-antitrypsin deficiency. Scand J Clin Lab Invest (1967) 1.46
Deoxycytidine kinase is constitutively expressed in human lymphocytes: consequences for compartmentation effects, unscheduled DNA synthesis, and viral replication in resting cells. Exp Cell Res (1988) 1.45
Hepatocyte inclusions of alpha 1-antichymotrypsin in a patient with partial deficiency of alpha 1-antichymotrypsin and chronic liver disease. Histopathology (1990) 1.44
Hepatitis C in chronic liver disease: an epidemiological study based on 566 consecutive patients undergoing liver biopsy during a 10-year period. J Intern Med (1992) 1.44
Effect of omeprazole on the outcome of endoscopically treated bleeding peptic ulcers. Randomized double-blind placebo-controlled multicentre study. Scand J Gastroenterol (1997) 1.44
A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in individuals with ischaemic heart disease. Diabetologia (2007) 1.42
Acrylamide: a cooking carcinogen? Chem Res Toxicol (2000) 1.40
Low temperature embedding with Lowicryl resins: two new formulations and some applications. J Microsc (1985) 1.39
Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men. Diabetes Care (2001) 1.38
[The influence of bear acid on lipid metabolism. A future drug?]. Lakartidningen (1995) 1.38
A non-intensive stroke unit reduces functional disability and the need for long-term hospitalization. Stroke (1985) 1.37
[More accurate diagnosis could identify patients suitable for tacrine therapy]. Lakartidningen (1996) 1.37
Short-term dexamethasone treatment increases plasma leptin independently of changes in insulin sensitivity in healthy women. J Clin Endocrinol Metab (1996) 1.37
Intracellular metabolism of 3'-azidothymidine in isolated human peripheral blood mononuclear cells. AIDS Res Hum Retroviruses (1991) 1.37
Continuous intravenous infusion of omeprazole in elderly patients with peptic ulcer bleeding. Results of a placebo-controlled multicenter study. Scand J Gastroenterol (1997) 1.36
Characterization of alpha1-antitrypsin in the inclusion bodies from the liver in alpha 1-antitrypsin deficiency. N Engl J Med (1975) 1.35
Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice. Am J Physiol Endocrinol Metab (2001) 1.34
Human thymidine kinase 2: molecular cloning and characterisation of the enzyme activity with antiviral and cytostatic nucleoside substrates. FEBS Lett (1999) 1.34
Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model. Diabetologia (1999) 1.34
Effect of age and occupational exposure to airway irritants on lung function in non-smoking individuals with alpha 1-antitrypsin deficiency (PiZZ). Thorax (1997) 1.33
Resonant quantum transitions in trapped antihydrogen atoms. Nature (2012) 1.32
Glycaemic efficacy of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors as add-on therapy to metformin in subjects with type 2 diabetes-a review and meta analysis. Diabetes Obes Metab (2012) 1.30
Apoptosis of renal cortical cells in the hemolytic-uremic syndrome: in vivo and in vitro studies. Infect Immun (1998) 1.27
Infection by Helicobacter pylori expressing the BabA adhesin is influenced by the secretor phenotype. J Pathol (2008) 1.26
Autonomic mediation of glucagon secretion during hypoglycemia: implications for impaired alpha-cell responses in type 1 diabetes. Diabetes (1998) 1.25
Late precancerous changes and carcinoma of the gastric stump after Billroth I resection. Am J Surg (1976) 1.25
Description and first application of a new technique to measure the gravitational mass of antihydrogen. Nat Commun (2013) 1.25
Extraction of membrane lipids during fixation, dehydration and embedding of Acholeplasma laidlawii-cells for electron microscopy. J Microsc (1983) 1.24
Purification and partial characterization of pas-positive inclusion bodies from the liver in alpha 1-antitrypsin deficiency. N Engl J Med (1975) 1.23
Marked and rapid decreases of circulating leptin in streptozotocin diabetic rats: reversal by insulin. Am J Physiol (1998) 1.22
Glutathione-dependent hydrogen donor system for calf thymus ribonucleoside-diphosphate reductase. Proc Natl Acad Sci U S A (1979) 1.21
PAC1 receptor-deficient mice display impaired insulinotropic response to glucose and reduced glucose tolerance. J Clin Invest (2000) 1.19
A controlled multicenter clinical study of citalopram and placebo in elderly depressed patients with and without concomitant dementia. Acta Psychiatr Scand (1992) 1.18
alpha-Actinin promotes polymerization of actin from profilactin. Eur J Biochem (1980) 1.18
Decline in FEV1 related to smoking status in individuals with severe alpha1-antitrypsin deficiency (PiZZ). Eur Respir J (1999) 1.18
Biochemical pharmacology and resistance to 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, a novel analogue of cladribine in human leukemic cells. Clin Cancer Res (1999) 1.18
Purification and characterization of cytoplasmic thioltransferase (glutathione:disulfide oxidoreductase) from rat liver. Biochemistry (1978) 1.18
Glucagon receptor antagonism improves islet function in mice with insulin resistance induced by a high-fat diet. Diabetologia (2007) 1.17
Infectious pancreatic necrosis virus: identification of a VP3-containing ribonucleoprotein core structure and evidence for O-linked glycosylation of the capsid protein VP2. J Virol (1999) 1.16
Heteromeric interactions among nucleoid-associated bacterial proteins: localization of StpA-stabilizing regions in H-NS of Escherichia coli. J Bacteriol (2001) 1.16
Cirrhosis and malignant hepatoma in alpha 1-antitrypsin deficiency. Acta Med Scand (1974) 1.15
Capsule of Escherichia coli K29: ultrastructural preservation and immunoelectron microscopy. J Bacteriol (1985) 1.14
Stereoselective interaction of omeprazole with warfarin in healthy men. Ther Drug Monit (1989) 1.13