Published in Nat Biotechnol on August 01, 1997
Stabilization of a beta-hairpin in monomeric Alzheimer's amyloid-beta peptide inhibits amyloid formation. Proc Natl Acad Sci U S A (2008) 1.99
Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently. Chem Soc Rev (2015) 1.74
Structural basis for recognition by an in vitro evolved affibody. Proc Natl Acad Sci U S A (2003) 1.46
Two-state selection of conformation-specific antibodies. Proc Natl Acad Sci U S A (2009) 1.40
An affibody in complex with a target protein: structure and coupled folding. Proc Natl Acad Sci U S A (2003) 1.35
A new generation of protein display scaffolds for molecular recognition. Protein Sci (2006) 1.29
Teaching an old scaffold new tricks: monobodies constructed using alternative surfaces of the FN3 scaffold. J Mol Biol (2011) 1.29
Extending half-life by indirect targeting of the neonatal Fc receptor (FcRn) using a minimal albumin binding domain. J Biol Chem (2010) 1.27
Structural basis for high-affinity HER2 receptor binding by an engineered protein. Proc Natl Acad Sci U S A (2010) 1.24
Structural insights for engineering binding proteins based on non-antibody scaffolds. Curr Opin Struct Biol (2012) 1.18
Tropism-modification strategies for targeted gene delivery using adenoviral vectors. Viruses (2010) 1.17
Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein. J Mol Biol (2008) 1.14
A rapid and scalable method for selecting recombinant mouse monoclonal antibodies. BMC Biol (2010) 1.13
HER2- and EGFR-specific affiprobes: novel recombinant optical probes for cell imaging. Chembiochem (2010) 1.10
Direct site-specific radiolabeling of an Affibody protein with 4-[18F]fluorobenzaldehyde via oxime chemistry. Mol Imaging Biol (2008) 1.08
Targeting HER2-positive cancer cells with receptor-redirected anthrax protective antigen. Mol Oncol (2012) 1.07
Development of GFP-based biosensors possessing the binding properties of antibodies. Proc Natl Acad Sci U S A (2009) 1.06
Imaging of HER2-expressing tumours using a synthetic Affibody molecule containing the 99mTc-chelating mercaptoacetyl-glycyl-glycyl-glycyl (MAG3) sequence. Eur J Nucl Med Mol Imaging (2006) 1.06
Generation and characterization of monoclonal antibodies against dengue virus type 1 for epitope mapping and serological detection by epitope-based peptide antigens. Clin Vaccine Immunol (2007) 1.04
Adenoviral vector-based strategies for cancer therapy. Curr Drug ther (2009) 1.02
Phage-displayed peptide libraries. Curr Opin Biotechnol (1998) 1.02
Affibody-mediated tumour targeting of HER-2 expressing xenografts in mice. Eur J Nucl Med Mol Imaging (2006) 1.02
99mTc-chelator engineering to improve tumour targeting properties of a HER2-specific Affibody molecule. Eur J Nucl Med Mol Imaging (2007) 1.02
Eliminating helper phage from phage display. Nucleic Acids Res (2006) 0.99
Toward next generation plasma profiling via heat-induced epitope retrieval and array-based assays. Mol Cell Proteomics (2010) 0.99
Characterization of neutralizing antibodies and identification of neutralizing epitope mimics on the Clostridium botulinum neurotoxin type A. Appl Environ Microbiol (2001) 0.98
Adenovirus receptors and their implications in gene delivery. Virus Res (2009) 0.98
Mutational analysis of the interaction between albumin-binding domain from streptococcal protein G and human serum albumin. Protein Sci (2002) 0.97
Nanobodies and recombinant binders in cell biology. J Cell Biol (2015) 0.96
Antibody binding loop insertions as diversity elements. Nucleic Acids Res (2006) 0.95
Staphylococcal surface display of metal-binding polyhistidyl peptides. Appl Environ Microbiol (2000) 0.95
Modification of adenovirus capsid with a designed protein ligand yields a gene vector targeted to a major molecular marker of cancer. J Virol (2007) 0.94
Using in-vivo fluorescence imaging in personalized cancer diagnostics and therapy, an image and treat paradigm. Technol Cancer Res Treat (2011) 0.93
Detection of biomarkers using recombinant antibodies coupled to nanostructured platforms. Nano Rev (2012) 0.93
Targeting diverse protein-protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold. Proc Natl Acad Sci U S A (2015) 0.93
Illuminating the life of GPCRs. Cell Commun Signal (2009) 0.92
Cellular effects of HER3-specific affibody molecules. PLoS One (2012) 0.91
Recombinant amyloid beta-peptide production by coexpression with an affibody ligand. BMC Biotechnol (2008) 0.90
The Proteomic Code: a molecular recognition code for proteins. Theor Biol Med Model (2007) 0.90
LOVTRAP: an optogenetic system for photoinduced protein dissociation. Nat Methods (2016) 0.90
Molecular imaging of EGFR/HER2 cancer biomarkers by protein MRI contrast agents. J Biol Inorg Chem (2013) 0.88
Radiolabeled affibody-albumin bioconjugates for HER2-positive cancer targeting. Bioconjug Chem (2011) 0.88
Critical ligand binding reagent preparation/selection: when specificity depends on reagents. AAPS J (2007) 0.88
HER2-affitoxin: a potent therapeutic agent for the treatment of HER2-overexpressing tumors. Clin Cancer Res (2011) 0.88
Developmental validation of short tandem repeat reagent kit for forensic DNA profiling of canine biological material. Croat Med J (2009) 0.87
Human interleukin-23 receptor antagonists derived from an albumin-binding domain scaffold inhibit IL-23-dependent ex vivo expansion of IL-17-producing T-cells. Proteins (2013) 0.86
Evaluation of staphylococcal cell surface display and flow cytometry for postselectional characterization of affinity proteins in combinatorial protein engineering applications. Appl Environ Microbiol (2007) 0.86
Influence of valency and labelling chemistry on in vivo targeting using radioiodinated HER2-binding Affibody molecules. Eur J Nucl Med Mol Imaging (2008) 0.86
In vitro and in vivo assessment of targeting lipid-based nanoparticles to the epidermal growth factor-receptor (EGFR) using a novel Heptameric ZEGFR domain. J Control Release (2011) 0.85
Engineered lactic acid bacterium Lactococcus lactis capable of binding antibodies and tumor necrosis factor alpha. Appl Environ Microbiol (2010) 0.85
Affibody-DyLight conjugates for in vivo assessment of HER2 expression by near-infrared optical imaging. PLoS One (2012) 0.84
Peptide-mediated liposomal drug delivery system targeting tumor blood vessels in anticancer therapy. J Oncol (2010) 0.84
Unraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based Therapeutics. Front Immunol (2015) 0.84
TEM-1 beta-lactamase as a scaffold for protein recognition and assay. Protein Sci (2002) 0.83
A transductionally retargeted adenoviral vector for virotherapy of Her2/neu-expressing prostate cancer. Hum Gene Ther (2011) 0.83
(186)Re-maSGS-Z (HER2:342), a potential Affibody conjugate for systemic therapy of HER2-expressing tumours. Eur J Nucl Med Mol Imaging (2009) 0.83
Molecular imaging of insulin-like growth factor 1 receptor in cancer. Am J Nucl Med Mol Imaging (2012) 0.83
Combinatorial surrobody libraries. Proc Natl Acad Sci U S A (2008) 0.81
Protein-based tumor molecular imaging probes. Amino Acids (2010) 0.81
Biophysical characterization of Z(SPA-1)--a phage-display selected binder to protein A. Protein Sci (2004) 0.81
Generation of metal-binding staphylococci through surface display of combinatorially engineered cellulose-binding domains. Appl Environ Microbiol (2001) 0.80
New binding mode to TNF-alpha revealed by ubiquitin-based artificial binding protein. PLoS One (2012) 0.80
N-terminal engineering of amyloid-β-binding Affibody molecules yields improved chemical synthesis and higher binding affinity. Protein Sci (2010) 0.80
Peptide aptamers: development and applications. Curr Top Med Chem (2015) 0.80
Tracking molecular recognition at the atomic level with a new protein scaffold based on the OB-fold. PLoS One (2014) 0.80
iBodies: Modular Synthetic Antibody Mimetics Based on Hydrophilic Polymers Decorated with Functional Moieties. Angew Chem Int Ed Engl (2016) 0.79
Directed evolution of anti-HER2 DARPins by SNAP display reveals stability/function trade-offs in the selection process. Protein Eng Des Sel (2015) 0.79
Ribosome display selection of a murine IgG₁ Fab binding affibody molecule allowing species selective recovery of monoclonal antibodies. Mol Biotechnol (2011) 0.79
Good manufacturing practice production of [(68)Ga]Ga-ABY-025 for HER2 specific breast cancer imaging. Am J Nucl Med Mol Imaging (2016) 0.79
NextGen protein design. Biochem Soc Trans (2013) 0.78
177Lu-DO3A-HSA-Z EGFR:1907: characterization as a potential radiopharmaceutical for radionuclide therapy of EGFR-expressing head and neck carcinomas. J Biol Inorg Chem (2012) 0.78
An engineered affibody molecule with pH-dependent binding to FcRn mediates extended circulatory half-life of a fusion protein. Proc Natl Acad Sci U S A (2014) 0.78
Engineering of a human kringle domain into agonistic and antagonistic binding proteins functioning in vitro and in vivo. Proc Natl Acad Sci U S A (2010) 0.78
Staphylococcal surface display of immunoglobulin A (IgA)- and IgE-specific in vitro-selected binding proteins (affibodies) based on Staphylococcus aureus protein A. Appl Environ Microbiol (1999) 0.78
Improved cancer therapy and molecular imaging with multivalent, multispecific antibodies. Cancer Biother Radiopharm (2010) 0.77
Fluorescence-activated cell sorting of specific affibody-displaying staphylococci. Appl Environ Microbiol (2003) 0.77
An affibody-adalimumab hybrid blocks combined IL-6 and TNF-triggered serum amyloid A secretion in vivo. MAbs (2014) 0.77
Molecular imaging of hepatocellular carcinoma xenografts with epidermal growth factor receptor targeted affibody probes. Biomed Res Int (2013) 0.77
Tethered protein display identifies a novel Kir3.2 (GIRK2) regulator from protein scaffold libraries. ACS Chem Neurosci (2014) 0.76
An engineered autotransporter-based surface expression vector enables efficient display of Affibody molecules on OmpT-negative E. coli as well as protease-mediated secretion in OmpT-positive strains. Microb Cell Fact (2014) 0.76
Antibody-based imaging of HER-2: moving into the clinic. Curr Mol Med (2013) 0.76
Engineering tandem single-chain Fv as cell surface reporters with enhanced properties of fluorescence detection. Protein Eng Des Sel (2015) 0.75
Beyond Antibodies: Development of a Novel Protein Scaffold Based on Human Chaperonin 10. Sci Rep (2016) 0.75
Intra-domain phage display (ID-PhD) of peptides and protein mini-domains censored from canonical pIII phage display. Front Microbiol (2015) 0.75
Preclinical PET imaging of EGFR levels: pairing a targeting with a non-targeting Sel-tagged Affibody-based tracer to estimate the specific uptake. EJNMMI Res (2016) 0.75
Iterative non-proteinogenic residue incorporation yields α/β-peptides with a helix-loop-helix tertiary structure and high affinity for VEGF. Chembiochem (2016) 0.75
Extremophilic 50S Ribosomal RNA-Binding Protein L35Ae as a Basis for Engineering of an Alternative Protein Scaffold. PLoS One (2015) 0.75
Affibody molecules as engineered protein drugs. Exp Mol Med (2017) 0.75
Tetraspecific ligand for tumor-targeted delivery of nanomaterials. Biomaterials (2014) 0.75
Generation of affibody molecules specific for HPV16 E7 recognition. Oncotarget (2016) 0.75
In vivo evaluation of a novel format of a bivalent HER3-targeting and albumin-binding therapeutic affibody construct. Sci Rep (2017) 0.75
A current perspective on applications of macrocyclic-peptide-based high-affinity ligands. Biopolymers (2016) 0.75
Monobodies and other synthetic binding proteins for expanding protein science. Protein Sci (2017) 0.75
A Conjugate Based on Anti-HER2 Diaffibody and Auristatin E Targets HER2-Positive Cancer Cells. Int J Mol Sci (2017) 0.75
Emerging Affinity-Based Proteomic Technologies for Large-Scale Plasma Profiling in Cardiovascular Disease. Circulation (2017) 0.75
A sequencing method based on real-time pyrophosphate. Science (1998) 21.21
Real-time DNA sequencing using detection of pyrophosphate release. Anal Biochem (1996) 12.94
Direct solid phase sequencing of genomic and plasmid DNA using magnetic beads as solid support. Nucleic Acids Res (1989) 9.04
Solid phase DNA minisequencing by an enzymatic luminometric inorganic pyrophosphate detection assay. Anal Biochem (1993) 7.71
Complete sequence of the staphylococcal gene encoding protein A. A gene evolved through multiple duplications. J Biol Chem (1984) 5.94
A high frequency of sequence alterations is due to formalin fixation of archival specimens. Am J Pathol (1999) 4.43
Gene discovery in the wood-forming tissues of poplar: analysis of 5, 692 expressed sequence tags. Proc Natl Acad Sci U S A (1998) 3.31
A synthetic IgG-binding domain based on staphylococcal protein A. Protein Eng (1989) 3.31
Single-nucleotide polymorphism analysis by pyrosequencing. Anal Biochem (2000) 3.21
Use of automated sequencing of polymerase chain reaction-generated amplicons to identify three types of cholera toxin subunit B in Vibrio cholerae O1 strains. J Clin Microbiol (1993) 3.01
Region X, the cell-wall-attachment part of staphylococcal protein A. Eur J Biochem (1984) 3.00
Gene for staphylococcal protein A. Proc Natl Acad Sci U S A (1983) 2.97
Immobilization and purification of enzymes with staphylococcal protein A gene fusion vectors. EMBO J (1985) 2.91
A transcriptional roadmap to wood formation. Proc Natl Acad Sci U S A (2001) 2.85
Identification of the causative agent of granulocytic ehrlichiosis in Swedish dogs and horses by direct solid phase sequencing of PCR products from the 16S rRNA gene. Res Vet Sci (1995) 2.77
Bidirectional solid-phase sequencing of in vitro-amplified plasmid DNA. Biotechniques (1991) 2.69
An improved positive selection plasmid vector constructed by oligonucleotide mediated mutagenesis. Nucleic Acids Res (1983) 2.69
Analysis of heterogeneous viral populations by direct DNA sequencing. Biotechniques (1993) 2.65
Accurate reconstruction of a known HIV-1 transmission history by phylogenetic tree analysis. Proc Natl Acad Sci U S A (1996) 2.57
Comparison of variable region 3 sequences of human immunodeficiency virus type 1 from infected children with the RNA and DNA sequences of the virus populations of their mothers. Proc Natl Acad Sci U S A (1993) 2.49
Magnetic separation techniques in diagnostic microbiology. Clin Microbiol Rev (1994) 2.41
A novel fusion gene, SYT-SSX4, in synovial sarcoma. J Natl Cancer Inst (1999) 2.36
Structure of the IgG-binding regions of streptococcal protein G. EMBO J (1986) 2.20
Biological and molecular characterization of subtype D, G, and A/D recombinant HIV-1 transmissions in Sweden. Virology (1995) 2.07
Specific binding of proinsulin C-peptide to human cell membranes. Proc Natl Acad Sci U S A (1999) 1.91
Analysis of a rape case by direct sequencing of the human immunodeficiency virus type 1 pol and gag genes. J Virol (1994) 1.88
Crystal structure of the C2 fragment of streptococcal protein G in complex with the Fc domain of human IgG. Structure (1995) 1.86
Affibody molecules: engineered proteins for therapeutic, diagnostic and biotechnological applications. FEBS Lett (2010) 1.85
Affinity fusion strategies for detection, purification, and immobilization of recombinant proteins. Protein Expr Purif (1997) 1.84
Sequence analysis of 16S rRNA from mycoplasmas by direct solid-phase DNA sequencing. Appl Environ Microbiol (1994) 1.81
Analysis of signals for secretion in the staphylococcal protein A gene. EMBO J (1985) 1.72
Uniformly spaced banding pattern in DNA sequencing gels by use of field-strength gradient. J Biochem Biophys Methods (1984) 1.71
Direct solid-phase sequence analysis of the human p53 gene by use of multiplex polymerase chain reaction and alpha-thiotriphosphate nucleotides. Clin Chem (1995) 1.67
Phylogeny of some mycoplasmas from ruminants based on 16S rRNA sequences and definition of a new cluster within the hominis group. Int J Syst Bacteriol (1996) 1.64
Overexpression of podocalyxin-like protein is an independent factor of poor prognosis in colorectal cancer. Br J Cancer (2011) 1.64
Cloning, sequencing and expression of subtilisin Carlsberg from Bacillus licheniformis. Nucleic Acids Res (1985) 1.61
Gene fusion vectors based on the gene for staphylococcal protein A. Gene (1983) 1.61
Expression of the gene encoding protein A in Staphylococcus aureus and coagulase-negative staphylococci. J Bacteriol (1984) 1.61
Staphylococcal protein A consists of five IgG-binding domains. Eur J Biochem (1986) 1.56
Gene fusions for purpose of expression: an introduction. Methods Enzymol (1990) 1.52
Bacterial surface display: trends and progress. Trends Biotechnol (1997) 1.45
Solid phase DNA sequencing using the biotin-avidin system. Nucleic Acids Res (1988) 1.45
Engineering proteins to facilitate bioprocessing. Trends Biotechnol (1994) 1.43
General colorimetric method for DNA diagnostics allowing direct solid-phase genomic sequencing of the positive samples. Proc Natl Acad Sci U S A (1990) 1.43
A gene fusion system for generating antibodies against short peptides. Gene (1987) 1.42
Dynamic changes in HIV-1 quasispecies from azidothymidine (AZT)-treated patients. FASEB J (1992) 1.41
Human epidermal cancer and accompanying precursors have identical p53 mutations different from p53 mutations in adjacent areas of clonally expanded non-neoplastic keratinocytes. Oncogene (1996) 1.40
Persistence of azidothymidine-resistant human immunodeficiency virus type 1 RNA genotypes in posttreatment sera. J Virol (1992) 1.39
Analysis of the V3 loop in neutralization-resistant human immunodeficiency virus type 1 variants by direct solid-phase DNA sequencing. AIDS Res Hum Retroviruses (1991) 1.39
Analysis and use of the serum albumin binding domains of streptococcal protein G. J Mol Recognit (1988) 1.38
Phylogeny of the family Moraxellaceae by 16S rDNA sequence analysis, with special emphasis on differentiation of Moraxella species. Int J Syst Bacteriol (1998) 1.35
Limited genetic diversity of Plasmodium falciparum in field isolates from Honduras. Am J Trop Med Hyg (1999) 1.34
Selection and characterization of HER2/neu-binding affibody ligands. Protein Eng Des Sel (2004) 1.33
Chimeric IgG-binding receptors engineered from staphylococcal protein A and streptococcal protein G. J Biol Chem (1988) 1.33
Optimization of electroporation-mediated transformation: Staphylococcus carnosus as model organism. J Appl Microbiol (2007) 1.32
PATCHED and p53 gene alterations in sporadic and hereditary basal cell cancer. Oncogene (2001) 1.31
All individual domains of staphylococcal protein A show Fab binding. FEMS Immunol Med Microbiol (1998) 1.29
Structure and evolution of the repetitive gene encoding streptococcal protein G. Eur J Biochem (1987) 1.27
Analysis of oligonucleotide probe affinities using surface plasmon resonance: a means for mutational scanning. Anal Biochem (1997) 1.24
Molecular pathology in basal cell cancer with p53 as a genetic marker. Oncogene (1997) 1.24
A combinatorial library of an alpha-helical bacterial receptor domain. Protein Eng (1995) 1.23
Scaffolds for engineering novel binding sites in proteins. Curr Opin Struct Biol (1997) 1.23
Benign clonal keratinocyte patches with p53 mutations show no genetic link to synchronous squamous cell precancer or cancer in human skin. Am J Pathol (1997) 1.23
Variations in the cytomegalovirus major immediate-early gene found by direct genomic sequencing. J Clin Microbiol (1992) 1.22
Mutational analysis of the interaction between staphylococcal protein A and human IgG1. Protein Eng (1993) 1.22
Cell surface display of recombinant proteins on Staphylococcus carnosus. J Bacteriol (1995) 1.20
Molecular evolution of Mycoplasma capricolum subsp. capripneumoniae strains, based on polymorphisms in the 16S rRNA genes. J Bacteriol (1998) 1.20
Genomic analysis of single cells from human basal cell cancer using laser-assisted capture microscopy. Mutat Res (1997) 1.19
Cyclin A-cdc2 kinase does not trigger but delays cyclin degradation in interphase extracts of amphibian eggs. J Cell Sci (1992) 1.19
Surface display of a functional single-chain Fv antibody on staphylococci. J Bacteriol (1996) 1.19
Capture of single-stranded DNA assisted by oligonucleotide modules. Anal Biochem (1998) 1.18
Interaction between heat shock protein DnaK and recombinant staphylococcal protein A. J Bacteriol (1990) 1.18
Expression of recombinant proteins on the surface of the coagulase-negative bacterium Staphylococcus xylosus. J Bacteriol (1992) 1.18
Sequence-based analysis of the human p53 gene based on microdissection of tumor biopsy samples. Biotechniques (1994) 1.17
Characterization of a spotted fever group Rickettsia from Ixodes ricinus ticks in Sweden. J Clin Microbiol (1997) 1.17
The SYT-SSX1 variant of synovial sarcoma is associated with a high rate of tumor cell proliferation and poor clinical outcome. Cancer Res (1999) 1.16
Membranous expression of podocalyxin-like protein is an independent factor of poor prognosis in urothelial bladder cancer. Br J Cancer (2013) 1.16
Immunomagnetic purification to facilitate DNA diagnosis of Plasmodium falciparum. J Clin Microbiol (1993) 1.14
Induction of protective immunity in rodents by vaccination with a prokaryotically expressed recombinant fusion protein containing a respiratory syncytial virus G protein fragment. Virology (1997) 1.14
Analysis of the p53 tumor suppressor gene by pyrosequencing. Biotechniques (2000) 1.14
Persistent p53 mutations in single cells from normal human skin. Am J Pathol (2001) 1.14
Phage display selection of Affibody molecules with specific binding to the extracellular domain of the epidermal growth factor receptor. Protein Eng Des Sel (2007) 1.13
Rapid colorimetric detection of in vitro amplified DNA sequences. DNA Cell Biol (1990) 1.13
Sequencing and heterologous expression of the gene encoding penicillin V amidase from Bacillus sphaericus. Gene (1986) 1.12
Human protein atlas and the use of microarray technologies. Curr Opin Biotechnol (2008) 1.12
A cohort study of the prognostic and treatment predictive value of SATB2 expression in colorectal cancer. Br J Cancer (2012) 1.11
Phylogenetic analysis of rabbit haemorrhagic disease and European brown hare syndrome viruses by comparison of sequences from the capsid protein gene. Arch Virol (1997) 1.11
Kinetic analysis of the interaction between protein A domain variants and human Fc using plasmon resonance detection. J Mol Recognit (1996) 1.10