Published in Surgery on August 01, 1997
Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA-1A Sepsis Study Group. N Engl J Med (1991) 9.99
Are low tidal volumes safe? Chest (1990) 2.26
Ringer's ethyl pyruvate solution ameliorates ischemia/reperfusion-induced intestinal mucosal injury in rats. Crit Care Med (2001) 2.12
Tissue capnometry as a monitoring strategy for critically ill patients: just about ready for prime time. Chest (1998) 2.04
Gastric tonometry and venous oximetry in cardiac surgery patients. Crit Care Med (1991) 1.94
Cytokine-induced intestinal epithelial hyperpermeability: role of nitric oxide. Crit Care Med (1999) 1.81
Acidic conditions exacerbate interferon-gamma-induced intestinal epithelial hyperpermeability: role of peroxynitrous acid. Crit Care Med (1999) 1.69
Inhibition of inducible nitric oxide synthase ameliorates endotoxin-induced gut mucosal barrier dysfunction in rats. Gastroenterology (1997) 1.67
Hormonal responses to graded surgical stress. Arch Intern Med (1987) 1.59
Use of ultrahigh frequency ventilation in patients with ARDS. A preliminary report. Chest (1993) 1.45
Nitric oxide donors increase cytosolic ionized calcium in cultured human intestinal epithelial cells. Shock (1996) 1.40
CT grading of splenic trauma in adults: how the same statistics can be interpreted differently. Radiology (1991) 1.39
Another negative clinical trial of a new agent for the treatment of sepsis: rethinking the process of developing adjuvant treatments for serious infections. Crit Care Med (1995) 1.37
Secondary infection of post-traumatic pulmonary cavitary lesions in adolescents and young adults: role of computed tomography and operative debridement and drainage. J Trauma (1989) 1.37
Gram-negative bacteremia produces both severe systolic and diastolic cardiac dysfunction in a canine model that simulates human septic shock. J Clin Invest (1986) 1.34
Left ventricular systolic and diastolic dysfunction after infusion of tumor necrosis factor-alpha in conscious dogs. J Clin Invest (1992) 1.29
Endotoxemia causes ileal mucosal acidosis in the absence of mucosal hypoxia in a normodynamic porcine model of septic shock. Crit Care Med (1995) 1.26
Nitric oxide dilates tight junctions and depletes ATP in cultured Caco-2BBe intestinal epithelial monolayers. Am J Physiol (1995) 1.25
EUK-8, a synthetic superoxide dismutase and catalase mimetic, ameliorates acute lung injury in endotoxemic swine. J Pharmacol Exp Ther (1995) 1.21
Nonoperative treatment of adult splenic trauma: development of a computed tomographic scoring system that detects appropriate candidates for expectant management. J Trauma (1988) 1.18
Effect of mesenteric ischemia and reperfusion or hemorrhagic shock on intestinal mucosal permeability and ATP content in rats. Shock (1999) 1.17
Interpreting dual-sugar absorption studies in critically ill patients: what are the implications of apparent increases in intestinal permeability to hydrophilic solutes? Intensive Care Med (1997) 1.09
Validation of tonometric measurement of gut intramural pH during endotoxemia and mesenteric occlusion in pigs. Am J Physiol (1990) 1.09
Norepinephrine alone versus norepinephrine plus low-dose dopamine: enhanced renal blood flow with combination pressor therapy. Crit Care Med (1985) 1.08
The participation of hydroperoxides and oxygen radicals in the control of prostaglandin synthesis. J Biol Chem (1983) 1.03
Cardiovascular performance with E. coli challenges in a canine model of human sepsis. Am J Physiol (1988) 1.02
Protective effects of a novel 32-amino acid C-terminal fragment of CAP18 in endotoxemic pigs. Surgery (1995) 1.02
Ex vivo application of carbon monoxide in University of Wisconsin solution to prevent intestinal cold ischemia/reperfusion injury. Am J Transplant (2006) 0.99
Inhibition of prostaglandin synthesis restores normal hemodynamics in canine hyperdynamic sepsis. Ann Surg (1984) 0.98
Acidosis induces hyperpermeability in Caco-2BBe cultured intestinal epithelial monolayers. Am J Physiol (1997) 0.97
Differential expression of inducible nitric oxide synthase messenger RNA along the longitudinal and crypt-villus axes of the intestine in endotoxemic rats. Crit Care Med (1998) 0.95
Bactericidal/permeability-increasing protein ameliorates acute lung injury in porcine endotoxemia. J Appl Physiol (1985) (1994) 0.95
Chemical hypoxia increases junctional permeability and activates electrogenic ion transport in human intestinal epithelial monolayers. Surgery (1994) 0.94
Nitric oxide mediates interferon-gamma-induced hyperpermeability in cultured human intestinal epithelial monolayers. Crit Care Med (1995) 0.94
Endotoxin-induced ileal mucosal hyperpermeability in pigs: role of tissue acidosis. Am J Physiol (1994) 0.94
Diminished pressor response to exogenous norepinephrine and angiotensin II in septic, unanesthetized rats: evidence for a prostaglandin-mediated effect. J Surg Res (1985) 0.93
Hyperpermeability and ATP depletion induced by chronic hypoxia or glycolytic inhibition in Caco-2BBe monolayers. Am J Physiol (1996) 0.92
Human neutrophil migration is enhanced by beta-endorphin. Life Sci (1984) 0.92
Nitric oxide donor-induced hyperpermeability of cultured intestinal epithelial monolayers: role of superoxide radical, hydroxyl radical, and peroxynitrite. Biochim Biophys Acta (1998) 0.92
Gastric tonometry in healthy volunteers: effect of ranitidine on calculated intramural pH. Crit Care Med (1991) 0.92
Intestinal epithelial hyperpermeability. Mechanisms and relevance to disease. Gastroenterol Clin North Am (1998) 0.91
Hyperpermeability of intestinal epithelial monolayers is induced by NO: effect of low extracellular pH. Am J Physiol (1997) 0.91
Assessment of hepatitis B virus immunization status among North American surgeons. Arch Surg (1994) 0.91
Determinants of intestinal barrier failure in critical illness. Br J Anaesth (1996) 0.91
How to keep up with the critical care literature and avoid being buried alive. Crit Care Med (1996) 0.89
Postoperative complications in patients with disabling psychiatric illnesses or intellectual handicaps. A case-controlled, retrospective analysis. Arch Surg (1990) 0.89
Intraluminal "balloonless" air tonometry: a new method for determination of gastrointestinal mucosal carbon dioxide tension. Crit Care Med (1994) 0.88
Lisofylline ameliorates intestinal and hepatic injury induced by hemorrhage and resuscitation in rats. Crit Care Med (2000) 0.88
Lisofylline ameliorates intestinal mucosal barrier dysfunction caused by ischemia and ischemia/reperfusion. Shock (1999) 0.88
Renal hemodynamics and prostaglandin E2 excretion in a nonhuman primate model of septic shock. Crit Care Med (1990) 0.86
Prospective randomized study of piperacillin/tazobactam therapy of surgically treated intra-abdominal infection. The Piperacillin/Tazobactam Intra-Abdominal Infection Study Group. Am Surg (1993) 0.86
Polymorphonuclear neutrophil chemiluminescence in whole blood from blunt trauma patients with multiple injuries. J Trauma (1999) 0.85
Does tissue acidosis in sepsis indicate tissue hypoperfusion? Intensive Care Med (1996) 0.85
Mesenteric dysfunction after cardiopulmonary bypass: role of complement C5a. Ann Thorac Surg (2000) 0.85
Hypoxic signal transduction in critical illness. Crit Care Med (2000) 0.84
Plasma levels of 6-keto PGF1 alpha but not TxB2 increase in rats with peritonitis due to cecal ligation. Circ Shock (1985) 0.84
Ileal mucosal oxygen consumption is decreased in endotoxemic rats but is restored toward normal by treatment with aminoguanidine. Crit Care Med (1999) 0.84
Prostaglandins and sepsis: still a fascinating topic despite almost 40 years of research. Am J Physiol Lung Cell Mol Physiol (2001) 0.83
The influence of gamma radiation on arachidonic acid release and prostacyclin synthesis. Prostaglandins (1983) 0.83
Delayed treatment with recombinant human tissue factor pathway inhibitor improves survival in rabbits with gram-negative peritonitis. J Infect Dis (1998) 0.83
Acquired interferon gamma responsiveness during Caco-2 cell differentiation: effects on iNOS gene expression. Gut (1999) 0.82
Load-insensitive assessment of myocardial performance after tumor necrosis factor-alpha in dogs. Surgery (1992) 0.82
Role of oxidant stress and iron delocalization in acidosis-induced intestinal epithelial hyperpermeability. Shock (1997) 0.82
Leaky gut hypothesis: a historical perspective. Crit Care Med (1990) 0.82
Antibody stimulation of tumour growth in T-cell depleted mice. Nature (1975) 0.81
Aminoglycoside pharmacokinetics: dosage requirements and nephrotoxicity in trauma patients. Crit Care Med (1989) 0.81
Microcirculatory weak units--an alternative explanation. Crit Care Med (2000) 0.81
P-glycoprotein-170 inhibition significantly reduces cortisol and ciclosporin efflux from human intestinal epithelial cells and T lymphocytes. Aliment Pharmacol Ther (2002) 0.81
A comparative evaluation of particulate and soluble glucan in an endotoxin model. Int J Immunopharmacol (1986) 0.81
Effect of human hemoglobin on systemic and regional hemodynamics in a porcine model of endotoxemic shock. Crit Care Med (1996) 0.80
Beneficial effects of LY203647, a novel leukotriene C4/D4 antagonist, on pulmonary function and mesenteric perfusion in a porcine model of endotoxic shock and ARDS. Circ Shock (1991) 0.80
LY255283, a novel leukotriene B4 receptor antagonist, limits activation of neutrophils and prevents acute lung injury induced by endotoxin in pigs. Surgery (1993) 0.79
Maintenance and down-regulation of primed neutrophil chemiluminescence activity in human whole blood. J Leukoc Biol (1997) 0.79
Mesenteric and skeletal muscle microvascular responsiveness in subacute sepsis. Shock (1998) 0.79
Selective digestive decontamination: a gut issue for the nineties. Crit Care Med (1992) 0.79
A novel leukotriene B4-receptor antagonist in endotoxin shock: a prospective, controlled trial in a porcine model. Crit Care Med (1993) 0.79
Pneumonia in patients with multiple trauma. Clin Chest Med (1995) 0.79
Current concepts in splenic trauma. J Intensive Care Med (1995) 0.79