Published in Exp Eye Res on June 01, 1997
Ophthalmic drug discovery: novel targets and mechanisms for retinal diseases and glaucoma. Nat Rev Drug Discov (2012) 1.52
Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue. Mol Vis (2006) 1.35
The cross-species A3 adenosine-receptor antagonist MRS 1292 inhibits adenosine-triggered human nonpigmented ciliary epithelial cell fluid release and reduces mouse intraocular pressure. Curr Eye Res (2005) 1.17
A(1)-, A(2A)- and A(3)-subtype adenosine receptors modulate intraocular pressure in the mouse. Br J Pharmacol (2001) 1.16
Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow. J Cell Physiol (2012) 1.06
Novel ocular antihypertensive compounds in clinical trials. Clin Ophthalmol (2011) 0.99
Advances in glaucoma treatment and management: outflow drugs. Invest Ophthalmol Vis Sci (2012) 0.96
Common actions of adenosine receptor agonists in modulating human trabecular meshwork cell transport. J Membr Biol (2003) 0.96
Distribution of adenosine receptors in human sclera fibroblasts. Mol Vis (2008) 0.93
Mechanisms of ATP release, the enabling step in purinergic dynamics. Cell Physiol Biochem (2011) 0.92
Effect of daily prolonged ketamine anesthesia on intraocular pressure in monkeys. Curr Eye Res (2008) 0.89
Effects of latrunculin B on outflow facility, intraocular pressure, corneal thickness, and miotic and accommodative responses to pilocarpine in monkeys. Trans Am Ophthalmol Soc (2004) 0.88
Cytoskeletal dependence of adenosine triphosphate release by human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 0.84
Pharmacotherapy of glaucoma. J Ocul Pharmacol Ther (2015) 0.84
Tamoxifen and ATP synergistically activate Cl- release by cultured bovine pigmented ciliary epithelial cells. J Physiol (2000) 0.81
A3 adenosine and CB1 receptors activate a PKC-sensitive Cl- current in human nonpigmented ciliary epithelial cells via a G beta gamma-coupled MAPK signaling pathway. Br J Pharmacol (2003) 0.81
Cell-specific differential modulation of human trabecular meshwork cells by selective adenosine receptor agonists. Exp Eye Res (2006) 0.79
Endogenous production of extracellular adenosine by trabecular meshwork cells: potential role in outflow regulation. Invest Ophthalmol Vis Sci (2012) 0.79
Electron probe X-ray microanalysis of intact pathway for human aqueous humor outflow. Am J Physiol Cell Physiol (2008) 0.79
Exciting directions in glaucoma. Can J Ophthalmol (2014) 0.78
Connexins form functional hemichannels in porcine ciliary epithelium. Exp Eye Res (2013) 0.77
A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of 2 and 4 Weeks of Twice-Daily Ocular Trabodenoson in Adults with Ocular Hypertension or Primary Open-Angle Glaucoma. J Ocul Pharmacol Ther (2016) 0.76
Drug discovery in ophthalmology: past success, present challenges, and future opportunities. BMC Ophthalmol (2016) 0.76
[Functional significance of adenosine receptors in the eye and their dysregulation in pseudoexfoliation syndrome]. Ophthalmologe (2005) 0.75
A Randomized Phase 1 Dose Escalation Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Trabodenoson in Healthy Adult Volunteers. J Ocul Pharmacol Ther (2016) 0.75
Ocular Purine Receptors as Drug Targets in the Eye. J Ocul Pharmacol Ther (2016) 0.75
Targeting Schlemm's Canal in the Medical Therapy of Glaucoma: Current and Future Considerations. Adv Ther (2017) 0.75
Use of phosphodiesterase inhibitors and prevalence of self-reported glaucoma in the United States. PLoS One (2017) 0.75
The Magnitude of Hypotony and Time Course of Intraocular Pressure Recovery Following Anterior Chamber Cannulation in Nonhuman Primates. Invest Ophthalmol Vis Sci (2017) 0.75
The mechanism of accommodation in primates. Ophthalmology (1999) 4.00
Scleral expansion surgery for presbyopia. Ophthalmology (2001) 2.55
Ocular effects of apraclonidine in Horner syndrome. Arch Ophthalmol (2000) 2.22
Dietary restriction of adult male rhesus monkeys: design, methodology, and preliminary findings from the first year of study. J Gerontol (1993) 2.17
Morphology of single ganglion cells in the glaucomatous primate retina. Invest Ophthalmol Vis Sci (1998) 1.81
Cytoskeletal involvement in the regulation of aqueous humor outflow. Invest Ophthalmol Vis Sci (2000) 1.72
Atrophy of relay neurons in magno- and parvocellular layers in the lateral geniculate nucleus in experimental glaucoma. Invest Ophthalmol Vis Sci (2001) 1.68
Accommodation and presbyopia in the human eye. Changes in the anterior segment and crystalline lens with focus. Invest Ophthalmol Vis Sci (1997) 1.67
Slit-lamp studies of the rhesus monkey eye: II. Changes in crystalline lens shape, thickness and position during accommodation and aging. Exp Eye Res (1987) 1.63
Loss of neurons in magnocellular and parvocellular layers of the lateral geniculate nucleus in glaucoma. Arch Ophthalmol (2000) 1.62
Experimental glaucoma and cell size, density, and number in the primate lateral geniculate nucleus. Invest Ophthalmol Vis Sci (2000) 1.59
Accommodation and presbyopia in the human eye--aging of the anterior segment. Vision Res (1989) 1.58
Reproducible stimulation of ciliary muscle contraction in the cynomolgus monkey via a permanent indwelling midbrain electrode. Brain Res (1989) 1.52
Age-dependent loss of accommodative amplitude in rhesus monkeys: an animal model for presbyopia. Invest Ophthalmol Vis Sci (1982) 1.46
Accommodation dynamics in aging rhesus monkeys. Am J Physiol (1998) 1.39
H-7 effects on the structure and fluid conductance of monkey trabecular meshwork. Arch Ophthalmol (2000) 1.35
Age changes in rhesus monkey ciliary muscle: light and electron microscopy. Exp Eye Res (1988) 1.33
Age-related loss of ciliary muscle mobility in the rhesus monkey. Role of the choroid. Arch Ophthalmol (1992) 1.33
Loss of acute pilocarpine effect on outflow facility following surgical disinsertion and retrodisplacement of the ciliary muscle from the scleral spur in the cynomolgus monkey. Invest Ophthalmol (1976) 1.30
Prostaglandin F2 alpha increases uveoscleral outflow in the cynomolgus monkey. Exp Eye Res (1989) 1.27
Total iridectomy in the primate in vivo: surgical technique and postoperative anatomy. Invest Ophthalmol (1975) 1.26
Slit-lamp studies of the rhesus monkey eye. I. Survey of the anterior segment. Exp Eye Res (1987) 1.21
The role of the iris in accommodation of rhesus monkeys. Invest Ophthalmol Vis Sci (1990) 1.20
Non-invasive observation of repeated adenoviral GFP gene delivery to the anterior segment of the monkey eye in vivo. J Gene Med (2001) 1.19
Pilocarpine antagonizes prostaglandin F2 alpha-induced ocular hypotension in monkeys. Evidence for enhancement of Uveoscleral outflow by prostaglandin F2 alpha. Arch Ophthalmol (1987) 1.19
Epithelial wound closure in the rabbit cornea. A biphasic process. Invest Ophthalmol Vis Sci (1986) 1.18
Presbyopia: an animal model and experimental approaches for the study of the mechanism of accommodation and ocular ageing. Eye (Lond) (1987) 1.18
In vivo videography of the rhesus monkey accommodative apparatus. Age-related loss of ciliary muscle response to central stimulation. Arch Ophthalmol (1990) 1.17
"Minified" Goldmann applanating prism for tonometry in monkeys and humans. Arch Ophthalmol (1980) 1.17
Increased elastin expression in astrocytes of the lamina cribrosa in response to elevated intraocular pressure. Invest Ophthalmol Vis Sci (2001) 1.13
Topical prostaglandin F2alpha treatment reduces collagen types I, III, and IV in the monkey uveoscleral outflow pathway. Arch Ophthalmol (1999) 1.13
Age-related loss of morphologic responses to pilocarpine in rhesus monkey ciliary muscle. Arch Ophthalmol (1988) 1.12
Effect of latrunculin-B on outflow facility in monkeys. Exp Eye Res (2000) 1.12
Follow-up of angle-closure glaucoma suspects. Am J Ophthalmol (1993) 1.09
Transport processes across the rabbit corneal epithelium: a review. Curr Eye Res (1985) 1.08
Intravitreal injection of plasminogen kringle 5, an endogenous angiogenic inhibitor, arrests retinal neovascularization in rats. Diabetologia (2001) 1.07
Latrunculin-A increases outflow facility in the monkey. Invest Ophthalmol Vis Sci (1999) 1.07
H-7 disrupts the actin cytoskeleton and increases outflow facility. Arch Ophthalmol (1998) 1.06
The development of presbyopia in primates. Trans Ophthalmol Soc U K (1982) 1.04
Inhibition of outflow facility and accommodative and miotic responses to pilocarpine in rhesus monkeys by muscarinic receptor subtype antagonists. J Pharmacol Exp Ther (1992) 1.04
Effects of topical PGF2 alpha on aqueous humor dynamics in cynomolgus monkeys. Curr Eye Res (1987) 1.03
Increased matrix metalloproteinases 1, 2, and 3 in the monkey uveoscleral outflow pathway after topical prostaglandin F(2 alpha)-isopropyl ester treatment. Arch Ophthalmol (2001) 1.01
The effect of prostaglandin F2 alpha on trabecular outflow facility in cynomolgus monkeys. Exp Eye Res (1990) 1.00
Aging of the human lens: changes in lens shape at zero-diopter accommodation. J Opt Soc Am A Opt Image Sci Vis (2001) 1.00
Ultrasound biomicroscopy of the aging rhesus monkey ciliary region. Optom Vis Sci (2001) 0.99
Latrunculins' effects on intraocular pressure, aqueous humor flow, and corneal endothelium. Invest Ophthalmol Vis Sci (2000) 0.98
Parasympathetic denervation of the ciliary muscle following panretinal photocoagulation. Curr Eye Res (1991) 0.97
Adjunctive mitomycin C in Molteno implant surgery. Ophthalmology (1995) 0.97
Anticholinesterase-induced cholinergic subsensitivity in primate accommodative mechanism. Am J Ophthalmol (1978) 0.97
Aging of the human crystalline lens and anterior segment. Vision Res (1994) 0.97
Accommodation and presbyopia. Int Ophthalmol Clin (2001) 0.96
Age does not affect contractile responses of the isolated rhesus monkey ciliary muscle to muscarinic agonists. Curr Eye Res (1993) 0.96
Prostaglandin F2 alpha effects on isolated rhesus monkey ciliary muscle. Invest Ophthalmol Vis Sci (1995) 0.95
Prognosis of primary rhegmatogenous retinal detachments. 2. Accounting for and predicting final visual acuity in surgically reattached cases. Acta Ophthalmol (Copenh) (1976) 0.95
Cytochalasin B and D dose-outflow facility response relationships in the cynomolgus monkey. Invest Ophthalmol Vis Sci (1982) 0.93
Intraocular pressure measurement in cynomolgus monkeys. Tono-Pen versus manometry. Invest Ophthalmol Vis Sci (1996) 0.92
Intraocular pressure measurement after penetrating keratoplasty: minified Goldmann applanation tonometer, pneumatonometer, and Tono-Pen versus manometry. Br J Ophthalmol (1994) 0.92
Long-term activation of c-Fos and c-Jun in optic nerve head astrocytes in experimental ocular hypertension in monkeys and after exposure to elevated pressure in vitro. Brain Res (2005) 0.92
Effect of 8-Br cGMP on aqueous humor dynamics in monkeys. Invest Ophthalmol Vis Sci (1994) 0.92
Aging of the human crystalline lens and presbyopia. Int Ophthalmol Clin (2001) 0.91
Effect of latrunculin-A on morphology and actin-associated adhesions of cultured human trabecular meshwork cells. Mol Vis (2000) 0.91
Ciliary muscle muscarinic binding sites, choline acetyltransferase, and acetylcholinesterase in aging rhesus monkeys. Invest Ophthalmol Vis Sci (1990) 0.91
Gene therapy using p21WAF-1/Cip-1 to modulate wound healing after glaucoma trabeculectomy surgery in a primate model of ocular hypertension. Gene Ther (2004) 0.90
Recent observations concerning the effects of cholinergic drugs on outflow facility in monkeys. Exp Eye Res (1977) 0.89
Combined effects of H-7 and cytochalasin B on outflow facility in monkeys. Exp Eye Res (1999) 0.89
A short-term follow-up study on ex-cigarette smokers. With special emphasis on persistent cough and weight gain. Am Rev Respir Dis (1967) 0.89
Association of retinal capillary perfusion with visual status during chronic glaucoma therapy. Ophthalmology (1997) 0.89
Apraclonidine and brimonidine effects on anterior ocular and cardiovascular physiology in normal and sympathectomized monkeys. Exp Eye Res (1994) 0.89
Aging effects on accommodation and outflow facility responses to pilocarpine in humans. Arch Ophthalmol (1996) 0.88
Intraocular pressure and outflow facility are unchanged following acute and chronic intracameral chondroitinase ABC and hyaluronidase in monkeys. Exp Eye Res (1997) 0.88
Accommodation and ciliary muscle muscarinic receptors after echothiophate. Invest Ophthalmol Vis Sci (1991) 0.88
Comparative effects of three ocular perfusates on outflow facility in the cynomolgus monkey. Curr Eye Res (1981) 0.88
Ciliary neuromuscular morphology in cynomolgus monkeys after ciliary ganglionectomy. Graefes Arch Clin Exp Ophthalmol (1990) 0.88
Comparative aqueous outflow facility measurements by pneumatonography and Schiotz tonography. Invest Ophthalmol Vis Sci (1986) 0.88
Effects of various anesthetic and autonomic drugs on refraction in monkeys. Curr Eye Res (1990) 0.88
Acute and chronic structural effects of pilocarpine on monkey outflow tissues. Trans Am Ophthalmol Soc (1998) 0.87
Comparative anesthetic effects on aqueous humor dynamics in the cynomolgus monkey. Arch Ophthalmol (1984) 0.87
Herpes simplex virus mediated gene transfer to primate ocular tissues. Exp Eye Res (1999) 0.87
The effect of muscarinic agonists and selective receptor subtype antagonists on the contractile response of the isolated rhesus monkey ciliary muscle. Exp Eye Res (1994) 0.87
The occurrence of senile cataracts, ocular hypertension and glaucoma in rhesus monkeys. Exp Eye Res (1982) 0.87
Alteration of corneal epithelial ion transport by sympathectomy. Invest Ophthalmol Vis Sci (1985) 0.87
Effects of intracamerally infused prostaglandins on outflow facility in cynomolgus monkey eyes with intact or retrodisplaced ciliary muscle. Exp Eye Res (1986) 0.87
Acute effects of H-7 on ciliary epithelium and corneal endothelium in monkey eyes. Curr Eye Res (2001) 0.87
Low dose latrunculin-A inhibits dexamethasone-induced changes in the actin cytoskeleton and alters extracellular matrix protein expression in cultured human trabecular meshwork cells. Exp Eye Res (2003) 0.86
H-7 increases trabecular facility and facility after ciliary muscle disinsertion in monkeys. Invest Ophthalmol Vis Sci (1999) 0.86
Cytochalasin B-induced structural changes in the anterior ocular segment of the cynomolgus monkey. Invest Ophthalmol Vis Sci (1978) 0.86
Echothiophate-induced structural alterations in the anterior chamber angle of the cynomolgus monkey. Invest Ophthalmol Vis Sci (1979) 0.86