D W Frank

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 ExoU expression by Pseudomonas aeruginosa correlates with acute cytotoxicity and epithelial injury. Mol Microbiol 1997 4.94
2 Type III protein secretion is associated with death in lower respiratory and systemic Pseudomonas aeruginosa infections. J Infect Dis 2001 4.06
3 ExoY, an adenylate cyclase secreted by the Pseudomonas aeruginosa type III system. Proc Natl Acad Sci U S A 1998 4.04
4 Exoenzyme S of Pseudomonas aeruginosa is secreted by a type III pathway. Mol Microbiol 1996 3.55
5 Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury. Nat Med 1999 3.51
6 Pseudomonas aeruginosa-mediated cytotoxicity and invasion correlate with distinct genotypes at the loci encoding exoenzyme S. Infect Immun 1997 3.49
7 O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats. J Biol Chem 1997 3.16
8 Pathogenesis of septic shock in Pseudomonas aeruginosa pneumonia. J Clin Invest 1999 2.67
9 Identification of type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulon. J Bacteriol 1997 2.58
10 Genetic relationship between the 53- and 49-kilodalton forms of exoenzyme S from Pseudomonas aeruginosa. J Bacteriol 1996 2.33
11 Regulation of ExoS production and secretion by Pseudomonas aeruginosa in response to tissue culture conditions. Infect Immun 1999 2.32
12 Analyses of the DNA-binding and transcriptional activation properties of ExsA, the transcriptional activator of the Pseudomonas aeruginosa exoenzyme S regulon. J Bacteriol 1995 2.32
13 Transcriptional analysis of the Pseudomonas aeruginosa exoenzyme S structural gene. J Bacteriol 1995 2.27
14 Biological effects of Pseudomonas aeruginosa type III-secreted proteins on CHO cells. Infect Immun 1999 2.15
15 Cloning the structural gene for the 49-kDa form of exoenzyme S (exoS) from Pseudomonas aeruginosa strain 388. J Biol Chem 1994 1.82
16 Transcriptional organization of the trans-regulatory locus which controls exoenzyme S synthesis in Pseudomonas aeruginosa. J Bacteriol 1994 1.82
17 The amino-terminal domain of Pseudomonas aeruginosa ExoS disrupts actin filaments via small-molecular-weight GTP-binding proteins. Mol Microbiol 1999 1.81
18 The pleckstrin homology domains of dynamin isoforms require oligomerization for high affinity phosphoinositide binding. J Biol Chem 1998 1.75
19 Pseudomonas aeruginosa exoenzyme S ADP-ribosylates Ras at multiple sites. J Biol Chem 1998 1.73
20 In vitro cellular toxicity predicts Pseudomonas aeruginosa virulence in lung infections. Infect Immun 1998 1.63
21 In vivo Himar1-based transposon mutagenesis of Francisella tularensis. Appl Environ Microbiol 2006 1.63
22 Expression of recombinant exoenzyme S of Pseudomonas aeruginosa. Infect Immun 1995 1.60
23 Purification and characterization of exoenzyme S from Pseudomonas aeruginosa 388. Infect Immun 1993 1.60
24 Role of exoenzyme S in chronic Pseudomonas aeruginosa lung infections. Eur J Clin Microbiol 1985 1.59
25 Effects of differential expression of the 49-kilodalton exoenzyme S by Pseudomonas aeruginosa on cultured eukaryotic cells. Infect Immun 1997 1.57
26 Multiple promoters control the regulation of the Pseudomonas aeruginosa regA gene. Mol Microbiol 1990 1.51
27 Type III secretion/intoxication system important in virulence of Pseudomonas aeruginosa infections in burns. Burns 2001 1.51
28 Modification of Ras in eukaryotic cells by Pseudomonas aeruginosa exoenzyme S. Infect Immun 1998 1.50
29 Pseudomonas aeruginosa invasion and cytotoxicity are independent events, both of which involve protein tyrosine kinase activity. Infect Immun 1998 1.49
30 Identification of regB, a gene required for optimal exotoxin A yields in Pseudomonas aeruginosa. Mol Microbiol 1990 1.48
31 A cytoplasmic sequence in human tyrosinase defines a second class of di-leucine-based sorting signals for late endosomal and lysosomal delivery. J Biol Chem 1999 1.46
32 Macrophages and epithelial cells respond differently to the Pseudomonas aeruginosa type III secretion system. Infect Immun 1999 1.46
33 ExoT of cytotoxic Pseudomonas aeruginosa prevents uptake by corneal epithelial cells. Infect Immun 2000 1.43
34 Interaction of monoclonal antibodies with pertussis toxin and its subunits. Infect Immun 1984 1.40
35 Molecular studies of a positive regulator of toxin A synthesis in Pseudomonas aeruginosa. Antibiot Chemother (1971) 1987 1.38
36 Identification and characterization of SpcU, a chaperone required for efficient secretion of the ExoU cytotoxin. J Bacteriol 1998 1.35
37 Multiple domains are required for the toxic activity of Pseudomonas aeruginosa ExoU. J Bacteriol 2001 1.35
38 Biochemical relationships between the 53-kilodalton (Exo53) and 49-kilodalton (ExoS) forms of exoenzyme S of Pseudomonas aeruginosa. J Bacteriol 1997 1.30
39 Dominant-negative inhibition of receptor-mediated endocytosis by a dynamin-1 mutant with a defective pleckstrin homology domain. Curr Biol 1999 1.23
40 A common temperature-sensitive allelic form of human tyrosinase is retained in the endoplasmic reticulum at the nonpermissive temperature. J Biol Chem 2000 1.21
41 Effect of Pseudomonas aeruginosa elastase, alkaline protease, and exotoxin A on corneal proteinases and proteins. Invest Ophthalmol Vis Sci 1993 1.20
42 Structure, function, and regulation of Pseudomonas aeruginosa exotoxin A. Annu Rev Microbiol 1990 1.18
43 Cytotoxic strains of Pseudomonas aeruginosa can damage the intact corneal surface in vitro. CLAO J 1998 1.17
44 PcrV immunization enhances survival of burned Pseudomonas aeruginosa-infected mice. Infect Immun 2001 1.16
45 Isolation and characterization of monoclonal antibodies to Bordetella pertussis. J Biol Stand 1984 1.15
46 Characterization of a gene that regulates toxin A synthesis in Pseudomonas aeruginosa. Nucleic Acids Res 1988 1.14
47 Effect of regB on expression from the P1 and P2 promoters of the Pseudomonas aeruginosa regAB operon. J Bacteriol 1991 1.13
48 Interruption of multiple cellular processes in HT-29 epithelial cells by Pseudomonas aeruginosa exoenzyme S. Infect Immun 1999 1.11
49 Sera from adult patients with cystic fibrosis contain antibodies to Pseudomonas aeruginosa type III apparatus. Infect Immun 2001 1.06
50 Intracellular localization and processing of Pseudomonas aeruginosa ExoS in eukaryotic cells. Mol Microbiol 2000 1.02
51 Cultivation of two species of Neorickettsia in canine monocytes. J Infect Dis 1974 0.99
52 Functional analysis of exsC and exsB in regulation of exoenzyme S production by Pseudomonas aeruginosa. J Bacteriol 1997 0.95
53 Induction of dolichyl-saccharide intermediate biosynthesis corresponds to increased long chain cis-isoprenyltransferase activity during the mitogenic response in mouse B cells. J Biol Chem 1994 0.95
54 Genetic analysis of exoenzyme S expression by Pseudomonas aeruginosa. FEMS Microbiol Lett 1996 0.94
55 Lymphoreticular lesions of canine neorickettsiosis. J Infect Dis 1974 0.91
56 Cyclodextrin nephrosis in the rat. Am J Pathol 1976 0.87
57 Cell surface antigens of Bordetella pertussis. Dev Biol Stand 1985 0.81
58 Surface antigens of Bordetella pertussis. Adv Exp Med Biol 1985 0.81
59 Mammary tumors and serum hormones in the bitch treated with medroxyprogesterone acetate or progesterone for four years. Fertil Steril 1979 0.80
60 A 6-month dietary toxicity study of acidic sodium aluminium phosphate in beagle dogs. Food Chem Toxicol 1984 0.77
61 Vacuolation in renal tubular epithelium of Cd-1 mice: an incidental finding. Toxicol Pathol 1999 0.76
62 Isolation and characterization of an attenuated strain of Pseudomonas aeruginosa AC869, a 3,5-dichlorobenzoate degrader. Appl Environ Microbiol 1997 0.75
63 Developmental changes in enzymes involved in dolichyl phosphate metabolism in cultured embryonic rat brain cells. J Neurochem 1991 0.75
64 Renal changes associated with naproxen sodium administration in cynomolgus monkeys. Toxicol Pathol 1999 0.75
65 A comparison of two methods for evaluating drug-induced chromosome alterations. Mutat Res 1978 0.75
66 Antifertility activity of DMA in hamsters: protection with a luteotropic complex. Proc Soc Exp Biol Med 1981 0.75
67 Toxicity and exposure of an adenovirus containing human interferon alpha-2b following intracystic administration in cynomolgus monkeys. Gene Ther 2011 0.75
68 The effect of the germfree state on wound healing. J Surg Res 1971 0.75