L S Tobacman

Author PubWeight™ 41.39‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The kinetics of actin nucleation and polymerization. J Biol Chem 1983 2.70
2 Tropomyosin and actin isoforms modulate the localization of tropomyosin strands on actin filaments. J Mol Biol 2000 2.43
3 The regulation of actin polymerization and the inhibition of monomeric actin ATPase activity by Acanthamoeba profilin. J Biol Chem 1982 1.60
4 Altered cardiac troponin T in vitro function in the presence of a mutation implicated in familial hypertrophic cardiomyopathy. J Clin Invest 1996 1.57
5 Calcium regulation of thin filament movement in an in vitro motility assay. Biophys J 1996 1.49
6 Effect of Acanthamoeba profilin on the pre-steady state kinetics of actin polymerization and on the concentration of F-actin at steady state. J Biol Chem 1983 1.43
7 Regulation of force and unloaded sliding speed in single thin filaments: effects of regulatory proteins and calcium. J Physiol 2000 1.31
8 Isolation and functional comparison of bovine cardiac troponin T isoforms. J Biol Chem 1987 1.29
9 Troponin organization on relaxed and activated thin filaments revealed by electron microscopy and three-dimensional reconstruction. J Mol Biol 2001 1.23
10 Analysis of troponin-tropomyosin binding to actin. Troponin does not promote interactions between tropomyosin molecules. J Biol Chem 1992 1.22
11 Roles for the troponin tail domain in thin filament assembly and regulation. A deletional study of cardiac troponin T. J Biol Chem 1999 1.22
12 Mechanism of regulation of cardiac actin-myosin subfragment 1 by troponin-tropomyosin. Biochemistry 1986 1.21
13 Hypertrophic cardiomyopathy caused by a novel alpha-tropomyosin mutation (V95A) is associated with mild cardiac phenotype, abnormal calcium binding to troponin, abnormal myosin cycling, and poor prognosis. Circulation 2001 1.09
14 Modulation of contractile activation in skeletal muscle by a calcium-insensitive troponin C mutant. J Biol Chem 2001 1.09
15 Effects of tropomyosin internal deletions on thin filament function. J Biol Chem 1999 1.08
16 Opposite effects of myosin subfragment 1 on binding of cardiac troponin and tropomyosin to the thin filament. J Biol Chem 1996 1.07
17 Cooperative interactions between adjacent troponin-tropomyosin complexes may be transmitted through the actin filament. J Biol Chem 1993 1.06
18 The active state of the thin filament is destabilized by an internal deletion in tropomyosin. J Biol Chem 1997 1.04
19 Contractile effects of the exchange of cardiac troponin for fast skeletal troponin in rabbit psoas single myofibrils. J Physiol 2003 1.02
20 Regulatory proteins alter nucleotide binding to acto-myosin of sliding filaments in motility assays. Biophys J 2003 1.01
21 Modulation of myosin function by isoform-specific properties of Saccharomyces cerevisiae and muscle tropomyosins. J Biol Chem 2001 0.99
22 Cooperative effect of calcium binding to adjacent troponin molecules on the thin filament-myosin subfragment 1 MgATPase rate. J Biol Chem 1997 0.95
23 Enzymatic comparisons between light chain isozymes of human cardiac myosin subfragment-1. J Biol Chem 1984 0.95
24 Molecular polarity in tropomyosin-troponin T co-crystals. Biophys J 1997 0.94
25 Equilibrium linkage analysis of cardiac thin filament assembly. Implications for the regulation of muscle contraction. J Biol Chem 1994 0.94
26 Mutations in actin subdomain 3 that impair thin filament regulation by troponin and tropomyosin. J Biol Chem 1999 0.93
27 NH2-terminal truncation of skeletal muscle troponin T does not alter the Ca2+ sensitivity of thin filament assembly. J Biol Chem 1995 0.89
28 Effects of cardiac thin filament Ca2+: statistical mechanical analysis of a troponin C site II mutant. Biophys J 1996 0.88
29 Effects of the amino-terminal regions of tropomyosin and troponin T on thin filament assembly. J Biol Chem 1992 0.88
30 Effects of a cardiomyopathy-causing troponin t mutation on thin filament function and structure. J Biol Chem 2001 0.87
31 Bovine cardiac troponin T: amino acid sequences of the two isoforms. Biochemistry 1987 0.86
32 Three-dimensional reconstruction of thin filaments containing mutant tropomyosin. Biophys J 2000 0.86
33 An actin subdomain 2 mutation that impairs thin filament regulation by troponin and tropomyosin. J Biol Chem 2000 0.85
34 Cooperative interactions between troponin molecules bound to the cardiac thin filament. J Biol Chem 1991 0.84
35 Activation of actin-cardiac myosin subfragment 1 MgATPase rate by Ca2+ shows cooperativity intrinsic to the thin filament. Biochemistry 1987 0.83
36 Mechanical and kinetic effects of shortened tropomyosin reconstituted into myofibrils. Pflugers Arch 2009 0.81
37 Highlights of the Molecular Interactions of Actin meeting, Hawaii, 1-5 April 1997. J Muscle Res Cell Motil 1998 0.75