Prostaglandin E2 and tumor necrosis factor alpha cooperate to activate human dendritic cells: synergistic activation of interleukin 12 production.

PubWeight™: 2.14‹?› | Rank: Top 2%

🔗 View Article (PMC 2199106)

Published in J Exp Med on November 03, 1997

Authors

C Rieser1, G Böck, H Klocker, G Bartsch, M Thurnher

Author Affiliations

1: Department of Urology, University of Innsbruck, A-6020 Innsbruck, Austria.

Articles citing this

Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. J Exp Med (2001) 7.46

Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes. J Exp Med (1998) 5.59

Regulation of immune responses by prostaglandin E2. J Immunol (2012) 3.93

Combining radiotherapy and immunotherapy: a revived partnership. Int J Radiat Oncol Biol Phys (2005) 2.29

Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells. Blood (2011) 2.05

A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation. Blood (2005) 2.01

Type I IFN controls chikungunya virus via its action on nonhematopoietic cells. J Exp Med (2010) 1.86

Comparative analysis of genetically modified dendritic cells and tumor cells as therapeutic cancer vaccines. J Exp Med (2000) 1.71

Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes. J Exp Med (2005) 1.71

TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice. J Clin Invest (2007) 1.63

In vitro differentiation of dendritic cells in the presence of prostaglandin E2 alters the IL-12/IL-23 balance and promotes differentiation of Th17 cells. J Immunol (2008) 1.63

A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels. Proc Natl Acad Sci U S A (1998) 1.62

Immune response in patients with newly diagnosed glioblastoma multiforme treated with intranodal autologous tumor lysate-dendritic cell vaccination after radiation chemotherapy. J Immunother (2011) 1.41

Paracoccidioides brasiliensis interferes on dendritic cells maturation by inhibiting PGE2 production. PLoS One (2015) 1.41

In vitro priming and expansion of cytomegalovirus-specific Th1 and Tc1 T cells from naive cord blood lymphocytes. Blood (2006) 1.37

Cytosolic phospholipase A2 alpha-deficient mice are resistant to experimental autoimmune encephalomyelitis. J Exp Med (2005) 1.30

Butyrate affects differentiation, maturation and function of human monocyte-derived dendritic cells and macrophages. Clin Exp Immunol (2002) 1.17

Emergency granulopoiesis promotes neutrophil-dendritic cell encounters that prevent mouse lung allograft acceptance. Blood (2011) 1.12

Histamine and prostaglandin E up-regulate the production of Th2-attracting chemokines (CCL17 and CCL22) and down-regulate IFN-gamma-induced CXCL10 production by immature human dendritic cells. Immunology (2006) 1.10

Prostaglandin E2 is a potent regulator of interleukin-12- and interleukin-18-induced natural killer cell interferon-gamma synthesis. Immunology (2004) 1.10

Functional and transcriptional profiling of MUTZ-3, a myeloid cell line acting as a model for dendritic cells. Immunology (2006) 1.07

Cyclooxygenase-2 deficiency enhances Th2 immune responses and impairs neutrophil recruitment in hepatic ischemia/reperfusion injury. J Immunol (2008) 1.07

Interaction of rotavirus with human myeloid dendritic cells. J Virol (2005) 1.03

PGE(2) suppression of innate immunity during mucosal bacterial infection. Front Cell Infect Microbiol (2013) 0.96

Calcium signaling through phospholipase C activates dendritic cells to mature and is necessary for the activation and maturation of dendritic cells induced by diverse agonists. Clin Diagn Lab Immunol (2004) 0.95

Manifestations of immune tolerance in the human female reproductive tract. Front Immunol (2013) 0.94

Genetic deletion of mPGES-1 abolishes PGE2 production in murine dendritic cells and alters the cytokine profile, but does not affect maturation or migration. Prostaglandins Leukot Essent Fatty Acids (2010) 0.92

Tumour necrosis factor-alpha (TNF-alpha) transgene-expressing dendritic cells (DCs) undergo augmented cellular maturation and induce more robust T-cell activation and anti-tumour immunity than DCs generated in recombinant TNF-alpha. Immunology (2003) 0.91

Prostaglandin E2 is a negative regulator on human plasmacytoid dendritic cells. Immunology (2006) 0.91

Reciprocal crosstalk between dendritic cells and natural killer cells under the effects of PGE2 in immunity and immunopathology. Cell Mol Immunol (2013) 0.90

The SOCS3-independent expression of IDO2 supports the homeostatic generation of T regulatory cells by human dendritic cells. J Immunol (2014) 0.89

Cholera toxin indirectly activates human monocyte-derived dendritic cells in vitro through the production of soluble factors, including prostaglandin E(2) and nitric oxide. Clin Vaccine Immunol (2006) 0.89

Placentally derived prostaglandin E2 acts via the EP4 receptor to inhibit IL-2-dependent proliferation of CTLL-2 T cells. Clin Exp Immunol (2002) 0.89

Calcitonin gene-related peptide inhibits lipopolysaccharide-induced interleukin-12 release from mouse peritoneal macrophages, mediated by the cAMP pathway. Immunology (2000) 0.88

Harnessing naturally occurring tumor immunity: a clinical vaccine trial in prostate cancer. PLoS One (2010) 0.88

Dendritic Cell Therapy in an Allogeneic-Hematopoietic Cell Transplantation Setting: An Effective Strategy toward Better Disease Control? Front Immunol (2014) 0.86

Fibroblasts inhibit the production of interleukin-12p70 by murine dendritic cells. Immunology (2003) 0.85

Interferon-gamma Added During Bacillus Calmette-Guerin Induced Dendritic Cell Maturation Stimulates Potent Th1 Immune Responses. J Transl Med (2003) 0.85

Cyclooxygenase-independent inhibition of dendritic cell maturation by aspirin. Immunology (2000) 0.84

Regulation of STAT pathways and IRF1 during human dendritic cell maturation by TNF-alpha and PGE2. J Leukoc Biol (2008) 0.84

Mycophenolate mofetil inhibits differentiation, maturation and allostimulatory function of human monocyte-derived dendritic cells. Clin Exp Immunol (2003) 0.84

Role of natural interferon-producing cells and T lymphocytes in porcine monocyte-derived dendritic cell maturation. Immunology (2006) 0.83

Vascular endothelial growth factor-A enhances indoleamine 2,3-dioxygenase expression by dendritic cells and subsequently impacts lymphocyte proliferation. Mem Inst Oswaldo Cruz (2013) 0.83

Human Primary Immune Cells Exhibit Distinct Mechanical Properties that Are Modified by Inflammation. Biophys J (2015) 0.83

Characterization of direct radiation-induced immune function and molecular signaling changes in an antigen presenting cell line. Clin Immunol (2013) 0.82

Interleukin-4 inhibits cyclo-oxygenase-2 expression and prostaglandin E production by human mature dendritic cells. Immunology (2006) 0.81

Eicosanoid modulation by the short-chain fatty acid n-butyrate in human monocytes. Immunology (2013) 0.81

Human beta-defensin 3 induces maturation of human langerhans cell-like dendritic cells: an antimicrobial peptide that functions as an endogenous adjuvant. J Invest Dermatol (2012) 0.80

Human Bone Marrow-Derived Mesenchymal Stromal Cells Differentially Inhibit Cytokine Production by Peripheral Blood Monocytes Subpopulations and Myeloid Dendritic Cells. Stem Cells Int (2015) 0.80

Antithetical effects of hemicellulase-treated Agaricus blazei on the maturation of murine bone-marrow-derived dendritic cells. Immunology (2005) 0.79

Monitoring of CD4+ and CD8+ T-cell responses after dendritic cell-based immunotherapy using CFSE dye dilution analysis. J Clin Immunol (2004) 0.79

Fibroblast and T cells conditioned media induce maturation dendritic cell and promote T helper immune response. Vet Res Forum (2012) 0.79

PGE2-induced IDO1 inhibits the capacity of fully mature DCs to elicit an in vitro antileukemic immune response. J Immunol Res (2015) 0.79

PGI₂ signaling inhibits antigen uptake and increases migration of immature dendritic cells. J Leukoc Biol (2013) 0.78

Phenotypic and functional characteristics of dendritic cells derived from human peripheral blood monocytes. J Zhejiang Univ Sci B (2005) 0.78

Generation of a cord blood-derived Wilms Tumor 1 dendritic cell vaccine for AML patients treated with allogeneic cord blood transplantation. Oncoimmunology (2015) 0.78

Immunomodulation by mesenchymal stem cells: Interplay between mesenchymal stem cells and regulatory lymphocytes. World J Stem Cells (2016) 0.78

Modulation of dendritic cell function by PGE2 and DHA: a framework for understanding the role of dendritic cells in neuroinflammation. Clin Lipidol (2011) 0.77

Suppression of established hepatocarcinoma in adjuvant only immunotherapy: alum triggers anti-tumor CD8(+) T cell response. Sci Rep (2015) 0.77

Augmentation of natural killer cell activity in mice by oral administration of transforming growth factor-beta. Immunology (1998) 0.76

Epigenetic regulations of inflammatory cyclooxygenase-derived prostanoids: molecular basis and pathophysiological consequences. Mediators Inflamm (2015) 0.75

Implications of chemokine receptors and inflammatory lipids in cancer. Immunotargets Ther (2013) 0.75

Articles cited by this

Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev (1991) 42.38

The dendritic cell system and its role in immunogenicity. Annu Rev Immunol (1991) 23.09

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med (1994) 21.52

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu Rev Immunol (1995) 10.65

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J Exp Med (1995) 9.79

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J Exp Med (1996) 9.31

Proliferating dendritic cell progenitors in human blood. J Exp Med (1994) 7.67

Prostaglandins as potentiators of increased vascular permeability in inflammation. Nature (1973) 6.34

Activation of human dendritic cells through CD40 cross-linking. J Exp Med (1994) 6.16

The instructive role of innate immunity in the acquired immune response. Science (1996) 5.50

High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10. J Exp Med (1996) 5.29

Origin, maturation and antigen presenting function of dendritic cells. Curr Opin Immunol (1997) 5.21

Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability. J Immunol Methods (1996) 4.87

CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells. Proc Natl Acad Sci U S A (1996) 4.64

Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood. J Immunol Methods (1996) 3.80

Quantitative analysis of cytokine gene expression in rheumatoid arthritis. J Immunol (1990) 3.57

Prostaglandins, aspirin-like drugs and the oedema of inflammation. Nature (1973) 3.20

Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production. J Exp Med (1995) 2.98

Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2. J Exp Med (1994) 2.69

Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes. J Immunol (1993) 2.63

New insights into the mobilization and phagocytic activity of dendritic cells. J Exp Med (1996) 2.38

A new view of prostaglandin E regulation of the immune response. Immunol Today (1991) 2.36

Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo. J Exp Med (1996) 2.28

Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: evidence for a soluble CD14-dependent pathway. J Immunol (1997) 2.23

Different cytokine profiles in the synovial fluid of patients with osteoarthritis, rheumatoid arthritis and seronegative spondylarthropathies. Clin Exp Rheumatol (1996) 1.44

The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice. J Exp Med (1996) 1.37

Prostaglandin E2 at priming of naive CD4+ T cells inhibits acquisition of ability to produce IFN-gamma and IL-2, but not IL-4 and IL-5. J Immunol (1995) 1.36

Bacillus Calmette-Guérin mycobacteria stimulate human blood dendritic cells. Int J Cancer (1997) 1.19

Ceramide inhibits antigen uptake and presentation by dendritic cells. J Exp Med (1996) 1.16

Antigen-driven but not lipopolysaccharide-driven IL-12 production in macrophages requires triggering of CD40. J Immunol (1997) 1.12

Accessory cell-derived IL-12 and prostaglandin E2 determine the IFN-gamma level of activated human CD4+ T cells. J Immunol (1996) 1.11

Enhanced prostanoid release from monocytes of patients with rheumatoid arthritis and active systemic lupus erythematosus. Ann Rheum Dis (1985) 1.05

Up-regulation of tubular epithelial interleukin-12 in autoimmune MRL-Fas(lpr) mice with renal injury. Kidney Int (1997) 1.03

A cyclic adenosine 3',5'-monophosphate signal is required for the induction of IL-1 beta by TNF-alpha in human monocytes. J Immunol (1995) 0.92

In vitro generation of CD83+ human blood dendritic cells for active tumor immunotherapy. Exp Hematol (1997) 0.90

Articles by these authors

Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor. Cancer Res (1994) 3.43

The efficacy of dihydrotestosterone transdermal gel before primary hypospadias surgery: a prospective, controlled, randomized study. J Urol (2007) 2.85

Analysis of 462 transplantations from unrelated donors facilitated by the National Marrow Donor Program. N Engl J Med (1993) 2.85

Tumor necrosis factor alpha maintains the viability of murine epidermal Langerhans cells in culture, but in contrast to granulocyte/macrophage colony-stimulating factor, without inducing their functional maturation. J Exp Med (1990) 2.82

Switch from antagonist to agonist of the androgen receptor bicalutamide is associated with prostate tumour progression in a new model system. Br J Cancer (1999) 2.34

Detection of prostate cancer with a microbubble ultrasound contrast agent. Lancet (2001) 2.23

Mannosylated lipoarabinomannans inhibit IL-12 production by human dendritic cells: evidence for a negative signal delivered through the mannose receptor. J Immunol (2001) 2.20

Immunohistochemical localization of interleukin-6 and its receptor in benign, premalignant and malignant prostate tissue. J Pathol (2000) 2.11

Prostate cancer mortality after introduction of prostate-specific antigen mass screening in the Federal State of Tyrol, Austria. Urology (2001) 2.10

Evaluation and management of renal injuries: consensus statement of the renal trauma subcommittee. BJU Int (2004) 2.09

Interleukin-6 regulates prostate-specific protein expression in prostate carcinoma cells by activation of the androgen receptor. Cancer Res (1998) 2.07

Urinary incontinence in the elderly and age-dependent apoptosis of rhabdosphincter cells. Lancet (1999) 1.92

Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone. Mol Endocrinol (1993) 1.73

Androgen receptors in prostate cancer. Endocr Relat Cancer (2002) 1.71

New onset hypertension after extracorporeal shock wave lithotripsy: age related incidence and prediction by intrarenal resistive index. J Urol (1997) 1.70

Distant metastases from prostatic carcinoma express androgen receptor protein. Cancer Res (1995) 1.63

Neobladder emptying failure in males: incidence, etiology and therapeutic options. J Urol (2006) 1.61

Urethra-sparing cystectomy and orthotopic urinary diversion in women with malignant pelvic tumors. Cancer (2001) 1.58

Rapid signalling by androgen receptor in prostate cancer cells. Oncogene (1999) 1.54

Testicular torsion: late results with special regard to fertility and endocrine function. J Urol (1980) 1.52

Metastatic lesions from prostate cancer do not express oestrogen and progesterone receptors. J Pathol (1997) 1.52

Sildenafil modulates hemodynamics and pulmonary gas exchange. Am J Respir Crit Care Med (2001) 1.50

Laparoscopic surgery for pheochromocytoma: adrenalectomy, partial resection, excision of paragangliomas. J Urol (1998) 1.47

Genes differentially expressed in prostate cancer. BJU Int (2004) 1.45

Zoledronic acid influences growth, migration and invasive activity of prostate cancer cells in vitro. Prostate Cancer Prostatic Dis (2012) 1.43

Regulation of prostatic growth and function by peptide growth factors. Prostate (1996) 1.42

Lich-Gregoir reimplantation causes less discomfort than Politano-Leadbetter technique: Results of a prospective, randomized, pain scale-oriented study in a pediatric population. Eur Urol (2005) 1.39

Extracorporeal shock wave lithotripsy versus ureteroscopy for distal ureteral calculi: a prospective randomized study. J Urol (1999) 1.33

Phenotypic and functional characterization of CD11c+ dendritic cell population in mouse Peyer's patches. Eur J Immunol (1996) 1.33

Expression of 7F7-antigen, a human adhesion molecule identical to intercellular adhesion molecule-1 (ICAM-1) in human carcinomas and their stromal fibroblasts. Int J Cancer (1989) 1.31

HIV-1 gp41 contains two sites for interaction with several proteins on the helper T-lymphoid cell line, H9. AIDS (1992) 1.29

The primary structure of human ribonuclease/angiogenin inhibitor (RAI) discloses a novel highly diversified protein superfamily with a common repetitive module. EMBO J (1988) 1.26

Androgen receptor--an update of mechanisms of action in prostate cancer. Urol Res (2000) 1.25

Age, prostate-specific antigen, and digital rectal examination as determinants of the probability of having prostate cancer. Urology (2001) 1.24

Exocytotic exposure and retrieval of membrane antigens of chromaffin granules: quantitative evaluation of immunofluorescence on the surface of chromaffin cells. J Cell Biol (1984) 1.24

A monoclonal antibody against a surface antigen shared by human large granular lymphocytes and granulocytes. J Immunol (1982) 1.24

The female urethral sphincter: a morphological and topographical study. J Urol (1998) 1.24

Laparoscopic retroperitoneal lymph node dissection for clinical stage I nonseminomatous testicular carcinoma: long-term outcome. J Urol (2000) 1.24

Radical prostatectomy: the value of preoperative, individually labeled apical biopsies. J Urol (2000) 1.23

Inhibition of LncaP prostate cancer cells by means of androgen receptor antisense oligonucleotides. Cancer Gene Ther (2000) 1.21

The phosphatidyl-myo-inositol anchor of the lipoarabinomannans from Mycobacterium bovis bacillus Calmette Guérin. Heterogeneity, structure, and role in the regulation of cytokine secretion. J Biol Chem (1997) 1.21

Cellular and humoral immune responses in patients with metastatic renal cell carcinoma after vaccination with antigen pulsed dendritic cells. J Urol (1999) 1.20

Treatment of giant ancient pelvic schwannoma. Tech Urol (2001) 1.20

Activation of PDGF receptor alpha in vascular smooth muscle cells by mechanical stress. FASEB J (1998) 1.20

Expression, structure, and function of androgen receptor in advanced prostatic carcinoma. Prostate (1998) 1.19

Posttraumatic posterior urethral stricture repair: anatomy, surgical approach and long-term results. J Urol (1997) 1.19

Bacillus Calmette-Guérin mycobacteria stimulate human blood dendritic cells. Int J Cancer (1997) 1.19

Guidelines for the diagnosis and treatment of benign prostatic hyperplasia: a comparative, international overview. Urology (2001) 1.18

Laparoscopic nephron sparing surgery for small renal cell carcinoma. J Urol (1998) 1.17

Prospective comparison and 1-year follow-up of a single endoscopic subureteral polydimethylsiloxane versus dextranomer/hyaluronic acid copolymer injection for treatment of vesicoureteral reflux in children. Urology (2002) 1.16

Androgen receptor status of lymph node metastases from prostate cancer. Prostate (1996) 1.16

Androgen receptor-Ets protein interaction is a novel mechanism for steroid hormone-mediated down-modulation of matrix metalloproteinase expression. J Biol Chem (1996) 1.16

Crossing vessels at the ureteropelvic junction: detection with contrast-enhanced color Doppler imaging. Radiology (1999) 1.16

Epidermal growth factor (EGF) receptor blockade inhibits the action of EGF, insulin-like growth factor I, and a protein kinase A activator on the mitogen-activated protein kinase pathway in prostate cancer cell lines. Cancer Res (1999) 1.14

Prostate cancer cells (LNCaP) generated after long-term interleukin 6 (IL-6) treatment express IL-6 and acquire an IL-6 partially resistant phenotype. Clin Cancer Res (2001) 1.13

Transurethral prostatectomy: mortality and morbidity. Prostate (1996) 1.13

Dihydrotestosterone and the concept of 5alpha-reductase inhibition in human benign prostatic hyperplasia. World J Urol (2002) 1.13

Dihydrotestosterone and the concept of 5alpha-reductase inhibition in human benign prostatic hyperplasia. Eur Urol (2000) 1.12

Vascular endothelial growth factor and its correlation with angiogenesis and p53 expression in prostate cancer. Prostate (2000) 1.12

Distinct ERG rearrangement prevalence in prostate cancer: higher frequency in young age and in low PSA prostate cancer. Prostate Cancer Prostatic Dis (2013) 1.11

Galactosyltransferase and sialyltransferase are located in different subcellular compartments in HeLa cells. Exp Cell Res (1987) 1.11

Light microscopic stereological analysis of the normal human prostate and of benign prostatic hyperplasia. J Urol (1979) 1.08

Identification of syntenin as a protein of the apical early endocytic compartment in Madin-Darby canine kidney cells. J Biol Chem (1999) 1.08

Isolated right-sided varicocele as a salvage pathway for portal hypertension. Int J Clin Pract (2005) 1.08

Primary lymphatic metastatic spread in testicular cancer occurs ventral to the lumbar vessels. Urology (2002) 1.07

Morphometry in experimental pathology: methods, baseline data and applications. Int Rev Exp Pathol (1976) 1.07

Comparison of contrast enhanced color Doppler targeted biopsy to conventional systematic biopsy: impact on Gleason score. J Urol (2007) 1.07

Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer. Prostate Cancer Prostatic Dis (2004) 1.07

Laparoscopic partial adrenalectomy in patients with aldosterone-producing adenomas: indications, technique, and results. Urology (2003) 1.06

Transforming growth factors-beta 1 and beta 2 in serum and urine from patients with bladder carcinoma. J Urol (1996) 1.05

Orgotein: a new antiinflammatory metalloprotein drug evaluation of clinical efficacy and safety in inflammatory conditions of the urinary tract. Int Urol Nephrol (1974) 1.04

Promotion of lymphocyte growth by high density lipoproteins (HDL). Physiological significance of the HDL binding site. J Biol Chem (1989) 1.04

Mechanisms of endocrine therapy-responsive and -unresponsive prostate tumours. Endocr Relat Cancer (2005) 1.02

High amount of epsilon-(gamma-glutamyl)lysine cross-links in Mallory bodies. Lab Invest (1992) 1.02

Cyclin D3 and c-MYC control glucocorticoid-induced cell cycle arrest but not apoptosis in lymphoblastic leukemia cells. Cell Death Differ (2004) 1.01

DNA sequence of the androgen receptor in prostatic tumor cell lines and tissue specimens assessed by means of the polymerase chain reaction. Prostate (1993) 1.01