Published in Cancer on October 15, 1997
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment. Proc Natl Acad Sci U S A (2001) 7.99
Isolation by size of epithelial tumor cells : a new method for the immunomorphological and molecular characterization of circulatingtumor cells. Am J Pathol (2000) 5.26
Preparing the "soil": the premetastatic niche. Cancer Res (2006) 2.92
L-selectin can facilitate metastasis to lymph nodes in a transgenic mouse model of carcinogenesis. Proc Natl Acad Sci U S A (2001) 2.01
Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation. Genes Dev (2008) 2.00
Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer. Br J Cancer (2010) 1.96
Activated leukocyte cell adhesion molecule/CD166, a marker of tumor progression in primary malignant melanoma of the skin. Am J Pathol (2000) 1.93
A "class action" against the microenvironment: do cancer cells cooperate in metastasis? Cancer Metastasis Rev (2008) 1.91
The tumor microenvironment and metastatic disease. Clin Exp Metastasis (2008) 1.91
Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells. PLoS One (2009) 1.87
Platelet glycoprotein Ib alpha supports experimental lung metastasis. Proc Natl Acad Sci U S A (2007) 1.68
Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis. Proc Natl Acad Sci U S A (2000) 1.64
Role of mTOR signaling in tumor cell motility, invasion and metastasis. Curr Protein Pept Sci (2011) 1.37
Matrix metalloproteases in head and neck cancer. Head Neck (2006) 1.35
Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway. J Exp Clin Cancer Res (2010) 1.32
Biological properties and gene expression associated with metastatic potential of human osteosarcoma. Clin Exp Metastasis (2003) 1.32
Role of the integrin-binding protein osteopontin in lymphatic metastasis of breast cancer. Am J Pathol (2006) 1.30
Blockade of the RhoA-JNK-c-Jun-MMP2 cascade by atorvastatin reduces osteosarcoma cell invasion. J Biol Chem (2008) 1.29
Selectins and selectin ligands in extravasation of cancer cells and organ selectivity of metastasis. Clin Exp Metastasis (2007) 1.29
EMT and tumor metastasis. Clin Transl Med (2015) 1.29
Circulating tumor cell analysis: technical and statistical considerations for application to the clinic. J Oncol (2009) 1.26
A novel circular invasion assay mimics in vivo invasive behavior of cancer cell lines and distinguishes single-cell motility in vitro. BMC Cancer (2008) 1.21
Loss of miR-133a expression associated with poor survival of breast cancer and restoration of miR-133a expression inhibited breast cancer cell growth and invasion. BMC Cancer (2012) 1.20
Relationship between phenotypes of cell-function differentiation and pathobiological behavior of gastric carcinomas. World J Gastroenterol (2001) 1.17
The role of immunoglobulin superfamily cell adhesion molecules in cancer metastasis. Int J Cell Biol (2012) 1.15
mTOR signaling in cancer cell motility and tumor metastasis. Crit Rev Eukaryot Gene Expr (2010) 1.13
Collapsin response mediator protein-1: a novel invasion-suppressor gene. Clin Exp Metastasis (2003) 1.12
Beta-catenin mediates alteration in cell proliferation, motility and invasion of prostate cancer cells by differential expression of E-cadherin and protein kinase D1. J Cell Biochem (2008) 1.11
Engineered production of iso-migrastatin in heterologous Streptomyces hosts. Bioorg Med Chem (2008) 1.11
Fascin is a key regulator of breast cancer invasion that acts via the modification of metastasis-associated molecules. PLoS One (2011) 1.10
Cyclooxygenase-2 selective inhibition with NS-398 suppresses proliferation and invasiveness and delays liver metastasis in colorectal cancer. Br J Cancer (2004) 1.10
iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase. J Biol Chem (2009) 1.08
Claudin-1 acts through c-Abl-protein kinase Cdelta (PKCdelta) signaling and has a causal role in the acquisition of invasive capacity in human liver cells. J Biol Chem (2009) 1.07
Vascular endothelial platelet endothelial cell adhesion molecule 1 (PECAM-1) regulates advanced metastatic progression. Proc Natl Acad Sci U S A (2010) 1.07
β-arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix. Sci Transl Med (2011) 1.06
S100A4 (Mts1) gene overexpression is associated with invasion and metastasis of papillary thyroid carcinoma. Br J Cancer (2005) 1.05
The tumor cell-host organ interface in the early onset of metastatic organ colonisation. Clin Exp Metastasis (2007) 1.04
Survivin is a potential mediator of prostate cancer metastasis. Int J Radiat Oncol Biol Phys (2010) 1.04
Prognostic significance of MCM2, Ki-67 and gelsolin in non-small cell lung cancer. BMC Cancer (2006) 1.03
Prognostic impact of EMT (epithelial-mesenchymal-transition)-related protein expression in endometrial cancer. Cancer Biol Ther (2012) 1.03
Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo. Br J Cancer (2007) 1.03
Novel INTeraction of MUC4 and galectin: potential pathobiological implications for metastasis in lethal pancreatic cancer. Clin Cancer Res (2010) 1.03
Substrate recognition by gelatinase A: the C-terminal domain facilitates surface diffusion. Biophys J (2001) 1.01
Establishment and characterization of human osteosarcoma cell lines with different pulmonary metastatic potentials. Cytotechnology (2009) 1.01
CCL5 and CCR5 interaction promotes cell motility in human osteosarcoma. PLoS One (2012) 1.00
S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells. Clin Exp Metastasis (2003) 0.98
Galectin-3 in angiogenesis and metastasis. Glycobiology (2014) 0.97
Plumbagin inhibits osteoclastogenesis and reduces human breast cancer-induced osteolytic bone metastasis in mice through suppression of RANKL signaling. Mol Cancer Ther (2011) 0.97
Invasion of normal human fibroblasts induced by v-Fos is independent of proliferation, immortalization, and the tumor suppressors p16INK4a and p53. Mol Cell Biol (2004) 0.97
Spatial heterogeneity in drug concentrations can facilitate the emergence of resistance to cancer therapy. PLoS Comput Biol (2015) 0.96
Thermolysis of isomigrastatin and its congeners via [3,3]-sigmatropic rearrangement: a new route to the synthesis of migrastatin and its analogues. Org Lett (2006) 0.95
Immunofluorometric quantitation and histochemical localisation of kallikrein 6 protein in ovarian cancer tissue: a new independent unfavourable prognostic biomarker. Br J Cancer (2002) 0.95
IL-6 increases MMP-13 expression and motility in human chondrosarcoma cells. J Biol Chem (2011) 0.95
High calcium concentration in bones promotes bone metastasis in renal cell carcinomas expressing calcium-sensing receptor. Mol Cancer (2014) 0.94
Detection of cancer before distant metastasis. BMC Cancer (2013) 0.94
Identification of annexin A1 as a proinvasive and prognostic factor for lung adenocarcinoma. Clin Exp Metastasis (2011) 0.92
HGF and c-Met interaction promotes migration in human chondrosarcoma cells. PLoS One (2013) 0.92
Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion. Oncotarget (2015) 0.91
Interactions between microenvironment and cancer cells in two animal models of bone metastasis. Br J Cancer (2008) 0.90
C-X-C motif chemokine 12/C-X-C chemokine receptor type 7 signaling regulates breast cancer growth and metastasis by modulating the tumor microenvironment. Breast Cancer Res (2014) 0.90
Cooperation of cancer stem cell properties and epithelial-mesenchymal transition in the establishment of breast cancer metastasis. J Oncol (2010) 0.90
Rat models of bone metastases. Clin Exp Metastasis (2006) 0.90
Secretomic analysis identifies alpha-1 antitrypsin (A1AT) as a required protein in cancer cell migration, invasion, and pericellular fibronectin assembly for facilitating lung colonization of lung adenocarcinoma cells. Mol Cell Proteomics (2012) 0.89
Concise syntheses of the abyssinones and discovery of new inhibitors of prostate cancer and MMP-2 expression. ACS Med Chem Lett (2010) 0.89
beta(3)A-integrin downregulates the urokinase-type plasminogen activator receptor (u-PAR) through a PEA3/ets transcriptional silencing element in the u-PAR promoter. Mol Cell Biol (2001) 0.88
Cellular migration and invasion uncoupled: increased migration is not an inexorable consequence of epithelial-to-mesenchymal transition. Mol Cell Biol (2014) 0.88
PTCSC3 Is Involved in Papillary Thyroid Carcinoma Development by Modulating S100A4 Gene Expression. J Clin Endocrinol Metab (2015) 0.88
Growth factors in tumor microenvironment. Front Biosci (Landmark Ed) (2010) 0.88
Olfactomedin 4 suppresses tumor growth and metastasis of mouse melanoma cells through downregulation of integrin and MMP genes. Mol Cells (2012) 0.88
Drosophila brain tumor metastases express both neuronal and glial cell type markers. Dev Biol (2006) 0.87
Gene expression patterns related to vascular invasion and aggressive features in endometrial cancer. Am J Pathol (2011) 0.87
The effect of hyaluronic Acid on the invasiveness of malignant glioma cells : comparison of invasion potential at hyaluronic Acid hydrogel and matrigel. J Korean Neurosurg Soc (2009) 0.86
Small but mighty: microparticles as mediators of tumor progression. Cancer Microenviron (2014) 0.86
Gain in cellular organization of inflammatory breast cancer: A 3D in vitro model that mimics the in vivo metastasis. BMC Cancer (2009) 0.86
Expression of matrix metalloproteinases and their inhibitors in squamous cell carcinoma of the tonsil and their clinical significance. Clin Exp Otorhinolaryngol (2011) 0.85
Inhibition of AP-1 transcriptional activity blocks the migration, invasion, and experimental metastasis of murine osteosarcoma. Am J Pathol (2008) 0.85
Modulation of glioma cell invasion and motility by adenoviral gene transfer of PAI-1. Clin Exp Metastasis (2003) 0.84
Hypochlorite-induced oxidative stress elevates the capability of HDL in promoting breast cancer metastasis. J Transl Med (2012) 0.84
Multiple effects of electroporation on the adhesive behaviour of breast cancer cells and fibroblasts. Cancer Cell Int (2012) 0.83
Marine bromophenol bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane inhibits the proliferation, migration, and invasion of hepatocellular carcinoma cells via modulating β1-integrin/FAK signaling. Mar Drugs (2015) 0.83
AEG-1 promotes anoikis resistance and orientation chemotaxis in hepatocellular carcinoma cells. PLoS One (2014) 0.83
Heat shock protein 27 regulates human prostate cancer cell motility and metastatic progression. Oncotarget (2014) 0.83
Suppression of thymosin β10 increases cell migration and metastasis of cholangiocarcinoma. BMC Cancer (2013) 0.82
Carcinoid tumours: predicting the location of the primary neoplasm based on the sites of metastases. Eur Radiol (2012) 0.82
Granzyme M expressed by tumor cells promotes chemoresistance and EMT in vitro and metastasis in vivo associated with STAT3 activation. Oncotarget (2015) 0.82
Hypoxia-induced changes to integrin α 3 glycosylation facilitate invasion in epidermoid carcinoma cell line A431. Mol Cell Proteomics (2014) 0.82
Application of conditional probability analysis to distant metastases from lung cancer. Oncol Lett (2011) 0.82
HspBP1 levels are elevated in breast tumor tissue and inversely related to tumor aggressiveness. Cell Stress Chaperones (2008) 0.81
(±)Equol inhibits invasion in prostate cancer DU145 cells possibly via down-regulation of matrix metalloproteinase-9, matrix metalloproteinase-2 and urokinase-type plasminogen activator by antioxidant activity. J Clin Biochem Nutr (2012) 0.81
βig-h3 promotes human osteosarcoma cells metastasis by interacting with integrin α2β1 and activating PI3K signaling pathway. PLoS One (2014) 0.81
Cassia tora L. (Jue-ming-zi) has anticancer activity in TCA8113 cells in vitro and exerts anti-metastatic effects in vivo. Oncol Lett (2012) 0.80
Capsosiphon fulvescens glycoprotein reduces AGS gastric cancer cell migration by downregulating transforming growth factor-β1 and integrin expression. Int J Oncol (2013) 0.80
Photoacoustic imaging: a potential tool to detect early indicators of metastasis. Expert Rev Med Devices (2013) 0.80
Expression of Lipid Metabolism-Related Proteins in Metastatic Breast Cancer. PLoS One (2015) 0.80
RhoA regulates invasion of glioma cells via the c-Jun NH2-terminal kinase pathway under hypoxia. Oncol Lett (2012) 0.79
Tertiary structure prediction and identification of druggable pocket in the cancer biomarker - Osteopontin-c. J Diabetes Metab Disord (2014) 0.79
Marker-free phenotyping of tumor cells by fractal analysis of reflection interference contrast microscopy images. Nano Lett (2013) 0.79
Cathepsin G induces cell aggregation of human breast cancer MCF-7 cells via a 2-step mechanism: catalytic site-independent binding to the cell surface and enzymatic activity-dependent induction of the cell aggregation. Mediators Inflamm (2012) 0.79
Palladin regulation of the actin structures needed for cancer invasion. Cell Adh Migr (2013) 0.79
Novel enantiopure cyclopentadienyl Ti(IV) oximato compounds as potential anticancer agents. J Inorg Biochem (2015) 0.79
Laser capture microdissection. Science (1996) 12.21
Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci U S A (1986) 12.14
Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science (1997) 7.95
Isolation and characterization of type IV procollagen, laminin, and heparan sulfate proteoglycan from the EHS sarcoma. Biochemistry (1982) 6.87
Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu Rev Cell Biol (1993) 6.53
Metastatic potential correlates with enzymatic degradation of basement membrane collagen. Nature (1980) 5.84
Evidence for a novel gene associated with low tumor metastatic potential. J Natl Cancer Inst (1988) 5.42
Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture. Cancer Res (1986) 5.05
Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front. Oncogene (2001) 4.40
Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation. Cancer Res (1974) 3.96
Laser capture microdissection: molecular analysis of tissue. Science (1997) 3.93
Tumor invasion and the extracellular matrix. Lab Invest (1983) 3.81
Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development. Nature (1989) 3.75
High-resolution serum proteomic features for ovarian cancer detection. Endocr Relat Cancer (2004) 3.75
The significance of hematogenous tumor cell clumps in the metastatic process. Cancer Res (1976) 3.47
Laminin receptor on human breast carcinoma cells. Proc Natl Acad Sci U S A (1983) 3.32
Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells. Cell (1991) 3.21
Altered levels of laminin receptor mRNA in various human carcinoma cells that have different abilities to bind laminin. Proc Natl Acad Sci U S A (1986) 3.21
Biochemical interactions of tumor cells with the basement membrane. Annu Rev Biochem (1986) 3.06
Isolation of a tumor cell laminin receptor. Biochem Biophys Res Commun (1983) 3.05
Effect of plasminogen activator (urokinase), plasmin, and thrombin on glycoprotein and collagenous components of basement membrane. Cancer Res (1981) 3.00
Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein. J Biol Chem (1992) 2.93
Tissue inhibitor of metalloproteinase (TIMP-2). A new member of the metalloproteinase inhibitor family. J Biol Chem (1989) 2.87
Detection of gene deletion in single metastatic tumour cells in lymphnode tissue by fluorescent in-situ hybridisation. Lancet (1997) 2.77
Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: a potential angiogenesis regulatory factor. J Cell Biol (1990) 2.69
Laser-capture microdissection: opening the microscopic frontier to molecular analysis. Trends Genet (1998) 2.60
Immuno-LCM: laser capture microdissection of immunostained frozen sections for mRNA analysis. Am J Pathol (1999) 2.59
A microdissection technique for archival DNA analysis of specific cell populations in lesions < 1 mm in size. Am J Pathol (1995) 2.59
Molecular insights into cancer invasion: strategies for prevention and intervention. Cancer Res (1995) 2.50
Role of laminin in the attachment and metastasis of murine tumor cells. Cancer Res (1982) 2.49
Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines. Cancer Res (1990) 2.40
Association of low nm23 RNA levels in human primary infiltrating ductal breast carcinomas with lymph node involvement and other histopathological indicators of high metastatic potential. Cancer Res (1989) 2.39
A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase. Cell (1990) 2.36
Tumor cell autocrine motility factor. Proc Natl Acad Sci U S A (1986) 2.28
Extracellular matrix 6: role of matrix metalloproteinases in tumor invasion and metastasis. FASEB J (1993) 2.28
Preferential digestion of basement membrane collagen by an enzyme derived from a metastatic murine tumor. Proc Natl Acad Sci U S A (1979) 2.25
Molecular aspects of tumor cell invasion and metastasis. Cancer (1993) 2.24
Molecular mediators of interactions with extracellular matrix components in metastasis and angiogenesis. Curr Opin Oncol (1994) 2.21
Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia. Am J Pathol (1992) 2.17
Tumor cell invasion inhibited by TIMP-2. J Natl Cancer Inst (1991) 2.15
Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues. J Biol Chem (1990) 1.98
Loss of basement membrane components by invasive tumors but not by their benign counterparts. Lab Invest (1983) 1.91
Somatic mutation of the MEN1 gene in parathyroid tumours. Nat Genet (1997) 1.90
Signal transduction for chemotaxis and haptotaxis by matrix molecules in tumor cells. J Cell Biol (1990) 1.89
Allelic loss on chromosome 8p12-21 in microdissected prostatic intraepithelial neoplasia. Cancer Res (1995) 1.85
Isolation of a subunit of laminin and its role in molecular structure and tumor cell attachment. J Biol Chem (1982) 1.84
Immunohistochemical distribution of type IV collagenase in normal, benign, and malignant breast tissue. Am J Pathol (1990) 1.82
A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus. Genome Res (1997) 1.82
Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma. Clin Cancer Res (2000) 1.81
Evidence of independent origin of multiple tumors from patients with prostate cancer. J Natl Cancer Inst (1998) 1.81
Multiple endocrine neoplasia type 1: clinical and genetic topics. Ann Intern Med (1998) 1.81
The activation of human type IV collagenase proenzyme. Sequence identification of the major conversion product following organomercurial activation. J Biol Chem (1989) 1.80
Evidence for a precursor of the high-affinity metastasis-associated murine laminin receptor. Biochemistry (1989) 1.80
Tumor invasion and metastases: role of the basement membrane. Warner-Lambert Parke-Davis Award lecture. Am J Pathol (1984) 1.79
Effects of inhibition of basement membrane collagen deposition on rat mammary gland development. Dev Biol (1980) 1.79
Analysis of 99 microdissected prostate carcinomas reveals a high frequency of allelic loss on chromosome 8p12-21. Cancer Res (1996) 1.78
Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related states. Hum Mol Genet (1997) 1.77
Altered expression of NM23, a gene associated with low tumor metastatic potential, during adenovirus 2 Ela inhibition of experimental metastasis. Cancer Res (1988) 1.75
Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor. Cancer Res (2001) 1.73
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung. Hum Mol Genet (1997) 1.70
Differential response to growth factor by rat mammary epithelium plated on different collagen substrata in serum-free medium. Proc Natl Acad Sci U S A (1981) 1.69
Basement membrane collagen: degradation by migrating endothelial cells. Science (1983) 1.67
Proteomic patterns of nipple aspirate fluids obtained by SELDI-TOF: potential for new biomarkers to aid in the diagnosis of breast cancer. Dis Markers (2001) 1.67
Galectin-3 is a novel substrate for human matrix metalloproteinases-2 and -9. Biochemistry (1994) 1.63
Transient expression of type IV collagenolytic metalloproteinase by human mononuclear phagocytes. J Biol Chem (1986) 1.62
Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells. Oncogene (2000) 1.60
Increased content of Type V Collagen in desmoplasia of human breast carcinoma. Am J Pathol (1982) 1.59
Role of laminin receptor in tumor cell migration. Cancer Res (1987) 1.58
Identical allelic loss on chromosome 11q13 in microdissected in situ and invasive human breast cancer. Cancer Res (1995) 1.57
Interactions of basement membrane components. Biochim Biophys Acta (1983) 1.57
Thrombospondin-induced tumor cell migration: haptotaxis and chemotaxis are mediated by different molecular domains. J Cell Biol (1987) 1.56
Immunohistochemical study of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in pulmonary lymphangioleiomyomatosis (LAM). Hum Pathol (1997) 1.53
Formation of metastasis by human breast carcinoma cells (MCF-7) in nude mice. Cancer Lett (1980) 1.52
Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma. Cancer Res (1991) 1.52
Basement membrane collagen requirements for attachment and growth of mammary epithelium. Exp Cell Res (1979) 1.52
Loss of annexin 1 correlates with early onset of tumorigenesis in esophageal and prostate carcinoma. Cancer Res (2000) 1.50
Immunodetection of the metastasis-associated laminin receptor in human breast cancer cells obtained by fine-needle aspiration biopsy. Am J Pathol (1990) 1.49
Partial purification and characterization of a neutral protease which cleaves type IV collagen. Biochemistry (1981) 1.49
NIH/3T3 cells transfected with human tumor DNA containing activated ras oncogenes express the metastatic phenotype in nude mice. Mol Cell Biol (1985) 1.48
CAIR-1/BAG-3 forms an EGF-regulated ternary complex with phospholipase C-gamma and Hsp70/Hsc70. Oncogene (2000) 1.47
New method for preparing large surfaces of intact human basement membrane for tumor invasion studies. Cancer Lett (1980) 1.47
cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases. J Biol Chem (1994) 1.46
Purification and characterization of a murine basement membrane collagen-degrading enzyme secreted by metastatic tumor cells. J Biol Chem (1983) 1.45
Low nm23 protein expression in infiltrating ductal breast carcinomas correlates with reduced patient survival. Am J Pathol (1991) 1.45
Degradation of basement membrane by murine tumor cells. J Natl Cancer Inst (1977) 1.45
Autotaxin is an exoenzyme possessing 5'-nucleotide phosphodiesterase/ATP pyrophosphatase and ATPase activities. J Biol Chem (1997) 1.44
Effects of free fatty acids on the growth of normal and neoplastic rat mammary epithelial cells. Cancer Res (1979) 1.44
Laminin molecular domains which alter metastasis in a murine model. J Clin Invest (1984) 1.43
Modulation of the metastatic activity of melanoma cells by laminin and fibronectin. Science (1984) 1.42
Domain structure of human 72-kDa gelatinase/type IV collagenase. Characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinase-2 (TIMP-2) binding regions. J Biol Chem (1992) 1.40
Immunohistochemical study of metalloproteinases and their tissue inhibitors in the lungs of patients with diffuse alveolar damage and idiopathic pulmonary fibrosis. Am J Pathol (1996) 1.40
Augmentation of type IV collagenase, laminin receptor, and Ki67 proliferation antigen associated with human colon, gastric, and breast carcinoma progression. Mod Pathol (1991) 1.39
Necropsy as a research method in the age of molecular pathology. Lancet (1995) 1.37
Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples. Am J Pathol (1994) 1.36
Integrin alphavbeta3 mediates chemotactic and haptotactic motility in human melanoma cells through different signaling pathways. J Biol Chem (1996) 1.34
Proteolytic enzymes in cancer invasion and metastasis. Semin Thromb Hemost (1986) 1.34
Spatiotemporal segregation of endothelial cell integrin and nonintegrin extracellular matrix-binding proteins during adhesion events. J Cell Biol (1990) 1.32
Role of collagenases in tumor cell invasion. Cancer Metastasis Rev (1982) 1.32