Published in EMBO J on November 17, 1997
Mechanism of chromosome compaction and looping by the Escherichia coli nucleoid protein Fis. J Mol Biol (2006) 1.73
The shape of the DNA minor groove directs binding by the DNA-bending protein Fis. Genes Dev (2010) 1.55
Mutants of Tn3 resolvase which do not require accessory binding sites for recombination activity. EMBO J (1999) 1.38
Functional characterization of the Escherichia coli Fis-DNA binding sequence. J Mol Biol (2007) 1.12
Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding. EMBO J (1998) 1.09
Fis targets assembly of the Xis nucleoprotein filament to promote excisive recombination by phage lambda. J Mol Biol (2007) 1.06
Fis is essential for capsule production in Pasteurella multocida and regulates expression of other important virulence factors. PLoS Pathog (2010) 1.03
Communication between Hin recombinase and Fis regulatory subunits during coordinate activation of Hin-catalyzed site-specific DNA inversion. Genes Dev (1998) 1.02
Identification and characterization of the fis operon in enteric bacteria. J Bacteriol (1998) 1.01
Conversion of a beta-strand to an alpha-helix induced by a single-site mutation observed in the crystal structure of Fis mutant Pro26Ala. Protein Sci (1998) 0.97
Mechanical constraints on Hin subunit rotation imposed by the Fis/enhancer system and DNA supercoiling during site-specific recombination. Mol Cell (2009) 0.95
Equilibrium denaturation studies of the Escherichia coli factor for inversion stimulation: implications for in vivo function. Protein Sci (2002) 0.93
Modeling helix-turn-helix protein-induced DNA bending with knowledge-based distance restraints. Biophys J (1999) 0.92
Common and variable contributions of Fis residues to high-affinity binding at different DNA sequences. J Bacteriol (2006) 0.90
Secondary structure and DNA binding by the C-terminal domain of the transcriptional activator NifA from Klebsiella pneumoniae. Nucleic Acids Res (2002) 0.87
Biochemical identification of base and phosphate contacts between Fis and a high-affinity DNA binding site. J Mol Biol (2008) 0.84
Multiple interfaces between a serine recombinase and an enhancer control site-specific DNA inversion. Elife (2013) 0.84
Electrostatics, structure prediction, and the energy landscapes for protein folding and binding. Protein Sci (2015) 0.83
Site-specific DNA Inversion by Serine Recombinases. Microbiol Spectr (2015) 0.82
Intrasubunit and intersubunit interactions controlling assembly of active synaptic complexes during Hin-catalyzed DNA recombination. J Mol Biol (2011) 0.82
In vivo assay of protein-protein interactions in Hin-mediated DNA inversion. J Bacteriol (1998) 0.82
Effect of DNA superhelicity and bound proteins on mechanistic aspects of the Hin-mediated and Fis-enhanced inversion. Biophys J (2003) 0.78
Controlled rotation mechanism of DNA strand exchange by the Hin serine recombinase. Sci Rep (2016) 0.75
Raster3D Version 2.0. A program for photorealistic molecular graphics. Acta Crystallogr D Biol Crystallogr (1994) 17.44
The locus of sequence-directed and protein-induced DNA bending. Nature (1984) 15.05
A general method for rapid site-directed mutagenesis using the polymerase chain reaction. Gene (1990) 8.36
Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science (1992) 7.00
Crystal structure of an IHF-DNA complex: a protein-induced DNA U-turn. Cell (1996) 5.38
Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A. Science (1996) 5.19
Antibody-antigen complexes. Annu Rev Biochem (1990) 3.91
Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain. Cell (1996) 3.88
Host protein requirements for in vitro site-specific DNA inversion. Cell (1986) 3.31
3-A resolution structure of a protein with histone-like properties in prokaryotes. Nature (1984) 2.92
Conformation of beta-hairpins in protein structures. A systematic classification with applications to modelling by homology, electron density fitting and protein engineering. J Mol Biol (1989) 2.86
Purification and properties of the Escherichia coli host factor required for inversion of the G segment in bacteriophage Mu. J Biol Chem (1986) 2.75
The refined 2.4 A X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction. EMBO J (1990) 2.44
Crystal structure at 2.2 A resolution of the pleckstrin homology domain from human dynamin. Cell (1994) 2.41
Efficient excision of phage lambda from the Escherichia coli chromosome requires the Fis protein. J Bacteriol (1991) 2.16
The Hin invertasome: protein-mediated joining of distant recombination sites at the enhancer. Science (1990) 2.06
Three-dimensional structure of the E. coli DNA-binding protein FIS. Nature (1991) 2.01
Identification of two functional regions in Fis: the N-terminus is required to promote Hin-mediated DNA inversion but not lambda excision. EMBO J (1991) 1.97
The molecular structure of wild-type and a mutant Fis protein: relationship between mutational changes and recombinational enhancer function or DNA binding. Proc Natl Acad Sci U S A (1991) 1.93
Isolation and characterization of unusual gin mutants. EMBO J (1988) 1.87
Variable structures of Fis-DNA complexes determined by flanking DNA-protein contacts. J Mol Biol (1996) 1.74
Gin-mediated DNA inversion: product structure and the mechanism of strand exchange. Proc Natl Acad Sci U S A (1988) 1.72
Intermediates in Hin-mediated DNA inversion: a role for Fis and the recombinational enhancer in the strand exchange reaction. EMBO J (1989) 1.67
Fis activates the RpoS-dependent stationary-phase expression of proP in Escherichia coli. J Bacteriol (1995) 1.46
Processive recombination by wild-type gin and an enhancer-independent mutant. Insight into the mechanisms of recombination selectivity and strand exchange. J Mol Biol (1994) 1.45
DNA binding and bending are necessary but not sufficient for Fis-dependent activation of rrnB P1. J Bacteriol (1993) 1.43
The N-terminal part of the E.coli DNA binding protein FIS is essential for stimulating site-specific DNA inversion but is not required for specific DNA binding. Nucleic Acids Res (1991) 1.38
Configuration of DNA strands and mechanism of strand exchange in the Hin invertasome as revealed by analysis of recombinant knots. Genes Dev (1991) 1.32
Enhancer-independent mutants of the Cin recombinase have a relaxed topological specificity. EMBO J (1988) 1.29
Solution structure of the HU protein from Bacillus stearothermophilus. J Mol Biol (1995) 1.18
Crystal structure of the factor for inversion stimulation FIS at 2.0 A resolution. J Mol Biol (1992) 1.18
The Hin dimer interface is critical for Fis-mediated activation of the catalytic steps of site-specific DNA inversion. Curr Biol (1996) 1.16
Analysis of strand exchange and DNA binding of enhancer-independent Gin recombinase mutants. EMBO J (1993) 1.15
Molecular anatomy of a transcription activation patch: FIS-RNA polymerase interactions at the Escherichia coli rrnB P1 promoter. EMBO J (1997) 1.10
Protein-protein interactions directing resolvase site-specific recombination: a structure-function analysis. EMBO J (1993) 1.10
The structure of Fis mutant Pro61Ala illustrates that the kink within the long alpha-helix is not due to the presence of the proline residue. J Biol Chem (1994) 0.91
A model for Fis N-terminus and Fis-invertase recognition. FEBS Lett (1997) 0.81
Differentiation of pathogenic and saprophytic letospires. I. Growth at low temperatures. J Bacteriol (1967) 8.91
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice. Cell (1993) 6.05
Infection of Syrian hamsters with Lyme disease spirochetes. J Clin Microbiol (1984) 5.40
Isolation of spontaneously derived mutants of Caulobacter crescentus. Genetics (1977) 4.44
Cross-reactivity in serological tests for Lyme disease and other spirochetal infections. J Infect Dis (1987) 3.79
Genetic relationship of lyme disease spirochetes to Borrelia, Treponema, and Leptospira spp. J Clin Microbiol (1984) 3.78
Hin-mediated site-specific recombination requires two 26 bp recombination sites and a 60 bp recombinational enhancer. Cell (1985) 3.69
Generalized Transduction in CAULOBACTER CRESCENTUS. Genetics (1977) 3.62
Immunoblot interpretation criteria for serodiagnosis of early Lyme disease. J Clin Microbiol (1995) 3.59
Dramatic changes in Fis levels upon nutrient upshift in Escherichia coli. J Bacteriol (1992) 3.39
Retention of motility and virulence of Treponema pallidum (Nichols strain) in vitro. Infect Immun (1975) 3.31
Host protein requirements for in vitro site-specific DNA inversion. Cell (1986) 3.31
Identification of endemic foci of Lyme disease: isolation of Borrelia burgdorferi from feral rodents and ticks (Dermacentor variabilis). J Clin Microbiol (1985) 3.17
The Fis protein: it's not just for DNA inversion anymore. Mol Microbiol (1992) 3.02
The nonspecific DNA-binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures. Genes Dev (1993) 3.01
Key role of teichoic acid net charge in Staphylococcus aureus colonization of artificial surfaces. Infect Immun (2001) 2.96
Characterization of the attachment of Treponema pallidum (Nichols strain) to cultured mammalian cells and the potential relationship of attachment to pathogenicity. Infect Immun (1977) 2.95
Analysis of nonmotile mutants of the dimorphic bacterium Caulobacter crescentus. J Bacteriol (1979) 2.75
Control of Tn5 transposition in Escherichia coli is mediated by protein from the right repeat. Cell (1982) 2.74
Selective alteration of personality and social behavior by serotonergic intervention. Am J Psychiatry (1998) 2.69
Effects of bovine serum albumin on the ability of Barbour-Stoenner-Kelly medium to detect Borrelia burgdorferi. J Clin Microbiol (1990) 2.60
Azithromycin compared with amoxicillin in the treatment of erythema migrans. A double-blind, randomized, controlled trial. Ann Intern Med (1996) 2.58
Passive immunization of hamsters against experimental infection with the Lyme disease spirochete. Infect Immun (1986) 2.55
The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis. Neuron (2001) 2.52
Involvement of birds in the epidemiology of the Lyme disease agent Borrelia burgdorferi. Infect Immun (1986) 2.40
Antileptospiral activity of serum. I. Normal and immune serum. J Bacteriol (1966) 2.38
Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin. Proc Natl Acad Sci U S A (1995) 2.37
The persistence of spirochetal nucleic acids in active Lyme arthritis. Ann Intern Med (1994) 2.36
Interaction of Treponema pallidum (Nichols strain) with cultured mammalian cells: effects of oxygen, reducing agents, serum supplements, and different cell types. Infect Immun (1977) 2.33
Isolation of the outer envelope, chemical components, and ultrastructure of Borrelia hermsi grown in vitro. Acta Trop (1979) 2.33
DNA sequences at the ends of transposon Tn5 required for transposition. Nature (1983) 2.32
Coexistence of antibodies to tick-borne pathogens of babesiosis, ehrlichiosis, and Lyme borreliosis in human sera. J Clin Microbiol (1995) 2.32
Surface mucopolysaccharides of Treponema pallidum. Infect Immun (1979) 2.27
Antigenically variable Borrelia burgdorferi isolated from cottontail rabbits and Ixodes dentatus in rural and urban areas. J Clin Microbiol (1989) 2.20
Isolation of the outer sheath of Leptospira and its immunogenic properties in hamsters. Infect Immun (1972) 2.20
Scanning electron microscopy of Treponema pallidum (Nichols strain) attached to cultured mammalian cells. J Bacteriol (1977) 2.19
Genetic organization of Tn5. Cold Spring Harb Symp Quant Biol (1981) 2.18
Treatment of early Lyme disease. Am J Med (1992) 2.18
The histopathology of experimentally infected hamsters with the Lyme disease spirochete, Borrelia burgdorferi. Proc Soc Exp Biol Med (1986) 2.18
The spirochetes. Annu Rev Microbiol (1977) 2.18
Efficient excision of phage lambda from the Escherichia coli chromosome requires the Fis protein. J Bacteriol (1991) 2.16
Cultivation of Borrelia burgdorferi from erythema migrans lesions and perilesional skin. J Clin Microbiol (1992) 2.12
The Hin invertasome: protein-mediated joining of distant recombination sites at the enhancer. Science (1990) 2.06
Spirochetes in ticks and antibodies to Borrelia burgdorferi in white-tailed deer from Connecticut, New York State, and North Carolina. J Wildl Dis (1986) 2.04
Fis binding to the recombinational enhancer of the Hin DNA inversion system. Genes Dev (1987) 2.02
Correlation of plasmids with infectivity of Borrelia burgdorferi sensu stricto type strain B31. Infect Immun (1996) 2.01
In vitro and in vivo susceptibility of the Lyme disease spirochete, Borrelia burgdorferi, to four antimicrobial agents. Antimicrob Agents Chemother (1987) 1.98
Identification of two functional regions in Fis: the N-terminus is required to promote Hin-mediated DNA inversion but not lambda excision. EMBO J (1991) 1.97
Role of immunoglobulin G in killing of Borrelia burgdorferi by the classical complement pathway. Infect Immun (1988) 1.97
A case-control study to assess possible triggers and cofactors in chronic fatigue syndrome. Am J Med (1996) 1.96
Active immunization of hamsters against experimental infection with Borrelia burgdorferi. Infect Immun (1986) 1.94
The molecular structure of wild-type and a mutant Fis protein: relationship between mutational changes and recombinational enhancer function or DNA binding. Proc Natl Acad Sci U S A (1991) 1.93
Antileptospiral activity of serum. II. Leptospiral virulence factor. J Bacteriol (1967) 1.92
The crystal structure of the DNase domain of colicin E7 in complex with its inhibitor Im7 protein. Structure (1999) 1.87
Hin recombinase bound to DNA: the origin of specificity in major and minor groove interactions. Science (1994) 1.83
Characterization of Borrelia burgdorferi isolates by restriction endonuclease analysis and DNA hybridization. J Clin Microbiol (1989) 1.83
Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservation. J Clin Invest (1996) 1.81
Recognition of streptococcal pharyngitis in adults. Arch Intern Med (1975) 1.81
Protective immunity is induced by a Borrelia burgdorferi mutant that lacks OspA and OspB. Infect Immun (1993) 1.79
Role of the IS50 R proteins in the promotion and control of Tn5 transposition. J Mol Biol (1984) 1.79
Neovascularization of synthetic membranes directed by membrane microarchitecture. J Biomed Mater Res (1995) 1.77
Lipids of the Spirochaetales: comparison of the lipids of several members of the genera Spirochaeta, Treponema, and Leptospira. J Bacteriol (1974) 1.77
Variable structures of Fis-DNA complexes determined by flanking DNA-protein contacts. J Mol Biol (1996) 1.74
Bloodstream invasion in early Lyme disease: results from a prospective, controlled, blinded study using the polymerase chain reaction. Am J Med (1995) 1.74
Copy number control of Tn5 transposition. Genetics (1984) 1.70
Flagellar hook and basal complex of Caulobacter crescentus. J Bacteriol (1979) 1.69
Characterization of leptospires according to fatty acid requirements. J Gen Microbiol (1969) 1.69
Pattern formation in the limbs of Drosophila: bric à brac is expressed in both a gradient and a wave-like pattern and is required for specification and proper segmentation of the tarsus. Development (1993) 1.68
Yeast HMG proteins NHP6A/B potentiate promoter-specific transcriptional activation in vivo and assembly of preinitiation complexes in vitro. Genes Dev (1996) 1.66
Colony formation and morphology in Borrelia burgdorferi. J Clin Microbiol (1987) 1.66
Cultivation of parasitic leptospires: effect of pyruvate. Appl Microbiol (1973) 1.65
Defects in hemostasis in P-selectin-deficient mice. Blood (1996) 1.64
Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding. EMBO J (1999) 1.63
Molecular detection of persistent Borrelia burgdorferi in the urine of patients with active Lyme disease. Infect Immun (1991) 1.63
DNA analysis of Borrelia burgdorferi NCH-1, the first northcentral U.S. human Lyme disease isolate. J Clin Microbiol (1992) 1.61
Borrelia lymphocytoma: a possible North American case. Wis Med J (1990) 1.61
Characterization of a circular plasmid from Borrelia burgdorferi, etiologic agent of Lyme disease. J Clin Microbiol (1988) 1.60
Amino acid biosynthesis in the spirochete Leptospira: evidence for a novel pathway of isoleucine biosynthesis. J Bacteriol (1974) 1.60
Sequence, regulation, and functions of fis in Salmonella typhimurium. J Bacteriol (1995) 1.59
Genetic analysis of Borrelia. Zentralbl Bakteriol Mikrobiol Hyg A (1986) 1.59
Treponeme outer cell envelope: solubilization and reaggregation. Infect Immun (1973) 1.58
Multiple effects of Fis on integration and the control of lysogeny in phage lambda. J Bacteriol (1991) 1.57
In vitro and in vivo induction of tumor necrosis factor alpha by Borrelia burgdorferi. Infect Immun (1992) 1.55
Seasonal prevalence of Borrelia burgdorferi in natural populations of white-footed mice, Peromyscus leucopus. J Clin Microbiol (1987) 1.55
Analysis and comparison of plasmid profiles of Borrelia burgdorferi sensu lato strains. J Clin Microbiol (1995) 1.54
Taxonomy of the Lyme disease spirochetes. Yale J Biol Med (1985) 1.53
Peromyscus leucopus and Microtus pennsylvanicus simultaneously infected with Borrelia burgdorferi and Babesia microti. J Clin Microbiol (1986) 1.52
Identification of genes negatively regulated by Fis: Fis and RpoS comodulate growth-phase-dependent gene expression in Escherichia coli. J Bacteriol (1995) 1.51
An isoform of kalirin, a brain-specific GDP/GTP exchange factor, is enriched in the postsynaptic density fraction. J Biol Chem (2000) 1.50
Electron microscopy of immune disruption of leptospires: action of complement and lysozyme. J Bacteriol (1968) 1.48
DNA looping by Saccharomyces cerevisiae high mobility group proteins NHP6A/B. Consequences for nucleoprotein complex assembly and chromatin condensation. J Biol Chem (1995) 1.47
Fis activates the RpoS-dependent stationary-phase expression of proP in Escherichia coli. J Bacteriol (1995) 1.46
Protein-free and low-protein media for the cultivation of Leptospira. Infect Immun (1978) 1.46
Lipid metabolism of Borrelia hermsi. Infect Immun (1978) 1.45
Inter- and intralaboratory comparison of Ehrlichia equi and human granulocytic ehrlichiosis (HGE) agent strains for serodiagnosis of HGE by the immunofluorescent-antibody test. J Clin Microbiol (1999) 1.45
The 83-kilodalton antigen of Borrelia burgdorferi which stimulates immunoglobulin M (IgM) and IgG responses in infected hosts is expressed by a chromosomal gene. J Clin Microbiol (1990) 1.44
Mechanism for specificity by HMG-1 in enhanceosome assembly. Mol Cell Biol (2000) 1.44
Phenotypic analysis of outer surface protein C (OspC) of Borrelia burgdorferi sensu lato by monoclonal antibodies: relationship to genospecies and OspA serotype. J Clin Microbiol (1995) 1.44
DNA binding and bending are necessary but not sufficient for Fis-dependent activation of rrnB P1. J Bacteriol (1993) 1.43