PubRank

M R Botchan

Author PubWeight™ 165.90‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The genome sequence of Drosophila melanogaster. Science 2000 74.32
2 High mutation frequency in DNA transfected into mammalian cells. Proc Natl Acad Sci U S A 1983 6.05
3 Characterization of the bovine papilloma virus plasmid maintenance sequences. Cell 1984 5.01
4 Targeting the E1 replication protein to the papillomavirus origin of replication by complex formation with the E2 transactivator. Science 1990 4.92
5 Genetic analysis of bovine papillomavirus type 1 trans-acting replication factors. J Virol 1985 4.74
6 Activation of BPV-1 replication in vitro by the transcription factor E2. Nature 1991 4.51
7 Association of the origin recognition complex with heterochromatin and HP1 in higher eukaryotes. Cell 1997 4.02
8 The acidic transcriptional activation domains of VP16 and p53 bind the cellular replication protein A and stimulate in vitro BPV-1 DNA replication. Cell 1993 3.68
9 Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcription. Cell 1991 3.46
10 Repression of bovine papilloma virus replication is mediated by a virally encoded trans-acting factor. Cell 1986 2.58
11 Segregation of viral plasmids depends on tethering to chromosomes and is regulated by phosphorylation. Proc Natl Acad Sci U S A 1998 2.50
12 Transient replication of bovine papilloma virus type 1 plasmids: cis and trans requirements. Proc Natl Acad Sci U S A 1986 2.49
13 The retinoblastoma gene product regulates Sp1-mediated transcription. Mol Cell Biol 1992 2.21
14 A Drosophila homolog of the yeast origin recognition complex. Science 1995 2.20
15 The cellular DNA polymerase alpha-primase is required for papillomavirus DNA replication and associates with the viral E1 helicase. Proc Natl Acad Sci U S A 1994 2.04
16 Acidic transcription factors alleviate nucleosome-mediated repression of DNA replication of bovine papillomavirus type 1. Proc Natl Acad Sci U S A 1994 1.98
17 An enhancer sequence from bovine papilloma virus DNA consists of two essential regions. Nucleic Acids Res 1984 1.98
18 Orc mutants arrest in metaphase with abnormally condensed chromosomes. Development 2001 1.84
19 Isolation and characterization of human DNA fragments with nucleotide sequence homologies with the simian virus 40 regulatory region. Mol Cell Biol 1982 1.82
20 Climate change and the integrity of science. Science 2010 1.80
21 A bovine papillomavirus type 1-encoded modulator function is dispensable for transient viral replication but is required for establishment of the stable plasmid state. J Virol 1986 1.74
22 DNA-binding domain of bovine papillomavirus type 1 E1 helicase: structural and functional aspects. J Virol 1993 1.73
23 Biochemical and electron microscopic image analysis of the hexameric E1 helicase. J Biol Chem 1999 1.66
24 The E2 trans-activator can act as a repressor by interfering with a cellular transcription factor. Genes Dev 1990 1.66
25 A promoter with an internal regulatory domain is part of the origin of replication in BPV-1. Science 1987 1.64
26 Separation of origin recognition complex functions by cross-species complementation. Science 1995 1.59
27 Genetic analysis of the activation domain of bovine papillomavirus protein E2: its role in transcription and replication. J Virol 1996 1.44
28 Distinct cytoplasmic and nuclear fractions of Drosophila heterochromatin protein 1: their phosphorylation levels and associations with origin recognition complex proteins. J Cell Biol 1998 1.43
29 Fragment spanning the SV40 replication origin is the only DNA sequence required in cis for viral excision. Science 1982 1.35
30 The E1 replication protein of bovine papillomavirus type 1 contains an extended nuclear localization signal that includes a p34cdc2 phosphorylation site. J Virol 1993 1.35
31 trans Activation of the simian virus 40 enhancer. Mol Cell Biol 1986 1.29
32 Crystal structure of the human papillomavirus type 18 E2 activation domain. Science 1999 1.28
33 p53 inhibits RNA polymerase III-directed transcription in a promoter-dependent manner. Mol Cell Biol 1996 1.26
34 Bovine satellite I DNA consists of repetitive units 1,400 base pairs in length. Nature 1974 1.21
35 cis-Acting components of human papillomavirus (HPV) DNA replication: linker substitution analysis of the HPV type 11 origin. J Virol 1995 1.21
36 A papillomavirus E2 phosphorylation mutant exhibits normal transient replication and transcription but is defective in transformation and plasmid retention. J Virol 1997 1.17
37 Origin recognition complex binding to a metazoan replication origin. Curr Biol 2001 1.17
38 Amplification of a bovine papillomavirus-simian virus 40 chimera. J Virol 1985 1.12
39 E1 recognition sequences in the bovine papillomavirus type 1 origin of DNA replication: interaction between half sites of the inverted repeats. J Virol 1995 1.11
40 Competition for DNA binding sites between the short and long forms of E2 dimers underlies repression in bovine papillomavirus type 1 DNA replication control. J Virol 1998 1.03
41 The E2 transactivator of bovine papillomavirus type 1 is expressed from multiple promoters. J Virol 1990 1.01
42 Another chromosomal assignment for a simian virus 40 integration site in human cells. Proc Natl Acad Sci U S A 1978 0.97
43 Simian virus 40-transformed human cells that express large T antigens defective for viral DNA replication. J Virol 1987 0.94
44 Site-specific DNA-binding proteins important for replication and transcription have multiple activities. Cold Spring Harb Symp Quant Biol 1993 0.94
45 Assembly of nucleosomes: do multiple assembly factors mean multiple mechanisms? Curr Opin Genet Dev 1994 0.91
46 DNA-mediated gene transfer efficiency is enhanced by ionizing and ultraviolet irradiation of rodent cells in vitro. I. Kinetics of enhancement. Radiat Res 1985 0.79
47 The E2 trans-activator can act as a repressor by interfering with a cellular transcription factor. Genes Dev 1990 0.76
48 A constitutive enhancer in the bovine papillomavirus upstream regulatory region shares genetic elements with the viral P1 promoter. J Virol 1992 0.76
49 The bovine papillomavirus E2 transactivator is stimulated by the E1 initiator through the E2 activation domain. Virology 2000 0.75
50 Competition between pentalysine and actinomycin D for binding to DNA. Biochem Biophys Res Commun 1972 0.75
51 Drosophila homolog of yeast ORC: correction. Science 1996 0.75
52 Drosophila Homolog of Yeast ORC: Correction. Science 1996 0.75