Published in Proc Natl Acad Sci U S A on June 01, 1986
Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae. Mol Cell Biol (1988) 7.10
Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames. EMBO J (1991) 6.00
A method for identifying the viral genes required for herpesvirus DNA replication. Proc Natl Acad Sci U S A (1986) 4.61
Identification of the origin of replication of bovine papillomavirus and characterization of the viral origin recognition factor E1. EMBO J (1991) 3.98
Trans-activation of an upstream early gene promoter of bovine papilloma virus-1 by a product of the viral E2 gene. EMBO J (1987) 3.65
Replication and segregation of plasmids containing cis-acting regulatory sites of silent mating-type genes in Saccharomyces cerevisiae are controlled by the SIR genes. Mol Cell Biol (1987) 2.68
The 68-kilodalton E1 protein of bovine papillomavirus is a DNA binding phosphoprotein which associates with the E2 transcriptional activator in vitro. J Virol (1991) 2.65
A bovine papillomavirus E1-related protein binds specifically to bovine papillomavirus DNA. J Virol (1991) 2.43
Bovine papillomavirus type 1 encodes two forms of a transcriptional repressor: structural and functional analysis of new viral cDNAs. J Virol (1989) 2.38
Inducible and constitutive enhancer domains in the noncoding region of human papillomavirus type 18. J Virol (1988) 2.19
Papillomavirus DNA replication. J Virol (1991) 1.92
Bovine papillomavirus mutant temperature sensitive for transformation, replication and transactivation. EMBO J (1988) 1.89
A bovine papillomavirus type 1-encoded modulator function is dispensable for transient viral replication but is required for establishment of the stable plasmid state. J Virol (1986) 1.74
Drosophila chorion gene amplification requires an upstream region regulating s18 transcription. Mol Cell Biol (1986) 1.66
Elements in the transcriptional regulatory region flanking herpes simplex virus type 1 oriS stimulate origin function. J Virol (1991) 1.66
Replication of bovine papillomavirus type 1 DNA initiates within an E2-responsive enhancer element. J Virol (1990) 1.64
The product of the bovine papillomavirus type 1 modulator gene (M) is a phosphoprotein. J Virol (1988) 1.60
Open reading frames E6 and E7 of bovine papillomavirus type 1 are both required for full transformation of mouse C127 cells. J Virol (1989) 1.52
DNA binding specificity of the bovine papillomavirus E1 protein is determined by sequences contained within an 18-base-pair inverted repeat element at the origin of replication. J Virol (1994) 1.51
Recognition mechanisms in the synthesis of animal virus DNA. Biochem J (1989) 1.49
Proteins encoded by the bovine papillomavirus E1 open reading frame: expression in heterologous systems and in virally transformed cells. J Virol (1990) 1.49
Site-specific DNA binding of nuclear factor I: effect of the spacer region. Nucleic Acids Res (1987) 1.41
Amplification of the X-linked Drosophila chorion gene cluster requires a region upstream from the s38 chorion gene. EMBO J (1987) 1.39
Transcriptional and replicational activation functions in the bovine papillomavirus type 1 E2 protein are encoded by different structural determinants. J Virol (1996) 1.33
Opposite replication polarity of the germ line c-myc gene in HeLa cells compared with that of two Burkitt lymphoma cell lines. Mol Cell Biol (1989) 1.26
A bovine papillomavirus constitutive enhancer is negatively regulated by the E2 repressor through competitive binding for a cellular factor. J Virol (1990) 1.25
Herpes simplex virus type 1 origin-specific binding protein: oriS-binding properties and effects of cellular proteins. J Virol (1991) 1.22
Replication of plasmid-derived human papillomavirus type 11 DNA in cultured keratinocytes. J Virol (1992) 1.21
Regulation of early gene expression from the bovine papillomavirus genome in transiently transfected C127 cells. J Virol (1991) 1.16
Characterization of human DNA sequences synthesized at the onset of S-phase. Nucleic Acids Res (1987) 1.07
Wheat dwarf virus vectors replicate and express foreign genes in cells of monocotyledonous plants. Plant Cell (1991) 1.01
Enhancer dependence of polyomavirus persistence in mouse kidneys. J Virol (1992) 1.01
Visualization of Drosophila melanogaster chorion genes undergoing amplification. Mol Cell Biol (1988) 1.01
Multiple cellular factors bind to cis-regulatory elements found inboard of the 5' palindrome of minute virus of mice. J Virol (1994) 1.00
Loss of bovine papillomavirus DNA replication control in growth-arrested transformed cells. J Virol (1989) 0.98
Gene targeting with a replication-defective adenovirus vector. J Virol (1995) 0.97
Analysis of gene expression using episomal mouse dihydrofolate reductase minigenes. Nucleic Acids Res (1988) 0.97
Cellular transcription factors enhance herpes simplex virus type 1 oriS-dependent DNA replication. J Virol (1998) 0.96
The biology and significance of human papillomavirus infections in the genital tract. Yale J Biol Med (1988) 0.93
The 23-kilodalton E1 phosphoprotein of bovine papillomavirus type 1 is nonessential for stable plasmid replication in murine C127 cells. J Virol (1993) 0.92
Inactivation of p53 rescues the maintenance of high risk HPV DNA genomes deficient in expression of E6. PLoS Pathog (2013) 0.90
Selective enhancement of bovine papillomavirus type 1 DNA replication in Xenopus laevis eggs by the E6 gene product. Mol Cell Biol (1989) 0.88
The bovine papillomavirus genome and its uses as a eukaryotic vector. Biochem J (1987) 0.80
Regulation of bovine papillomavirus type 1 gene expression by RNA processing. Front Biosci (Landmark Ed) (2009) 0.80
Two cellular single-strand-specific DNA-binding proteins interact with two regions of the bovine papillomavirus type 1 genome, including the origin of DNA replication. J Virol (1992) 0.77
A constitutive enhancer in the bovine papillomavirus upstream regulatory region shares genetic elements with the viral P1 promoter. J Virol (1992) 0.76
Distinct roles of two binding sites for the bovine papillomavirus (BPV) E2 transactivator on BPV DNA replication. J Virol (1998) 0.75
Episomal maintenance of a bovine papilloma virus vector in transgenic mice. Mol Cell Biol (1987) 0.75
Viral and cellular oncogenes in papillomavirus-associated cancers. Br J Cancer Suppl (1988) 0.75
Selective extraction of polyoma DNA from infected mouse cell cultures. J Mol Biol (1967) 106.91
Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences. Nature (1981) 13.89
Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences. Proc Natl Acad Sci U S A (1981) 9.27
New procedure for DNA transfection with polycation and dimethyl sulfoxide. Mol Cell Biol (1984) 8.63
Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product. Cell (1985) 7.56
The primary structure and genetic organization of the bovine papillomavirus type 1 genome. Nature (1982) 7.24
A quantitative in vitro focus assay for bovine papilloma virus. Virology (1980) 7.14
Isolation of mutants of an animal virus in bacteria. Science (1980) 6.81
Bovine papillomavirus contains multiple transforming genes. Proc Natl Acad Sci U S A (1985) 6.73
In vitro tumorigenic transformation by a defined sub-genomic fragment of bovine papilloma virus DNA. Nature (1980) 6.67
A putative origin of replication of plasmids derived from Epstein-Barr virus is composed of two cis-acting components. Mol Cell Biol (1985) 6.44
In vitro mutagenesis of a circular DNA molecule by using synthetic restriction sites. Proc Natl Acad Sci U S A (1978) 5.32
Transformation and replication in mouse cells of a bovine papillomavirus--pML2 plasmid vector that can be rescued in bacteria. Proc Natl Acad Sci U S A (1982) 5.22
Characterization of the bovine papilloma virus plasmid maintenance sequences. Cell (1984) 5.01
Territorial limits and functional anatomy of the simian virus 40 replication origin. Proc Natl Acad Sci U S A (1982) 4.77
Localization and analysis of bovine papillomavirus type 1 transforming functions. J Virol (1984) 4.77
Genetic analysis of bovine papillomavirus type 1 trans-acting replication factors. J Virol (1985) 4.74
Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells. Proc Natl Acad Sci U S A (1982) 4.69
Bovine papilloma virus contains an activator of gene expression at the distal end of the early transcription unit. Mol Cell Biol (1983) 4.56
Polyoma virus DNA replication requires an enhancer. Nature (1984) 4.32
Polyomavirus enhancer contains multiple redundant sequence elements that activate both DNA replication and gene expression. Mol Cell Biol (1985) 3.91
Messenger RNAs from the transforming region of bovine papilloma virus type I. J Mol Biol (1985) 3.73
Apparent lack of integration of bovine papillomavirus DNA in virus-induced equine and bovine tumor cells and virus-transformed mouse cells. Virology (1981) 2.44
Origin of replication in episomal bovine papilloma virus type 1 DNA isolated from transformed cells. EMBO J (1984) 2.26
Nonsense mutation in open reading frame E2 of bovine papillomavirus DNA. J Virol (1986) 2.22
Polyoma mutants that productively infect F9 embryonal carcinoma cells do not rescue wild-type polyoma in F9 cells. Proc Natl Acad Sci U S A (1982) 2.09
An enhancer sequence from bovine papilloma virus DNA consists of two essential regions. Nucleic Acids Res (1984) 1.98
Complementation of a bovine papilloma virus low-copy-number mutant: evidence for a temporal requirement of the complementing gene. Mol Cell Biol (1986) 1.96
Sequences of bovine papillomavirus type 1 DNA--functional and evolutionary implications. Nucleic Acids Res (1983) 1.68
Initiation of enzymatic replication at the origin of the Escherichia coli chromosome: contributions of RNA polymerase and primase. Proc Natl Acad Sci U S A (1985) 1.59
Isolation of episomal bovine papillomavirus chromatin and identification of a DNase I-hypersensitive region. J Virol (1983) 1.24
The genome sequence of Drosophila melanogaster. Science (2000) 74.32
Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences. Nature (1981) 13.89
High mutation frequency in DNA transfected into mammalian cells. Proc Natl Acad Sci U S A (1983) 6.05
Characterization of the bovine papilloma virus plasmid maintenance sequences. Cell (1984) 5.01
Targeting the E1 replication protein to the papillomavirus origin of replication by complex formation with the E2 transactivator. Science (1990) 4.92
Genetic analysis of bovine papillomavirus type 1 trans-acting replication factors. J Virol (1985) 4.74
Bovine papilloma virus contains an activator of gene expression at the distal end of the early transcription unit. Mol Cell Biol (1983) 4.56
Activation of BPV-1 replication in vitro by the transcription factor E2. Nature (1991) 4.51
Association of the origin recognition complex with heterochromatin and HP1 in higher eukaryotes. Cell (1997) 4.02
The acidic transcriptional activation domains of VP16 and p53 bind the cellular replication protein A and stimulate in vitro BPV-1 DNA replication. Cell (1993) 3.68
Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcription. Cell (1991) 3.46
Bovine papilloma virus (BPV)-encoded E1 protein contains multiple activities required for BPV DNA replication. Proc Natl Acad Sci U S A (1993) 2.95
Bovine papilloma virus (BPV)-encoded E2 protein enhances binding of E1 protein to the BPV replication origin. Proc Natl Acad Sci U S A (1993) 2.74
Repression of bovine papilloma virus replication is mediated by a virally encoded trans-acting factor. Cell (1986) 2.58
Segregation of viral plasmids depends on tethering to chromosomes and is regulated by phosphorylation. Proc Natl Acad Sci U S A (1998) 2.50
Effect of repetitive imaging on topographic measurements of the optic nerve head. Arch Ophthalmol (1993) 2.40
Expression of two proteins from overlapping and oppositely oriented genes on transposable DNA insertion element IS5. Nature (1982) 2.39
The retinoblastoma gene product regulates Sp1-mediated transcription. Mol Cell Biol (1992) 2.21
A Drosophila homolog of the yeast origin recognition complex. Science (1995) 2.20
Functional analysis of the replicator structure of lambdoid bacteriophage DNAs. Cold Spring Harb Symp Quant Biol (1979) 2.18
The cellular DNA polymerase alpha-primase is required for papillomavirus DNA replication and associates with the viral E1 helicase. Proc Natl Acad Sci U S A (1994) 2.04
Acidic transcription factors alleviate nucleosome-mediated repression of DNA replication of bovine papillomavirus type 1. Proc Natl Acad Sci U S A (1994) 1.98
An enhancer sequence from bovine papilloma virus DNA consists of two essential regions. Nucleic Acids Res (1984) 1.98
Orc mutants arrest in metaphase with abnormally condensed chromosomes. Development (2001) 1.84
Isolation and characterization of human DNA fragments with nucleotide sequence homologies with the simian virus 40 regulatory region. Mol Cell Biol (1982) 1.82
Climate change and the integrity of science. Science (2010) 1.80
A bovine papillomavirus type 1-encoded modulator function is dispensable for transient viral replication but is required for establishment of the stable plasmid state. J Virol (1986) 1.74
DNA-binding domain of bovine papillomavirus type 1 E1 helicase: structural and functional aspects. J Virol (1993) 1.73
The E2 trans-activator can act as a repressor by interfering with a cellular transcription factor. Genes Dev (1990) 1.66
Biochemical and electron microscopic image analysis of the hexameric E1 helicase. J Biol Chem (1999) 1.66
Induction of structural changes in the bovine papillomavirus type 1 origin of replication by the viral E1 and E2 proteins. Proc Natl Acad Sci U S A (1994) 1.65
A promoter with an internal regulatory domain is part of the origin of replication in BPV-1. Science (1987) 1.64
Separation of origin recognition complex functions by cross-species complementation. Science (1995) 1.59
Genetic analysis of the activation domain of bovine papillomavirus protein E2: its role in transcription and replication. J Virol (1996) 1.44
Distinct cytoplasmic and nuclear fractions of Drosophila heterochromatin protein 1: their phosphorylation levels and associations with origin recognition complex proteins. J Cell Biol (1998) 1.43
Fragment spanning the SV40 replication origin is the only DNA sequence required in cis for viral excision. Science (1982) 1.35
The E1 replication protein of bovine papillomavirus type 1 contains an extended nuclear localization signal that includes a p34cdc2 phosphorylation site. J Virol (1993) 1.35
trans Activation of the simian virus 40 enhancer. Mol Cell Biol (1986) 1.29
Crystal structure of the human papillomavirus type 18 E2 activation domain. Science (1999) 1.28
p53 inhibits RNA polymerase III-directed transcription in a promoter-dependent manner. Mol Cell Biol (1996) 1.26
The bovine papillomavirus replicon. Ciba Found Symp (1986) 1.22
Bovine satellite I DNA consists of repetitive units 1,400 base pairs in length. Nature (1974) 1.21
cis-Acting components of human papillomavirus (HPV) DNA replication: linker substitution analysis of the HPV type 11 origin. J Virol (1995) 1.21
A papillomavirus E2 phosphorylation mutant exhibits normal transient replication and transcription but is defective in transformation and plasmid retention. J Virol (1997) 1.17
Origin recognition complex binding to a metazoan replication origin. Curr Biol (2001) 1.17
Amplification of a bovine papillomavirus-simian virus 40 chimera. J Virol (1985) 1.12
E1 recognition sequences in the bovine papillomavirus type 1 origin of DNA replication: interaction between half sites of the inverted repeats. J Virol (1995) 1.11
Inceptor and origin of DNA replication in lambdoid coliphages. I. The lambda DNA minimal replication system. Gene (1979) 1.11
Short-wavelength color visual fields in glaucoma suspects at risk. Am J Ophthalmol (1993) 1.08
Two DNA-bound E2 dimers are required for strong transcriptional activation and for cooperation with cellular factors in most cells. New Biol (1991) 1.06
Persistent hepatic expression of human apo A-I after transfer with a helper-virus independent adenoviral vector. Gene Ther (2002) 1.04
Gene therapy with recombinant adenovirus vectors: evaluation of the host immune response. Immunol Lett (1997) 1.04
Competition for DNA binding sites between the short and long forms of E2 dimers underlies repression in bovine papillomavirus type 1 DNA replication control. J Virol (1998) 1.03
The E2 transactivator of bovine papillomavirus type 1 is expressed from multiple promoters. J Virol (1990) 1.01
Modulation of the inflammatory properties and hepatotoxicity of recombinant adenovirus vectors by the viral E4 gene products. Hum Gene Ther (2000) 1.00
Short-term effects of levobunolol on ocular pulsatile flow. Am J Ophthalmol (1992) 0.98
Another chromosomal assignment for a simian virus 40 integration site in human cells. Proc Natl Acad Sci U S A (1978) 0.97
Clinical dose-regimen studies with latanoprost, a new ocular hypotensive PGF2 alpha analogue. Surv Ophthalmol (1997) 0.96
Simian virus 40-transformed human cells that express large T antigens defective for viral DNA replication. J Virol (1987) 0.94
Site-specific DNA-binding proteins important for replication and transcription have multiple activities. Cold Spring Harb Symp Quant Biol (1993) 0.94
Assembly of nucleosomes: do multiple assembly factors mean multiple mechanisms? Curr Opin Genet Dev (1994) 0.91
A comparison of generalization functions and frame of reference effects in different training paradigms. Percept Psychophys (1992) 0.91
Age-related changes in the human lens: a comparison of Scheimpflug photography and lens density index. J Cataract Refract Surg (1994) 0.87
Augmented trabeculectomy in paediatric glaucoma. Br J Ophthalmol (2005) 0.85
Pupillary block following posterior chamber intraocular lens implantation in adults. Br J Ophthalmol (2003) 0.84
Radioisotopic imaging allows optimization of adenovirus lung deposition for cystic fibrosis gene therapy. Hum Gene Ther (2001) 0.83
Reproducibility of quantitative anterior chamber angle measurements with scheimpflug video imaging. J Glaucoma (1992) 0.82
Targeting of adenovirus vectors carrying a tumor cell-specific peptide: in vitro and in vivo studies. Cancer Gene Ther (2007) 0.80
Mitomycin C and 5-fluorouracil antimetabolite therapy for pediatric glaucoma filtration surgery. Ophthalmic Surg Lasers (2000) 0.80
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Late visual field changes following cryotherapy for retinopathy of prematurity stage 3. Br J Ophthalmol (1995) 0.78
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Effects of first generation E1E3-deleted and second generation E1E3E4-deleted/modified adenovirus vectors on human endothelial cell death. Endothelium (2001) 0.77
A constitutive enhancer in the bovine papillomavirus upstream regulatory region shares genetic elements with the viral P1 promoter. J Virol (1992) 0.76
The E2 trans-activator can act as a repressor by interfering with a cellular transcription factor. Genes Dev (1990) 0.76
The effect of topical beta-adrenoceptor blocking agents on pulsatile ocular blood flow. Eye (Lond) (1995) 0.76
Inceptor and origin of DNA replication in lambdoid coliphages. II. The lambda DNA maximal replication system. Gene (1979) 0.76
The use of fibrin adhesive in trabeculectomy: a pilot study. Br J Ophthalmol (2006) 0.75
Gene transfer into canine myoblasts. Cytotechnology (1999) 0.75
Intravitreal gas injection for hypotony after cataract surgery. J Cataract Refract Surg (1998) 0.75
Anterior chamber angle configuration before and after iridotomy measured by scheimpflug video imaging. J Glaucoma (1994) 0.75
Implantation growth of an iris melanocytic lesion simulating a ciliary body melanoma. Ophthalmic Surg (1987) 0.75
The prevalence of retinal detachment in aphakic high myopic patients. Ophthalmic Surg (1987) 0.75
[Visual disturbances in mitral valve prolapse]. Harefuah (1987) 0.75
Unusual posterior retinal holes associated with high myopia in XYY syndrome. Ann Ophthalmol (1990) 0.75
Threshold sensitivity tests in various ocular diseases. Ann Ophthalmol (1989) 0.75
Detection of replicational inceptor signals in IS5. Cold Spring Harb Symp Quant Biol (1981) 0.75
Drosophila homolog of yeast ORC: correction. Science (1996) 0.75
[Lowering intraocular pressure in glaucoma--by how much?]. Harefuah (1999) 0.75
A microtest plate assay of functional excitatory amino acid receptors. J Neurosci Methods (1989) 0.75
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The bovine papillomavirus E2 transactivator is stimulated by the E1 initiator through the E2 activation domain. Virology (2000) 0.75
Ultrasonographic findings of the optic disc in congenital glaucoma. Ophthalmic Surg Lasers (1996) 0.75