Published in Am J Respir Crit Care Med on December 01, 1997
Idiopathic pulmonary fibrosis. Orphanet J Rare Dis (2008) 2.34
Oxidative stress in pulmonary fibrosis: a possible role for redox modulatory therapy. Am J Respir Crit Care Med (2005) 2.29
Dyskeratosis congenita, stem cells and telomeres. Biochim Biophys Acta (2009) 1.62
Oxidative stress and glutathione in TGF-beta-mediated fibrogenesis. Free Radic Biol Med (2009) 1.61
The role of inflammation in the pathogenesis of idiopathic pulmonary fibrosis. Antioxid Redox Signal (2008) 1.60
Lung function in idiopathic pulmonary fibrosis--extended analyses of the IFIGENIA trial. Respir Res (2009) 1.34
Oxidative stress, plasminogen activator inhibitor 1, and lung fibrosis. Antioxid Redox Signal (2008) 1.31
Glutathione suppresses TGF-beta-induced PAI-1 expression by inhibiting p38 and JNK MAPK and the binding of AP-1, SP-1, and Smad to the PAI-1 promoter. Am J Physiol Lung Cell Mol Physiol (2007) 1.22
Idiopathic pulmonary fibrosis: current understanding of the pathogenesis and the status of treatment. CMAJ (2004) 1.21
A review of current and novel therapies for idiopathic pulmonary fibrosis. J Thorac Dis (2013) 1.18
In vivo antioxidant treatment protects against bleomycin-induced lung damage in rats. Br J Pharmacol (2003) 1.07
Antioxidants as potential therapeutics for lung fibrosis. Antioxid Redox Signal (2008) 1.02
Epithelial-mesenchymal interactions in pulmonary fibrosis. Semin Respir Crit Care Med (2006) 0.99
Differential anti-inflammatory and anti-oxidative effects of dexamethasone and N-acetylcysteine in endotoxin-induced lung inflammation. Clin Exp Immunol (2000) 0.98
Current and novel drug therapies for idiopathic pulmonary fibrosis. Drug Des Devel Ther (2012) 0.93
Glutathione supplementation attenuates lipopolysaccharide-induced mitochondrial dysfunction and apoptosis in a mouse model of acute lung injury. Front Physiol (2012) 0.91
Idiopathic pulmonary fibrosis : new concepts in pathogenesis and implications for drug therapy. Treat Respir Med (2006) 0.90
P-selectin upregulation in bleomycin induced lung injury in rats: effect of N-acetyl-L-cysteine. Thorax (2002) 0.89
Targeting maladaptive glutathione responses in lung disease. Biochem Pharmacol (2010) 0.89
The treatment of idiopathic pulmonary fibrosis. F1000Prime Rep (2014) 0.86
N-acetylcysteine infusion reduces the resistance index of renal artery in the early stage of systemic sclerosis. Acta Pharmacol Sin (2009) 0.85
Idiopathic interstitial pneumonias: progress in classification, diagnosis, pathogenesis and management. Trans Am Clin Climatol Assoc (2004) 0.84
Reciprocal regulation of TGF-β and reactive oxygen species: A perverse cycle for fibrosis. Redox Biol (2015) 0.83
The treatment with N-acetylcysteine of Raynaud's phenomenon and ischemic ulcers therapy in sclerodermic patients: a prospective observational study of 50 patients. Clin Rheumatol (2009) 0.83
Idiopathic pulmonary fibrosis: early detection and referral. Respir Med (2014) 0.82
TGF-β: Titan of Lung Fibrogenesis. Curr Enzym Inhib (2010) 0.81
Double-Blind Randomized Trial of Pirfenidone in Chinese Idiopathic Pulmonary Fibrosis Patients. Medicine (Baltimore) (2015) 0.81
Pharmacological treatment of idiopathic pulmonary fibrosis - preclinical and clinical studies of pirfenidone, nintedanib, and N-acetylcysteine. Eur Clin Respir J (2015) 0.80
N-acetylcysteine negatively regulates Notch3 and its malignant signaling. Oncotarget (2016) 0.80
Self-eating: friend or foe? The emerging role of autophagy in idiopathic pulmonary fibrosis. Biomed Res Int (2013) 0.78
Antidiabetic Effects of Yam (Dioscorea batatas) and Its Active Constituent, Allantoin, in a Rat Model of Streptozotocin-Induced Diabetes. Nutrients (2015) 0.77
Exhaled 8-isoprostane as a prognostic marker in sarcoidosis. A short term follow-up. BMC Pulm Med (2010) 0.77
Nigella sativa seed extract attenuates the fatigue induced by exhaustive swimming in rats. Biomed Rep (2017) 0.75
Exhaled 8-isoprostane in sarcoidosis: relation to superoxide anion production by bronchoalveolar lavage cells. Inflamm Res (2010) 0.75
[Pulmonary fibrosis. Classification, diagnosis, therapy]. Internist (Berl) (2003) 0.75
Performance and Side Effects of Supplementation with N-Acetylcysteine: A Systematic Review and Meta-Analysis. Sports Med (2017) 0.75
Defective smooth muscle regulation in cGMP kinase I-deficient mice. EMBO J (1998) 2.96
Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction. Cell Tissue Res (2001) 2.45
Therapeutic efficacy of sulfasalazine and its metabolites in patients with ulcerative colitis and Crohn's disease. N Engl J Med (1980) 2.39
Mast cells control neutrophil recruitment during T cell-mediated delayed-type hypersensitivity reactions through tumor necrosis factor and macrophage inflammatory protein 2. J Exp Med (2000) 2.00
Elevated levels of interleukin-8 and transforming growth factor-beta in bronchoalveolar lavage fluid from patients with bronchiolitis obliterans syndrome: proinflammatory role of bronchial epithelial cells. Munich Lung Transplant Group. Transplantation (2000) 1.84
Symptom variability in patients with severe COPD: a pan-European cross-sectional study. Eur Respir J (2010) 1.78
Platelet-endothelial cell interactions during ischemia/reperfusion: the role of P-selectin. Blood (1998) 1.65
COPD: early diagnosis and treatment to slow disease progression. Int J Clin Pract (2014) 1.63
[Guidelines for diagnosis and treatment of asthma patients]. Pneumologie (2006) 1.59
Fibrinogen deposition at the postischemic vessel wall promotes platelet adhesion during ischemia-reperfusion in vivo. Blood (1999) 1.51
[Rare diseases in pulmonary medicine and its challenges]. Pneumologie (2012) 1.39
[beta(2)-Sympathomimetics: risks for asthma therapy? Lessons from the SMART1 Study. A statement from the German Respiratory Tract League]. Dtsch Med Wochenschr (2007) 1.39
[Established combinations of inhaled corticoids and long-acting beta 2-symphathomimetics for long-term therapy of bronchial asthma. Position of an expert panel study]. Pneumologie (1999) 1.38
[Chronic obstructive pulmonary disease (COPD)]. Dtsch Med Wochenschr (2012) 1.38
Neuroprotective effects and intracellular signaling pathways of erythropoietin in a rat model of multiple sclerosis. Cell Death Differ (2004) 1.33
Liver-derived cytotoxic T cells in hepatitis A virus infection. J Infect Dis (1989) 1.29
Increased adhesion and aggregation of platelets lacking cyclic guanosine 3',5'-monophosphate kinase I. J Exp Med (1999) 1.24
Cell-mediated cytotoxicity in hepatitis A virus infection. Hepatology (1987) 1.23
Bronchoalveolar lavage for evaluation and management of scleroderma disease of the lung. Am J Respir Crit Care Med (1996) 1.22
Electrophoretic characterization of wheat grain allergens from different cultivars involved in bakers' asthma. Electrophoresis (1993) 1.16
Pulmonary function and health-related quality of life in a sample of long-term survivors of the acute respiratory distress syndrome. Intensive Care Med (2000) 1.16
Suppression of pulmonary innate host defence in smokers. Thorax (2008) 1.12
Kinetics of white blood cell staining by intravascular administration of rhodamine 6G. Int J Microcirc Clin Exp (1996) 1.12
Lymphangioleiomyomatosis: recurrence after single lung transplantation. Hum Pathol (1997) 1.09
Clonal analysis of infiltrating T lymphocytes in liver tissue in viral hepatitis A. Immunology (1990) 1.08
Simplified high-performance liquid chromatographic method for 5-aminosalicylic acid in plasma and urine. J Chromatogr (1981) 1.07
Criteria for development of a database for safety evaluation of fragrance ingredients. Regul Toxicol Pharmacol (2000) 1.05
Molecular basis of the liver and lung disease associated with the alpha 1-antitrypsin deficiency allele Mmalton. J Biol Chem (1989) 1.05
Automatic CPAP titration with different self-setting devices in patients with obstructive sleep apnoea. Eur Respir J (2004) 1.04
TNF-alpha-, TNF-beta-, IL-6-, and IL-10-promoter polymorphisms in patients with chronic obstructive pulmonary disease. Tissue Antigens (2005) 1.03
Recombinant secretory leukoprotease inhibitor augments glutathione levels in lung epithelial lining fluid. J Appl Physiol (1985) (1993) 1.02
Determination of the centre of resistance in an upper human canine and idealized tooth model. Eur J Orthod (1999) 1.01
Exacerbations of COPD: quantifying the patient's perspective using discrete choice modelling. Eur Respir J (2005) 1.00
Quantitative analysis of small intestinal microcirculation in the mouse. Res Exp Med (Berl) (1998) 1.00
Augmentation of glutathione in the fluid lining the epithelium of the lower respiratory tract by directly administering glutathione aerosol. Proc Natl Acad Sci U S A (1990) 0.99
Humidifier lung and humidifier fever. Lung (1988) 0.99
Sympathetic activity is reduced by nCPAP in hypertensive obstructive sleep apnoea patients. Eur Respir J (2004) 0.98
Construction and testing of a computer-based intraoral laser scanner for determining tooth positions. Med Eng Phys (2000) 0.98
Use of dreams in therapy: a survey of clinicians in private practice. Psychol Rep (1995) 0.97
Risk factors for emphysema. Cigarette smoking is associated with a reduction in the association rate constant of lung alpha 1-antitrypsin for neutrophil elastase. J Clin Invest (1991) 0.97
ESPEN Guidelines on Enteral Nutrition: Cardiology and pulmonology. Clin Nutr (2006) 0.96
Species differences in NO formation by rat and hamster alveolar macrophages in vitro. Am J Respir Cell Mol Biol (1997) 0.96
Oxidant-protease interaction in the lung. Prospects for antioxidant therapy. Chest (1996) 0.96
Effect of caffeine on oxygen consumption and metabolic rate in very low birth weight infants with idiopathic apnea. Pediatrics (2001) 0.96
Characterization and quantification of alveolar monocyte-like cells in human chronic inflammatory lung disease. Eur Respir J (1996) 0.95
Plasminogen activation in healing human wounds. Am J Pathol (1994) 0.95
Maize glutathione-dependent formaldehyde dehydrogenase: protein sequence and catalytic properties. Planta (1999) 0.94
Phenotypic and functional differences between rat alveolar, pleural, and peritoneal macrophages. Exp Lung Res (2001) 0.94
Late pulmonary impairment following allogeneic bone marrow transplantation. Eur J Med Res (1996) 0.93
Intracellular glutathione and bronchoalveolar cells in fibrosing alveolitis: effects of N-acetylcysteine. Eur Respir J (2002) 0.93
Occupational asthma in hairdressers: results of inhalation tests with bleaching powder. Int Arch Occup Environ Health (1997) 0.92
Peripheral airspace dimensions in patients with COPD. Chest (1995) 0.92
Molecular basis of alpha 1-antitrypsin deficiency and emphysema associated with the alpha 1-antitrypsin Mmineral springs allele. Mol Cell Biol (1990) 0.92
Purification and molecular characterization of two inhibitors of yeast proteinase B. J Biol Chem (1979) 0.92
A prospective polysomnographic study on the evolution of complex sleep apnoea. Eur Respir J (2011) 0.92
[Systemic manifestations and comorbidities in patients with chronic obstructive pulmonary disease (COPD) and their effect on clinical state and course of the disease--an overview of the cohort study COSYCONET]. Dtsch Med Wochenschr (2010) 0.91
Increased sputum IL-8 and IL-5 in asymptomatic nonspecific airway hyperresponsiveness. Lung (2001) 0.91
Increased oxidation of extracellular glutathione by bronchoalveolar inflammatory cells in diffuse fibrosing alveolitis. Eur Respir J (1995) 0.91
Expression of inducible nitric oxide synthase and formation of nitric oxide by alveolar macrophages: an interspecies comparison. Environ Health Perspect (1997) 0.91
[Health effects of particulate matter exposure: current scientific knowledge]. Pneumologie (2009) 0.91
Airflow limitation, lung volumes and systemic inflammation in a general population. Eur Respir J (2011) 0.91
Differential responses of rat alveolar and peritoneal macrophages to man-made vitreous fibers in vitro. Environ Res (2001) 0.90
Reversal of established delayed type hypersensitivity reactions following therapy with IL-4 or antigen-specific Th2 cells. Eur J Immunol (2001) 0.90
Rhesus monkey (Macaca mulatta) mucosal antimicrobial peptides are close homologues of human molecules. Clin Diagn Lab Immunol (2001) 0.89
Functional significance of cardiac reinnervation in heart transplant recipients. J Heart Lung Transplant (1999) 0.89
The role of neutrophils in the pathogenesis of obliterative bronchiolitis after lung transplantation. Transpl Infect Dis (2001) 0.89
Inhaled glutathione decreases PGE2 and increases lymphocytes in cystic fibrosis lungs. Free Radic Biol Med (2005) 0.89
Transforming growth factor-beta1 is a potent inhibitor of secretory leukoprotease inhibitor expression in a bronchial epithelial cell line. Munich Lung Transplant Group. Eur Respir J (2000) 0.89
Specific measurement of 5-aminosalicylic acid and its acetylated metabolite in human bile. Br J Clin Pharmacol (1983) 0.88
Fibroblast chemotactic response elicited by native bronchoalveolar lavage fluid from patients with fibrosing alveolitis. Thorax (1993) 0.88
Differential function of nitric oxide in murine antigen-induced arthritis. Rheumatology (Oxford) (2002) 0.87
Bacterial expression of G-protein-coupled receptors: prediction of expression levels from sequence. Receptors Channels (2000) 0.87
Mechanisms of cytokine cascade activation in patients with sepsis: normal cytokine transcription despite reduced CD14 receptor expression. Surgery (1993) 0.87
Bronchial epithelial cell B7-1 and B7-2 mRNA expression after lung transplantation: a role in allograft rejection? Eur Respir J (2002) 0.87
Analysis of sleep fragmentation and sleep structure in patients with sleep apnea and normal volunteers. Conf Proc IEEE Eng Med Biol Soc (2005) 0.86
Bronchiolitis obliterans syndrome after (heart-)lung transplantation. Impaired antiprotease defense and increased oxidant activity. Am J Respir Crit Care Med (1999) 0.86
Bronchoalveolar lavage fluid proteins in human lung disease: analysis by two-dimensional electrophoresis. Electrophoresis (1993) 0.86
Hyperoxia upregulates the NO pathway in alveolar macrophages in vitro: role of AP-1 and NF-kappaB. Am J Physiol Lung Cell Mol Physiol (2001) 0.86
Quantum dots modulate leukocyte adhesion and transmigration depending on their surface modification. Nano Lett (2010) 0.86
Imaging of leukocytes within the rat brain cortex in vivo. Microvasc Res (1991) 0.86
Budesonide/formoterol maintenance and reliever therapy: a new treatment approach for adult patients with asthma. Curr Med Res Opin (2007) 0.85
Neutrophil proteinases and rhDNase therapy in cystic fibrosis. Eur Respir J (1996) 0.85
Disposition of ibuprofen in patients with liver cirrhosis. Stereochemical considerations. Clin Pharmacokinet (1993) 0.85
Refolding of G-protein-coupled receptors from inclusion bodies produced in Escherichia coli. Biochem Soc Trans (1999) 0.85
In vitro effects of oxidized low density lipoprotein on CD11b/CD18 and L-selectin presentation on neutrophils and monocytes with relevance for the in vivo situation. Am J Pathol (1995) 0.85
Exacerbation of antigen-induced arthritis in inducible nitric oxide synthase-deficient mice. Arthritis Rheum (2001) 0.85
A novel model for the study of synovial microcirculation in the mouse knee joint in vivo. Res Exp Med (Berl) (1998) 0.84
Platelet adhesion and fibrinogen deposition in murine microvessels upon inhalation of nanosized carbon particles. J Thromb Haemost (2010) 0.84
Attenuation of postischemic microvascular disturbances in striated muscle by hyperosmolar saline dextran. Am J Physiol (1992) 0.84
Renal function was not impaired by treatment with 5-aminosalicylic acid in rats and man. Naunyn Schmiedebergs Arch Pharmacol (1984) 0.84
Evidence for oxidative stress in bronchiolitis obliterans syndrome after lung and heart-lung transplantation. The Munich Lung Transplant Group. Transplantation (2000) 0.83
Comparison of the phagocytic response of rat and hamster alveolar macrophages to man-made vitreous fibers in vitro. Hum Exp Toxicol (2000) 0.83