Increased adhesion and aggregation of platelets lacking cyclic guanosine 3',5'-monophosphate kinase I.

PubWeight™: 1.24‹?› | Rank: Top 10%

🔗 View Article (PMC 2193024)

Published in J Exp Med on April 19, 1999

Authors

S Massberg1, M Sausbier, P Klatt, M Bauer, A Pfeifer, W Siess, R Fässler, P Ruth, F Krombach, F Hofmann

Author Affiliations

1: Institut für Chirurgische Forschung der Ludwig-Maximilians-Universität München, 81377 München, Germany.

Articles citing this

Platelets in inflammation and atherogenesis. J Clin Invest (2005) 4.10

Defective thrombus formation in mice lacking coagulation factor XII. J Exp Med (2005) 3.59

cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action. Pharmacol Rev (2010) 3.27

A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation. J Exp Med (2002) 2.75

Fatal gastrointestinal obstruction and hypertension in mice lacking nitric oxide-sensitive guanylyl cyclase. Proc Natl Acad Sci U S A (2007) 2.24

Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling. Blood (2007) 1.73

Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway. J Immunol (2009) 1.70

Oxidized LDL activates blood platelets through CD36/NOX2-mediated inhibition of the cGMP/protein kinase G signaling cascade. Blood (2015) 1.48

Stimulation of guanylyl cyclase-D by bicarbonate. Biochemistry (2009) 1.09

The multiple actions of NO. Pflugers Arch (2009) 1.05

Insulin induces the release of vasodilator compounds from platelets by a nitric oxide-G kinase-VAMP-3-dependent pathway. J Exp Med (2004) 0.97

Platelet-derived HMGB1 is a critical mediator of thrombosis. J Clin Invest (2015) 0.91

Activation of haem-oxidized soluble guanylyl cyclase with BAY 60-2770 in human platelets lead to overstimulation of the cyclic GMP signaling pathway. PLoS One (2012) 0.85

cGMP-dependent protein kinase I is crucial for angiogenesis and postnatal vasculogenesis. PLoS One (2009) 0.84

Nanomedicine and Cardiovascular Disease. Curr Cardiovasc Imaging Rep (2010) 0.84

Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis. Proc Natl Acad Sci U S A (2014) 0.84

Phosphodiesterases maintain signaling fidelity via compartmentalization of cyclic nucleotides. Physiology (Bethesda) (2014) 0.82

Nitric oxide production pathways in erythrocytes and plasma. Biorheology (2009) 0.81

Platelet signaling: a complex interplay between inhibitory and activatory networks. J Thromb Haemost (2016) 0.81

Mechanisms underlying nitrate-induced endothelial dysfunction: insight from experimental and clinical studies. Heart Fail Rev (2002) 0.81

Homologous desensitization of signalling by the alpha (alpha) isoform of the human thromboxane A2 receptor: a specific role for nitric oxide signalling. Biochim Biophys Acta (2007) 0.81

Altered nitric oxide/cGMP platelet signaling pathway in platelets from patients with acute coronary syndromes. Clin Res Cardiol (2010) 0.80

The C. elegans cGMP-dependent protein kinase EGL-4 regulates nociceptive behavioral sensitivity. PLoS Genet (2013) 0.79

Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice. Nat Commun (2015) 0.78

Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse. Mol Cell Proteomics (2014) 0.76

New Concepts and Mechanisms of Platelet Activation Signaling. Physiology (Bethesda) (2017) 0.75

Articles cited by this

Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature (1995) 9.86

Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin. Pharmacol Rev (1978) 4.66

Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium. Lancet (1987) 4.55

Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II. Science (1996) 3.01

Defective smooth muscle regulation in cGMP kinase I-deficient mice. EMBO J (1998) 2.96

cAMP- and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets. J Biol Chem (1994) 2.95

cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase. Proc Natl Acad Sci U S A (1996) 2.17

Platelet-endothelial cell interactions during ischemia/reperfusion: the role of P-selectin. Blood (1998) 1.65

Adhesion of activated platelets to endothelial cells: evidence for a GPIIbIIIa-dependent bridging mechanism and novel roles for endothelial intercellular adhesion molecule 1 (ICAM-1), alphavbeta3 integrin, and GPIbalpha. J Exp Med (1998) 1.61

Phosphorylation of focal adhesion vasodilator-stimulated phosphoprotein at Ser157 in intact human platelets correlates with fibrinogen receptor inhibition. Eur J Biochem (1994) 1.48

cGMP-dependent protein kinase mediates the reduction of Ca2+ by cAMP in vascular smooth muscle cells. Am J Physiol (1990) 1.43

Role of cGMP and cGMP-dependent protein kinase in nitrovasodilator inhibition of agonist-evoked calcium elevation in human platelets. Proc Natl Acad Sci U S A (1992) 1.40

The vascular biology of nitric oxide and its role in atherogenesis. Annu Rev Med (1996) 1.34

Demonstration of cGMP-dependent protein kinase and cGMP-dependent phosphorylation in cell-free extracts of platelets. Eur J Biochem (1986) 1.31

Nitric oxide released from activated platelets inhibits platelet recruitment. J Clin Invest (1997) 1.28

Inhibition of fibrinogen binding to human platelets by S-nitroso-N-acetylcysteine. J Biol Chem (1990) 1.28

Mechanism of platelet inhibition by nitric oxide: in vivo phosphorylation of thromboxane receptor by cyclic GMP-dependent protein kinase. Proc Natl Acad Sci U S A (1998) 1.23

Regulation of cytosolic calcium by cAMP and cGMP in freshly isolated smooth muscle cells from bovine trachea. J Biol Chem (1988) 1.13

Transfected cGMP-dependent protein kinase suppresses calcium transients by inhibition of inositol 1,4,5-trisphosphate production. Proc Natl Acad Sci U S A (1993) 1.10

Expression of cGMP-dependent protein kinase I and phosphorylation of its substrate, vasodilator-stimulated phosphoprotein, in human endothelial cells of different origin. Circ Res (1995) 1.10

Quantitative analysis of small intestinal microcirculation in the mouse. Res Exp Med (Berl) (1998) 1.00

Effects of nitric oxide/EDRF on platelet surface glycoproteins. Am J Physiol (1996) 0.99

Platelet shape change induced by thrombin receptor activation. Rapid stimulation of tyrosine phosphorylation of novel protein substrates through an integrin- and Ca(2+)-independent mechanism. J Biol Chem (1995) 0.98

Platelet and vascular function during coronary thrombolysis with tissue-type plasminogen activator. Circulation (1989) 0.95

Inhaled nitric oxide increases coronary artery patency after thrombolysis. Circulation (1996) 0.93

The focal adhesion phosphoprotein, VASP. Int J Biochem Cell Biol (1998) 0.92

Defective nitrovasodilator-stimulated protein phosphorylation and calcium regulation in cGMP-dependent protein kinase-deficient human platelets of chronic myelocytic leukemia. J Biol Chem (1993) 0.90

Prevention of arterial thrombosis by adenovirus-mediated transfer of cyclooxygenase gene. Circulation (1996) 0.88

Platelet-vessel wall interactions, focal adhesions, and the mechanism of action of endothelial factors. Agents Actions Suppl (1995) 0.86

Myocardial ischaemia induces platelet activation with adverse electrophysiological and arrhythmogenic effects. Cardiovasc Res (1994) 0.86

Platelet activation and interactions with the microvasculature. J Cardiovasc Pharmacol (1996) 0.86

Cyclic GMP but not cyclic AMP prevents renal platelet accumulation after ischemia-reperfusion in anesthetized rats. J Pharmacol Exp Ther (1994) 0.84

Effects of leukocyte and platelet depletion on ischemia--reperfusion injury to dog pancreas. Gastroenterology (1994) 0.82

Effects of depletion of leukocytes and platelets on cardiac dysfunction after cardiopulmonary bypass. Ann Thorac Surg (1998) 0.81

Importance of platelets in myocardial injury after reperfusion in the presence of residual coronary stenosis in dogs. Am Heart J (1993) 0.80

Enhancement of tissue-type plasminogen activator-induced thrombolysis and prevention of reocclusion by combination with a humanized anti-glycoprotein IIb/IIIa monoclonal antibody, YM337, in a rhesus monkey model of coronary thrombosis. Thromb Haemost (1998) 0.78

Inhibition of coronary artery reocclusion after thrombolysis with an RGD-containing peptide with no significant effect on bleeding time. Coron Artery Dis (1993) 0.78

Flow cytometry reveals activated GP IIb-IIIa complexes on platelets from patients undergoing thrombolytic therapy after acute myocardial infarction. Blood Coagul Fibrinolysis (1995) 0.78

Articles by these authors

WHO guidelines for the programmatic management of drug-resistant tuberculosis: 2011 update. Eur Respir J (2011) 8.96

Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer. N Engl J Med (1985) 8.45

Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity (1999) 8.33

Identification of tissue transglutaminase as the autoantigen of celiac disease. Nat Med (1997) 7.42

Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice. Nature (2003) 5.84

Prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic persons. N Engl J Med (1989) 5.78

Detection and in situ identification of representatives of a widely distributed new bacterial phylum. FEMS Microbiol Lett (1997) 5.20

A family of hyperpolarization-activated mammalian cation channels. Nature (1998) 4.97

The naming of voltage-gated calcium channels. Neuron (1994) 4.31

Complete genome sequence of the marine planctomycete Pirellula sp. strain 1. Proc Natl Acad Sci U S A (2003) 4.16

Relation of number of positive axillary nodes to the prognosis of patients with primary breast cancer. An NSABP update. Cancer (1983) 3.94

Negative regulation of fibroblast motility by Ena/VASP proteins. Cell (2000) 3.89

Primary structure and functional expression from complementary DNA of a brain calcium channel. Nature (1991) 3.77

Ten-year results of a randomized clinical trial comparing radical mastectomy and total mastectomy with or without radiation. N Engl J Med (1985) 3.41

Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytes. EMBO J (2000) 3.32

The accuracy of clinical nodal staging and of limited axillary dissection as a determinant of histologic nodal status in carcinoma of the breast. Surg Gynecol Obstet (1981) 3.11

Nomenclature of voltage-gated sodium channels. Neuron (2000) 3.10

Nomenclature of voltage-gated calcium channels. Neuron (2000) 3.09

ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2-and heregulin-deficient mice. Development (1997) 3.04

PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration. Cancer Res (2000) 3.02

Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis. Nat Med (2001) 3.01

Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II. Science (1996) 3.01

Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response. Mol Psychiatry (2004) 2.98

The roles of the subunits in the function of the calcium channel. Science (1991) 2.97

Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency. Proc Natl Acad Sci U S A (2004) 2.97

Defective smooth muscle regulation in cGMP kinase I-deficient mice. EMBO J (1998) 2.96

Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice. Nat Cell Biol (2001) 2.94

Perlecan maintains the integrity of cartilage and some basement membranes. J Cell Biol (1999) 2.94

On the mechanism of beta-adrenergic regulation of the Ca channel in the guinea-pig heart. Pflugers Arch (1985) 2.93

Serum antibodies to L-type calcium channels in patients with amyotrophic lateral sclerosis. N Engl J Med (1992) 2.86

Differential regulation of pro-inflammatory cytokines during wound healing in normal and glucocorticoid-treated mice. Cytokine (1996) 2.84

Ca2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase. Biochem J (1992) 2.68

Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O. Proc Natl Acad Sci U S A (2001) 2.67

The genome of Desulfotalea psychrophila, a sulfate-reducing bacterium from permanently cold Arctic sediments. Environ Microbiol (2004) 2.66

Idiopathic eosinophilic esophagitis is associated with a T(H)2-type allergic inflammatory response. J Allergy Clin Immunol (2001) 2.62

Absence of integrin alpha 7 causes a novel form of muscular dystrophy. Nat Genet (1997) 2.59

The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor. J Exp Med (1998) 2.55

Two pacemaker channels from human heart with profoundly different activation kinetics. EMBO J (1999) 2.51

Fetal and adult hematopoietic stem cells require beta1 integrin function for colonizing fetal liver, spleen, and bone marrow. Immunity (2000) 2.51

Cellular expression and functional characterization of four hyperpolarization-activated pacemaker channels in cardiac and neuronal tissues. Eur J Biochem (2001) 2.47

Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3. Proc Natl Acad Sci U S A (1999) 2.46

Beta 1 integrin-dependent and -independent polymerization of fibronectin. J Cell Biol (1996) 2.44

Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen. EMBO J (2001) 2.44

New views on RPE65 deficiency: the rod system is the source of vision in a mouse model of Leber congenital amaurosis. Nat Genet (2001) 2.44

A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment. J Cell Biol (2001) 2.42

Purified dihydropyridine-binding site from skeletal muscle t-tubules is a functional calcium channel. Nature (1986) 2.41

Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularization. Am J Pathol (2000) 2.41

Primary structure of the beta subunit of the DHP-sensitive calcium channel from skeletal muscle. Science (1989) 2.40

Fibromodulin-null mice have abnormal collagen fibrils, tissue organization, and altered lumican deposition in tendon. J Biol Chem (1999) 2.38

The role of the BK channel in potassium homeostasis and flow-induced renal potassium excretion. Kidney Int (2007) 2.37

Injection of subunits of cyclic AMP-dependent protein kinase into cardiac myocytes modulates Ca2+ current. Nature (1982) 2.33

Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions. Proc Natl Acad Sci U S A (1999) 2.33

Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture. Genes Dev (1997) 2.32

Modulation of Ca current during the phosphorylation cycle in the guinea pig heart. Pflugers Arch (1986) 2.26

Syncope: a videometric analysis of 56 episodes of transient cerebral hypoxia. Ann Neurol (1994) 2.19

Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Ibeta. Nature (2000) 2.17

Functional embryonic cardiomyocytes after disruption of the L-type alpha1C (Cav1.2) calcium channel gene in the mouse. J Biol Chem (2000) 2.09

Transfer of airway skills from manikin training to patient: success of ventilation with facemask or LMA-Supreme(TM) by medical students. Anaesthesia (2013) 2.09

Normalization of current kinetics by interaction between the alpha 1 and beta subunits of the skeletal muscle dihydropyridine-sensitive Ca2+ channel. Nature (1991) 2.09

Primary structure and functional expression of a high voltage activated calcium channel from rabbit lung. FEBS Lett (1990) 2.08

A common motif of eukaryotic glycosyltransferases is essential for the enzyme activity of large clostridial cytotoxins. J Biol Chem (1998) 2.08

Glutathionylation of the p50 subunit of NF-kappaB: a mechanism for redox-induced inhibition of DNA binding. Biochemistry (2001) 2.07

Structure and functional expression of a new member of the tetrodotoxin-sensitive voltage-activated sodium channel family from human neuroendocrine cells. EMBO J (1995) 2.06

Mutations in the gene encoding epsilon-sarcoglycan cause myoclonus-dystonia syndrome. Nat Genet (2001) 2.06

Regional expression and cellular localization of the alpha1 and beta subunit of high voltage-activated calcium channels in rat brain. J Neurosci (1997) 2.05

Neoadjuvant therapy of esophageal squamous cell carcinoma: response evaluation by positron emission tomography. Ann Surg (2001) 2.04

Early mycological treatment failure in AIDS-associated cryptococcal meningitis. Clin Infect Dis (1999) 2.04

Comparison of adenosine 3':5'-monophosphate-dependent protein kinases from rabbit skeletal and bovine heart muscle. J Biol Chem (1975) 2.03

Temporally controlled somatic mutagenesis in smooth muscle. Genesis (2000) 2.01

Transgenic knockouts reveal a critical requirement for pancreatic beta cell glucokinase in maintaining glucose homeostasis. Cell (1995) 1.99

[Monitoring of liver function in the critically ill]. Anaesthesist (2014) 1.99

Fluconazole combined with flucytosine for treatment of cryptococcal meningitis in patients with AIDS. Clin Infect Dis (1994) 1.99

Disruption of the talin gene arrests mouse development at the gastrulation stage. Dev Dyn (2000) 1.98

The vasodilator-stimulated phosphoprotein (VASP) is involved in cGMP- and cAMP-mediated inhibition of agonist-induced platelet aggregation, but is dispensable for smooth muscle function. EMBO J (1999) 1.95

Roles of integrins and fibronectin in the entry of Streptococcus pyogenes into cells via protein F1. Mol Microbiol (1998) 1.92

Calcium channel beta subunit heterogeneity: functional expression of cloned cDNA from heart, aorta and brain. EMBO J (1992) 1.92

Maternal and newborn vitamin D status and its impact on food allergy development in the German LINA cohort study. Allergy (2012) 1.88

Impaired migration but not differentiation of haematopoietic stem cells in the absence of beta1 integrins. Nature (1996) 1.87

Transgenic mice with targeted inactivation of the Col2 alpha 1 gene for collagen II develop a skeleton with membranous and periosteal bone but no endochondral bone. Genes Dev (1995) 1.86

[Generation Y : recruitment, retention and development]. Anaesthesist (2011) 1.86

B lymphocytes producing demyelinating autoantibodies: development and function in gene-targeted transgenic mice. J Exp Med (1998) 1.85

Does thyroid supplementation accelerate tricyclic antidepressant response? A review and meta-analysis of the literature. Am J Psychiatry (2001) 1.85

Transcriptomic and proteomic patterns of systemic inflammation in on-pump and off-pump coronary artery bypass grafting. Circulation (2005) 1.83