Published in Cell on December 12, 1997
Application of phage display to high throughput antibody generation and characterization. Genome Biol (2007) 1.98
Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses. PLoS One (2011) 1.69
Polyspecificity of T cell and B cell receptor recognition. Semin Immunol (2007) 1.68
Electrostatics in protein-protein docking. Protein Sci (2002) 1.30
Characterization of a conformational epitope on hepatitis B virus core antigen and quasiequivalent variations in antibody binding. J Virol (2003) 1.29
On a mouse monoclonal antibody that neutralizes all four dengue virus serotypes. J Gen Virol (2009) 1.11
By-passing selection: direct screening for antibody-antigen interactions using protein arrays. Nucleic Acids Res (2000) 1.09
High affinity antigen recognition of the dual specific variants of herceptin is entropy-driven in spite of structural plasticity. PLoS One (2011) 1.03
Epitope mapping of trans-sialidase from Trypanosoma cruzi reveals the presence of several cross-reactive determinants. Infect Immun (2001) 1.02
Immunoblot analysis of CD34 expression in histologically diverse neoplasms. Am J Pathol (2000) 0.99
Polyreactive antigen-binding B (PAB-) cells are widely distributed and the PAB population consists of both B-1+ and B-1- phenotypes. Clin Exp Immunol (2004) 0.91
Epitope-specificity of recombinant antibodies reveals promiscuous peptide-binding properties. Protein Sci (2012) 0.84
Peptides that bind specifically to an antibody from a chronic lymphocytic leukemia clone expressing unmutated immunoglobulin variable region genes. Mol Med (2013) 0.82
Thermodynamic stability and flexibility characteristics of antibody fragment complexes. Protein Pept Lett (2014) 0.82
Evolutionary transition pathways for changing peptide ligand specificity and structure. EMBO J (2000) 0.80
Plasticity in protein-peptide recognition: crystal structures of two different peptides bound to concanavalin A. Biophys J (2001) 0.79
Antibody Binding Selectivity: Alternative Sets of Antigen Residues Entail High-Affinity Recognition. PLoS One (2015) 0.77
Immunodominant West Nile Virus T Cell Epitopes Are Fewer in Number and Fashionably Late. J Immunol (2016) 0.75
Molecular Mechanism and Energy Basis of Conformational Diversity of Antibody SPE7 Revealed by Molecular Dynamics Simulation and Principal Component Analysis. Sci Rep (2016) 0.75
Structure of a novel shoulder-to-shoulder p24 dimer in complex with the broad-spectrum antibody A10F9 and its implication in capsid assembly. PLoS One (2013) 0.75
Substrate specificity of the DnaK chaperone determined by screening cellulose-bound peptide libraries. EMBO J (1997) 4.28
T-cell epitope mapping by flow cytometry. Nat Med (1998) 2.56
Target structures of the CD8(+)-T-cell response to human cytomegalovirus: the 72-kilodalton major immediate-early protein revisited. J Virol (1999) 2.55
Low density lipoprotein receptor as a candidate receptor for hepatitis C virus. J Med Virol (1999) 2.52
The GroE chaperonin machine is a major modulator of the CIRCE heat shock regulon of Bacillus subtilis. EMBO J (1997) 2.50
Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia. Nat Genet (2001) 2.39
FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase. Cell (1996) 2.15
ClpS is an essential component of the N-end rule pathway in Escherichia coli. Nature (2006) 2.09
Its substrate specificity characterizes the DnaJ co-chaperone as a scanning factor for the DnaK chaperone. EMBO J (2001) 1.94
Predictors of systolic augmentation from left ventricular preexcitation in patients with dilated cardiomyopathy and intraventricular conduction delay. Circulation (2000) 1.89
Regulatory region C of the E. coli heat shock transcription factor, sigma32, constitutes a DnaK binding site and is conserved among eubacteria. J Mol Biol (1996) 1.85
Incidence of atrial flutter/fibrillation in adults with atrial septal defect before and after surgery. Ann Thorac Surg (1999) 1.84
Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand. Immunity (1995) 1.83
Coherent membrane supports for parallel microsynthesis and screening of bioactive peptides. Biopolymers (2000) 1.82
Impact of cardiac resynchronization therapy using hemodynamically optimized pacing on left ventricular remodeling in patients with congestive heart failure and ventricular conduction disturbances. J Am Coll Cardiol (2001) 1.80
Applications of peptide arrays prepared by the SPOT-technology. Curr Opin Biotechnol (2001) 1.79
Performance of concurrent tasks: a psychophysiological analysis of the reciprocity of information-processing resources. Science (1983) 1.75
Synthesis and screening of peptide libraries on continuous cellulose membrane supports. Methods Mol Biol (1998) 1.74
Bilateral skeletonized internal thoracic artery grafts in patients with diabetes mellitus. J Thorac Cardiovasc Surg (2001) 1.69
Using flexible loop mimetics to extend phi-value analysis to secondary structure interactions. Proc Natl Acad Sci U S A (2001) 1.69
The activation of female sex hormones: alpha-Oestradiol and its di-esters. Biochem J (1938) 1.69
Recommendations for surgical hand disinfection -- requirements, implementation and need for research. A proposal by representatives of the SFHH, DGHM and DGKH for a European discussion. J Hosp Infect (2002) 1.63
Standardized comparison of antiseptic efficacy of triclosan, PVP-iodine, octenidine dihydrochloride, polyhexanide and chlorhexidine digluconate. J Antimicrob Chemother (2010) 1.54
Mutational analysis of acute-phase response factor/Stat3 activation and dimerization. Mol Cell Biol (1997) 1.51
Distribution of binding sequences for the mitochondrial import receptors Tom20, Tom22, and Tom70 in a presequence-carrying preprotein and a non-cleavable preprotein. J Biol Chem (1999) 1.50
The activation of female sex hormones: Oestrone and its esters. The output of activity and efficiency coefficient. Biochem J (1938) 1.49
[Influence of floor disinfection on microbial and particulate burden measured under low turbulance air flow in ophthalmological operation theatres]. Klin Monbl Augenheilkd (2010) 1.49
Binding specificity of Escherichia coli trigger factor. Proc Natl Acad Sci U S A (2001) 1.45
New evidence for the role of TNF-alpha in liver ischaemic/reperfusion injury. Eur J Clin Invest (2008) 1.43
Specific interactions between the syntrophin PDZ domain and voltage-gated sodium channels. Nat Struct Biol (1998) 1.43
Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinity. EMBO J (2000) 1.40
ACTH-induced adrenal hemorrhage: a complication of therapy masquerading as an acute abdomen. J Clin Gastroenterol (1990) 1.40
Loss of caspase-1 and caspase-3 protein expression in human prostate cancer. Cancer Res (2001) 1.35
Molecular basis for the binding promiscuity of an anti-p24 (HIV-1) monoclonal antibody. Cell (1997) 1.35
Review on the efficacy, safety and clinical applications of polihexanide, a modern wound antiseptic. Skin Pharmacol Physiol (2010) 1.33
Extracellular ATP and TNF-alpha synergize in the activation and maturation of human dendritic cells. J Immunol (2000) 1.31
Quantitation of hepatitis C virus RNA by third generation branched DNA-based signal amplification assay. J Virol Methods (2002) 1.30
Anti-tumor necrosis factor-alpha improves myocardial recovery after ischemia and reperfusion. J Am Coll Cardiol (1997) 1.29
Prevention and control of health care-associated waterborne infections in health care facilities. Am J Infect Control (2005) 1.25
Effectiveness of basic clinical skills training programmes: a cross-sectional comparison of four medical schools. Med Educ (2001) 1.24
The SH3 domains of endophilin and amphiphysin bind to the proline-rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity. J Biol Chem (1999) 1.24
Failure of potassium siphoning by Müller cells: a new hypothesis of perfluorocarbon liquid-induced retinopathy. Invest Ophthalmol Vis Sci (2000) 1.22
Dissociation of the signalling and antiviral properties of SDF-1-derived small peptides. Curr Biol (1998) 1.22
Complementary and alternative therapeutic approaches in patients with early breast cancer: a systematic review. Breast Cancer Res Treat (2006) 1.21
Modular structure of the trigger factor required for high activity in protein folding. J Mol Biol (1997) 1.21
Shared usage of the chemokine receptor CXCR4 by primary and laboratory-adapted strains of feline immunodeficiency virus. J Virol (1999) 1.20
Antimicrobial efficacy of antiseptic mouthrinse solutions. Eur J Clin Pharmacol (1999) 1.20
Slit-lamp-adapted optical coherence tomography of the anterior segment. Graefes Arch Clin Exp Ophthalmol (2000) 1.19
The effect of a polyhexamethylene biguanide mouthrinse compared to an essential oil rinse and a chlorhexidine rinse on bacterial counts and 4-day plaque regrowth. J Clin Periodontol (2002) 1.19
[Clinical practice guideline on diagnosis and treatment of Crohn's disease]. Z Gastroenterol (2008) 1.19
Digital X-ray radiogrammetry combined with semiautomated analysis of joint space widths as a new diagnostic approach in rheumatoid arthritis: a cross-sectional and longitudinal study. Arthritis Rheum (2005) 1.18
Hydrogen peroxide: A central player in physical plasma-induced oxidative stress in human blood cells. Free Radic Res (2014) 1.17
Tumor cell lysate-pulsed human dendritic cells induce a T-cell response against pancreatic carcinoma cells: an in vitro model for the assessment of tumor vaccines. Cancer Res (2001) 1.17
Asthma and allergies among children in West and East Germany: a comparison between Münster and Greifswald using the ISAAC phase I protocol. International Study of Asthma and Allergies in Childhood. Eur Respir J (1998) 1.16
[The efficacy of repeated disinfection of disposable gloves during usage]. Zentralbl Hyg Umweltmed (1999) 1.16
Immunosuppressive treatment of chronic periaortitis: a retrospective study of 20 patients with chronic periaortitis and a review of the literature. Ann Rheum Dis (2005) 1.15
Transvenous biventricular pacing for heart failure: can the obstacles be overcome? Am J Cardiol (1999) 1.13
A novel epitope on the C-terminus of SmD1 is recognized by the majority of sera from patients with systemic lupus erythematosus. J Clin Invest (1998) 1.12
Spot synthesis: observations and optimizations. J Pept Res (1999) 1.12
Testing for multiple species in fossil samples: an evaluation and comparison of tests for equal relative variation. Am J Phys Anthropol (1999) 1.11
Substrate specificity of the SecB chaperone. J Biol Chem (1999) 1.11
Modulation of substrate specificity of the DnaK chaperone by alteration of a hydrophobic arch. J Mol Biol (2000) 1.11
Should stimulation site be tailored in the individual heart failure patient? Am J Cardiol (2000) 1.11
Dominantly inherited renal adysplasia. Am J Med Genet (1987) 1.11
Dynamic association of trigger factor with protein substrates. J Mol Biol (2001) 1.11
Skin disinfection by plasma-tissue interaction: comparison of the effectivity of tissue-tolerable plasma and a standard antiseptic. Skin Pharmacol Physiol (2011) 1.10
Octenidine dihydrochloride, a modern antiseptic for skin, mucous membranes and wounds. Skin Pharmacol Physiol (2010) 1.09
[Methodological basis for the development of consensus recommendations]. Z Gastroenterol (2004) 1.09
Role of phosphorylation in the mammalian circadian clock. Cold Spring Harb Symp Quant Biol (2007) 1.08
Corneal optical coherence tomography before and immediately after excimer laser photorefractive keratectomy. Am J Ophthalmol (2000) 1.08
Atomic resolution structure of native porcine pancreatic elastase at 1.1 A. Acta Crystallogr D Biol Crystallogr (2000) 1.07
Antigen sequence- and library-based mapping of linear and discontinuous protein-protein-interaction sites by spot synthesis. Curr Top Microbiol Immunol (1999) 1.07
The integrity of latex gloves in clinical dental practice. Infection (2001) 1.07
X-ray structure of the quinoprotein ethanol dehydrogenase from Pseudomonas aeruginosa: basis of substrate specificity. J Mol Biol (2000) 1.06
Cross-reactivity of myelin basic protein-specific T cells with multiple microbial peptides: experimental autoimmune encephalomyelitis induction in TCR transgenic mice. J Immunol (1999) 1.06
Respiratory syncytial virus immune globulin treatment of RSV lower respiratory tract infection in previously healthy children. Pediatrics (1997) 1.05
A standardized test to assess the impact of different organic challenges on the antimicrobial activity of antiseptics. J Hosp Infect (2003) 1.04
The mitochondrial import receptor Tom70: identification of a 25 kDa core domain with a specific binding site for preproteins. J Mol Biol (2000) 1.04
High affinity endotoxin-binding and neutralizing peptides based on the crystal structure of recombinant Limulus anti-lipopolysaccharide factor. J Biol Chem (1996) 1.04
Antimicrobial effectiveness of povidone-iodine and consequences for new application areas. Dermatology (2002) 1.04
Synthetic endotoxin-binding peptides block endotoxin-triggered TNF-alpha production by macrophages in vitro and in vivo and prevent endotoxin-mediated toxic shock. J Immunol (2000) 1.01
Peripheral bone status in rheumatoid arthritis evaluated by digital X-ray radiogrammetry and compared with multisite quantitative ultrasound. Calcif Tissue Int (2006) 1.00
Risk factors for systemic embolism in patients with paroxysmal atrial fibrillation. Am Heart J (1992) 1.00
Polarized ion transport during migration of transformed Madin-Darby canine kidney cells. Pflugers Arch (1995) 0.99
Anti-c-myc antibody 9E10: epitope key positions and variability characterized using peptide spot synthesis on cellulose. Protein Eng (2001) 0.99
Tracer test with As(V) under variable redox conditions controlling arsenic transport in the presence of elevated ferrous iron concentrations. J Contam Hydrol (2006) 0.99
Conformation, pH-induced conformational changes, and thermal unfolding of anti-p24 (HIV-1) monoclonal antibody CB4-1 and its Fab and Fc fragments. Biochim Biophys Acta (1999) 0.99
Characterization and binding specificity of the monomeric STAT3-SH2 domain. J Biol Chem (1999) 0.98
[Diagnosis and therapy of ulcerative colitis: results of an evidence based consensus conference by the German society of Digestive and Metabolic Diseases and the competence network on inflammatory bowel disease]. Z Gastroenterol (2004) 0.97
Cyclophilin and trigger factor from Bacillus subtilis catalyze in vitro protein folding and are necessary for viability under starvation conditions. Biochemistry (1998) 0.97
Mapping protein-protein contact sites using cellulose-bound peptide scans. Mol Divers (1996) 0.97