Published in J Clin Invest on January 01, 1998
Platelet PECAM-1 inhibits thrombus formation in vivo. Blood (2005) 1.53
Endothelial cell E- and P-selectin and vascular cell adhesion molecule-1 function as signaling receptors. J Cell Biol (1998) 1.52
Streptavidin facilitates internalization and pulmonary targeting of an anti-endothelial cell antibody (platelet-endothelial cell adhesion molecule 1): a strategy for vascular immunotargeting of drugs. Proc Natl Acad Sci U S A (1999) 1.46
PECAM-1 (CD31) expression modulates bleeding time in vivo. Am J Pathol (2000) 1.36
PECAM-1: conflicts of interest in inflammation. Life Sci (2010) 1.30
A new role for the muscle repair protein dysferlin in endothelial cell adhesion and angiogenesis. Arterioscler Thromb Vasc Biol (2010) 1.01
Collaborative enhancement of antibody binding to distinct PECAM-1 epitopes modulates endothelial targeting. PLoS One (2012) 0.98
Minimal regulation of platelet activity by PECAM-1. Platelets (2007) 0.86
PECAM-1 (CD31) regulates a hydrogen peroxide-activated nonselective cation channel in endothelial cells. J Cell Biol (2002) 0.86
TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response. J Exp Med (2015) 0.86
Ox-LDL promotes migration and adhesion of bone marrow-derived mesenchymal stem cells via regulation of MCP-1 expression. Mediators Inflamm (2013) 0.85
PMN transendothelial migration decreases nuclear NFkappaB in IL-1beta-activated endothelial cells: role of PECAM-1. J Cell Biol (2003) 0.83
An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling. J Cell Sci (2008) 0.83
The CD38/CD157 mammalian gene family: An evolutionary paradigm for other leukocyte surface enzymes. Purinergic Signal (2006) 0.78
Human neutrophils specifically interact with human monocyte-derived macrophage monolayers. Inflammation (2000) 0.78
Molecular engineering of high affinity single-chain antibody fragment for endothelial targeting of proteins and nanocarriers in rodents and humans. J Control Release (2016) 0.76
A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem (1985) 90.20
PECAM-1 is required for transendothelial migration of leukocytes. J Exp Med (1993) 4.81
Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule. J Cell Biol (1991) 3.91
Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140. J Biol Chem (1989) 3.34
Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo. Science (1993) 2.71
Regulation of vascular endothelial barrier function. Am J Physiol (1994) 2.40
Endothelial cell cytosolic free calcium regulates neutrophil migration across monolayers of endothelial cells. J Cell Biol (1993) 2.23
Involvement of endothelial PECAM-1/CD31 in angiogenesis. Am J Pathol (1997) 2.17
Molecular and functional aspects of PECAM-1/CD31. Immunol Today (1994) 2.04
The biology of PECAM-1. J Clin Invest (1997) 2.01
Evidence that agonists stimulate bivalent-cation influx into human endothelial cells. Biochem J (1988) 1.87
Involvement of myosin light-chain kinase in endothelial cell retraction. Proc Natl Acad Sci U S A (1990) 1.82
Identification and characterization of cell-substratum adhesion receptors on cultured human endothelial cells. J Clin Invest (1989) 1.75
Monocyte-selective transendothelial migration: dissection of the binding and transmigration phases by an in vitro assay. J Exp Med (1992) 1.72
Roles of platelet/endothelial cell adhesion molecule-1 (PECAM-1, CD31) in natural killer cell transendothelial migration and beta 2 integrin activation. J Immunol (1996) 1.51
Individually distinct Ig homology domains in PECAM-1 regulate homophilic binding and modulate receptor affinity. J Biol Chem (1996) 1.50
Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression. J Biol Chem (1996) 1.37
Intracellular calcium, currents, and stimulus-response coupling in endothelial cells. Hypertension (1993) 1.35
Cyclooxygenase-dependent formation of the isoprostane, 8-epi prostaglandin F2 alpha. J Biol Chem (1995) 1.28
Localization of multiple functional domains on human PECAM-1 (CD31) by monoclonal antibody epitope mapping. Cell Adhes Commun (1995) 1.27
Integrin engagement mediates tyrosine dephosphorylation on platelet-endothelial cell adhesion molecule 1. Proc Natl Acad Sci U S A (1996) 1.25
Deletions in the cytoplasmic domain of platelet-endothelial cell adhesion molecule-1 (PECAM-1, CD31) result in changes in ligand binding properties. J Cell Biol (1994) 1.23
Platelet endothelial cell adhesion molecule, PECAM-1, modulates cell migration. J Cell Physiol (1992) 1.22
Regulation of extracellular calcium entry in endothelial cells: role of intracellular calcium pool. Am J Physiol (1992) 1.21
Bradykinin induces elevations of cytosolic calcium through mobilisation of intracellular and extracellular pools in bovine aortic endothelial cells. Br J Pharmacol (1991) 1.11
Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: an effective in vitro drug sensitization system. Cancer Res (1994) 1.09
Measurement of cytoplasmic calcium in single microvessels with increased permeability. Am J Physiol (1990) 1.06
alpha-Thrombin increases cytosolic calcium and induces human airway smooth muscle cell proliferation. Am J Respir Cell Mol Biol (1995) 1.04
Inositol phosphate production and Ca2+ mobilization in human umbilical-vein endothelial cells stimulated by thrombin and histamine. Biochem J (1988) 1.02
Human CD38 ligand. A 120-KDA protein predominantly expressed on endothelial cells. J Immunol (1996) 1.00
Prolonged peak elevations in cytoplasmic free calcium ions, derived from intracellular stores, correlate with the extent of thrombin-stimulated exocytosis in single human umbilical vein endothelial cells. J Cell Physiol (1994) 0.98
Influence of vasoactive agents on cytoplasmic free calcium in vascular endothelial cells. J Appl Physiol (1985) (1988) 0.97
Calcium dependence of the thrombin-induced increase in endothelial albumin permeability. J Appl Physiol (1985) (1989) 0.97
The platelet endothelial cell adhesion molecule-1 (PECAM1) contributes to endothelial barrier function. FEBS Lett (1995) 0.96
Calcium and the cytoskeleton. Br Med Bull (1986) 0.92
CD50 (intercellular adhesion molecule 3) stimulation induces calcium mobilization and tyrosine phosphorylation through p59fyn and p56lck in Jurkat T cell line. J Exp Med (1994) 0.89
CD31-triggered rearrangement of the actin cytoskeleton in human natural killer cells. Eur J Immunol (1996) 0.85
A novel monoclonal antibody against carbohydrates of L1 cell adhesion molecule causes an influx of calcium in cultured cortical neurons. Brain Res (1992) 0.79
Intracellular calcium levels are differentially regulated in T lymphocytes triggered by anti-CD2 and anti-CD3 monoclonal antibodies. Cell Signal (1995) 0.77
The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy. Nature (1991) 5.40
Maximal migration of human smooth muscle cells on fibronectin and type IV collagen occurs at an intermediate attachment strength. J Cell Biol (1993) 3.74
Biochemical markers in persons with preclinical familial Alzheimer disease. Neurology (2008) 3.54
Dual time point 18F-FDG PET imaging for differentiating malignant from inflammatory processes. J Nucl Med (2001) 3.24
Longitudinal CSF and MRI biomarkers improve the diagnosis of mild cognitive impairment. Neurobiol Aging (2005) 3.00
Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Development (1994) 2.71
Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo. Science (1993) 2.71
CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion. J Exp Med (1992) 2.38
Involvement of endothelial PECAM-1/CD31 in angiogenesis. Am J Pathol (1997) 2.17
Sphingosine 1-phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma. FASEB J (2001) 2.15
Imaging and CSF studies in the preclinical diagnosis of Alzheimer's disease. Ann N Y Acad Sci (2007) 2.11
Selected contribution: time course and heterogeneity of contractile responses in cultured human airway smooth muscle cells. J Appl Physiol (1985) (2001) 2.07
Molecular and functional aspects of PECAM-1/CD31. Immunol Today (1994) 2.04
Metabolic imaging of malignant pleural mesothelioma with fluorodeoxyglucose positron emission tomography. Chest (1998) 1.91
Transcellular activation of platelets and endothelial cells by bioactive lipids in platelet microparticles. J Clin Invest (1997) 1.90
Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma. Ann Thorac Surg (1994) 1.89
MRI and CSF studies in the early diagnosis of Alzheimer's disease. J Intern Med (2004) 1.77
Prognostic value of FDG PET imaging in malignant pleural mesothelioma. J Nucl Med (1999) 1.67
Inflammatory and contractile agents sensitize specific adenylyl cyclase isoforms in human airway smooth muscle. Am J Respir Cell Mol Biol (1999) 1.62
An anti-platelet-endothelial cell adhesion molecule-1 antibody inhibits leukocyte extravasation from mesenteric microvessels in vivo by blocking the passage through the basement membrane. J Exp Med (1996) 1.58
Murine platelet endothelial cell adhesion molecule (PECAM-1)/CD31 modulates beta 2 integrins on lymphokine-activated killer cells. Eur J Immunol (1993) 1.58
Platelet/endothelial cell adhesion molecule-1 (CD31)-mediated cellular aggregation involves cell surface glycosaminoglycans. J Biol Chem (1993) 1.55
T lymphocytes adhere to airway smooth muscle cells via integrins and CD44 and induce smooth muscle cell DNA synthesis. J Exp Med (1994) 1.55
A heterophilic adhesion mechanism for platelet/endothelial cell adhesion molecule 1 (CD31). J Exp Med (1992) 1.55
Impact of preexisting and induced humoral and cellular immune responses in an adenovirus-based gene therapy phase I clinical trial for localized mesothelioma. Hum Gene Ther (1998) 1.51
Individually distinct Ig homology domains in PECAM-1 regulate homophilic binding and modulate receptor affinity. J Biol Chem (1996) 1.50
Direct effects of interleukin-13 on signaling pathways for physiological responses in cultured human airway smooth muscle cells. Am J Respir Crit Care Med (2001) 1.49
Integrin adhesion molecules in the human endometrium. Correlation with the normal and abnormal menstrual cycle. J Clin Invest (1992) 1.48
Streptavidin facilitates internalization and pulmonary targeting of an anti-endothelial cell antibody (platelet-endothelial cell adhesion molecule 1): a strategy for vascular immunotargeting of drugs. Proc Natl Acad Sci U S A (1999) 1.46
Human/severe combined immunodeficient mouse chimeras. An experimental in vivo model system to study the regulation of human endothelial cell-leukocyte adhesion molecules. J Clin Invest (1993) 1.42
Activation of K-p21ras and N-p21ras, but not H-p21ras, is necessary for mitogen-induced human airway smooth-muscle proliferation. Am J Respir Cell Mol Biol (1999) 1.42
8-epi PGF2 alpha generation during coronary reperfusion. A potential quantitative marker of oxidant stress in vivo. Circulation (1997) 1.41
Longitudinal CSF isoprostane and MRI atrophy in the progression to AD. J Neurol (2007) 1.41
Growth and invasion of human melanomas in human skin grafted to immunodeficient mice. Am J Pathol (1993) 1.39
Vitamin D inhibits growth of human airway smooth muscle cells through growth factor-induced phosphorylation of retinoblastoma protein and checkpoint kinase 1. Br J Pharmacol (2009) 1.37
Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression. J Biol Chem (1996) 1.37
Distribution of integrin cell adhesion receptors on normal bronchial epithelial cells and lung cancer cells in vitro and in vivo. Am J Respir Cell Mol Biol (1993) 1.37
Spatiotemporal segregation of endothelial cell integrin and nonintegrin extracellular matrix-binding proteins during adhesion events. J Cell Biol (1990) 1.32
Basic fibroblast growth factor modulates integrin expression in microvascular endothelial cells. Mol Biol Cell (1993) 1.31
Distribution of integrin cell adhesion receptors in normal and malignant lung tissue. Am J Respir Cell Mol Biol (1992) 1.31
Association of murine CD31 with transmigrating lymphocytes following antigenic stimulation. Am J Pathol (1992) 1.30
Antibodies against the first Ig-like domain of human platelet endothelial cell adhesion molecule-1 (PECAM-1) that inhibit PECAM-1-dependent homophilic adhesion block in vivo neutrophil recruitment. J Immunol (2000) 1.29
Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma. Hum Gene Ther (1998) 1.29
MAPK superfamily activation in human airway smooth muscle: mitogenesis requires prolonged p42/p44 activation. Am J Physiol (1999) 1.29
Regulation of extracellular matrix proteins and integrin cell substratum adhesion receptors on epithelium during cutaneous human wound healing in vivo. Am J Pathol (1993) 1.28
Pharmacological inhibition of protein kinases in intact cells: antagonism of beta adrenergic receptor ligand binding by H-89 reveals limitations of usefulness. J Pharmacol Exp Ther (1999) 1.27
Localization of multiple functional domains on human PECAM-1 (CD31) by monoclonal antibody epitope mapping. Cell Adhes Commun (1995) 1.27
Deletions in the cytoplasmic domain of platelet-endothelial cell adhesion molecule-1 (PECAM-1, CD31) result in changes in ligand binding properties. J Cell Biol (1994) 1.23
Platelet endothelial cell adhesion molecule, PECAM-1, modulates cell migration. J Cell Physiol (1992) 1.22
Regulation of mouse PECAM-1 tyrosine phosphorylation by the Src and Csk families of protein-tyrosine kinases. J Biol Chem (1998) 1.21
Diagnostic utility of pleural fluid eosinophilia. Am J Med (1984) 1.20
Arrestin specificity for G protein-coupled receptors in human airway smooth muscle. J Biol Chem (2001) 1.20
Tuberculous pleural effusions. Chest (1987) 1.19
Mechanisms of acute desensitization of the beta2AR-adenylyl cyclase pathway in human airway smooth muscle. Am J Respir Cell Mol Biol (1998) 1.18
Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation. Am J Physiol (1999) 1.18
Diet-induced hyperhomocysteinemia increases amyloid-beta formation and deposition in a mouse model of Alzheimer's disease. Curr Alzheimer Res (2010) 1.18
Activation of tumor necrosis factor receptor 1 in airway smooth muscle: a potential pathway that modulates bronchial hyper-responsiveness in asthma? Respir Res (2000) 1.17
Eradication of intraperitoneal and distant tumor by adenovirus-mediated interferon-beta gene therapy is attributable to induction of systemic immunity. Cancer Res (2001) 1.17
Aspergillus fumigatus-induced allergic airway inflammation alters surfactant homeostasis and lung function in BALB/c mice. Am J Respir Cell Mol Biol (2001) 1.15
Alternative splicing of a specific cytoplasmic exon alters the binding characteristics of murine platelet/endothelial cell adhesion molecule-1 (PECAM-1). J Biol Chem (1995) 1.15
Mechanisms underlying TNF-alpha effects on agonist-mediated calcium homeostasis in human airway smooth muscle cells. Am J Physiol (1997) 1.13
Adhesion molecules in the lung. An overview. Am Rev Respir Dis (1993) 1.13
The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis. Oncogene (2012) 1.13
Advances in the treatment of malignant pleural mesothelioma. Chest (1999) 1.11
Use of carrier cells to deliver a replication-selective herpes simplex virus-1 mutant for the intraperitoneal therapy of epithelial ovarian cancer. Clin Cancer Res (1999) 1.11
Susceptibility to ozone-induced airway inflammation is associated with decreased levels of surfactant protein D. Respir Res (2006) 1.10
Changes in plasma gelsolin concentration during acute oxidant lung injury in mice. Lung (2002) 1.09
Contributions of the extracellular and cytoplasmic domains of platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) in regulating cell-cell localization. J Cell Sci (2000) 1.09
Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: an effective in vitro drug sensitization system. Cancer Res (1994) 1.09
Activation of the TNF alpha-p55 receptor induces myocyte proliferation and modulates agonist-evoked calcium transients in cultured human tracheal smooth muscle cells. Am J Respir Cell Mol Biol (1996) 1.09
Expression of integrin cell adhesion receptors during human airway epithelial repair in vivo. Am J Physiol (1997) 1.08
Cytoplasmic and transmembrane domains of integrin beta 1 and beta 3 subunits are functionally interchangeable. J Cell Biol (1991) 1.08
Severe hemoptysis associated with pulmonary aspergilloma. Percutaneous intracavitary treatment. Chest (1988) 1.07
Platelet endothelial cell adhesion molecule (CD31). Curr Top Microbiol Immunol (1993) 1.07
A comprehensive educational program improves clinical outcome measures in inner-city patients with asthma. Arch Intern Med (1999) 1.07
Ozone inhalation induces exacerbation of eosinophilic airway inflammation and hyperresponsiveness in allergen-sensitized mice. Allergy (2008) 1.07
TNF-alpha induced CD38 expression in human airway smooth muscle cells: role of MAP kinases and transcription factors NF-kappaB and AP-1. Am J Physiol Lung Cell Mol Physiol (2007) 1.05
Tumor necrosis factor receptor (TNFR) 1, but not TNFR2, mediates tumor necrosis factor-alpha-induced interleukin-6 and RANTES in human airway smooth muscle cells: role of p38 and p42/44 mitogen-activated protein kinases. Mol Pharmacol (2001) 1.05
Up-regulation of ICAM-1 by cytokines in human tracheal smooth muscle cells involves an NF-kappa B-dependent signaling pathway that is only partially sensitive to dexamethasone. J Immunol (1999) 1.04
Mechanisms of proliferation synergy by receptor tyrosine kinase and G protein-coupled receptor activation in human airway smooth muscle. Am J Respir Cell Mol Biol (2000) 1.04
Expression of platelet-endothelial cell adhesion molecule-1 (PECAM-1) during melanoma-induced angiogenesis in vivo. J Cutan Pathol (1993) 1.04
Pharmacological activation changes stiffness of cultured human airway smooth muscle cells. Am J Physiol (1996) 1.03
TGF-beta 1 modulates EGF-stimulated phosphatidylinositol 3-kinase activity in human airway smooth muscle cells. Am J Physiol (1997) 1.03
Polymorphism of the beta(2)-adrenergic receptor gene and desensitization in human airway smooth muscle. Am J Respir Crit Care Med (2000) 1.02
Blockade of platelet endothelial cell adhesion molecule-1 protects against myocardial ischemia and reperfusion injury in cats. J Immunol (1996) 1.02
The GPCR OGR1 (GPR68) mediates diverse signalling and contraction of airway smooth muscle in response to small reductions in extracellular pH. Br J Pharmacol (2012) 1.02
Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth-muscle cells. Modulation by cyclic adenosine monophosphate. Am J Respir Cell Mol Biol (2000) 1.02
Role of fiberoptic bronchoscopy in the diagnosis of invasive pulmonary aspergillosis in patients with acute leukemia. Am J Med (1984) 1.01
Pleural thickening: its significance and relationship to asbestos dust exposure. Am Rev Respir Dis (1982) 1.01
Diffuse pulmonary hemorrhage: a review and classification. Radiology (1985) 1.00
Using macrophage activation to augment immunotherapy of established tumours. Br J Cancer (2013) 1.00
Gap junctions play a role in the 'bystander effect' of the herpes simplex virus thymidine kinase/ganciclovir system in vitro. Gene Ther (1996) 1.00
Platelet-derived growth factor-BB and thrombin activate phosphoinositide 3-kinase and protein kinase B: role in mediating airway smooth muscle proliferation. Mol Pharmacol (1998) 1.00
Pulmonary cavitation and massive hemoptysis in invasive pulmonary aspergillosis. Influence of bone marrow recovery in patients with acute leukemia. Am Rev Respir Dis (1985) 1.00
Comparative action of new highly potent bradykinin receptor antagonists in the guinea-pig trachea. Eur J Pharmacol (1993) 0.99
Neoadjuvant in situ gene-mediated cytotoxic immunotherapy improves postoperative outcomes in novel syngeneic esophageal carcinoma models. Cancer Gene Ther (2011) 0.99