Published in Neuroreport on December 01, 1997
Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas. Proc Natl Acad Sci U S A (2000) 5.49
Functional coexpression of HSV-1 thymidine kinase and green fluorescent protein: implications for noninvasive imaging of transgene expression. Neoplasia (1999) 1.44
BAC-VAC, a novel generation of (DNA) vaccines: A bacterial artificial chromosome (BAC) containing a replication-competent, packaging-defective virus genome induces protective immunity against herpes simplex virus 1. Proc Natl Acad Sci U S A (1999) 1.26
In Vivo Cellular Imaging for Translational Medical Research. Curr Med Imaging Rev (2009) 1.12
HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part II. Vector systems and applications. Neoplasia (1999) 0.88
Cord blood endothelial progenitor cells as therapeutic and imaging probes. Imaging Med (2012) 0.82
Inhibition of herpes simplex virus type 1 replication by adeno-associated virus rep proteins depends on their combined DNA-binding and ATPase/helicase activities. J Virol (2010) 0.81
Imaging and therapy of experimental schwannomas using HSV amplicon vector-encoding apoptotic protein under Schwann cell promoter. Cancer Gene Ther (2009) 0.81
Utility of a herpes oncolytic virus for the detection of neural invasion by cancer. Neoplasia (2008) 0.81
Genetic modification of cancer cells using non-viral, episomal S/MAR vectors for in vivo tumour modelling. PLoS One (2012) 0.79
Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication. PLoS One (2017) 0.75
A herpes simplex viral vector expressing green fluorescent protein can be used to visualize morphological changes in high-density neuronal culture. Electron J Biotechnol (2001) 0.75
Silicone rubber substrata: a new wrinkle in the study of cell locomotion. Science (1980) 9.81
Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas. Proc Natl Acad Sci U S A (2000) 5.49
The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein. Nat Genet (1997) 5.39
Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A. Science (1993) 5.05
Ferritin in the serum of normal subjects and patients with iron deficiency and iron overload. Br Med J (1972) 4.60
Ferritin in serum. Clinical and biochemical implications. N Engl J Med (1975) 4.51
An immunoradiometric assay for ferritin in the serum of normal subjects and patients with iron deficiency and iron overload. J Clin Pathol (1972) 4.42
Fibroblast traction as a mechanism for collagen morphogenesis. Nature (1981) 4.16
Completion of the porcine epidemic diarrhoea coronavirus (PEDV) genome sequence. Virus Genes (2001) 4.10
Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes. Nat Biotechnol (1998) 3.28
Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Exp Neurol (2003) 3.09
Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits. Proc Natl Acad Sci U S A (2007) 3.07
Lineage-independent determination of cell type in the embryonic mouse retina. Neuron (1990) 2.83
Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer. Br J Cancer (2009) 2.76
Percutaneous coronary intervention in the current era compared with 1985-1986: the National Heart, Lung, and Blood Institute Registries. Circulation (2000) 2.65
Expression of the Na-K-2Cl cotransporter is developmentally regulated in postnatal rat brains: a possible mechanism underlying GABA's excitatory role in immature brain. J Neurobiol (1997) 2.24
A mutation in the Norrie disease gene (NDP) associated with X-linked familial exudative vitreoretinopathy. Nat Genet (1993) 2.23
Adeno-associated virus vectors serotyped with AAV8 capsid are more efficient than AAV-1 or -2 serotypes for widespread gene delivery to the neonatal mouse brain. Neuroscience (2006) 2.19
Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes. Nat Biotechnol (1999) 2.18
"Global" cell replacement is feasible via neural stem cell transplantation: evidence from the dysmyelinated shiverer mouse brain. Proc Natl Acad Sci U S A (1999) 2.16
Establishment and characterization of multipotent neural cell lines using retrovirus vector-mediated oncogene transfer. J Neurobiol (1990) 2.15
Herpes simplex virus type 1 DNA amplified as bacterial artificial chromosome in Escherichia coli: rescue of replication-competent virus progeny and packaging of amplicon vectors. Hum Gene Ther (1998) 2.13
Folylpolyglutamyl synthetase gene transfer and glioma antifolate sensitivity in culture and in vivo. J Natl Cancer Inst (1999) 2.10
Current spectrum of cardiogenic shock and effect of early revascularization on mortality. Results of an International Registry. SHOCK Registry Investigators. Circulation (1995) 2.07
Low molecular weight intracellular iron transport compounds. Blood (1977) 2.02
Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells. J Neurosci (1999) 2.02
A defective HSV-1 vector expresses Escherichia coli beta-galactosidase in cultured peripheral neurons. Science (1988) 2.02
Defect of cell-mediated immunity in patients with iron-deficiency anaemia. Lancet (1972) 2.01
A system for data processing in haematology. J Clin Pathol (1974) 1.95
Positron-emission tomography of vector-mediated gene expression in gene therapy for gliomas. Lancet (2001) 1.94
Localization of human monoamine oxidase-A gene to Xp11.23-11.4 by in situ hybridization: implications for Norrie disease. Genomics (1989) 1.93
FGF-2 regulation of neurogenesis in adult hippocampus after brain injury. Proc Natl Acad Sci U S A (2001) 1.90
Mutant torsinA, responsible for early-onset torsion dystonia, forms membrane inclusions in cultured neural cells. Hum Mol Genet (2000) 1.90
Helper virus-free transfer of herpes simplex virus type 1 plasmid vectors into neural cells. J Virol (1996) 1.89
Self-contained, tetracycline-regulated retroviral vector system for gene delivery to mammalian cells. J Virol (1996) 1.82
Trial of strategy for reducing the use of laboratory tests. Br Med J (Clin Res Ed) (1986) 1.82
Retrograde axonal transport of herpes simplex virus: evidence for a single mechanism and a role for tegument. Proc Natl Acad Sci U S A (2000) 1.81
Precision of automatic measurements of pigmented skin lesion parameters with a MelaFind(TM) multispectral digital dermoscope. Melanoma Res (2000) 1.78
Identification of a highly polymorphic microsatellite VNTR within the argininosuccinate synthetase locus: exclusion of the dystonia gene on 9q32-34 as the cause of dopa-responsive dystonia in a large kindred. Am J Hum Genet (1991) 1.77
Structural features of human monoamine oxidase A elucidated from cDNA and peptide sequences. J Neurochem (1988) 1.77
Quality assurance in general practice: the state of the art in Europe. Fam Pract (1994) 1.75
The characteristics of ferritin from human tissues, serum and blood cells. Clin Sci Mol Med (1975) 1.75
Gene transfer to the nigrostriatal system by hybrid herpes simplex virus/adeno-associated virus amplicon vectors. Hum Gene Ther (1999) 1.69
Temperature-sensitive divisionless mutant of Bacillus subtilis defective in the initiation of septation. J Bacteriol (1973) 1.66
Immediate-early RNA 2.9 and early RNA 2.6 of bovine herpesvirus 1 are 3' coterminal and encode a putative zinc finger transactivator protein. J Virol (1992) 1.66
T-DNA integration patterns in co-transformed plant cells suggest that T-DNA repeats originate from co-integration of separate T-DNAs. Plant J (1997) 1.64
Iron metabolism, sickle cell disease, and response to cyanate. Blood (1975) 1.60
Experimental observation of the improvement in MTF from backthinning a CMOS direct electron detector. Ultramicroscopy (2009) 1.60
Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies. J Natl Cancer Inst (1998) 1.60
FMS mutations in myelodysplastic, leukemic, and normal subjects. Proc Natl Acad Sci U S A (1990) 1.58
Serum ferritin in acute leukaemia at presentation and during remission. Br Med J (1975) 1.57
Human monoamine oxidase A gene determines levels of enzyme activity. Am J Hum Genet (1991) 1.56
The measurement of reticuloendothelial iron release using iron-dextran. Br J Haematol (1971) 1.53
Immunocytochemical demonstration of monoamine oxidase B in brain astrocytes and serotonergic neurons. Proc Natl Acad Sci U S A (1982) 1.53
Roles of age, length of service and job in work-related injury: a prospective study of 446 120 person-years in railway workers. Occup Environ Med (2009) 1.50
Respiratory symptoms, ventilatory impairment, and bronchial reactivity in oil mist-exposed automobile workers. Am J Ind Med (1995) 1.50
Ferritin synthesis in normal and leukaemic leukocytes. Nature (1974) 1.48
Neuroprotection through delivery of glial cell line-derived neurotrophic factor by neural stem cells in a mouse model of Parkinson's disease. J Neurosci (2001) 1.48
Establishment and properties of a growth factor-dependent, perpetual neural stem cell line from the human CNS. Exp Neurol (2000) 1.46
Characterization of F107 fimbriae of Escherichia coli 107/86, which causes edema disease in pigs, and nucleotide sequence of the F107 major fimbrial subunit gene, fedA. Infect Immun (1992) 1.45
Improved helper virus-free packaging system for HSV amplicon vectors using an ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome. Mol Ther (2001) 1.45
Neural precursor cells for delivery of replication-conditional HSV-1 vectors to intracerebral gliomas. Mol Ther (2000) 1.45
Respiratory symptoms and bronchial responsiveness in lifeguards exposed to nitrogen trichloride in indoor swimming pools. Occup Environ Med (1998) 1.44
A second isolate of HTLV-II associated with atypical hairy-cell leukemia. N Engl J Med (1986) 1.44
Local protective effects of nerve growth factor-secreting fibroblasts against excitotoxic lesions in the rat striatum. J Neurosurg (1993) 1.44
Functional coexpression of HSV-1 thymidine kinase and green fluorescent protein: implications for noninvasive imaging of transgene expression. Neoplasia (1999) 1.44
Single-step conversion of cells to retrovirus vector producers with herpes simplex virus-Epstein-Barr virus hybrid amplicons. J Virol (1999) 1.43
Replacing 99Tcm-DMSA for renal imaging? Nucl Med Commun (1992) 1.43
Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression. Science (1988) 1.42
Major bleeding complications after cardiopulmonary resuscitation: impact of thrombolytic treatment. J Intern Med (2003) 1.42
The DNA sequences of T-DNA junctions suggest that complex T-DNA loci are formed by a recombination process resembling T-DNA integration. Plant J (1999) 1.41
A rapid method for the detection of ferritin in serum. J Clin Pathol (1971) 1.41
Parkin deletions in a family with adult-onset, tremor-dominant parkinsonism: expanding the phenotype. Ann Neurol (2000) 1.40
RAS and FMS mutations following cytotoxic therapy for childhood acute lymphoblastic leukaemia. Leukemia (1995) 1.39
Long-term outcomes in patients with schizophrenia treated with risperidone long-acting injection or oral antipsychotics in Spain: results from the electronic Schizophrenia Treatment Adherence Registry (e-STAR). Eur Psychiatry (2009) 1.38
Cerebroventricular infusion of pentosan polysulphate in human variant Creutzfeldt-Jakob disease. J Infect (2005) 1.38
HMPAO SPET and FDG PET in Alzheimer's disease and vascular dementia: comparison of perfusion and metabolic pattern. Eur J Nucl Med (1994) 1.38
Ferritinaemia in leukaemia and Hodgkin's disease. Br J Cancer (1973) 1.37
Properties of human tissue isoferritins. Biochem J (1978) 1.37
Evolutionary divergence of genes for ornithine and aspartate carbamoyl-transferases--complete sequence and mode of regulation of the Escherichia coli argF gene; comparison of argF with argI and pyrB. Nucleic Acids Res (1984) 1.37
Localization of the gene for familial dysautonomia on chromosome 9 and definition of DNA markers for genetic diagnosis. Nat Genet (1993) 1.36
Myelodysplastic syndromes: pathogenesis, functional abnormalities, and clinical implications. J Clin Pathol (1985) 1.36
Haemoglobin estimation: a comparison of different techniques. Br Med J (1966) 1.35
Ultrasound enhancement of liposome-mediated cell transfection is caused by cavitation effects. Ultrasound Med Biol (2000) 1.33
Ferritin in normal erythrocytes, lymphocytes, polymorphs, and monocytes. Br J Haematol (1974) 1.32
Structural gene for beta-nerve growth factor not defective in familial dysautonomia. Proc Natl Acad Sci U S A (1984) 1.32
Lung cancer risk in hard-metal workers. Am J Epidemiol (1998) 1.31
Sequence analysis of the porcine epidemic diarrhea virus genome between the nucleocapsid and spike protein genes reveals a polymorphic ORF. Virology (1994) 1.31
Segregation of human neural stem cells in the developing primate forebrain. Science (2001) 1.29