Published in Structure on December 15, 1997
Ca(2+)-regulated structural changes in troponin. Proc Natl Acad Sci U S A (2005) 2.56
Common EF-hand motifs in cholinesterases and neuroligins suggest a role for Ca2+ binding in cell surface associations. Protein Sci (2000) 1.79
Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution. Proc Natl Acad Sci U S A (1998) 1.31
Differential effects of a green tea-derived polyphenol (-)-epigallocatechin-3-gallate on the acidosis-induced decrease in the Ca(2+) sensitivity of cardiac and skeletal muscle. Pflugers Arch (2008) 1.12
Solution structure of human cardiac troponin C in complex with the green tea polyphenol, (-)-epigallocatechin 3-gallate. J Biol Chem (2009) 1.08
Bepridil opens the regulatory N-terminal lobe of cardiac troponin C. Proc Natl Acad Sci U S A (2000) 1.05
Interaction of cardiac troponin with cardiotonic drugs: a structural perspective. Biochem Biophys Res Commun (2007) 1.01
Cooperative [Ca²+]-dependent regulation of the rate of myosin binding to actin: solution data and the tropomyosin chain model. Biophys J (2011) 0.98
Troponin regulatory function and dynamics revealed by H/D exchange-mass spectrometry. J Biol Chem (2009) 0.92
Mass spectrometry-based carboxyl footprinting of proteins: method evaluation. Int J Mass Spectrom (2012) 0.91
Structure and function of cardiac troponin C (TNNC1): Implications for heart failure, cardiomyopathies, and troponin modulating drugs. Gene (2015) 0.88
Proximity relationships between residue 117 of rabbit skeletal troponin-I and residues in troponin-C and actin. Biophys J (2001) 0.87
Correlating calcium binding, Förster resonance energy transfer, and conformational change in the biosensor TN-XXL. Biophys J (2012) 0.87
A model of troponin-I in complex with troponin-C using hybrid experimental data: the inhibitory region is a beta-hairpin. Protein Sci (2000) 0.85
Mutations in the N- and D-helices of the N-domain of troponin C affect the C-domain and regulatory function. Biophys J (1999) 0.83
Effect of metal ion substitutions in anticoagulation factor I from the venom of Agkistrodon acutus on the binding of activated coagulation factor X and on structural stability. J Biol Inorg Chem (2009) 0.80
Electric charge balance mechanism of extended soluble proteins. Protein Sci (2004) 0.80
HD exchange and PLIMSTEX determine the affinities and order of binding of Ca2+ with troponin C. Biochemistry (2011) 0.79
Calcium induced regulation of skeletal troponin--computational insights from molecular dynamics simulations. PLoS One (2013) 0.79
The calcium-saturated cTnI/cTnC complex: structure of the inhibitory region of cTnI. Biophys J (2003) 0.78
Measurement of calcium dissociation rates from troponin C in rigor skeletal myofibrils. Front Physiol (2011) 0.77
Binding properties of the calcium-activated F2 isoform of Lethocerus troponin C. Biochemistry (2011) 0.76
Cardiac Troponin and Tropomyosin: Structural and Cellular Perspectives to Unveil the Hypertrophic Cardiomyopathy Phenotype. Front Physiol (2016) 0.76
Fluorescent Protein-Based Ca2+ Sensor Reveals Global, Divalent Cation-Dependent Conformational Changes in Cardiac Troponin C. PLoS One (2016) 0.76
Structural preference for changes in the direction of the Ca2+-induced transition: a study of the regulatory domain of skeletal troponin-C. Biophys J (2003) 0.75
Structures of the troponin core domain containing the cardiomyopathy-causing mutants studied by small-angle X-ray scattering. Biophys Physicobiol (2015) 0.75
Molecular Basis of S100A1 Activation at Saturating and Subsaturating Calcium Concentrations. Biophys J (2016) 0.75
Streptococcal M protein: alpha-helical coiled-coil structure and arrangement on the cell surface. Proc Natl Acad Sci U S A (1981) 5.56
The crystal structure of uncomplexed actin in the ADP state. Science (2001) 5.27
Use of hospital services by homeless families in an inner London health district. BMJ (1989) 4.71
Randomised placebo-controlled trial of ritonavir in advanced HIV-1 disease. The Advanced HIV Disease Ritonavir Study Group. Lancet (1998) 4.54
American Cancer Society guidelines for the early detection of cancer: update of early detection guidelines for prostate, colorectal, and endometrial cancers. Also: update 2001--testing for early lung cancer detection. CA Cancer J Clin (2001) 4.41
Three conformational states of scallop myosin S1. Proc Natl Acad Sci U S A (2000) 3.06
Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head. Cell (1999) 2.99
Structure of the regulatory domain of scallop myosin at 2.8 A resolution. Nature (1994) 2.78
A tropomyosin-like protein from human platelets. J Mol Biol (1972) 2.65
Tropomyosin crystal structure and muscle regulation. J Mol Biol (1986) 2.65
Interim report on pandemic H1N1 influenza virus infections in South Africa, April to October 2009: epidemiology and factors associated with fatal cases. Euro Surveill (2009) 2.47
Cooperative effects of INK4a and ras in melanoma susceptibility in vivo. Genes Dev (1997) 2.47
Structure of the regulatory domain of scallop myosin at 2 A resolution: implications for regulation. Structure (1996) 2.45
Paramyosin and the filaments of molluscan "catch" muscles. II. Native filaments: isolation and characterization. J Mol Biol (1971) 2.42
Heptad breaks in alpha-helical coiled coils: stutters and stammers. Proteins (1996) 2.30
Sertraline in children and adolescents with obsessive-compulsive disorder: a multicenter randomized controlled trial. JAMA (1998) 2.20
Crystal structure and molecular interactions of tropomyosin. Nature (1979) 2.16
Deciphering the design of the tropomyosin molecule. Proc Natl Acad Sci U S A (2001) 2.14
Laparoscopic live donor nephrectomy: the recipient. Transplantation (2000) 2.11
Leishmaniasis acquired in Belgium. Lancet (1991) 1.93
Expression profiling of renal epithelial neoplasms: a method for tumor classification and discovery of diagnostic molecular markers. Am J Pathol (2001) 1.89
X-ray diffraction from microtubules. J Mol Biol (1971) 1.84
Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor. Proc Natl Acad Sci U S A (2002) 1.81
Tumor progression in four mammary epithelial cell lines derived from the same patient. Cancer Res (1990) 1.80
Tropomyosin: crystal structure, polymorphism and molecular interactions. J Mol Biol (1969) 1.79
A general method for the introduction of enzymes, by means of immunoglobulin-coated liposomes, into lysosomes of deficient cells. Proc Natl Acad Sci U S A (1975) 1.76
Tropomyosin paracrystals formed by divalent cations. Science (1966) 1.73
The Test for Severe Impairment: an instrument for the assessment of patients with severe cognitive dysfunction. J Am Geriatr Soc (1992) 1.72
Incidence and natural history of phrenic neuropathy occurring during open heart surgery. Chest (1993) 1.68
The crystal structure of modified bovine fibrinogen. Proc Natl Acad Sci U S A (2000) 1.67
Chiari III malformation: imaging features. AJNR Am J Neuroradiol (1992) 1.65
Electron microscopy of thin filaments decorated with a Ca2+-regulated myosin. J Mol Biol (1980) 1.64
Cooperative binding to the Ca2+-specific sites of troponin C in regulated actin and actomyosin. J Biol Chem (1983) 1.61
Underestimation of chronic hepatitis B virus infection in the United States of America. J Viral Hepat (2008) 1.58
Ritonavir and saquinavir combination therapy for the treatment of HIV infection. AIDS (1999) 1.58
Association of an HLA-DQ allele with clinical tuberculosis. JAMA (1998) 1.58
Microtubule structure at 18 A resolution. J Mol Biol (1987) 1.56
Social and community resources and long-term recovery from treated and untreated alcoholism. J Stud Alcohol (1997) 1.55
Utilization of cereal and fruit fibres in low fat dry fermented sausages. Meat Sci (2002) 1.55
A model for fibrinogen: domains and sequence. Science (1985) 1.53
A 29 residue region of the sarcomeric myosin rod is necessary for filament formation. J Mol Biol (1997) 1.52
Cross-bridge arrangements in Limulus muscle. J Mol Biol (1974) 1.48
Troponin and its interactions with tropomyosin. An electron microscope study. J Mol Biol (1982) 1.48
A model of Ca(2+)-free calmodulin binding to unconventional myosins reveals how calmodulin acts as a regulatory switch. Structure (1996) 1.48
Paramyosin and the filaments of molluscan "catch" muscles. I. Paramyosin: structure and assembly. J Mol Biol (1971) 1.47
Structure of co-crystals of tropomyosin and troponin. Nature (1987) 1.47
Disabled-2 inactivation is an early step in ovarian tumorigenicity. Oncogene (1999) 1.46
Pitch diversity in alpha-helical coiled coils. Proteins (1993) 1.44
Sexual and physical abuse histories and psychiatric symptoms among male psychiatric outpatients. Am J Psychiatry (1990) 1.43
What transplantation can teach us about health care reform. The Ethics and Social Impact Committee. N Engl J Med (1994) 1.40
DNA ploidy of ameloblastoma and ameloblastic carcinoma of the jaws. Analysis by image and flow cytometry. Arch Pathol Lab Med (1993) 1.39
Determinants of prolonged length of hospital stay after coronary bypass surgery. Circulation (1989) 1.39
Factors associated with long-term institutionalization of older people with dementia: data from the Canadian Study of Health and Aging. J Gerontol A Biol Sci Med Sci (2001) 1.35
Motions of tropomyosin. Crystal as metaphor. Biophys J (1980) 1.35
Isolation of mouse stromal cells associated with a human tumor using differential diphtheria toxin sensitivity. Am J Pathol (1999) 1.33
Structure and modulation of neural cell adhesion molecules in early and late embryogenesis. Cold Spring Harb Symp Quant Biol (1983) 1.32
Domains, motions and regulation in the myosin head. J Muscle Res Cell Motil (1988) 1.31
A high-resolution radiation hybrid map of the human genome draft sequence. Science (2001) 1.30
Granulomatous mastitis. A review of 5 cases. S Afr Med J (1977) 1.29
A model from electron microscopy for the molecular structure of fibrinogen and fibrin. Nature (1981) 1.29
Extracellular regulated kinase (ERK) interaction with actin and the calponin homology (CH) domain of actin-binding proteins. Biochem J (1999) 1.29
Recognition of single-stranded DNA by nuclease P1: high resolution crystal structures of complexes with substrate analogs. Proteins (1998) 1.28
Aortic dissection: diagnosis and follow-up with helical CT. Radiographics (1999) 1.28
The recognition, assessment and management of dementing disorders: conclusions from the Canadian Consensus Conference on Dementia. Can J Neurol Sci (2001) 1.27
Differential expression of active mitogen-activated protein kinase in cutaneous endothelial neoplasms: implications for biologic behavior and response to therapy. J Am Acad Dermatol (2001) 1.25
Tumor angiogenesis as a prognostic factor in oral cavity tumors. Am J Surg (1994) 1.24
Diversity of cross-bridge configurations in invertebrate muscles. Nature (1975) 1.23
Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis. Carcinogenesis (2001) 1.23
Immunohistochemical localization of rat angiotensin II AT1 receptor. Am J Physiol (1993) 1.23
Discriminatory immunohistochemical staining of urothelial carcinoma in situ and non-neoplastic urothelium: an analysis of cytokeratin 20, p53, and CD44 antigens. Am J Surg Pathol (2001) 1.20
Actin filaments in muscle: pattern of myosin and tropomyosin/troponin attachments. J Mol Biol (1978) 1.20
Inhibition of degranulation and interleukin-6 production in mast cells derived from mice deficient in protein kinase Cbeta. Blood (2000) 1.19
HSV shedding. Antiviral Res (2004) 1.18
Pediatric total parenteral nutrition. Liver histopathology. Arch Pathol Lab Med (1981) 1.18
Analysis of the three-alpha-helix motif in the spectrin superfamily of proteins. Biophys J (1992) 1.18
Proteolytic fragments of troponin C. Localization of high and low affinity Ca2+ binding sites and interactions with troponin I and troponin T. J Biol Chem (1978) 1.18
Restoration of positioning control following Disabled-2 expression in ovarian and breast tumor cells. Oncogene (2000) 1.18
Effects of various doses of estradiol on chlamydial genital infection in ovariectomized guinea pigs. Sex Transm Dis (1985) 1.17
Bioethicists' statement on the U.S. Supreme Court's Cruzan decision. N Engl J Med (1990) 1.15
Neuroendocrine tumors of the thymus: a clinicopathological and prognostic study. Ann Thorac Surg (2001) 1.15
Paramyosin inhibits complement C1. J Immunol (1992) 1.14
Should the indications for laparascopic live donor nephrectomy of the right kidney be the same as for the open procedure? Anomalous left renal vasculature is not a contraindiction to laparoscopic left donor nephrectomy. Transplantation (2001) 1.14
Dual effect of ATP in the activation mechanism of brain Ca(2+)/calmodulin-dependent protein kinase II by Ca(2+)/calmodulin. Biochemistry (2001) 1.14
Blocking the Ca2+-induced conformational transitions in calmodulin with disulfide bonds. J Biol Chem (1996) 1.14
Relationship of cytokeratin 20 and CD44 protein expression with WHO/ISUP grade in pTa and pT1 papillary urothelial neoplasia. Mod Pathol (2000) 1.14
Segments from vertebrate smooth muscle myosin rods. J Mol Biol (1971) 1.13
The crystal structure of endoglucanase CelA, a family 8 glycosyl hydrolase from Clostridium thermocellum. Structure (1996) 1.13
Structure of tropomyosin at 9 angstroms resolution. J Mol Biol (1992) 1.13
Crystalline states of a modified fibrinogen. J Mol Biol (1977) 1.12
Similarity in Ca2+-induced changes between troponic-C and protein activator of 3':5'-cyclic nucleotide phosphodiesterase and their tryptic fragments. Biochim Biophys Acta (1977) 1.12
From the National Institutes of Health. Summary of a workshop on cytomegalovirus infections during organ transplantation. J Infect Dis (1979) 1.11
A new myosin fragment: visualization of the regulatory domain. Nature (1984) 1.11
Surveillance of transmitted HIV-1 drug resistance in Gauteng and KwaZulu-Natal Provinces, South Africa, 2005-2009. Clin Infect Dis (2012) 1.11
Spikes and fimbriae: alpha-helical proteins form surface projections on microorganisms. Proc Natl Acad Sci U S A (1981) 1.10
Tropomyosin crystal dynamics. Cold Spring Harb Symp Quant Biol (1972) 1.10
Proteolytic degradation of myosin and the meromyosins by a water-insoluble polyanionic derivative of trypsin: properties of a helical subunit isolated from heavy meromyosin. J Mol Biol (1967) 1.09