Published in Annu Rev Genet on January 01, 1997
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. Genes Dev (2000) 5.80
TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm. Genes Dev (2001) 5.41
Enumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol (2002) 4.77
E1A signaling to p53 involves the p19(ARF) tumor suppressor. Genes Dev (1998) 4.60
DNA binding by Kaposi's sarcoma-associated herpesvirus lytic switch protein is necessary for transcriptional activation of two viral delayed early promoters. J Virol (2001) 2.32
TRRAP-dependent and TRRAP-independent transcriptional activation by Myc family oncoproteins. Mol Cell Biol (2002) 1.80
ICP22 and the UL13 protein kinase are both required for herpes simplex virus-induced modification of the large subunit of RNA polymerase II. J Virol (1999) 1.73
Regulatable gene expression systems for gene therapy applications: progress and future challenges. Mol Ther (2005) 1.61
Intrinsic structural disorder in adenovirus E1A: a viral molecular hub linking multiple diverse processes. J Virol (2008) 1.53
Acetylation-deacetylation of the transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) regulates its transcriptional activity and nucleocytoplasmic localization. J Biol Chem (2010) 1.45
p21 and retinoblastoma protein control the absence of DNA replication in terminally differentiated muscle cells. J Cell Biol (2000) 1.44
p53 status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infection. J Virol (1998) 1.44
Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein. J Virol (2000) 1.43
Regulation of beta -catenin transformation by the p300 transcriptional coactivator. Proc Natl Acad Sci U S A (2000) 1.41
Adenovirus E1B 55-kilodalton oncoprotein inhibits p53 acetylation by PCAF. Mol Cell Biol (2000) 1.25
Genomic and bioinformatics analysis of HAdV-4, a human adenovirus causing acute respiratory disease: implications for gene therapy and vaccine vector development. J Virol (2005) 1.24
Strategic attack on host cell gene expression during adenovirus infection. J Virol (2003) 1.21
Inhibition of TNF receptor 1 internalization by adenovirus 14.7K as a novel immune escape mechanism. J Clin Invest (2006) 1.20
An activation domain in the C-terminal subunit of HCF-1 is important for transactivation by VP16 and LZIP. Proc Natl Acad Sci U S A (2002) 1.15
The human cytomegalovirus UL82 gene product (pp71) accelerates progression through the G1 phase of the cell cycle. J Virol (2003) 1.14
Genetic identification of adenovirus type 5 genes that influence viral spread. J Virol (2006) 1.14
Specificity of cyclin E-Cdk2, TFIIB, and E1A interactions with a common domain of the p300 coactivator. Mol Cell Biol (1999) 1.13
Advances in Gene Delivery Systems. Pharmaceut Med (2011) 1.09
Structure and functions of powerful transactivators: VP16, MyoD and FoxA. Int J Dev Biol (2010) 1.09
Adenovirus E1B 55-kilodalton oncoprotein binds to Daxx and eliminates enhancement of p53-dependent transcription by Daxx. J Virol (2003) 1.08
Adenovirus type 5 exerts genome-wide control over cellular programs governing proliferation, quiescence, and survival. Genome Biol (2007) 1.07
General and specific alterations in programming of global viral gene expression during infection by VP16 activation-deficient mutants of herpes simplex virus type 1. J Virol (2002) 1.06
BRCA1 interaction with RNA polymerase II reveals a role for hRPB2 and hRPB10alpha in activated transcription. Proc Natl Acad Sci U S A (2000) 1.06
Adenovirus E1B55K region is required to enhance cyclin E expression for efficient viral DNA replication. J Virol (2008) 1.05
The Autographa californica multiple nucleopolyhedrovirus ie0-ie1 gene complex is essential for wild-type virus replication, but either IE0 or IE1 can support virus growth. J Virol (2005) 1.04
E1A and E1B proteins inhibit inflammation induced by adenovirus. Proc Natl Acad Sci U S A (2004) 1.03
Quantification of high-capacity helper-dependent adenoviral vector genomes in vitro and in vivo, using quantitative TaqMan real-time polymerase chain reaction. Hum Gene Ther (2006) 1.02
Adenoviral vector-based strategies for cancer therapy. Curr Drug ther (2009) 1.02
ONYX-015: mechanisms of action and clinical potential of a replication-selective adenovirus. Br J Cancer (2002) 1.02
Roles of Arabidopsis cyclin-dependent kinase C complexes in cauliflower mosaic virus infection, plant growth, and development. Plant Cell (2007) 1.01
Adenovirus protein VII functions throughout early phase and interacts with cellular proteins SET and pp32. J Virol (2005) 1.01
Specific TATAA and bZIP requirements suggest that HTLV-I Tax has transcriptional activity subsequent to the assembly of an initiation complex. Retrovirology (2004) 0.98
Adenovirus protein VII condenses DNA, represses transcription, and associates with transcriptional activator E1A. J Virol (2004) 0.98
Promyelocytic leukemia-nuclear body proteins: herpesvirus enemies, accomplices, or both? Future Virol (2008) 0.98
Conditionally replicating adenoviruses for cancer treatment. Curr Cancer Drug Targets (2007) 0.98
The highly conserved basic domain I of baculovirus IE1 is required for hr enhancer DNA binding and hr-dependent transactivation. J Virol (2003) 0.95
Oncolytic adenovirus: preclinical and clinical studies in patients with human malignant gliomas. Curr Gene Ther (2009) 0.94
Activation of adenoviral gene expression by protein IX is not required for efficient virus replication. J Virol (2004) 0.93
A novel Arabidopsis acetyltransferase interacts with the geminivirus movement protein NSP. Plant Cell (2003) 0.92
Regulatable gene expression systems for gene therapy. Curr Gene Ther (2006) 0.92
Activation of the Notch-regulated transcription factor CBF1/RBP-Jkappa through the 13SE1A oncoprotein. Genes Dev (2001) 0.88
The geminivirus nuclear shuttle protein NSP inhibits the activity of AtNSI, a vascular-expressed Arabidopsis acetyltransferase regulated with the sink-to-source transition. Plant Physiol (2006) 0.88
Heterogeneous nuclear ribonucleoprotein R enhances transcription from the naturally configured c-fos promoter in vitro. J Biol Chem (2009) 0.87
Identification of an adeno-associated virus Rep protein binding site in the adenovirus E2a promoter. J Virol (2005) 0.86
Identification of a novel activation domain in the Notch-responsive transcription factor CSL. Nucleic Acids Res (2001) 0.86
The adenovirus e3 promoter is sensitive to activation signals in human T cells. J Virol (2003) 0.85
Relationship between adenovirus DNA replication proteins and nucleolar proteins B23.1 and B23.2. J Gen Virol (2007) 0.83
A new coactivator function for Zac1's C2H2 zinc finger DNA-binding domain in selectively controlling PCAF activity. Mol Cell Biol (2008) 0.82
Accurate single-day titration of adenovirus vectors based on equivalence of protein VII nuclear dots and infectious particles. J Virol Methods (2009) 0.81
Effect on polyomavirus T-antigen function of mutations in a conserved leucine-rich segment of the DnaJ domain. J Virol (2001) 0.80
Retroviral vectors for establishing tetracycline-regulated gene expression in an otherwise recalcitrant cell line. BMC Mol Biol (2002) 0.80
Probable presence of an ubiquitous cryptic mitochondrial gene on the antisense strand of the cytochrome oxidase I gene. Biol Direct (2011) 0.79
Dissection of the C-terminal region of E1A redefines the roles of CtBP and other cellular targets in oncogenic transformation. J Virol (2013) 0.78
A tetracycline repressor-based mammalian two-hybrid system to detect protein-protein interactions in vivo. Anal Biochem (2008) 0.78
Therapeutic efficacy of an oncolytic adenovirus containing RGD ligand in minor capsid protein IX and Fiber, Δ24DoubleRGD, in an ovarian cancer model. J Mol Biochem (2012) 0.76
Infection of murine keratinocytes with herpes simplex virus type 1 induces the expression of interleukin-10, but not interleukin-1 alpha or tumour necrosis factor-alpha. Immunology (2001) 0.76
Rapamycin-induced inhibition of HTLV-I LTR activity is rescued by c-Myb. Retrovirology (2007) 0.76
Virotherapy: cancer gene therapy at last? F1000Res (2016) 0.75
Fine-tuned SRF activity controls asymmetrical neuronal outgrowth: implications for cortical migration, neural tissue lamination and circuit assembly. Sci Rep (2015) 0.75
Competitive Inhibition of Lysine Acetyltransferase 2B by a Small Motif of the Adenoviral Oncoprotein E1A. J Biol Chem (2016) 0.75
Efficient transformation of primary human mesenchymal stromal cells by adenovirus early region 1 oncogenes. J Virol (2016) 0.75
Deoxycholic Acid Could Induce Apoptosis and Trigger Gastric Carcinogenesis on Gastric Epithelial Cells by Quantitative Proteomic Analysis. Gastroenterol Res Pract (2016) 0.75
An adenovirus type 5 early gene function regulates expression of other early viral genes. Proc Natl Acad Sci U S A (1979) 13.21
The sequence 5'-AAUAAA-3'forms parts of the recognition site for polyadenylation of late SV40 mRNAs. Cell (1981) 12.26
Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells. Cell (1979) 10.95
Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein. Cell (1991) 8.31
The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element. Cell (1983) 8.19
Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression. J Virol (1989) 6.69
Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors. J Virol (1996) 6.22
Adenovirus VAI RNA is required for efficient translation of viral mRNAs at late times after infection. Cell (1982) 5.80
Transcriptional control regions of the adenovirus VAI RNA gene. Cell (1980) 5.64
Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. EMBO J (1998) 4.98
Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2 alpha kinase. Cell (1986) 4.72
A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication. J Virol (1987) 4.57
Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff. J Virol (1985) 4.35
Cellular gene expression altered by human cytomegalovirus: global monitoring with oligonucleotide arrays. Proc Natl Acad Sci U S A (1998) 4.33
YY1 is an initiator sequence-binding protein that directs and activates transcription in vitro. Nature (1991) 4.30
Isolation of deletion and substitution mutants of adenovirus type 5. Cell (1978) 4.29
New region of the simian virus 40 genome required for efficient viral transformation. Proc Natl Acad Sci U S A (1978) 4.24
Human cytomegalovirus IE1 and IE2 proteins block apoptosis. J Virol (1995) 4.22
Wild-type p53 binds to the TATA-binding protein and represses transcription. Proc Natl Acad Sci U S A (1992) 4.06
Adenovirus virus-associated RNA and translation control. J Virol (1991) 3.77
A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motif. Cell (1988) 3.44
A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs. Genes Dev (1990) 3.43
Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells. J Virol (1984) 3.38
A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene. Proc Natl Acad Sci U S A (1987) 3.38
The adenovirus E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAs. Mol Cell Biol (1986) 3.36
Definition of the boundaries of the origin of DNA replication in simian virus 40. Nucleic Acids Res (1978) 3.32
Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAs. Proc Natl Acad Sci U S A (1997) 3.25
Altered cellular mRNA levels in human cytomegalovirus-infected fibroblasts: viral block to the accumulation of antiviral mRNAs. J Virol (2001) 3.22
A subset of viral transcripts packaged within human cytomegalovirus particles. Science (2000) 3.19
Human cytomegalovirus tegument protein pp71 (ppUL82) enhances the infectivity of viral DNA and accelerates the infectious cycle. J Virol (1997) 3.16
Functional analysis of adenovirus-5 host-range deletion mutants defective for transformation of rat embryo cells. Cold Spring Harb Symp Quant Biol (1980) 3.15
Adenovirus tripartite leader sequence enhances translation of mRNAs late after infection. Proc Natl Acad Sci U S A (1984) 3.11
Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infection. Proc Natl Acad Sci U S A (1985) 3.09
A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs. Mol Cell Biol (1991) 3.05
Proteins associated with purified human cytomegalovirus particles. J Virol (1996) 3.01
Conversion of the lac repressor into an allosterically regulated transcriptional activator for mammalian cells. Mol Cell Biol (1990) 3.00
Impact of virus infection on host cell protein synthesis. Annu Rev Biochem (1987) 2.98
The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location. Mol Cell Biol (1994) 2.94
Interaction between transcription factors Sp1 and YY1. Nature (1993) 2.87
Transcriptional control regions: nucleotide sequence requirements for initiation by RNA polymerase II and III. Curr Top Microbiol Immunol (1981) 2.85
Adenovirus VAI RNA facilitates the initiation of translation in virus-infected cells. Cell (1984) 2.76
TATA-binding protein-independent initiation: YY1, TFIIB, and RNA polymerase II direct basal transcription on supercoiled template DNA. Cell (1994) 2.68
Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor. Science (1996) 2.56
Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence. EMBO J (1997) 2.44
A uridylate tract mediates efficient heterogeneous nuclear ribonucleoprotein C protein-RNA cross-linking and functionally substitutes for the downstream element of the polyadenylation signal. Mol Cell Biol (1990) 2.43
Human cytomegalovirus infection inhibits cell cycle progression at multiple points, including the transition from G1 to S. J Virol (1996) 2.41
Replication of wild-type and mutant human cytomegalovirus in life-extended human diploid fibroblasts. J Virol (2000) 2.41
Deletion of the gene encoding the adenovirus 5 early region 1b 21,000-molecular-weight polypeptide leads to degradation of viral and host cell DNA. J Virol (1984) 2.39
A chimeric mammalian transactivator based on the lac repressor that is regulated by temperature and isopropyl beta-D-thiogalactopyranoside. Proc Natl Acad Sci U S A (1991) 2.35
Dissection of overlapping functions within the adenovirus type 5 E1A gene. EMBO J (1984) 2.30
Fragments of the simian virus 40 transforming gene facilitate transformation of rat embryo cells. Proc Natl Acad Sci U S A (1982) 2.29
Transcription termination within the E1A gene of adenovirus induced by insertion of the mouse beta-major globin terminator element. Cell (1985) 2.29
Nucleotide sequence analysis of viable deletion mutants lacking segments of the simian virus 40 genome coding for small t antigen. J Virol (1979) 2.28
Adenovirus E1A protein paradigm viral transactivator. Annu Rev Genet (1989) 2.23
Analysis of adenovirus early region 4-encoded polypeptides synthesized in productively infected cells. J Virol (1987) 2.20
Cocrystal structure of YY1 bound to the adeno-associated virus P5 initiator. Proc Natl Acad Sci U S A (1996) 2.16
The human 64-kDa polyadenylylation factor contains a ribonucleoprotein-type RNA binding domain and unusual auxiliary motifs. Proc Natl Acad Sci U S A (1992) 2.15
The adenovirus type 5 E1A enhancer contains two functionally distinct domains: one is specific for E1A and the other modulates all early units in cis. Cell (1986) 2.14
The C proteins of heterogeneous nuclear ribonucleoprotein complexes interact with RNA sequences downstream of polyadenylation cleavage sites. Mol Cell Biol (1988) 2.14
Adenoviral control regions activated by E1A and the cAMP response element bind to the same factor. Proc Natl Acad Sci U S A (1988) 2.14
DNA binding sites for the transcriptional activator/repressor YY1. Nucleic Acids Res (1995) 2.10
Identification of a repeated sequence element required for efficient encapsidation of the adenovirus type 5 chromosome. J Virol (1987) 2.09
Adenovirus type 5 virions can be assembled in vivo in the absence of detectable polypeptide IX. J Virol (1981) 2.07
Functional analysis of point mutations in the AAUAAA motif of the SV40 late polyadenylation signal. Nucleic Acids Res (1989) 1.99
Adenovirus E4orf4 protein binds to protein phosphatase 2A, and the complex down regulates E1A-enhanced junB transcription. J Virol (1993) 1.98
Increased anxiety of mice lacking the serotonin1A receptor. Proc Natl Acad Sci U S A (1998) 1.97
Adeno-associated virus P5 promoter contains an adenovirus E1A-inducible element and a binding site for the major late transcription factor. J Virol (1989) 1.96
The MDM2 oncoprotein binds specifically to RNA through its RING finger domain. Mol Med (1996) 1.94
Human cytomegalovirus UL69 protein is required for efficient accumulation of infected cells in the G1 phase of the cell cycle. Proc Natl Acad Sci U S A (2000) 1.91
Sequence-independent autoregulation of the adenovirus type 5 E1A transcription unit. Mol Cell Biol (1985) 1.90
Human cytomagalovirus IE1 and IE2 proteins are mutagenic and mediate "hit-and-run" oncogenic transformation in cooperation with the adenovirus E1A proteins. Proc Natl Acad Sci U S A (1997) 1.85
A multicomponent complex is required for the AAUAAA-dependent cross-linking of a 64-kilodalton protein to polyadenylation substrates. Mol Cell Biol (1990) 1.84
E1B 55-kilodalton-associated protein: a cellular protein with RNA-binding activity implicated in nucleocytoplasmic transport of adenovirus and cellular mRNAs. J Virol (1998) 1.83
Construction of a viable SV40 variant containing two functional origins of DNA replication. Cell (1978) 1.83
An adenovirus early region 4 gene product is required for induction of the infection-specific form of cellular E2F activity. Genes Dev (1989) 1.82
Human cytomegalovirus UL36 protein is dispensable for viral replication in cultured cells. J Virol (1999) 1.80
Early viral proteins in HeLa cells infected with adenovirus type 5 host range mutants. Virology (1980) 1.79
Characterization of the human cytomegalovirus irs1 and trs1 genes: a second immediate-early transcription unit within irs1 whose product antagonizes transcriptional activation. J Virol (1997) 1.79
Oncogenic potential of the adenovirus E4orf6 protein. Proc Natl Acad Sci U S A (1996) 1.78
A mutation which alters initiation of transcription by RNA polymerase III on the Ad5 chromosome. Cell (1979) 1.75
Adenovirus terminal protein mediates both nuclear matrix association and efficient transcription of adenovirus DNA. Genes Dev (1990) 1.74
Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression. Mol Cell Biol (1995) 1.73
Human cytomegalovirus UL69 protein induces cells to accumulate in G1 phase of the cell cycle. J Virol (1999) 1.72
Adenovirus L1 52- and 55-kilodalton proteins are required for assembly of virions. J Virol (1989) 1.71
Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein. Proc Natl Acad Sci U S A (1994) 1.69
The adenovirus E1B 55 kd protein influences mRNA transport via an intranuclear effect on RNA metabolism. EMBO J (1989) 1.67
Simian virus 40 agnoprotein facilitates normal nuclear location of the major capsid polypeptide and cell-to-cell spread of virus. J Virol (1986) 1.67
Genetic analysis of adenoviruses. Curr Top Microbiol Immunol (1984) 1.66
Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells. J Virol (1996) 1.65
Adenovirus E4orf4 protein reduces phosphorylation of c-Fos and E1A proteins while simultaneously reducing the level of AP-1. J Virol (1992) 1.61
pIRS1 and pTRS1 are present in human cytomegalovirus virions. J Virol (1997) 1.61
Use of a membrane-localized green fluorescent protein allows simultaneous identification of transfected cells and cell cycle analysis by flow cytometry. Cytometry (1997) 1.56
Adenovirus E1A proteins interact with the cellular YY1 transcription factor. J Virol (1995) 1.52
SV40 mutant tsA1499 is heat-sensitive for lytic growth but generates cold-sensitive rat-cell transformants. Cold Spring Harb Symp Quant Biol (1980) 1.52
Adenovirus E1B 55-Mr polypeptide facilitates timely cytoplasmic accumulation of adeno-associated virus mRNAs. J Virol (1988) 1.48
Protection against apoptosis by the vaccinia virus SPI-2 (B13R) gene product. J Virol (1996) 1.48
Integration in vivo into simian virus 40 DNA of a sequence that resembles a certain family of genomic interspersed repeated sequences. Proc Natl Acad Sci U S A (1980) 1.46
Human adenovirus type 9-induced rat mammary tumors. J Virol (1991) 1.43