Published in Neurology on January 01, 1998
Citalopram to Enhance Cognition in HD (CIT-HD) | NCT00271596
Progression of structural neuropathology in preclinical Huntington's disease: a tensor based morphometry study. J Neurol Neurosurg Psychiatry (2005) 2.54
Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage. Hum Mol Genet (2011) 2.34
"Frontal" behaviors before the diagnosis of Huntington's disease and their relationship to markers of disease progression: evidence of early lack of awareness. J Neuropsychiatry Clin Neurosci (2010) 1.76
Mitochondrial structural and functional dynamics in Huntington's disease. Brain Res Rev (2009) 1.37
Brain imaging and cognitive dysfunctions in Huntington's disease. J Psychiatry Neurosci (2006) 1.35
Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease. PLoS One (2012) 1.31
Cerebral cortex structure in prodromal Huntington disease. Neurobiol Dis (2010) 1.17
Magnetic resonance imaging of Huntington's disease: preparing for clinical trials. Neuroscience (2009) 1.14
Exploratory 7-Tesla magnetic resonance spectroscopy in Huntington's disease provides in vivo evidence for impaired energy metabolism. J Neurol (2011) 1.02
R6/2 Huntington's disease mice develop early and progressive abnormal brain metabolism and seizures. J Neurosci (2012) 0.98
Brain metabolite alterations and cognitive dysfunction in early Huntington's disease. Mov Disord (2012) 0.97
Multicenter reliability of diffusion tensor imaging. Brain Connect (2012) 0.97
The differential role of premotor frontal cortex and basal ganglia in motor sequence learning: evidence from focal basal ganglia lesions. Learn Mem (2002) 0.95
Cognitive change in patients with Huntington disease on the Repeatable Battery for the Assessment of Neuropsychological Status. J Clin Exp Neuropsychol (2009) 0.92
Enlarged right superior temporal gyrus in children and adolescents with autism. Brain Res (2010) 0.90
Diffusion Tensor Imaging in Preclinical Huntington's Disease. Brain Imaging Behav (2009) 0.90
Diffusion weighted imaging of prefrontal cortex in prodromal Huntington's disease. Hum Brain Mapp (2013) 0.89
Cortical gyrification in autistic and Asperger disorders: a preliminary magnetic resonance imaging study. J Child Neurol (2010) 0.89
Neural bases of dysphoria in early Huntington's disease. Psychiatry Res (2008) 0.88
Structural brain abnormalities in juvenile myoclonic epilepsy patients: volumetry and voxel-based morphometry. Korean J Radiol (2006) 0.88
Magnetic resonance imaging and magnetic resonance spectroscopy in dementias. J Geriatr Psychiatry Neurol (2001) 0.87
"Pre-symptomatic" Huntington's disease. Handb Clin Neurol (2008) 0.85
Brief report: abnormal association between the thalamus and brain size in Asperger's disorder. J Autism Dev Disord (2007) 0.84
Stable Atlas-based Mapped Prior (STAMP) machine-learning segmentation for multicenter large-scale MRI data. Magn Reson Imaging (2014) 0.84
Dorsolateral prefrontal cortex magnetic resonance imaging measurements and cognitive performance in autism. J Child Neurol (2010) 0.83
Deep white matter in Huntington's disease. PLoS One (2014) 0.83
Prefrontal cortex white matter tracts in prodromal Huntington disease. Hum Brain Mapp (2015) 0.82
Motor-Language Coupling in Huntington's Disease Families. Front Aging Neurosci (2014) 0.80
Spatiotemporal mapping of brain atrophy in mouse models of Huntington's disease using longitudinal in vivo magnetic resonance imaging. Neuroimage (2012) 0.79
EEG low-resolution brain electromagnetic tomography (LORETA) in Huntington's disease. J Neurol (2010) 0.79
Clinical severity of Huntington's disease does not always correlate with neuropathologic stage. Mov Disord (2012) 0.79
Studies on the Q175 Knock-in Model of Huntington's Disease Using Functional Imaging in Awake Mice: Evidence of Olfactory Dysfunction. Front Neurol (2014) 0.78
Corticostriatal Dysfunction in Huntington's Disease: The Basics. Front Hum Neurosci (2016) 0.75
Evidence from the R6/2 Mouse Model of Huntington's Disease for Using Abnormal Brain Metabolism as a Biomarker for Evaluating Therapeutic Approaches for Treatment. Future Neurol (2015) 0.75
Longitudinal diffusion changes in prodromal and early HD: Evidence of white-matter tract deterioration. Hum Brain Mapp (2017) 0.75
Bladder dysfunction in presymptomatic gene carriers and patients with Huntington's disease. J Neurol (2014) 0.75
Progress in Huntington's disease: the search for markers of disease onset and progression. J Neurol (2015) 0.75
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science (2009) 13.45
Racial Differences in Physical and Mental Health: Socio-economic Status, Stress and Discrimination. J Health Psychol (1997) 12.95
A method for making group inferences from functional MRI data using independent component analysis. Hum Brain Mapp (2001) 12.54
Racism as a stressor for African Americans. A biopsychosocial model. Am Psychol (1999) 11.00
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell (1997) 9.57
Detection of Huntington's disease decades before diagnosis: the Predict-HD study. J Neurol Neurosurg Psychiatry (2007) 5.49
Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proc Natl Acad Sci U S A (1997) 4.89
Microsatellite evolution--evidence for directionality and variation in rate between species. Nat Genet (1995) 4.77
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nat Med (2001) 4.22
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science (2001) 4.13
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice. Nat Med (1997) 4.10
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin. Hum Mol Genet (1999) 4.06
Childhood trauma, psychosis and schizophrenia: a literature review with theoretical and clinical implications. Acta Psychiatr Scand (2005) 3.96
Spatial and temporal independent component analysis of functional MRI data containing a pair of task-related waveforms. Hum Brain Mapp (2001) 3.78
Multicentre trials of praziquantel in human schistosomiasis: design and techniques. Bull World Health Organ (1979) 3.59
Diffusion tensor imaging and axonal tracking in the human brainstem. Neuroimage (2001) 3.58
Antigenic relationship of varicella-zoster and herpes simplex. Lancet (1965) 3.33
Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia. J Neurol Neurosurg Psychiatry (1998) 3.26
CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion. Neurology (2012) 3.12
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease. Hum Mol Genet (2000) 3.07
fMRI activation in a visual-perception task: network of areas detected using the general linear model and independent components analysis. Neuroimage (2001) 2.94
Are all wheezing disorders in very young (preschool) children increasing in prevalence? Lancet (2001) 2.90
Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats. Am J Hum Genet (1996) 2.88
Onset and rate of striatal atrophy in preclinical Huntington disease. Neurology (2004) 2.81
Influenza, respiratory syncytial virus, and pneumonia in Glasgow, 1962-5. Br Med J (1967) 2.76
Malignant gastrointestinal stromal tumors of the small intestine: a review of 50 cases from a prospective database. Ann Surg Oncol (2001) 2.70
A huntingtin-associated protein enriched in brain with implications for pathology. Nature (1995) 2.67
Prevalence of psychopathology among children and adolescents. Am J Psychiatry (1998) 2.62
In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin B. Cancer Res (2001) 2.62
Multicentre clinical trials of benzimidazolecarbamates in human echinococcosis. Bull World Health Organ (1986) 2.57
Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia. Mol Psychiatry (2007) 2.53
Schizophrenia, the heteromodal association neocortex and development: potential for a neurogenetic approach. Trends Neurosci (1996) 2.53
Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions. Nat Genet (1999) 2.53
Anticipation in bipolar affective disorder. Am J Hum Genet (1993) 2.44
Relation of infant mortality to the availability of maternity care in rural Florida. J Am Board Fam Pract (1995) 2.42
Auditory hallucinations and smaller superior temporal gyral volume in schizophrenia. Am J Psychiatry (1990) 2.41
Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture. Hum Mol Genet (1998) 2.39
A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder. Mol Psychiatry (2005) 2.32
Widespread expression of Huntington's disease gene (IT15) protein product. Neuron (1995) 2.29
fMRI analysis with the general linear model: removal of latency-induced amplitude bias by incorporation of hemodynamic derivative terms. Neuroimage (2004) 2.28
Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin. Hum Mol Genet (1997) 2.28
Residual disease following unplanned excision of soft-tissue sarcoma of an extremity. J Bone Joint Surg Am (1996) 2.26
Cephalothin in serious bacterial infection. Ann Intern Med (1966) 2.25
Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract. J Biol Chem (1998) 2.23
Two-year follow-up of inpatients with dissociative identity disorder. Am J Psychiatry (1997) 2.18
Assessing patient dependence in Alzheimer's disease. J Gerontol (1994) 2.16
Basic research by medical students. J R Soc Med (1981) 2.15
The perceived racism scale: a multidimensional assessment of the experience of white racism among African Americans. Ethn Dis (1996) 2.15
Interaction of normal and expanded CAG repeat sizes influences age at onset of Huntington disease. Am J Med Genet A (2003) 2.15
Clinical trial: the effects of a trans-galactooligosaccharide prebiotic on faecal microbiota and symptoms in irritable bowel syndrome. Aliment Pharmacol Ther (2008) 2.13
Clinical markers of early disease in persons near onset of Huntington's disease. Neurology (2001) 2.11
Joint infection by anaerobic bacteria: a case report and review of the literature. Arthritis Rheum (1969) 2.09
The plurality of long chain isoprenoid alcohols (polyprenols) from natural sources. Biochim Biophys Acta (1967) 2.07
Clinical, biochemical, and genetic characterization of a novel estrogen-dependent inherited form of angioedema. J Allergy Clin Immunol (2000) 2.07
Caudal tramadol for postoperative analgesia in pediatric hypospadias surgery. Br J Anaesth (1997) 2.05
The inositol 1,4,5,-trisphosphate receptor in cerebellar Purkinje cells: quantitative immunogold labeling reveals concentration in an ER subcompartment. J Cell Biol (1990) 2.03
Positron emission tomography reveals elevated D2 dopamine receptors in drug-naive schizophrenics. Science (1986) 2.00
Correlation between the onset age of Huntington's disease and length of the trinucleotide repeat in IT-15. Hum Mol Genet (1993) 2.00
Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length. Neurobiol Dis (1998) 1.96
Method for multimodal analysis of independent source differences in schizophrenia: combining gray matter structural and auditory oddball functional data. Hum Brain Mapp (2006) 1.96
Millon Clinical Multiaxial Inventory--II. Follow-up of patients with dissociative identity disorder. Psychol Rep (1996) 1.95
Wild-type huntingtin protects from apoptosis upstream of caspase-3. J Neurosci (2000) 1.92
Lymphocyte apoptosis: mediation by increased type 3 inositol 1,4,5-trisphosphate receptor. Science (1996) 1.92
The recidivism of mental patients: a review of past studies. Am J Orthopsychiatry (1974) 1.88
Arrhythmia and mortality after the Mustard procedure: a 30-year single-center experience. J Am Coll Cardiol (1997) 1.88
Endothelin: visualization of mRNAs by in situ hybridization provides evidence for local action. Proc Natl Acad Sci U S A (1989) 1.87
Inhibitory and blocking monoclonal antibody epitopes on merozoite surface protein 1 of the malaria parasite Plasmodium falciparum. J Mol Biol (2001) 1.87
Validity of the Dissociative Experiences Scale in screening for multiple personality disorder: a multicenter study. Am J Psychiatry (1993) 1.87
Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization. Nat Med (1999) 1.86
Anticipation and instability of IT-15 (CAG)n repeats in parent-offspring pairs with Huntington disease. Am J Hum Genet (1995) 1.84
Home care cost-effectiveness for respiratory technology-dependent children. Am J Dis Child (1991) 1.83
Audit of oxygen prescribing before and after the introduction of a prescription chart. BMJ (2000) 1.82
Protein kinase CK2 signal in neoplasia. Histol Histopathol (2001) 1.79
Cortical magnetic resonance imaging changes in elderly inpatients with major depression. Am J Psychiatry (1991) 1.78
Intracellular calcium measurements by 19F NMR of fluorine-labeled chelators. Proc Natl Acad Sci U S A (1983) 1.77
Inositol 1,4,5-trisphosphate receptors: distinct neuronal and nonneuronal forms derived by alternative splicing differ in phosphorylation. Proc Natl Acad Sci U S A (1991) 1.76
Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. Hum Mol Genet (2001) 1.74
Basal ganglia volume and proximity to onset in presymptomatic Huntington disease. Arch Neurol (1996) 1.74
Expansion of a novel CAG trinucleotide repeat in the 5' region of PPP2R2B is associated with SCA12. Nat Genet (1999) 1.74
MRI volumes of amygdala and hippocampus in non-mentally retarded autistic adolescents and adults. Neurology (1999) 1.72
The General Medical Health Rating: a bedside global rating of medical comorbidity in patients with dementia. J Am Geriatr Soc (1999) 1.71
Huntington's disease gene (IT15) is widely expressed in human and rat tissues. Neuron (1993) 1.69
Reduced basal ganglia volume in HIV-1-associated dementia: results from quantitative neuroimaging. Neurology (1993) 1.68
Rate of caudate atrophy in presymptomatic and symptomatic stages of Huntington's disease. Mov Disord (2000) 1.67
Independent component analysis of fMRI data in the complex domain. Magn Reson Med (2002) 1.65
The course of psychopathologic features in mild to moderate Alzheimer disease. Arch Gen Psychiatry (1997) 1.63
Nuclear magnetic resonance spectrometry of naturally occurring polyprenols. Anal Biochem (1967) 1.63
Long-term protection of chimpanzees against high-dose HIV-1 challenge induced by immunization. Nat Med (1997) 1.62
Nortriptyline treatment of post-stroke depression: a double-blind study. Lancet (1984) 1.62
Solution structure of an EGF module pair from the Plasmodium falciparum merozoite surface protein 1. J Mol Biol (1999) 1.61