Published in J Cell Physiol on June 01, 1976
125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts. J Cell Biol (1976) 10.88
Direct visualization of binding, aggregation, and internalization of insulin and epidermal growth factor on living fibroblastic cells. Proc Natl Acad Sci U S A (1978) 6.59
Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431. Proc Natl Acad Sci U S A (1978) 5.91
Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody. Proc Natl Acad Sci U S A (1983) 5.00
Molecular mechanism of mitogen action: processing of receptor induced by epidermal growth factor. Proc Natl Acad Sci U S A (1978) 4.31
Rapid stimulation of pinocytosis in human carcinoma cells A-431 by epidermal growth factor. J Cell Biol (1979) 2.88
Macrophage colony-stimulating factor (rM-CSF) stimulates pinocytosis in bone marrow-derived macrophages. J Exp Med (1989) 2.74
Specific radiolabeling of a cell surface receptor for epidermal growth factor. Proc Natl Acad Sci U S A (1977) 2.39
Mutations in the cytoplasmic domain of EGF receptor affect EGF binding and receptor internalization. EMBO J (1986) 2.38
Anomalous binding of epidermal growth factor to A431 cells is due to the effect of high receptor densities and a saturable endocytic system. J Cell Biol (1988) 2.31
Quantitative determination of the lateral diffusion coefficients of the hormone-receptor complexes of insulin and epidermal growth factor on the plasma membrane of cultured fibroblasts. Proc Natl Acad Sci U S A (1978) 2.26
Down regulation of epidermal growth factor receptors: direct demonstration of receptor degradation in human fibroblasts. J Cell Biol (1984) 2.12
Epidermal growth factor: biological activity requires persistent occupation of high-affinity cell surface receptors. Proc Natl Acad Sci U S A (1978) 2.02
High-affinity epidermal growth factor binding is specifically reduced by a monoclonal antibody, and appears necessary for early responses. J Cell Biol (1990) 1.78
Enhancement of epidermal regeneration by biosynthetic epidermal growth factor. J Exp Med (1986) 1.72
Effects of growth factors in vivo. I. Cell ingrowth into porous subcutaneous chambers. Am J Pathol (1987) 1.67
Sustained release of epidermal growth factor accelerates wound repair. Proc Natl Acad Sci U S A (1985) 1.66
Antibodies to the epidermal growth factor receptor block the biological activities of sarcoma growth factor. Proc Natl Acad Sci U S A (1983) 1.48
High affinity epidermal growth factor receptors on the surface of A431 cells have restricted lateral diffusion. EMBO J (1984) 1.46
Expression of annexins as a function of cellular growth state. J Cell Biol (1990) 1.42
Immunohistochemical localisation of urogastrone to human duodenal and submandibular glands. Gut (1978) 1.41
Epidermal growth factor stimulation of DNA synthesis is potentiated by compounds that inhibit its clustering in coated pits. Proc Natl Acad Sci U S A (1979) 1.36
Epidermal growth factor-induced centrosomal separation: mechanism and relationship to mitogenesis. J Cell Biol (1982) 1.35
Cell surface fibroblast growth factor and epidermal growth factor receptors are permanently lost during skeletal muscle terminal differentiation in culture. J Cell Biol (1988) 1.35
Epidermal growth factor induces rapid centrosomal separation in HeLa and 3T3 cells. J Cell Biol (1982) 1.25
Effects of epidermal growth factor and 12-O-tetradecanoylphorbol-13-acetate on metabolism of the epidermal growth factor receptor in normal human fibroblasts. Mol Cell Biol (1984) 1.24
Effect of sialoadenectomy and synthetic human urogastrone on healing of chronic gastric ulcers in rats. Gut (1986) 1.23
Dexamethasone modulates binding and action of epidermal growth factor in serum-free cell culture. Proc Natl Acad Sci U S A (1978) 1.15
Two forms of murine epidermal growth factor: rapid separation by using reverse-phase HPLC. Proc Natl Acad Sci U S A (1982) 1.14
Infection with Toxoplasma gondii results in dysregulation of the host cell cycle. Cell Microbiol (2008) 1.14
Epidermal growth factor rapidly induces a redistribution of transferrin receptor pools in human fibroblasts. Proc Natl Acad Sci U S A (1984) 1.14
Identification of a functionally important sequence in the cytoplasmic tail of integrin beta 3 by using cell-permeable peptide analogs. Proc Natl Acad Sci U S A (1996) 1.13
Mitogenic hormone-induced intracellular message: assay and partial characterization of an activator of DNA replication induced by epidermal growth factor. Proc Natl Acad Sci U S A (1980) 1.11
Lysosomotropic amines inhibit mitogenesis induced by growth factors. Proc Natl Acad Sci U S A (1981) 1.10
Down-regulation of epidermal growth factor receptor correlates with plasminogen activator activity in human A431 epidermoid carcinoma cells. Proc Natl Acad Sci U S A (1983) 1.10
Microaggregation of hormone-occupied epidermal growth factor receptors on plasma membrane preparations. EMBO J (1986) 1.08
Stabilized complexes of epidermal growth factor and its receptor on the cell surface stimulate RNA synthesis but not mitogenesis. Proc Natl Acad Sci U S A (1985) 1.06
Temperature-dependent tyrosine phosphorylation of microtubule-associated protein kinase in epidermal growth factor-stimulated human fibroblasts. Cell Regul (1991) 1.06
PI3K signaling and miRNA expression during the response of quiescent human fibroblasts to distinct proliferative stimuli. Genome Biol (2006) 1.04
Epidermal growth factor signaling and mitogenesis in Plcg1 null mouse embryonic fibroblasts. Mol Biol Cell (1998) 1.04
Identity of human epidermal growth factor (EGF) receptor with glycoprotein SA-7: evidence for differential phosphorylation of the two components of the EGF receptor from A431 cells. Proc Natl Acad Sci U S A (1982) 1.04
Neuroblast mitosis in dissociated culture: regulation and relationship to differentiation. J Cell Biol (1990) 1.03
Alteration of epidermal growth factor-dependent phosphorylation during rat liver regeneration. Proc Natl Acad Sci U S A (1982) 1.03
Stimulation of sugar uptake and thymidine incorporation in mouse 3T3 cells by calcium phosphate and other extracellular particles. Proc Natl Acad Sci U S A (1977) 1.02
Lutropin/choriogonadotropin stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the extracellularly regulated kinase 1/2 cascade. Endocrinology (2007) 0.98
Inhibition of epidermal growth factor-induced mitogenesis by amiloride and an analog: evidence against a requirement for Na+/H+ exchange. Proc Natl Acad Sci U S A (1984) 0.98
Phorbol esters potentiate tyrosine phosphorylation of epidermal growth factor receptors in A431 membranes by a calcium-independent mechanism. Proc Natl Acad Sci U S A (1984) 0.98
Epidermal growth factor and insulin cause normal chicken heart mesenchymal cells to proliferate like their Rous sarcoma virus-infected counterparts. Proc Natl Acad Sci U S A (1982) 0.92
Keratin filaments of mouse epithelial cells are rapidly affected by epidermal growth factor. J Cell Biol (1981) 0.92
Role of receptor tyrosine kinases and their ligands in glioblastoma. Cells (2014) 0.91
Basic fibroblast growth factor requires a long-lasting activation of protein kinase C to induce cell proliferation in transformed fetal bovine aortic endothelial cells. Cell Regul (1991) 0.88
Characterization of internalization and endosome formation of epidermal growth factor in transfected NIH-3T3 cells by computerized image-intensified three-dimensional fluorescence microscopy. J Cell Biol (1989) 0.87
Epidermal growth factor induces tyrosine hydroxylase in a clonal pheochromocytoma cell line, PC-G2. J Cell Biol (1980) 0.85
RNA-tumour-virus genes and transforming genes: patterns of transmission. Br J Cancer (1978) 0.78
Role of estrogens and epidermal growth factor in hepatocellular carcinoma (HCC). Dig Dis Sci (1991) 0.78
Contribution of host-derived growth factors to in vivo growth of a transplantable murine mammary carcinoma. Br J Cancer (1994) 0.78
Morphological properties of zero-stress state in rat large intestine during systemic EGF treatment. Dig Dis Sci (2003) 0.77
Effects of longterm epidermal growth factor treatment on the normal rat colon. Gut (1996) 0.76
Studies on the growth-stimulatory activity of pigeon milk--comparison and synergistic effects with serum. J Comp Physiol B (1993) 0.75
Potential of wound dressing composed of hyaluronic acid containing epidermal growth factor to enhance cytokine production by fibroblasts. J Artif Organs (2013) 0.75
Growth factor functionalized biomaterial for drug delivery and tissue regeneration. J Bioact Compat Polym (2017) 0.75
A global measure of perceived stress. J Health Soc Behav (1983) 56.90
Stress, social support, and the buffering hypothesis. Psychol Bull (1985) 19.28
Socioeconomic status and health. The challenge of the gradient. Am Psychol (1994) 13.59
Epidermal growth factor. Annu Rev Biochem (1979) 11.82
125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts. J Cell Biol (1976) 10.88
Epidermal growth factor and a new derivative. Rapid isolation procedures and biological and chemical characterization. J Biol Chem (1972) 10.86
Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N Engl J Med (1997) 8.65
Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes. J Biol Chem (1980) 7.71
Beta Alanine as a Growth Accessory for the Diphtheria Bacillus. J Bacteriol (1937) 7.51
Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431. Proc Natl Acad Sci U S A (1978) 5.91
Direct visualization of the binding and internalization of a ferritin conjugate of epidermal growth factor in human carcinoma cells A-431. J Cell Biol (1979) 5.62
Receptors for epidermal growth factor and other polypeptide mitogens. Annu Rev Biochem (1987) 5.57
Does hiatus hernia affect competence of the gastroesophageal sphincter? N Engl J Med (1971) 5.44
Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity. J Biol Chem (1980) 5.19
gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase. Science (2001) 4.90
Epidermal growth factor. J Biol Chem (1990) 4.79
Prophylactic vs therapeutic blood patch for obstetric patients with accidental dural puncture--a randomised controlled trial. Anaesthesia (2014) 4.75
IMMUNITY IN MUMPS : II. THE DEVELOPMENT OF COMPLEMENT-FIXING ANTIBODY AND DERMAL HYPERSENSITIVITY IN HUMAN BEINGS FOLLOWING MUMPS. J Exp Med (1945) 4.69
The primary structure of epidermal growth factor. J Biol Chem (1972) 4.41
Increase of the catalytic activity of phospholipase C-gamma 1 by tyrosine phosphorylation. Science (1990) 4.36
Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts. Proc Natl Acad Sci U S A (1978) 4.03
A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles. J Biol Chem (1982) 3.81
IN VITRO AND IN VIVO EFFECTS OF A NERVE GROWTH-STIMULATING AGENT ISOLATED FROM SNAKE VENOM. Proc Natl Acad Sci U S A (1956) 3.64
THE INFLUENCE OF PROTEIN INTAKE ON THE UREA CLEARANCE IN NORMAL MAN. J Clin Invest (1934) 3.60
Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells. Nature (1976) 3.56
Epidermal growth factor stimulates phosphorylation in membrane preparations in vitro. Nature (1978) 3.54
Hormone receptor topology and dynamics: morphological analysis using ferritin-labeled epidermal growth factor. Proc Natl Acad Sci U S A (1979) 3.54
Glycosyltransferase activity of Fringe modulates Notch-Delta interactions. Nature (2000) 3.51
Characterization of the binding of 125-I-labeled epidermal growth factor to human fibroblasts. J Biol Chem (1975) 3.48
Induction by EGF and interferon-gamma of tyrosine phosphorylated DNA binding proteins in mouse liver nuclei. Science (1993) 3.30
Heterogeneity of the peptide chains of gamma-globulin. Biochem J (1964) 3.25
Action of malarial antibody in vitro. Nature (1969) 3.24
Rapid enhancement of protein phosphorylation in A-431 cell membrane preparations by epidermal growth factor. J Biol Chem (1979) 3.18
Epidermal growth factor stimulates tyrosine phosphorylation of phospholipase C-II independently of receptor internalization and extracellular calcium. Proc Natl Acad Sci U S A (1989) 3.17
Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate. Leflunomide Rheumatoid Arthritis Investigators Group. Arch Intern Med (1999) 3.10
Inhibition of membrane phosphotyrosyl-protein phosphatase activity by vanadate. Biochem Biophys Res Commun (1982) 3.01
ABC of intensive care. Withdrawal of treatment. BMJ (1999) 2.96
Human epidermal growth factor: isolation and chemical and biological properties. Proc Natl Acad Sci U S A (1975) 2.95
Bone density threshold and other predictors of vertebral fracture in patients receiving oral glucocorticoid therapy. Arthritis Rheum (2003) 2.94
Social support and smoking cessation and maintenance. J Consult Clin Psychol (1986) 2.92
Rapid stimulation of pinocytosis in human carcinoma cells A-431 by epidermal growth factor. J Cell Biol (1979) 2.88
The production of migration inhibition factor by B and T cells of the guinea pig. J Exp Med (1973) 2.86
All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired. J Biol Chem (1996) 2.84
Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas. Nat Genet (1999) 2.83
Vaccination trials in rhesus monkeys with a minor, invariant, Plasmodium knowlesi 66 kD merozoite antigen. Parasite Immunol (1988) 2.79
Platelet-derived growth factor induces rapid and sustained tyrosine phosphorylation of phospholipase C-gamma in quiescent BALB/c 3T3 cells. Mol Cell Biol (1989) 2.78
In vitro comparison of netilmicin, a semisynthetic derivative of sisomicin, and four other aminoglycoside antibiotics. Antimicrob Agents Chemother (1976) 2.75
Debunking myths about self-quitting. Evidence from 10 prospective studies of persons who attempt to quit smoking by themselves. Am Psychol (1989) 2.72
Properties of protective malarial antibody. Immunology (1970) 2.65
Antiphosphotyrosine recovery of phospholipase C activity after EGF treatment of A-431 cells. Science (1988) 2.62
Rapid induction of morphological changes in human carcinoma cells A-431 by epidermal growth factors. J Cell Biol (1979) 2.61
Evidence for high-energy extraterrestrial neutrinos at the IceCube detector. Science (2013) 2.56
The Fab fragments of monoclonal IgG to a merozoite surface antigen inhibit Plasmodium knowlesi invasion of erythrocytes. Mol Biochem Parasitol (1984) 2.54
A simple technique to reduce the incidence of accidental dural puncture. Anaesthesia (2001) 2.53
Stress and immunity in humans: a meta-analytic review. Psychosom Med (1993) 2.52
Conjugational transfer of gentamicin resistance plasmids intra- and interspecifically in Staphylococcus aureus and Staphylococcus epidermidis. Antimicrob Agents Chemother (1983) 2.50
The distribution of antigenic and nonantigenic compounds within draining lymph nodes. Lab Invest (1966) 2.49
Identity and interspecific transfer of gentamicin-resistance plasmids in Staphylococcus aureus and Staphylococcus epidermidis. J Infect Dis (1980) 2.48
Enhancement of calcium uptake and phosphatidylinositol turnover by epidermal growth factor in A-431 cells. Biochemistry (1981) 2.46
Social support and adjustment to cancer: reconciling descriptive, correlational, and intervention research. Health Psychol (1996) 2.46
Nobel laureates' letter to President Bush. Washington Post (2001) 2.43
Inconsistent visual analyses of intrasubject data. J Appl Behav Anal (1979) 2.43
Interaction of activated EGF receptors with coated pit adaptins. Science (1993) 2.42
A merozoite vaccine effective against Plasmodium knowlesi malaria. Nature (1974) 2.39
Group support interventions for women with breast cancer: who benefits from what? Health Psychol (2000) 2.38
In vitro and in vivo activity of a lymphocyte and immune complex-dependent chemotactic factor for eosinophils. J Exp Med (1971) 2.36
Review of psychosocial stress and asthma: an integrated biopsychosocial approach. Thorax (1998) 2.33
Depression and immunity: a meta-analytic review. Psychol Bull (1993) 2.30
Investigation of benefits and costs of an ophthalmic outreach clinic in general practice. Br J Gen Pract (1995) 2.26
Absence of circular plasmid deoxyribonucleic acid attributable to a genetic determinant for methicillin resistance in Staphylococcus aureus. J Bacteriol (1973) 2.25
Bioengineered cardiac grafts: A new approach to repair the infarcted myocardium? Circulation (2000) 2.25
Our new President: Frank P. Brooks. Gastroenterology (1980) 2.24
Cytoplasmic pH regulation in thymic lymphocytes by an amiloride-sensitive Na+/H+ antiport. J Gen Physiol (1984) 2.23
In vitro isolation of Plasmodium knowlesi merozoites using polycarbonate sieves. Parasitology (1975) 2.23
Cimetidine in the treatment of symptomatic gastroesophageal reflux: a double blind controlled trial. Gastroenterology (1978) 2.21
Isolation of a calcium-dependent 35-kilodalton substrate for the epidermal growth factor receptor/kinase from A-431 cells. J Biol Chem (1984) 2.21
Merozoite vaccination against Plasmodium knowlesi malaria. Immunology (1975) 2.21
Mesiotemporal T2-weighted hyperintensity: neurosyphilis mimicking herpes encephalitis. AJNR Am J Neuroradiol (2001) 2.16
Down regulation of epidermal growth factor receptors: direct demonstration of receptor degradation in human fibroblasts. J Cell Biol (1984) 2.12
Structure and biological properties of immunoglobulins. Adv Immunol (1967) 2.08
Hormonal regulation of human lower esophageal sphincter competence: interaction of gastrin and secretin. J Clin Invest (1971) 2.07
Colonic myoelectric activity in the irritable bowel syndrome. Gastroenterology (1976) 2.05
Constitutive penicillinase formation in Staphylococcus aureus owing to a mutation unlinked to the penicillinase plasmid. J Bacteriol (1968) 2.03
A merozoite receptor protein from Plasmodium knowlesi is highly conserved and distributed throughout Plasmodium. J Biol Chem (1990) 2.02
First observation of PeV-energy neutrinos with IceCube. Phys Rev Lett (2013) 2.00
Rat monoclonal antibodies which inhibit the in vitro multiplication of Plasmodium knowlesi. Clin Exp Immunol (1982) 1.97
Merozoite vaccination of douroucouli monkeys against falciparum malaria. Lancet (1977) 1.95
Effect of the prophage and penicillinase plasmid of the recipient strain upon the transduction and the stability of methicillin resistance in Staphylococcus aureus. J Bacteriol (1973) 1.92
Epidermal growth factor. Location of disulfide bonds. J Biol Chem (1973) 1.90
Essential role of the tyrosine kinase substrate phospholipase C-gamma1 in mammalian growth and development. Proc Natl Acad Sci U S A (1997) 1.90
Affinity labeling of the protein kinase associated with the epidermal growth factor receptor in membrane vesicles from A431 cells. J Biol Chem (1982) 1.89
Leukotactic factors elaborated by virus-infected tissues. J Exp Med (1972) 1.89