Regenerative hyperplasia is not required for liver tumor induction in female B6C3F1 mice exposed to trihalomethanes.

PubWeight™: 1.59‹?› | Rank: Top 4%

🔗 View Article (PMID 9465273)

Published in Toxicol Appl Pharmacol on January 01, 1998

Authors

R L Melnick1, M C Kohn, J K Dunnick, J R Leininger

Author Affiliations

1: Environmental Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA. melnickr@niehs.nih.gov

Articles by these authors

(truncated to the top 100)

Herpes simplex encephalitis: vidarabine therapy and diagnostic problems. N Engl J Med (1981) 2.56

Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice. Cancer Res (1997) 2.34

Correlation of bacteria lipid composition with antibiotic resistance. J Bacteriol (1970) 1.82

Mechanistic data indicate that 1,3-butadiene is a human carcinogen. Carcinogenesis (1995) 1.65

Human exposure estimates for phthalates. Environ Health Perspect (2000) 1.53

Genetic pathways and mutation profiles of human cancers: site- and exposure-specific patterns. Carcinogenesis (2007) 1.48

Chromosome 11 allelotypes reflect a mechanism of chemical carcinogenesis in heterozygous p53-deficient mice. Carcinogenesis (2001) 1.44

Chromosome 11 loss from thymic lymphomas induced in heterozygous Trp53 mice by phenolphthalein. Toxicol Sci (2001) 1.39

Clinical trials with exogenous interferon: summary of a meeting. J Infect Dis (1979) 1.36

Correlation of regional and nonlinear formaldehyde-induced nasal cancer with proliferating populations of cells. Cancer Res (1996) 1.32

Weight of evidence versus weight of speculation to evaluate the alpha2u-globulin hypothesis. Environ Health Perspect (1997) 1.10

A convenient computer program for fitting enzymatic rate laws to steady-state data. Comput Biomed Res (1979) 1.09

Dioxin-responsive genes: examination of dose-response relationships using quantitative reverse transcriptase-polymerase chain reaction. Cancer Res (1994) 1.08

Spontaneous leprosy-like disease in a chimpanzee. J Infect Dis (1977) 1.08

Leprosy--a zoonosis. Lepr Rev (1981) 1.08

Pulmonary response to intratracheal challenge with Pasteurella haemolytica and Pasteurella multocida. Can J Comp Med (1985) 1.04

The effects of long-term ingestion of asbestos on the colon of F344 rats. Cancer (1980) 1.02

SCoP: an interactive simulation control program for micro- and minicomputers. Bull Math Biol (1986) 1.02

A computer program for analyzing enzyme kinetic data using graphical display and statistical analysis. Comput Biomed Res (1984) 0.97

Implications for risk assessment of suggested nongenotoxic mechanisms of chemical carcinogenesis. Environ Health Perspect (1996) 0.96

Computer simulation of metabolism in palmitate-perfused rat heart. I. Palmitate oxidation. Ann Biomed Eng (1983) 0.96

Hormone action at the membrane level. 3. Epinephrine interaction with the rat liver plasma membrane. Biochim Biophys Acta (1971) 0.95

Computer simulation of metabolism in palmitate-perfused rat heart. II. Behavior of complete model. Ann Biomed Eng (1983) 0.94

Distribution and fate of synthetic lipid vesicles in the mouse: a combined radionuclide and spin label study. Proc Natl Acad Sci U S A (1974) 0.93

A 90-day chloroform inhalation study in female and male B6C3F1 mice: implications for cancer risk assessment. Fundam Appl Toxicol (1996) 0.92

Using structural information to create physiologically based pharmacokinetic models for all polychlorinated biphenyls. Toxicol Appl Pharmacol (1997) 0.92

Loss of heterozygosity frequency at the Trp53 locus in p53-deficient (+/-) mouse tumors is carcinogen-and tissue-dependent. Carcinogenesis (2001) 0.91

A glioma in the spinal cord of a cat. Vet Pathol (1982) 0.91

Adaptation of a colorimetric microtitration assay for quantifying Pasteurella haemolytica A1 leukotoxin and antileukotoxin. Am J Vet Res (1987) 0.91

In vivo distribution of vesicles loaded with radiopharmaceuticals: a study of different routes of administration. J Nucl Med (1975) 0.91

Computer simulation of metabolism in pyruvate-perfused rat heart. II. Krebs cycle. Am J Physiol (1979) 0.90

Hematologic toxicity of AZT and ddC administered as single agents and in combination to rats and mice. Fundam Appl Toxicol (1991) 0.89

Computer simulation of metabolism in pyruvate-perfused rat heart. V. Physiological implications. Am J Physiol (1979) 0.89

Metabolic network sensitivity analysis. J Theor Biol (1982) 0.89

Biochemical responses of rat and mouse lung to inhaled nickel compounds. Toxicology (1989) 0.88

Leprosy in a chimpanzee. Morphology of the skin lesions and characterization of the organism. Vet Pathol (1978) 0.86

From the National Institute of Allergy and Infectious Diseases. Update on clinical trials with exogenous interferon. J Infect Dis (1980) 0.86

Evaluation of a calculolytic diet in female dogs with induced struvite urolithiasis. Am J Vet Res (1984) 0.86

Gastric candidiasis in laboratory-reared brown lemmings. J Am Vet Med Assoc (1979) 0.86

Computer simulation of ischemic rat heart purine metabolism. II. Model behavior. Am J Physiol (1977) 0.86

Kinetic analysis of monocarboxylate uptake into perfused rat hearts. J Mol Cell Cardiol (1985) 0.86

Interferon, an antiviral drug for use in man. Tex Rep Biol Med (1977) 0.85

Kidney and urinary bladder lesions in F344/N rats and B6C3F1 mice after 13 weeks of 2,2-bis(bromomethyl)-1,3-propanediol administration. Fundam Appl Toxicol (1989) 0.84

Comparative inhalation toxicity of nickel subsulfide to F344/N rats and B6C3F1 mice exposed for 12 days. Fundam Appl Toxicol (1987) 0.83

Bromodichloromethane, a trihalomethane that produces neoplasms in rodents. Cancer Res (1987) 0.83

Production and partial characterization of monoclonal antibodies to Pasteurella haemolytica A1 capsular polysaccharide and lipopolysaccharide. Am J Vet Res (1988) 0.83

Chemical-specific alterations in ras, p53, and beta-catenin genes in hemangiosarcomas from B6C3F1 mice exposed to o-nitrotoluene or riddelliine for 2 years. Toxicol Appl Pharmacol (2003) 0.83

Systems analysis in enzyme kinetics. CRC Crit Rev Bioeng (1977) 0.82

Computer simulation of metabolism in pyruvate-perfused rat heart. III. Pyruvate dehydrogenase. Am J Physiol (1979) 0.82

Distribution of adenine nucleotides in the perfused rat heart. Am J Physiol (1977) 0.82

Carcinogenesis bioassay of allyl isothiocyanate. Fundam Appl Toxicol (1983) 0.81

Neuroepithelial tumor of the optic nerve in a horse. Cornell Vet (1983) 0.81

Computer simulation of metabolism in pyruvate-perfused rat heart. I. Model construction. Am J Physiol (1979) 0.81

Effect of individual versus group caging on the incidence of pituitary and Leydig cell tumors in F344 rats: proposed mechanism. Med Hypotheses (1998) 0.81

A physiologically based pharmacokinetic model for inhalation and intravenous administration of naphthalene in rats and mice. Toxicol Appl Pharmacol (2001) 0.81

Computer simulation of the fructose bisphosphatase/phosphofructokinase couple in rat liver. Eur J Biochem (1979) 0.80

Medical dissolution of canine struvite uroliths. Vet Clin North Am Small Anim Pract (1986) 0.80

Pathology of tumours in laboratory animals. Tumours of the rat. Tumours of the salivary and lacrimal glands. IARC Sci Publ (1990) 0.80

Animal studies of potential chronic lung disease of workers in swine confinement buildings. Am J Vet Res (1984) 0.80

Computer modeling of muscle phosphofructokinase kinetics. J Theor Biol (1983) 0.80

Computer simulation of metabolism in palmitate-perfused rat heart. III. Sensitivity analysis. Ann Biomed Eng (1983) 0.79

Developmental toxicity of orally administered 2',3'-dideoxycytidine in mice. Teratology (1990) 0.79

Somatic mutation databases as tools for molecular epidemiology and molecular pathology of cancer: proposed guidelines for improving data collection, distribution, and integration. Hum Mutat (2009) 0.79

Malignant squamous cell thymoma in a horse. Vet Pathol (1986) 0.79

Spontaneous thymoma in a juvenile cynomolgus macaque (Macaca fascicularis). Toxicol Pathol (2011) 0.79

Computer simulation of entry into glycolysis and lactate output in the ischemic rat heart. J Mol Cell Cardiol (1978) 0.79

Toxicity of 8-methoxypsoralen, 5-methoxypsoralen, 3-carbethoxypsoralen, or 5-methylisopsoralen with ultraviolet radiation in the hairless (HRA/Skh) mouse. Toxicol Appl Pharmacol (1987) 0.79

Measurement of micronucleated erythrocytes and DNA damage during chronic ingestion of phenolphthalein in transgenic female mice heterozygous for the p53 gene. Environ Mol Mutagen (1998) 0.79

Nephrotoxicity of S-(2-chloro-1,1,2-trifluoroethyl)glutathione and S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine, the glutathione and cysteine conjugates of chlorotrifluoroethene. J Pharmacol Exp Ther (1985) 0.79

A graph-theoretical analysis of metabolic regulation. J Theor Biol (1983) 0.78

The immunotoxicity of three nickel compounds following 13-week inhalation exposure in the mouse. Fundam Appl Toxicol (1990) 0.78

Influences of exercise intensity, age, and medication on resting systolic blood pressure of SHR populations. J Appl Physiol Respir Environ Exerc Physiol (1983) 0.78

Vesicle interactions with polyamino acids and antibody: in vitro and in vivo studies. J Nucl Med (1975) 0.78

Detection of immunoglobulin G to Pasteurella haemolytica capsular polysaccharide by enzyme-linked immunosorbent assay. J Clin Microbiol (1987) 0.78

Sensitivity to values of the rate constants in a neurochemical metabolic model. J Theor Biol (1983) 0.78

Brugia pahangi: histopathological study of golden hamsters. Exp Parasitol (1976) 0.78

Computer simulation of metabolism in pyruvate-perfused rat heart. IV. Model behavior. Am J Physiol (1979) 0.78

Possible mechanisms of induction of renal tubule cell neoplasms in rats associated with alpha 2u-globulin: role of protein accumulation versus ligand delivery to the kidney. IARC Sci Publ (1999) 0.78

Struvite urolithiasis in animals and man: formation, detection, and dissolution. Adv Vet Sci Comp Med (1985) 0.77

Voluntary exercise and its effects on young SHR and stroke-prone hypertensive rats. J Appl Physiol (1985) (1986) 0.77

Alteration of mammalian cells by interaction with artificial lipid vesicles. Cancer Res (1976) 0.77

A 90-day chloroform inhalation study in F-344 rats: profile of toxicity and relevance to cancer studies. Fundam Appl Toxicol (1996) 0.77

A mathematical model of production, distribution, and metabolism of melatonin in mammalian systems. Toxicol Appl Pharmacol (1997) 0.77

Summary of the National Toxicology Program benzidine dye initiative. Environ Health Perspect (1994) 0.77

Reproductive toxicology of methyldopa in male F344/N rats. Toxicology (1986) 0.77

Toxicity and carcinogenicity of chlorodibromomethane in Fischer 344/N rats and B6C3F1 mice. Fundam Appl Toxicol (1985) 0.77

Exercise training and incidence of cerebrovascular lesions in stroke-prone spontaneously hypertensive rats. J Appl Physiol (1985) (1990) 0.77

Computer simulation of ischemic rat heart purine metabolism. I. Model construction. Am J Physiol (1977) 0.77

Teratogenic effect of acetohydroxamic acid in clinically normal beagles. Am J Vet Res (1986) 0.77

Chemicals associated with decreases in the incidence of mononuclear cell leukemia in the Fischer rat. Toxicol Pathol (1997) 0.77

Mitochondrial DNA sequence and phylogenetic evaluation of geographically disparate Sus scrofa breeds. Anim Biotechnol (2015) 0.77

Comparative inhalation toxicity of nickel sulfate to F344/N rats and B6C3F1 mice exposed for twelve days. Fundam Appl Toxicol (1988) 0.76

Effect of detergents and sodium fluoride on the enzyme activities of the rat liver plasma membrane. Biochim Biophys Acta (1972) 0.76

Acute lung lesions due to zirconium and aluminum compounds in hamsters. Arch Pathol Lab Med (1977) 0.76

The combined effects of asbestos ingestion and localized X-irradiation of the colon in rats. J Environ Pathol Toxicol Oncol (1984) 0.76

Malignant neuroblastoma in a cow. Vet Pathol (1984) 0.76

Leprosy in a chimpanzee. Postmortem lesions. Int J Lepr Other Mycobact Dis (1980) 0.75

Development of renal lesions in dogs after 11/12 reduction of renal mass. Influences of dietary protein intake. Lab Invest (1988) 0.75

Toxicokinetics of bis(2-chloroethoxy)methane following intravenous administration and dermal application in male and female F344/N rats and B6C3F1 mice. Toxicol Lett (2011) 0.75

Lung neoplasms in rodents after chronic administration of dimethyl hydrogen phosphite. Cancer Res (1986) 0.75