Published in FASEB J on March 01, 1998
The hemopexin domain of matrix metalloproteinase-9 activates cell signaling and promotes migration of schwann cells by binding to low-density lipoprotein receptor-related protein. J Neurosci (2008) 1.60
Ligand binding to LRP1 transactivates Trk receptors by a Src family kinase-dependent pathway. Sci Signal (2009) 1.36
TNFalpha-induced MMP-9 promotes macrophage recruitment into injured peripheral nerve. Mol Cell Neurosci (2005) 1.30
Molecular dissection of the human alpha2-macroglobulin subunit reveals domains with antagonistic activities in cell signaling. J Biol Chem (2008) 1.11
Low density lipoprotein receptor-related protein (LRP1) regulates Rac1 and RhoA reciprocally to control Schwann cell adhesion and migration. J Biol Chem (2010) 1.01
GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin. Proc Natl Acad Sci U S A (2013) 0.99
A shed form of LDL receptor-related protein-1 regulates peripheral nerve injury and neuropathic pain in rodents. J Clin Invest (2008) 0.99
The unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury. J Neurosci (2011) 0.98
The protective role of prosaposin and its receptors in the nervous system. Brain Res (2014) 0.94
Saposin C promotes survival and prevents apoptosis via PI3K/Akt-dependent pathway in prostate cancer cells. Mol Cancer (2004) 0.91
Spinal p38 mitogen-activated protein kinase mediates allodynia induced by first-degree burn in the rat. J Neurosci Res (2009) 0.89
J3-crystallin of the jellyfish lens: similarity to saposins. Proc Natl Acad Sci U S A (2001) 0.89
Erythropoietin promotes Schwann cell migration and assembly of the provisional extracellular matrix by recruiting beta1 integrin to the cell surface. Glia (2010) 0.86
Neurolysosomal pathology in human prosaposin deficiency suggests essential neurotrophic function of prosaposin. Acta Neuropathol (2006) 0.83
Regulation of cytokine expression by Schwann cells in response to α2-macroglobulin binding to LRP1. J Neurosci Res (2011) 0.83
Hunting for the function of orphan GPCRs - beyond the search for the endogenous ligand. Br J Pharmacol (2014) 0.82
Differential distribution of PI3K isoforms in spinal cord and dorsal root ganglia: potential roles in acute inflammatory pain. Pain (2014) 0.81
GPR37 protein trafficking to the plasma membrane regulated by prosaposin and GM1 gangliosides promotes cell viability. J Biol Chem (2013) 0.80
Drug Discovery Opportunities at the Endothelin B Receptor-Related Orphan G Protein-Coupled Receptors, GPR37 and GPR37L1. Front Pharmacol (2015) 0.79
Decrease in prosaposin in the Dystrophic mdx mouse brain. PLoS One (2013) 0.78
Low-density lipoprotein receptor related protein-1 (LRP1)-dependent cell signaling promotes neurotrophic activity in embryonic sensory neurons. PLoS One (2013) 0.76
A prosaposin-derived Peptide alleviates kainic Acid-induced brain injury. PLoS One (2015) 0.76
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Cell death prevention, mitogen-activated protein kinase stimulation, and increased sulfatide concentrations in Schwann cells and oligodendrocytes by prosaposin and prosaptides. Proc Natl Acad Sci U S A (1997) 1.05
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Model SV40-transformed fibroblast lines for metabolic studies of human prosaposin and acid ceramidase deficiencies. Clin Chim Acta (1997) 0.95
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