Published in J Neurosci Res on March 01, 2009
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The Rheb-mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord. J Neurosci (2009) 1.48
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Erythropoietin promotes MCF-7 breast cancer cell migration by an ERK/mitogen-activated protein kinase-dependent pathway and is primarily responsible for the increase in migration observed in hypoxia. J Biol Chem (2005) 1.21
Characterization of the acute and persistent pain state present in K/BxN serum transfer arthritis. Pain (2010) 1.20
Spinal TLR4 mediates the transition to a persistent mechanical hypersensitivity after the resolution of inflammation in serum-transferred arthritis. Pain (2011) 1.17
Constitutive spinal cyclooxygenase-2 participates in the initiation of tissue injury-induced hyperalgesia. J Neurosci (2004) 1.14
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Inhibition of p38 MAP kinase activity enhances axonal regeneration. Exp Neurol (2003) 1.13
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Peripheral inflammatory disease associated with centrally activated IL-1 system in humans and mice. Proc Natl Acad Sci U S A (2012) 1.11
Low-density lipoprotein receptor-related protein 1 is an essential receptor for myelin phagocytosis. J Cell Sci (2009) 1.09
Analysis of dosing regimen and reproducibility of intraspinal grafting of human spinal stem cells in immunosuppressed minipigs. Cell Transplant (2010) 1.08
Role of spinal microglia in visceral hyperalgesia and NK1R up-regulation in a rat model of chronic stress. Gastroenterology (2008) 1.07
Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages. J Leukoc Biol (2010) 1.05
Pathogenesis of spinally mediated hyperalgesia in diabetes. Diabetes (2007) 1.03
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A shed form of LDL receptor-related protein-1 regulates peripheral nerve injury and neuropathic pain in rodents. J Clin Invest (2008) 0.99
Collagen antibody-induced arthritis evokes persistent pain with spinal glial involvement and transient prostaglandin dependency. Arthritis Rheum (2012) 0.98
Stem cells: comprehensive treatments for amyotrophic lateral sclerosis in conjunction with growth factor delivery. Growth Factors (2009) 0.98
The unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury. J Neurosci (2011) 0.98
Inflammatory hyperalgesia induces essential bioactive lipid production in the spinal cord. J Neurochem (2010) 0.97
Inhibition of spinal constitutive NOS-2 by 1400W attenuates tissue injury and inflammation-induced hyperalgesia and spinal p38 activation. Eur J Neurosci (2007) 0.95
ISSLS prize winner: Erythropoietin inhibits spinal neuronal apoptosis and pain following nerve root crush. Spine (Phila Pa 1976) (2003) 0.92
Release of prostaglandin E(2) and nitric oxide from spinal microglia is dependent on activation of p38 mitogen-activated protein kinase. Anesth Analg (2010) 0.90
Measurement of peripheral muscle resistance in rats with chronic ischemia-induced paraplegia or morphine-induced rigidity using a semi-automated computer-controlled muscle resistance meter. J Neurotrauma (2005) 0.90
Low-density lipoprotein receptor-related protein 1 (LRP1)-dependent cell signaling promotes axonal regeneration. J Biol Chem (2013) 0.89
TNF-alpha and phosphorylation of ERK in DRG and spinal cord: insights into mechanisms of sciatica. Spine (Phila Pa 1976) (2006) 0.88
Role of spinal p38alpha and beta MAPK in inflammatory hyperalgesia and spinal COX-2 expression. Neuroreport (2010) 0.87
Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats. Diabetes (2002) 0.87
Erythropoietin promotes Schwann cell migration and assembly of the provisional extracellular matrix by recruiting beta1 integrin to the cell surface. Glia (2010) 0.86
Interleukin-6: a local pain trigger? Arthritis Res Ther (2010) 0.85
Schwann cell LRP1 regulates remak bundle ultrastructure and axonal interactions to prevent neuropathic pain. J Neurosci (2013) 0.85
Rat substrains differ in the magnitude of spontaneous locomotor recovery and in the development of mechanical hypersensitivity after experimental spinal cord injury. J Neurotrauma (2013) 0.85
Spinal actions of lipoxin A4 and 17(R)-resolvin D1 attenuate inflammation-induced mechanical hypersensitivity and spinal TNF release. PLoS One (2013) 0.85
A derivative of the plasma protease inhibitor alpha(2)-macroglobulin regulates the response to peripheral nerve injury. J Neurochem (2007) 0.84
Combinational spinal GAD65 gene delivery and systemic GABA-mimetic treatment for modulation of spasticity. PLoS One (2012) 0.84
Influence of rat substrain and growth conditions on the characteristics of primary cultures of adult rat spinal cord astrocytes. J Neurosci Methods (2011) 0.83
Suppression of stretch reflex activity after spinal or systemic treatment with AMPA receptor antagonist NGX424 in rats with developed baclofen tolerance. Br J Pharmacol (2010) 0.83
Regulation of cytokine expression by Schwann cells in response to α2-macroglobulin binding to LRP1. J Neurosci Res (2011) 0.83
Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations. Pain (2016) 0.80
Pentoxifylline and propentofylline prevent proliferation and activation of the mammalian target of rapamycin and mitogen activated protein kinase in cultured spinal astrocytes. J Neurosci Res (2012) 0.79
Pig models of neurodegenerative disorders: Utilization in cell replacement-based preclinical safety and efficacy studies. J Comp Neurol (2014) 0.79
Low-speed subcellular fractionation method for determining noxious stimulus-evoked spinal neurokinin-1 receptor internalization. J Neurosci Methods (2006) 0.78
Identification and quantification of neuropeptides in naïve mouse spinal cord using mass spectrometry reveals [des-Ser1]-cerebellin as a novel modulator of nociception. J Neurochem (2014) 0.77
K/BxN serum transfer arthritis as a model of inflammatory joint pain. Methods Mol Biol (2012) 0.77
Cross-centre replication of suppressed burrowing behaviour as an ethologically relevant pain outcome measure in the rat: a prospective multicentre study. Pain (2016) 0.77
Effective long-term immunosuppression in rats by subcutaneously implanted sustained-release tacrolimus pellet: effect on spinally grafted human neural precursor survival. Exp Neurol (2013) 0.76
BDNF gene delivery within and beyond templated agarose multi-channel guidance scaffolds enhances peripheral nerve regeneration. J Neural Eng (2016) 0.75
Synaptogenesis and amino acid release from long term embryonic rat spinal cord neuronal culture using tissue culture inserts. J Neurosci Methods (2005) 0.75
Cross-centre replication of suppressed burrowing behaviour as an ethologically relevant pain outcome measure in the rat: a prospective multicentre study. Pain (2016) 0.75